• The Journal of the Korea Contents Association
• /
• v.10 no.7
• /
• pp.297-304
• /
• 2010

As Small Intestine Absorptive Epithelium Cells are surrounded by mucus polysaccharide and lymphocytes and mitochondria, they are sensitive to radiation energy. Damaged cells lead to a deficiency of nutrients and the imbalance of electrolyte metabolism, which in turn can becomes a major cause of an intestine tract death. This research observed ultra structures after injecting propolis into the abdominal cavity in order to reveal the radiation damage mechanism and radioprotection effect of intestine absorptive epithelium cells. The result of this research's observation found that stenosis occurred in the small intestine in some tissues 20 days after 5Gy irradiation, their surface turned black, and their elasticity dropped. Through observation with an optical microscope, it was found that the size of the goblet cells decreased, while the paneth granulate cells atrophied and were vacuolated. Observation with an transmission electron microscope(TEM) revealed that while microvill and lysosome were normally observed in jejunum tissues, mitochondria membrane was damaged and uneven surfaces were formed on lymphocytes. The membrane of absorptive epithelium cells hypertrophied in tissues of the ileum, and vacuole was observed. However, the observation after injecting propolis into the abdominal cavity found that mitochondria damage dropped dramatically, and radioprotection effects were to some extent confirmed, considering that glycocalyx of villi was clear, and M cells could be observed.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.5
• /
• pp.310-316
• /
• 2021

Conventional satellites are generally large satellites that are multi-functional and have high performance. However, small satellites have been gradually drawing attention since the recent development of lightweight and integrated electric, electronic, and optical technologies. As the size and weight of a satellite decrease, the barrier to satellite development is becoming lower due to the cost of manufacture and cheaper launch. However, solar panels are essential for the power supply of satellites but have limitations in miniaturization and weight reduction because they require a large surface area to be efficiently exposed to sunlight. Space solar cells must be manufactured in consideration of various space environments such as spacecraft and environments with solar thermal temperatures. It is necessary to study structural materials for lightweight and high-efficiency solar cells by applying an unfolding mechanism that optimizes the surface-to-volume ratio. Currently, most products are developed and operated as solar cell panels for space applications with a triple-junction structure of InGaP/GaAs/Ge materials for high efficiency. Furthermore, multi-layered junctions have been studied for ultra-high-efficiency solar cells. Flexible thin-film solar cells and organic-inorganic hybrid solar cells are advantageous for material weight reduction and are attracting attention as next-generation solar cells for small satellites.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.21 no.3
• /
• pp.62-72
• /
• 2022

In this study, a miniaturized GPS band(L₁ : 1.575 GHz) antenna that can be mounted on a small drone is proposed. The miniaturization was designed by applying the perturbation method based on the λ/4 microstrip antenna and lengthening the current path at the edge of the patch. The miniaturized antenna was fabricatred such that it could be attached to the surface of styrofoam(ε_r=1.06, t=10 mm) having a size of 10 mm × 9 mm × 10 mm (0.05 λ × 0.05 λ × 0.05 λ). The thickness and length of the feeding line and the spacing between short stubs were adjusted for impedance matching. S₁₁ was found to be -18.8 dB at the center frequency of the fabricated antenna, 1.575 GHz. The radiation pattern measurement results show that the maximum gain of E_θ is 1.87 dBi in 0 directions in the xz-plane, and that E_θ is an omnidirectional characteristic with an average gain of -1.7 dBi in the yz-plane. It was found that the antenna can be used as an ultra-small microstrip antenna, which can be mounted on a small dron for GPS, and is capable of preserving a reduction ratio of 98.8% as compared to a λ/2 microstrip patch antenna.

• Journal of the Korea Concrete Institute
• /
• v.21 no.4
• /
• pp.389-400
• /
• 2009

A compression lap splice can be calculated longer than a tension lap splice in high strength concrete according to current design codes. Including effects of transverse reinforcement, a compression splice becomes much longer than a tension splice. Effects of transverse reinforcement and bar size on strength and behavior of compression lap splice, which always exist in actual structures, have been investigated through experimental study of column tests with concrete strength of 40 and 60 MPa. The results of the tests with bar diameters of 22 and 29 mm show that there is no size effect of bar diameter on compression lap splice. Bond strength of small bar diameter may increase. However, large diameters of re-bars are used in compression member and the size effect of re-bars does not have to be considered in compression lap splice. Confined specimens have twice of calculated strengths by current design codes. New design equations for the compression lap splice including the effects of transverse reinforcement are required for practical purpose of ultra-high strength concrete. End bearing is enhanced by transverse reinforcement placed at ends of splice not by transverse reinforcement within splice length. As more transverse reinforcement are placed, the stresses developed by bond linearly increase. The transverse reinforcements at ends of splice a little improve the strength by bond. Because the stresses developed by bond in compression splice with transverse reinforcement are nearly identical to or less than those in tension splice with same transverse reinforcement, strength increment of compression splice is attributed to end bearing only.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2006.11a
• /
• pp.65-74
• /
• 2006

Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.20 no.7
• /
• pp.1296-1302
• /
• 2016

A hardware implementation of ultra-lightweight block cipher algorithm PRESENT that was specified as a block cipher standard for lightweight cryptography ISO/IEC 29192-2 is described in this paper. Two types of crypto-core that support master key size of 80-bit are designed, one is for encryption-only function, and the other is for encryption and decryption functions. The designed PR80 crypto-cores implement the basic cipher mode of operation ECB (electronic code book), and it can process consecutive blocks of plaintext/ciphertext without reloading master key. The PR80 crypto-cores were designed in soft IP with Verilog HDL, and they were verified using Virtex5 FPGA device. The synthesis results using $0.18{\mu}m$ CMOS cell library show that the encryption-only core has 2,990 GE and the encryption/decryption core has 3,687 GE, so they are very suitable for IoT security applications requiring small gate count. The estimated maximum clock frequency is 500 MHz for the encryption-only core and 444 MHz for the encryption/decryption core.

• Korean Journal of Materials Research
• /
• v.10 no.3
• /
• pp.223-226
• /
• 2000

The oxygen deficient ferrites $(Ni_x,\; Zn_{1-x})Fe_2O_{4-{\delta}}$ can decompose $CO_2$ as C and $O_2$ at a low temperature of about $300^{\circ}C$. Ultra powders of $(Ni_x,\; Zn_{1-x})Fe_2O_4$ for the $CO_2$ decomposition were prepared by the hydrothermal methods. The XRD result of synthesized ferries showed the spinel structure of ferrites and ICP-AES and EDS quantitative analyses showed the composition similar with the starting molar ratios of the mixed solution prior to reaction. The BET surface area of the synthesized(Ni, Zn)-ferrites was above $110\textrm{m}^2/g$ and its particle size was very as small as about 5~10 nm. The $CO_2$ decomposition efficiency of the oxygen deficient ferrites($(Ni_x,\;Zn_{1-x})Fe_2O_{4-{\delta}}$) was almost independent with composition and the $CO_2$ decomposition efficiency of ternary (Ni, Zn)-ferrites was better than of binary Ni-ferrites.

• Journal of IKEEE
• /
• v.22 no.3
• /
• pp.613-618
• /
• 2018

In this paper, an active snubber type flyback converter was applied to a 60W class adapter and its test results are reported by producing a prototype. Especially, the prototype of the adapter was designed for both input voltage of 110V and 220V. The output voltage was designed for 60W with 19V class which is the most commonly used in laptops. The prototype was designed to a volume of about $50cm^3$ and a power density of about $1.22W/cm^3$ to minimize the size and verify portability. The maximum efficiency of the prototype was 90.88% at its maximum load of 60W against input voltage change and 91.04% was observed at 60W under input voltage of 220V. Furthermore, the stability of the output voltage against load power was observed to be within about 0.07%.

• Journal of Sensor Science and Technology
• /
• v.30 no.5
• /
• pp.342-348
• /
• 2021

For the characterization or failure analysis of electronic devices such as PCB (printed circuit boards), the most common method is the measurement of voltage waveforms with an oscilloscope. However, because there are many types of problems that cannot be detected by voltage waveform analysis, several other methods such as X-ray transmission, infrared imaging, or eddy current measurement have been applied for these analyses. However, these methods have also been limited to general analyses because they are partially useful in detecting physical defects, such as disconnections or short circuits. Fundamentally current waveform measurements during the operation of electronic devices need to be performed, however, commercially available current sensors have not yet been developed, particularly for applications in highly integrated PCB products with sub-millimeter fine pitch. In this study, we developed a highly sensitive PHR (planar hall resistance) magnetic sensor for application in highly integrated PCBs. The developed magnetic sensor exhibited sufficient features of an ultra-small size of less than 340 ㎛, magnetic field resolution of 10 nT, and current resolution of 1 mA, which can be applicable for PCB analyses. In this work, we introduce the development process of the magnetic sensing probe and its characteristic results in detail, and aim to extend this pin-type current probe to applications such as current distribution imaging of PCBs.

• Korean Journal of Optics and Photonics
• /
• v.32 no.6
• /
• pp.259-265
• /
• 2021

Recently, lens manufacturing and assembly technology has greatly improved. However, tight requirements of manufacturing and assembly lead to an increase in cost and manufacturing time, and in some cases the performance of an optical system may deteriorate depending on the operating environment's conditions, such as temperature or vibration. In addition, the use of a compensator is an effective method to reduce sensitivity in an ultra-precision optical system, but in the case of a small lens, such as that in an endoscope, it is difficult to use a compensator due to the size limitation of the lens barrel. Therefore, minimizing lens sensitivity is the most important technology in lens design. For this reason, there have been various attempts to reduce the lens sensitivity, and there is a trend to add functions to reduce the sensitivity in the lens design S/W. In this paper, we introduce a design technology that minimizes lens sensitivity. We first design a lens with quite good performance, then analyze the sensitivity of this lens, make a multi-configuration with high-sensitivity element error, and then reoptimize it. We prove with an example that this design technique is very effective.