• Design Convergence Study
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• v.17 no.4
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• pp.17-29
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• 2018

In the semi-autonomous vehicle, before reaching a fully autonomous driving stage, it is imperative for the system to issue a take-over request(TOR) that asks a driver to operate manually in a specific situation. The purpose of this study is to compare whether head-up display(HUD) is a better human-vehicle interaction than head-down display(HUD) in the event of TOR. Upon recognition of TOR in the experiment with a driving simulator, participants were prompted to switch over to manual driving after performing a secondart task, that is, playing a game, while in auto-driving mode. The results show that HUD is superior to HDD in 'ease of use' and 'satisfaction' although there is no significant difference in reaction time and subjective workload. Therefore, designing secondary tasks through HUD during autonomous driving situation improves the user experience of the TOR function. The implication of this study lies in the establishing an empirical case for setting up UX design guidelines for autonomous driving context.

• Journal of the Korean Geographical Society
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• v.32
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• pp.11-23
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• 1985

• Bulletin of the Korean Mathematical Society
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• v.60 no.1
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• pp.23-32
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• 2023

Let 𝓢 be a Serre class in the category of modules and 𝖆 an ideal of a commutative Noetherian ring R. We study the containment of Tor modules, Koszul homology and local homology in 𝓢 from below. With these results at our disposal, by specializing the Serre class to be Noetherian or zero, a handful of conclusions on Noetherianness and vanishing of the foregoing homology theories are obtained. We also determine when Tor^R_𝓼+t(R/𝖆, X) ≅ Tor^R_𝓼(R/𝖆, H^𝖆_t(X)).

• Bulletin of the Korean Mathematical Society
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• v.52 no.2
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• pp.531-540
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• 2015

Let (R, m) be a Noetherian local ring, I an ideal of R, and A an Artinian R-module. Let $k{\geq}0$ be an integer and $r=Width_{>k}(I,A)$ the supremum of length of A-cosequence in dimension > k in I defined by Nhan-Hoang [8]. It is shown that for all $t{\leq}r$ the sets $$(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/I^n,A)))_{{\geq}k}\;and\\(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/(a_1^{n_1},{\cdots},a_l^{n_l}),A)))_{{\geq}k}$$ are independent of the choice of $n,n_1,{\cdots},n_l$ for any system of generators ($a_1,{\cdots},a_l$) of I.

• BMB Reports
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• v.50 no.9
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• pp.437-444
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• 2017

Different types of eukaryotic cells may adopt seemingly distinct modes of directional cell migration. However, several core aspects are regarded common whether the movement is either ameoboidal or mesenchymal. The region of cells facing the attractive signal is often termed leading edge where lamellipodial structures dominates and the other end of the cell called rear end is often mediating cytoskeletal F-actin contraction involving Myosin-II. Dynamic remodeling of cell-to-matrix adhesion involving integrin is also evident in many types of migrating cells. All these three aspects of cell migration are significantly affected by signaling networks of TorC2, TorC1, and PP2A/B56. Here we review the current views of the mechanistic understanding of these regulatory signaling networks and how these networks affect eukaryotic cell migration.

• Journal of Chest Surgery
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• v.51 no.3
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• pp.161-166
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• 2018

Patient-prosthesis mismatch (PPM) is a controversial issue in current clinical practice. PPM has been reported to have a negative impact on patients' prognosis after aortic valve replacement in several studies, showing increased all-cause and cardiac mortality. Moreover, a close relationship has recently been described between PPM and structural valve deterioration in biological prostheses. In patients at risk for PPM, several issues should be considered, and in the current era of cardiac surgery, preoperative planning should consider the different types of valves available and the various surgical techniques that can be used to prevent PPM. The present paper analyses the state of the art of the PPM issue.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2199-2205
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• 2016

Vibrio cholerae O1 serogroup Wave 3 El Tor strains are presently prevalent worldwide. The Wave 3 El Tor strains contain a TLC:RS1:CTX array on chromosome 1, and no element is integrated on chromosome 2. A multiplex PCR optimized to identify the TLC:RS1:CTX array of Wave 3 strains has been developed in this study. By using eight primers, the multiplex PCR can identify the characteristic CTX and RS1 array of Wave 3 strains from various arrays of strains belonging to other Waves. The four amplified DNA fragments of Wave 3 strains have been cloned in a vector, which could be used as a positive control for the multiplex PCR. This multiplex PCR and the positive control set could be useful tools for rapid recognition of Wave 3 El Tor strains.

• Journal of Microbiology and Biotechnology
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• v.23 no.7
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• pp.923-931
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• 2013

Rapamycin, known as an inhibitor of Target of Rapamycin (TOR), is an immunosuppressant drug used to prevent rejection in organ transplantation. Despite the close association of the TOR signaling cascade with various scopes of metabolism, it has not yet been thoroughly investigated at the metabolome level. In our current study, we applied mass spectrometric analysis for profiling primary metabolism in order to capture the responsive dynamics of the Chlamydomonas metabolome to the inhibition of TOR by rapamycin. Accordingly, we identified the impact of the rapamycin treatment at the level of metabolomic phenotypes that were clearly distinguished by multivariate statistical analysis. Pathway analysis pinpointed that inactivation of the TCA cycle was accompanied by the inhibition of cellular growth. Relative to the constant suppression of the TCA cycle, most amino acids were significantly increased in a time-dependent manner by longer exposure to rapamycin treatment, after an initial down-regulation at the early stage of exposure. Finally, we explored the isolation of the responsive metabolic factors into the rapamycin treatment and the culture duration, respectively.

• Journal of Communications and Networks
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• v.16 no.4
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• pp.415-420
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• 2014

Since the day the Internet became a common and reliable mechanism for communication and data transfer, security officers and enthusiasts rallied to enforce security standards on data transported over the globe. Whenever a user tries communicating with another recipient on the Internet, vital information is sent over different networks until the information is dropped, intercepted, or normally reaches the recipient. Critical information traversing networks is usually encrypted. In order to conceal the sender's identity, different implementations have proven successful - one of which is the invention of anonymous networks. This paper thoroughly investigates one of the most common and existing techniques used during data communication for avoiding traffic analysis as well as assuring data integrity - the onion router (TOR). The paper also scrupulously presents the benefits and drawbacks of TOR.

• Nutrition Research and Practice
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• v.3 no.1
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• pp.64-71
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• 2009

Amino acids are fundamental nutrients for protein synthesis and cell growth (increase in cell size). Recently, many compelling evidences have shown that the level of amino acids is sensed by extra- or intra-cellular amino acids sensor(s) and regulates protein synthesis/degradation. Mammalian target of rapamycin complex 1 (mTORC1) is placed in a central position in cell growth regulation and dysregulation of mTOR signaling pathway has been implicated in many serious human diseases including cancer, diabetes, and tissue hypertrophy. Although amino acids are the most potent activator of mTORC1, how amino acids activate mTOR signaling pathway is still largely unknown. This is partly because of the diversity of amino acids themselves including structure and metabolism. In this review, current proposed amino acid sensing mechanisms to regulate mTORC1 and the evidences pro/against the proposed models are discussed.