• Journal of the Korean association of regional geographers
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• v.3 no.1
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• pp.13-34
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• 1997

The impact of a central place on daily living over wide outlying territory has been one of traditional subjects in the field of urban geography. The flow of rural population toward the central city of Chinju characterizes the population movement in Western Kyungnam, where the spillover of urban population into outlying areas, an especially prominent phenomenon in American society, does not occur. The central city of Chinju is supposed to be the most favored settlement area in Western Kyungnam. More than two thousands of teachers. who live in Chinju, cross the city boundary each morning to do their jobs in Western Kyungnam. But only ninety teachers living outside Chinju commute to the workplace in the city. The teachers willingly spend hours commuting each day to enjoy better quality of life in the central city. In fact, the central city of Chinju functions as bedroom communities for many middle-class workers in Western Kyungnam. On the basis of teachers' commuting behavior, four levels of Chinju's urban spheres are identified in Western Kyungnam. As Table-6 and Figure-2 show, the first-order level of Chinju's sphere includes most Myuns of Sanchung/Hadong Guns and some Myuns of Sachun/Gosung Guns. The second-order level comprises Sanchung/Sachun Eubs and many Myuns of Sachun /Gosung Guns. The third-order level is made up of Samchunpo, Hadong/Gosung/Eryung/Namhae/Habchun/Hamyang Eups, and many Myuns of Eryung/Namhae/Habchun Guns. And all of Guchang Gun and most Myuns of Hamyang Gun belong to the fourth-order level of Chinju's sphere. The influence sphere of Metropolitan Chinju is extended farther in the direction of less competition with other metropolises. Such a situation occurs to the west and south of Chinju. Daily commuting, defined as the journeys to and from work, is an excellent indicator for delimiting urban spheres of influence.

• The Journal of Engineering Geology
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• v.16 no.4 s.50
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• pp.437-453
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• 2006

More than 3,000 landslides were occurred by torrential rains in Gangneung area due to the typhoon Rusa in 2002. In order to analyze the landslide origin and its geometric characteristics, 1,365 landslide data were collected from the field survey of Sacheon, Jumunjin, and Yeongok areas in which the intensive landslides took place. The average landslide size in the study area was composed of 10m width, 30m length, and $21^{\circ}{\sim}35^{\circ}$ slope angle, and the plane view of landslides A-type (i.e. wide shape of lower part) that contains approximately 50.5% of the landslides commonly occurred. In particular the area of Sacheon heavily damaged by mountain fires had more occurrence of landslides than other areas. The landslides of uniform tendency of slope direction were examined resulted from the contribution of topographic characteristics due to the weathering and wind direction during heavy rainfalls. In order to analyze the direction of joint, 249 orientation data were collected from the study area. The window method was employed to determine the characteristics of joint density in 51 locations of the study area. The results showed that many landslides occurred in the areas of joint density with the range of $0.05{\sim}0.1$.

• The Korean Journal of Pharmacology
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• v.31 no.2
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• pp.195-206
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• 1995

The study was undertaken to examine the possibility of the involvement of $K^+$ channels in the mechanism of relaxant-action of imipramine on the isolated canine detrusor muscle strips. Canine urinary bladder were isolated, and smooth muscle strips of 15 mm long and 2 mm wide from the mid-portion of anterior wall were made in the Tyrode solution of $0{\sim}4^{\circ}C$. The strips were prepared for isometric myography in Biancani's isolated muscle chamber containing 1 ml of Tyrode solution, which was maintained with pH 7.4 by aeration with $95%\;O_2/5%CO_2\;at\;37^{\circ}C$. RP 52891, a non-specific $K^+$ channel opener, concentration-dependently suppressed the spontaneous phasic contractions of the detrusor strips. Imipramine, a tricyclic antidepressant, also reduced the spontaneous contractions in a concentration-dependent manner. RP 52891 was more potent than imipramine(p<0.05), and Imipramine was more efficient than RP 52891(p<0.05).Procaine, a voltage-dependent $K^+$ channel blocker, glibenclamide, an ATP-dependent $K^+$ channel blocker, and apamin, a calcium-dependent $K^+$ channel blocker antagonized the relaxant effect of RP 52891, but not of imipramine. Imipramine reduced the electric field stimulation (EFS) -induced contractions concentration-dependently. None of the $K^+$ channel blockers employed for this study, procaine, glibenclamide or apamin antagonized the inhibitory action of imipramine on the EFS-induced contraction. These results suggest that in canine detrusor, the $K^+$ channels of the characteristics of voltage-dependent, ATP-dependent and/or calcium-dependent are exist, and the inhibitory action of imipramine on the contractility of the detrusor is independent from the $K^+$ channels.

• Journal of The Korea Institute of Healthcare Architecture
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• v.21 no.4
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• pp.27-36
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• 2015

Purpose: Of late, the focus of service design is moving toward emphasizing customer satisfaction and taking users' experience more seriously. In addition to the change in perspective in service design, scholars in this area are paying more attention to service design methodology and process, as well as its theory and real-world case studies. In the case of medical space, there have been few studies in attempting to apply service design methods useful for deriving user-focused results. The author of this paper believes, however, case study-oriented approaches are more needed in this area rather than ones focusing on theoretical aspects. The author hopes thereby to expand the horizon to practical application of spatial design beyond service design methodology. Methods: In order to incorporate the strengths of service design methodology that can reflect a variety of user opinions, this study will introduce diverse tools in the framework of double diamond process. In addition, it will present field cases that successfully brought about best results in medical space design. It will end with summarizing the ideal process of medical space design which is reasonable and comprehensive. Results: Medical service encompasses preventive medicine as well as treatment of existing medical conditions. A study in establishing the platform of medical service design consists of a wide range of trend research, followed by the summary of two-matrix design classification based on results of the trend research. The draft of design process is divided into five stages composed of basic tools for establishing spatial flow lines created by matching service design tools with each stage of space design processes. In all this, most important elements to consider are communication and empathy. When service design is actually applied to space design, one can see that output has reflected the users' needs very well. The service design process for user-oriented medical space can thus be established by interactions on the final outcome and feedback on the results. Implications: One can see that the service design with the hospital at its center produces the result that encompasses the user's needs best. If the user-focused service design process for medical space can be extended to other space designs, the author believes that it would enhance the level of satisfaction for users and minimize trials and errors.

• Journal of radiological science and technology
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• v.33 no.4
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• pp.387-394
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• 2010

In the field of healthcare, the conventional sterilization treatments have been replaced by irradiation methods which are in accordance with internationally well established quality standards. The quality control in radiation sterilization assures that the absorbed dose of the irradiated material is in agreement with its requirements and standards. The electron beam irradiation requires technical assessments of more process parameters than gamma irradiation does. Korea has witnessed wide uses of electron accelerators since early 2000 but there hasn't been research experiences relating to quality system in accordance with international standards. The new large scale e-beam irradiation system with the specification of 10 MeV, 8 kW was installed and operated in 2008 by Seoul Radiology Services Co. It consists of the electron accelerator, product handling system, safety, documentation and control subsystems into an integrated system to meet the requirement of the Good Manufacturing Practice such as process quality assurance and management of product tracking records. To implement the international standard such as EN ISO11137, it is necessary to understand the purposes aimed in the standard and carry out the tests following the procedures required. This study presented the specification of the e-beam facility and showed what its design requirements and features are. The test results on a variety of process parameters were presented and validated it they are within the required limits.

• The Korean Journal of Mycology
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• v.45 no.1
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• pp.74-82
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• 2017

Lisianthus (Eustoma grandiflorum) is a flowering ornamental plant used widely in Korea. In 2015, wilting, damping-off, stunting, and root rot symptoms were observed in lisianthus plants of Yeoju and Gimhae, Korea. Affected seedlings appeared yellow and showed poor development of root systems in the field and in nursery boxes. Furthermore, affected plants were yellow, stunted, and died at approximately 2-3 months after transplanting. Fusarium species were consistently isolated from the basal stems of diseased plants. Nine isolates were identified as Fusarium solani based on morphological characteristics. Macroconidia of isolates were relatively wide, straight-to-slightly curved, and microconidia formed in false heads on long monophialides. Abundant chlamydospores were produced at the middle or tips of hyphae. To confirm this identification, a molecular analysis of the translation elongation factor 1 alpha (TEF) and RNA polymerase II subunit (RPB2) genes was conducted. The sequences of TEF and RPB2 showed 99.2-99.9% and 98.0-98.1% similarity, respectively, to those of reference F. solani strains in NCBI GenBank. Pathogenicity was tested using root dipping inoculation of healthy lisianthus seedlings. Symptoms were observed within 7 days of inoculation only in inoculated plants. This is the first report of F. solani causing Fusarium root rot on lisianthus in Korea.

• Tunnel and Underground Space
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• v.16 no.3 s.62
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• pp.251-258
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• 2006

In this paper, the applicability to the Korean rock condition of using the deformation moduli based on Rock Mass Rating (RMR) and Pressuremeter Test (PMT) is evaluated. The correlations among deformation moduli and various rock properties were also analyzed. It appears that the existing correlations using RMR overestimate the deformation moduli and wide variation was found between predicted moduli using these correlations and measured values. As for the correlations among the deformation moduli and various rock properties, Rock Quality Designation (RQD) and unconfined compressive strength (UCS) were found to correlate to deformation moduli reasonably well, but joint spacing and joint conditions appear to correlate poorly to RQD and UCS. Additionally, groundwater can not be correlated with the modulus values. While the depth has very little contribution to deformation modulus, it should be factored in the simple regression analyses with various rock mass properties, especially with the correlations made with UCS, RQD etc. With the deficiencies of these correlations, more in depth analysis techniques such as multivariate correlations may be to reliably estimate deformation modulus of rock mass.

• Journal of Korean Society of Transportation
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• v.27 no.5
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• pp.97-111
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• 2009

Image-based traffic information collection systems have entered widespread adoption and use in many countries since these systems are not only capable of replacing existing loop-based detectors which have limitations in management and administration, but are also capable of providing and managing a wide variety of traffic related information. In addition, these systems are expanding rapidly in terms of purpose and scope of use. Currently, the utilization of image processing technology in the field of traffic accident management is limited to installing surveillance cameras on locations where traffic accidents are expected to occur and digitalizing of recorded data. Accurately recording the sequence of situations around a traffic accident in a signal intersection and then objectively and clearly analyzing how such accident occurred is more urgent and important than anything else in resolving a traffic accident. Therefore, in this research, we intend to present a technology capable of overcoming problems in which advanced existing technologies exhibited limitations in handling real-time due to large data capacity such as object separation of vehicles and tracking, which pose difficulties due to environmental diversities and changes at a signal intersection with complex traffic situations, as pointed out by many past researches while presenting and implementing an active and environmentally adaptive methodology capable of effectively reducing false detection situations which frequently occur even with the Gaussian complex model analytical method which has been considered the best among well-known environmental obstacle reduction methods. To prove that the technology developed by this research has performance advantage over existing automatic traffic accident recording systems, a test was performed by entering image data from an actually operating crossroad online in real-time. The test results were compared with the performance of other existing technologies.

• Journal of Veterinary Clinics
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• v.31 no.6
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• pp.502-506
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• 2014

Recently nano particles have proven for wide array of bioactive properties. In the present study, antibacterial properties of chitosan silver nano composites (CAgNCs) were investigated against fish pathogenic Edwardsiella tarda. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of CAgNCs against E. tarda were $25{\mu}g/mL$ and $125{\mu}g/mL$, respectively. The field emission scanning electron microscope (FE-SEM) image of CAgNCs treated E. tarda showed the strongly damaged bacteria cells than non-treated bacteria. Furthermore, treatment of CAgNCs induced the level of intracellular reactive oxygen species (ROS) in E. tarda cells in concentration and time dependent manner suggesting that it may generate oxidative stress leading to bacterial cell death. In addition, MTT assay results showed that the lowest cell viability at $100{\mu}g/mL$ of CAgNCs treated E. tarda. Overall results of this study suggest that CAgNCs is a potential antibacterial agent to control pathogenic bacteria.

• ALGAE
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• v.35 no.1
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• pp.45-59
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• 2020

To investigate the spatio-temporal distributions of the mixotrophic dinoflagellate Yihiella yeosuensis in Korean coastal waters and its grazing impact on prey populations, water samples were seasonally collected from 28 stations in the East, West, and South Seas of Korea and Jeju Island from April 2015 to October 2018. The abundances of Y. yeosuensis in the water samples were quantified using quantitative real-time polymerase chain reaction (qPCR). Simultaneously, the physical and chemical properties of water from all sampled stations were determined, and the abundances of the optimal prey species of Y. yeosuensis, the prasinophyte Pyramimonas sp. and the cryptophyte Teleaulax amphioxeia, were quantified using qPCR. Y. yeosuensis has a wide distribution, as is reflected by the detection of Y. yeosuensis cells at 23 sampling stations; however, this distribution has a strong seasonality, which is indicated by its detection at 22 stations in summer but only one station in winter. The abundance of Y. yeosuensis was significantly and positively correlated with those of Pyramimonas sp. and T. amphioxeia, as well as with water temperature. The highest abundance of Y. yeosuensis was 48.5 cells mL^-1 in Buan in July 2017, when the abundances of Pyramimonas sp. and T. amphioxeia were 917.6 and 210.4 cells mL^-1, respectively. The growth rate of Y. yeosuensis on Pyramimonas sp., calculated by interpolating the growth rates at the same abundance, was 0.49 d^-1, which is 37% of the maximum growth rate of Y. yeosuensis on Pyramimonas sp. obtained in the laboratory. Therefore, the field abundance of Pyramimonas sp. obtained in the present study can support a moderate positive growth of Y. yeosuensis. The maximum grazing coefficient for Y. yeosuensis on the co-occurring Pyramimonas sp. was 0.42 d^-1, indicating that 35% of the Pyramimonas sp. population were consumed in 1 d. Therefore, the spatio-temporal distribution of Y. yeosuensis in Korean coastal waters may be affected by those of the optimal prey species and water temperature. Moreover, Y. yeosuensis may potentially have considerable grazing impacts on populations of Pyramimonas sp.