• 대한한의학회지
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• 제26권2호
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• pp.85-94
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• 2005

Objectives: This study was carried out to estimate the demand for clinical trials and contribute to the consolidation of function and role in the clinical trial centers of oriental medicine. Methods: A survey of the demand was made of 379 faculties of oriental medicine in 11 oriental medical colleges throughout the country using two?part investigations by e-mail questionnaire over 1 month. The final data from 56 faculties were analyzed. Results: Clinical trials of oriental medicine have been continuously increasing. Furthermore, the demand and necessity for clinical trials of oriental medicine have also been continuously enhanced. Although there were arguments for and against the establishment of a clinical trial center for oriental medicine, the demand and necessity for the establishment was the overall consensus. Concerning objections, a high intention of use was observed. Conclusions: These results imply that the demand for clinical trials will increase remarkably through the establishment of a clinical trial center for oriental medicine. Further study is needed about the demand for such a center.

• Clinics in Shoulder and Elbow
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• 제27권2호
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• pp.237-246
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• 2024

Proximal humeral fractures (PHFs) are a common injury among the older population. An ideal therapeutic protocol has yet to be developed, and numerous clinical trials are being conducted to find the best therapeutic approach. The purpose of this study is to evaluate the current body of knowledge available via interventional clinical trials. In December 2022, interventional clinical trials relating to PHFs on Clinicaltrials.gov were screened. Trial characteristics included duration, status, intervention, phase, outcomes, location, and study design. Publications associated with each trial were searched on PubMed/Medline using the ClinicalTrials.gov registry number. The final dataset comprised 64 trials. The most common trial status was completed (36%). The majority did not have a Food and Drug Administration-defined phase (67%), was randomized (81%), involved a single facility (72%), used a parallel assignment intervention model (80%), and used an open-label approach (45%). Eleven trials were associated with a publication, and the publication rate was 17%. Average enrollment was 86 participants, and mean trial duration was 51.4 months. Europe/UK/Russia/Turkey participated in the most trials (70%). Most of the trials were initiated after 2010 (87.5%). Procedure-related interventions (55%) were most common. Disability/function was the most common primary outcome assessed (61%). The low publication rate and the multitude of trials conducted after 2010 highlight the urgency and need for trial results to be published to establish an ideal therapeutic protocol. Since the majority of the trials involved a single institution and an open-label approach, reinforcing blinding and establishing multi-centered trials can improve the validity of the clinical trial results.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1984년도 학술대회지
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• pp.215-223
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• 1984

인삼이 노령자의 피로 및 쇠약 치료효과에 미치는 영향을 연구하기 위해 런던의 성프란시스병원과 지방의 일반 개업 병인으로부터 50명의 노인들을 모집하였다. 매일 2g의 홍삼 분말을 이중맹검법에 의하여 10일간 투약하였으며. 위약과 홍삼 분말의 투여는 3주간의 간격을 두고 각기 투여하였다. 간호원이 10가지 정신측정 종합테스트와 심리측정 테스트를 하였고, 기분상태 및 일반적인 건강평가를 설문지로 측정하였다 이 측정을 홍삼 및 위약의 투여기간을 전후하여 실시하였다. 즉, 각각의 테스트를 모두 4번 실시하였다. 심리측정 테스트와 정신측정 종합테스트 결과 홍삼의 투여는 위약과는 달리, 미약하나마 일관성있는 증가를 가져왔다. 그러나 기분상태 및 일반적인 건강 평가는 별 변화가 없었다. 결론적으로 인삼은 강장효과를 갖는다 할 수 있다. 노인병 치료를 평가함에 있어 시도방법 및 기간 등에 의하여 약효의 평가가 모호해지는 경우가 종종 있다. 보다 적절한 임상시험법에 대하여 토론하고자 한다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2018년도 춘계학술대회
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• pp.318-320
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• 2018

When a ship sails on sea, it may be influenced by the environmental disturbance such as wind, wave, sea surface temperature, etc. These affect on the ship's speed, fuel consumption, safety and operating performance. It is necessary to find the optimal weather route of a ship to avoid adverse weather conditions which can put the crews in serious danger or cause structural damage to the vessel, machinery, and equipment. This study introduced how to apply A* algorithm based on sea trial test data for determining the optimal ship routes. The path cost function was modelled as a function of minimum arrival time or minimum energy depending on the time of various environment conditions. The specially modelled path-cost function and the safety constraints were applied to the A* algorithm in order to find the optimal path of the ship. The comparison of ship performances estimated by real sea trial's path and estimated optimal route during the voyage of the ship was investigated. The result of this study can be used to create a schedule to ensure safe operation of the ship with short passage time or minimum energy. In addition, the result of this study can be integrated into an on-board decision supporting expert system and displayed in Electronic Chart Display and Information System (ECDIS) to provide all the useful information to ship master.

• Structural Engineering and Mechanics
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• 제14권6호
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• pp.713-732
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• 2002

A local radial point interpolation method (LRPIM) based on local residual formulation is presented and applied to solid mechanics in this paper. In LRPIM, the trial function is constructed by the radial point interpolation method (PIM) and establishes discrete equations through a local residual formulation, which can be carried out nodes by nodes. Therefore, element connectivity for trial function and background mesh for integration is not necessary. Radial PIM is used for interpolation so that singularity in polynomial PIM may be avoided. Essential boundary conditions can be imposed by a straightforward and effective manner due to its Delta properties. Moreover, the approximation quality of the radial PIM is evaluated by the surface fitting of given functions. Numerical performance for this LRPIM method is further studied through several numerical examples of solid mechanics.

• 보건의료산업학회지
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• 제10권3호
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• pp.75-84
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• 2016

Objectives : The aim of this study was to compare a treatment focusing on the physical function to an intervention focusing on a cognitive strategy in stroke patients which improves their performance skills of daily activities. Methods : This study design was a randomized control trial selecting 43 people with stroke patients. This study consisted of a control group, which received conventional occupational therapy focusing on physical function, and an experimental group which was trained to develop a cognitive strategy by themselves. Both groups each received 10 sessions of the treatment. This study compared the skills for performing daily activities before and after the intervention and analyzed the data with SPSS Ver. 18.0. Results : This study showed a significant improvement in all performance skills in the experimental group (p<.05). There was no statistically significant difference in the performance skills before and after the intervention in the control group (p>.05). Conclusions : It was verified that stroke patients to develop a cognitive strategy by themselves is more effective than to improve the physical function in performance skills for daily activities.

• 대한토목학회논문집
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• 제11권4호
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• pp.27-35
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• 1991

본 연구는 직선변이 단순지지, 원호변이 단순지지 및 고정지지 조건을 갖는 원통 panel을 해석하는 방법을 제시하였고 진동 및 좌굴에 관한 특성을 규명한 것이다. 초기응력을 받는 원통 panel을 지배하는 미분방정식은 Love-Timoshenko의 기초식을 이용하여 유도하였으며 이 미분방정식을 Galerkin 해석법을 이용하여 수치해석 하였다. 특히 고정 지지조건을 갖는 panel에 대해서는 시행함수로서 삼각함수로 구성되는 경우와 쌍곡선함수로 된 보의 고유함수로 구성되는 경우에 대하여 각각 해석하였으며 이들 시행함수가 수치해에 미치는 영향을 검토하였다. 수치해석의 결과로 곡률 parameter와 고유 진동수 및 임계 좌굴계수와의 관계를 검토하였다. 또한 진동 및 좌굴 모드를 도시하였다.

• 한국강구조학회 논문집
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• 제12권6호
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• pp.737-748
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• 2000

본 논문은 직선변이 단순지지, 원호변이 단순 또는 고정인 경계조건의 원통 Panel을 해석하였다. 해석방법은 Galerkin법을 사용하였고, 기초방정식은 Love-Timoshenko의 기초식을 이용한 진동 좌굴 및 동적문제에 관한 특성을 명확히 하였다. 특히, 고정지지를 포함한 Panel에 대해서는 시행함수로서 삼각함수만으로 나타나는 경우와 쌍곡선함수로 나타나는 보의 고유함수를 이용하여 해석하였으며 시행함수에 미치는 영향을 검토하였다.

• 한국전기전자재료학회논문지
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• 제28권1호
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• pp.64-68
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• 2015

In this paper, LED lighting system is realized by using Bluetooth wireless communications and smartphones. A bluetooth module with a lighting control function is manufactured by miniaturizing a development board of TI company and the volume of LED dimming system as a whole is reduced. And a trial product is materialized by designing a hardware composed of the manufactured bluetooth module, LED down light equipped with degree warm white and cool white, and 2-channel LED driver; and LED dimming software. The materialized trial product is controled in terms of the brightness and color temperature of LED light source using an application of a smartphone. The experiment showed that the users can easily control the intensity of illumination of LED light source by using the scroll bar of the applications of smartphones. In addition, the color temperatures of both warm white and cool white can be controlled, and when the color temperature of the trial product using the manufactured bluetooth module is compared with that of a trial product of TI company, they show the same color temperatures.

• Structural Engineering and Mechanics
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• 제29권3호
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• pp.289-300
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• 2008

The use of metric trial functions to represent the real stress field in what is called the unsymmetric finite element formulation is an effective way to improve predictions from distorted finite elements. This approach works surprisingly well because the use of parametric functions for the test functions satisfies the continuity conditions while the use of metric (Cartesian) shape functions for the trial functions attempts to ensure that the stress representation during finite element computation can retrieve in a best-fit manner, the actual variation of stress in the metric space. However, the issue of how to handle situations where there is locking along with mesh distortion has never been addressed. In this paper, we show that the use of a consistent definition of the constrained strain field in the metric space can ensure a lock-free solution even when there is mesh distortion. The three-noded Timoshenko beam element is used to illustrate the principles. Some significant conclusions are drawn regarding the optimal strategy for finite element modelling where distortion effects and field-consistency requirements have to be reconciled simultaneously.