• Title/Summary/Keyword: Traditional Chinese Medicines

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Traditional Medicine in Korea : The Past and the Present

  • Chung, See-Ryun;Lee, Seung-Ho;Jeune, Kyung-Hee;So, Myung-Suk
    • Natural Product Sciences
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    • v.9 no.4
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    • pp.205-209
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    • 2003
  • The Korean peninsula, located between the vast Chinese mainland and Japan, has a unique cultural background that goes back five thousand years. In ancient times, the region was deeply influenced by Chinese culture, and traditional medicine in Korea was no exception. The Korean character, HAN GUL (24 alphabets), was invented at in the early 1400s by The Great King Sejong (1397-1450) of the Chosun dynasty. But few changes were made to traditional medicines for about 500 years thereafter. At the start of the 20th century, missionaries from western countries introduced new concepts and techniques of medicine. During the last century, there was enormous development in modern medical sciences. Even today, however, natural medicine -including folk medicine (or traditional Chinese medicine) - plays an important role in Korean health care. In this paper, we will review and discuss traditional Korean medicines as it has evolved over the past three thousand years.

A review of allergic rhinitis in traditional Chinese medicine

  • Lee, Sang-Chang;Kim, Min-San;Seong, Man-Jun;Choi, Mi-Sun;Kang, Suk-Hoon;Lee, Sheng-Ho;Kim, Jong-Hak;Lee, Young-Seob;Kwon, Dong-Yeul
    • Journal of Evidence-Based Herbal Medicine
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    • v.1 no.2
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    • pp.27-33
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    • 2008
  • Allergic rhinitis comes within snuffle in Chinese medicine. For generations, physicians have believed that the internal factors that cause this disease are pulmonary tuberculosis, splenic hypofunction and loss of virility, and its external factors are a cold, an uncommon atmosphere and an uncommon flavor. From the viewpoint of Chinese medicine, this symptom was fundamentally cured by "abidance by individuality, locality and seasons", on the basis of demonstration. In result, visceral function was recovered. In Chinese medicine, a disease is etiologically cured by the principles of Wholism and by discriminating among symptoms. In particular, "method for replenishing Qi and securing Exterior" has been widely used among the foregoing therapeutics. According to modern pharmacology, Astragli Radix, Atractylodis Macrocephalae Rhizoma and Ledebouriellae Radix all have antihistaminic effects and strengthen of the masticating and swallowing function of the recticuloendothelial system. This disease can be cured by controlling immunity and allergic reactions. Besides, it is necessary to take moderate exercise, to strengthen constitution, to avoid causative substances, to control ingesting flesh, meat and shrimps, to eat little, and to avoid what is cold and raw.

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Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (V) (중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (V))

  • Lee, Yun-Mi;Kim, Young-Sook;Kim, Joo-Hwan;Kim, Jin-Sook
    • Korean Journal of Pharmacognosy
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    • v.42 no.2
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    • pp.187-194
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    • 2011
  • Aldose reductase (AR), the key enzyme in the polyol pathway, plays an important role in the development of the diabetic complications. None of Aldose reductase Inhibitor (ARI) has achieved worldwide use because of limited efficacy or undesirable side effects. Therefore, evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Fifty two Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, twelve herbal medicines, Artemisia anomala (aerial part), Centella asiatica (aerial part), Scutellaria baicalensis (root), Senecio chrysanthermoides (whole plant), Gleditsia japonica (twig), Zizyphus jujube (twig, leaf), Citrus aurantium (fruit), Hydnocarpus anthelmintica (fruit), Potaninia mongolica (aerial part), Tribulus terrestris (fruit), Artemisia apiacea (aerial part) and Eclipta prostrate (aerial part) exhibited a significant inhibitory activity against AR. Particularly, Artemisia anomala, Centella asiatica and Scutellaria baicalensis showed four times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

The Chemokine SDF-1α Suppresses Fibronectin-mediated In Vitro Lymphocytes Adhesion

  • Ji, LiLi;Sheng, YuChen;Wang, ZhengTao
    • Molecules and Cells
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    • v.22 no.3
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    • pp.308-313
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    • 2006
  • Stromal cell-derived factor (SDF-1) is a CXC chemokine that selectively activates the CXCR4 chemokine receptor. Fibronectin is an intracellular matrix component that binds integrin and mediates cell-matrix adhesion. Activation of the integrin receptor can occur in two ways: by ligand binding (outside-in signaling), and in response to intracellular events (inside-out signaling). In the current study we showed that SDF-$1{\alpha}$ inhibited adhesion of T lymphocyte Jurkat cells resulting from binding high concentrations of fibronectin as well as that of THP-1 monocytes. The effect of SDF-$1{\alpha}$ on fibronectin-mediated adhesion was partly reversed by the CXCR4 receptor antagonist T140. Our results suggest that an SDF-1/CXCR4 signal pathway modulates fibronectin-mediated lymphocytes adhesion.

Merging the old with the new: a cybermedicine marriage for oncology interactions with traditional herbal therapies and complementary medicines

  • Yap, Kevin Yi-Lwern;Lim, Ken Juin
    • CELLMED
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    • v.2 no.2
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    • pp.18.1-18.16
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    • 2012
  • An oncology-specific database called OncoRx (http://bit.ly/cancerRx) was previously set up in cyberspace to aid clinicians in identifying interactions of anticancer drugs (ACDs) and chemotherapy regimens with traditional Chinese medicines (TCMs) and complementary and alternative medicines (CAMs). Since then, users have requested the drug-CAM interactions (DCIs) of 5 specific CAMs (cranberry, melatonin, co-enzyme Q10, huachansu, reishi mushroom) to be updated in the database. Pharmacokinetic properties (metabolism, enzyme induction/inhibition, elimination), TCM properties and DCIs of each CAM were collated with 117 ACDs using 9 hardcopy compendia and online databases as resources. Additionally, individual ACDs and CAMs were used as keywords for PubMed searches in combination with the terms 'anticancer drugs', 'drug interactions', 'herb-drug/drug-herb interactions', 'pharmacokinetic interactions' and 'pharmacodynamic interactions'. DCI parameters consisted of interaction effects, evidence summaries, proposed management plans and alternative non-interacting CAMs, together with relevant citations and update dates of the DCIs. OncoRx is also used as a case to introduce the "Four Pharmaco-cybernetic Maxims" of quality, quantity, relationship and manner to developers of digital healthcare tools. Its role in Hayne's "5S" hierarchy of research evidence is also presented. OncoRx is meant to complement existing DCI resources for clinicians and alternative medicine practitioners as an additional drug information resource that provides evidence-based DCI information for ACD-CAM interactions.

Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (III) (중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (III))

  • Lee, Yun-Mi;Kim, Jong-Min;Kim, Young-Sook;Jang, Dae-Sik;Kim, Joo-Hwan;Bae, Ki-Hwan;Kim, Jin-Sook
    • Korean Journal of Pharmacognosy
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    • v.40 no.4
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    • pp.394-399
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    • 2009
  • Aldose reductase (AR) is a critical enzyme in the development of the diabetic complications. AR, the first enzyme in the polyol pathway, catalyzes the reduction of the aldehyde form of glucose to sorbitol with concomitant conversion of NADPH to $NADP^+$. None of aldose reductase inhibitor (ARI) has achieved worldwide use because of limited efficacy or undesirable side effects. Therefore, evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Forty eight Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, seven herbal medicines, Buddleja officinalis (whole plant), Lonicera japonica (leaf and flower), Polygonum aviculare (aerial part), Polygonum aviculare (whole plant), Salvia miltiorrhiza (root), Schisandra chinensis (stem), and Zanthoxylum armatum (leaf and stem) exhibited a significant inhibitory activity against AR. Particularly, L. japonica and P. aviculare showed two times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

'The investigation of frequently used only in China' (중국내(中國內)에 다용(多用)되고 한국(韓國)에서 소용(少用)되는 약재(藥材)에 관(關)한 고찰(考察))

  • Kim, Dong-Woo
    • The Journal of Korean Medicine
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    • v.18 no.2
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    • pp.326-339
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    • 1997
  • The Background and Purpose : Many herb-medicines are frequently used in China but they are not in Korea. It is required to prove them worthy to introduce into Korea and to find substitutes for them. The Objective and Methods : During stay in China as a Professor extraordinary, I investigated applications of Chinese modicines, books and theses. The Results and Conclusions : 1. In China the cheap herb-medicines are chosen preferentially and the classic rules of oriental medicine are truly observed. 2. in China it is impossible to prove virtue of ready made herb-medicines because constituents are not opened. 3. Commonly used herb-medicines are drug of clean away heat(淸熱藥) which are antinflammatories or anti-toxins. 4. Antitumorigenic effects was frequently reported but they don't get complete agreement also in China. 5. Herb-medicines which are frequently used in China but not in Korea have no significant differences from commonly used herb-medicines in Korea.

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The Comparative Study of Oriental Medicine in Korea, Japan and China (한국(韓國)과 일본(日本) 및 중국(中國)의 동양의학(東洋醫學)에 대한 비교연구(比較硏究))

  • Cho, Ki-Ho
    • The Journal of Korean Medicine
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    • v.19 no.1
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    • pp.271-298
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    • 1998
  • During these days of new understanding, western medicine has developed remarkably and a revaluation of traditional medicine has been achieved. This appears to have resulted from the sound criticisms of what western medicine has achieved up to now; excessive subdivisions of clinical medicine, severe toxicity of chemical drugs, lack of understanding about patients complaints which cannot be understood objectively, and etc. It is thought that the role of traditional medicine will be more important in the future than it is now. Someone said that the research methods of traditional medicine depends on the way of experimental science too much. That there was no consideration of a system for traditional medicine and the critic also went so far as to assert that in some cases the characteristics of eastern ideas is to permit irrationalism itself. In view of this thinking, the term traditional medicine seems to have been used somewhat too vaguely. However, traditional medicine is a medical treatment which has existed since before the appearance of modern medicine and it was formed from a traditional culture with a long history. One form of traditional medicine, oriental medicine based upon ancient Chinese medicine, was received in such countries as Korea, Japan, Thailand, Vietnam, Tibet, and Mongolia. Oriental medicine then developed in accordance with its own environment, race, national characteristics, and history. Although there are some simultaneous differences between them, three nations in Eastern Asia; Korea, Japan, and China, have especially similar features in their clinical prescriptions and medical literature. These three nations are trying to understand each others unique traditional medicines through numerous exchanges. Even though many differences in their ways of studying have developed over history exist, recent academic discussions have been made to explore new ways into oriental medicine. Therefore a comparative study of oriental medicine has gradually been thought to be more important. In Korea the formation of a new future-oriented paradigm for oriental medicine is being demanded. The purpose of the new paradigm is to create a new recognition of traditional culture which creates an understanding of oriental medicine to replace the diminished understanding of oriental medicine that was brought about by the self-denial of traditional culture in modem history and cultural collisions between oriental and occidental points of view. Therefore, to make a new paradigm for oriental medicine which is suitable for these days, and fortifies the merit of oriental medicine while compensating its defects, the author has compared the characteristics of oriental medicines in Korea, Japan, and China. The conclusions of this research are as follows: 1. The fundamental differences of the traditional medicines of these three nations are caused by the differences in the systems of Naekyung and Sanghannon. 2. The pattern-identification of illnesses is generally divided into two categories; the pattern identification of Zang-Fu and the pattern identification of prescription. 3. There are many differences in the definition of terms, such as Yin and Yang, Deficiency and Excess, and etc. 4. Chinese traditional medicine has some new concepts about pattern identification and epidemic febrile disease. 5. Japanese traditional medicine has some characteristics about pattern identification of the whole bodys condition and signs of abdominal palpation. 6. In terms of the effects of herbal drugs, Chinese traditional medicine attaches great importance to the experiential efficacy of the herb, and Japanese traditional medicine is taking a serious view of the effects of experimental medical actions.

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Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (IV) (중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (IV))

  • Lee, Yun-Mi;Kim, Young-Sook;Bae, Ki-Hwan;Kim, Joo-Hwan;Kim, Jin-Sook
    • Korean Journal of Pharmacognosy
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    • v.41 no.4
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    • pp.289-296
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    • 2010
  • Aldose reductase (AR), the principal enzyme of the polyol pathway, has been shown to play an important role in the development of the diabetic complications. Evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Sixty four Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, thirteen herbal medicines, Inula helianthus-aquatilis C. Y. Wu ex Ling. (whole plant), Erigeron breviscapus (Vant.) Hand. Mazz. (whole plant), Lonicera hypoglauca Miq. (leaf, stem), Scutellaria orthocalyx Hang. Mazz. (whole plant), Berchemia floribunda Brongn. (leaf, stem), Michelia alba DC. (flower), Oroxylum indicum (seed), Punica granatum L. (peel), Elsholtzia capituligera (whole plant), Trachelospermum jasminoides (Lindl.) Lem. (whole plant), Elsholtzia strobilifera Benth. (whole plant), Agrimonia pilosa var. nepalensis (D. Don) Nakai (whole plant) and Aster poliothamnus Diels (whole plant) exhibited a significant inhibitory activity against AR. Particularly, Inula helianthus-aquatilis C. Y. Wu ex Ling. showed seven times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

A Literature Survey of the Modern Techniques Used for the Processing of Herbal Medicines (한약재 포제 가공의 현대적 연구 현황)

  • Oh, Ju-Hee;Sin, Jae-Seok;Ahn, Eun-Seok;Lee, Seong-Jun;Lee, Jong-chul;Lim, Jun-hong;Hong, Sea-kap;Hong, Jun-ki;Lee, Young-Joo
    • Journal of Pharmaceutical Investigation
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    • v.39 no.4
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    • pp.275-297
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    • 2009
  • Herbal medicines have been used worldwide, particularly in the Far East countries, for thousands of years. Herbal medicines comprise complex mixtures of different phytochemical substances, and their nature may vary substantially depending on many factors related to the cultivation condition, area and harvest time. The processing of the herbal medicines significantly affects their pharmacological and toxicological properties. In this paper, we discuss current research that deals with the techniques for processing Chinese herbal medicines. These results will provide a scientific basis for developing new techniques for the processing of herbal medicines.