• 대한정형외과스포츠의학회지
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• 제1권1호
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• pp.37-42
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• 2002

목적: 재건술의적응이되지않는전,후방십자인대손상환자에서radiofrequency 방식을이용한열위축술을시행하여술기및단기추시결과를보고하고자한다. 대상및방법 : 재건술의적응이되지않는전방십자인대9예, 후방십자인대5예를대상으로하였으며평균추시기간은6개월이었다. 결과 : 일상생활에서느꼈던불안정성은감소됐으며파행이나통증등이현저하게호전되었다. 다만후방십자인대에서시행한경우시간이지남에따라다시슬관절이완이증가하는소견을관찰할수있었다. 결론 : Radiofrequency를이용한열위축술은많은활동을요하는젊은사람의슬관절십자인대손상에서, 특히경도의부분파열및수술의적응이되지않는이완환자에서증상을보일경우시도해볼수있는술식중의하나로추천할만하다. 그러나본결과는단기추시이므로장기추시와대조군연구가요할것으로사료된다.

• International Journal of Computer Science & Network Security
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• 제23권2호
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• pp.183-192
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• 2023

Radiofrequency ablation (RFA) is an alternative treatment for liver cancer to the surgical intervention preferred by surgeons. However, the main challenge remains the use of RF for the ablation of large tumours (i.e., tumours with a diameter of >3 cm). For large tumours, RFA takes a large duration in the ablation process compared with surgery, which increases patient pain. Therefore, RFA for large tumours is not preferred by surgeons. The currently materials used in RF electrodes, such as the nickeltitanium alloy (nitinol), are characterized by low thermal and electrical conductivities. On the other hand, the use of materials that have high thermal and electrical conductivities, such as titanium aluminide alloy (gamma titanium), produces more thermal energy for tumours. In this paper, we developed a cool-tip RF electrode model that uses nickel-titanium alloy and replaced it with titanium aluminide alloy by using the finite element model (FEM). The aim of this paper is to study the effect of the thermal and electrical conductivities of gamma titanium on the ablation volume. Results showed that the proposed design of the electrode increased the ablation rate by 1 cm³ /minute and 6.3 cm³/10 minutes, with a decrease in the required time ablation. Finally, the proposed model reduces the ablation time and damages healthy tissue while increasing the ablation volume from 22.5% cm³ to 62.5% cm³ in ten minutes compared to recent studies.

• The Korean Journal of Pain
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• 제20권2호
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• pp.163-168
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• 2007

Background: Temporomandibular joint disorder (TMD) is a group of musculoskeletal conditions characterized by pain in the pre-auricular area, limitation of jaw movement and palpable muscle tenderness. Thermography is a nonionizing, noninvasive diagnostic alternative for the evaluation of TMD. This study was conducted to evaluate the usefulness of thermography in the assessment of TMD. Methods: Thermography was conducted on the 61 patients who had been diagnosed with TMD, and on the 34 normal symptom-free volunteers. The temperature differences between opposite sides of the temporomandibular joint (${\Delta}T_{TMJ}$) and the masseter muscle (${\Delta}T_{MST}$) were calculated. The sensitivity and specificity of thermography was calculated at the cut off values of 0.2, 0.3, and $0.4^{\circ}C$. Results: In the patient group, the ${\Delta}T_{TMJ}$ was $0.42{\pm}0.38^{\circ}C$ and the ${\Delta}T_{MST}$ was $0.38{\pm}0.33^{\circ}C$, whereas in the control group the ${\Delta}T_{TMJ}$ was $0.10{\pm}0.07^{\circ}C$ and the ${\Delta}T_{MST}\;0.15{\pm}0.10^{\circ}C$. In addition, the patient group demonstrated a significantly lower level of thermal symmetry than the control group (P < 0.001) in both the temporomandibular joints and the masseter muscles. The sensitivity of thermography at the cut off values of 0.2, 0.3 and $0.4^{\circ}C$ was 67.2, 49.2, and 42.6% in the temporomandibular joint (TMJ) and 60.7, 49.2 and 37.7% in the masseter muscle, respectively. The specificity of thermography at the cut off values of 0.2, 0.3 and $0.4^{\circ}C$ was 88.2, 100, and 100% in the TMJ and 61.8, 91.2 and 100% in the masseter muscles, respectively. The accuracy of thermography at the cut off values of 0.2, 0.3 and $0.4^{\circ}C$ was 74.7, 67.4, and 63.2% in TMJ and 61.1, 64.2 and 60.0% in the masseter muscles, respectively. Conclusions: Temperature differences exist between the opposite sides of the TMD and masseter muscles in patients with TMD. Although the sensitivity of thermography in the diagnosis of TMD is low, it has high specificity in the evaluation of TMD, and is therefore applicable to patients with TMD.

• 생약학회지
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• 제50권4호
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• pp.272-276
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• 2019

Corylopsis gotoana has been widely used as a traditional medicine for the treatment of lots of disease including cold, edema and vomiting. However pharmacological and phytochemical studies on the C. gotoana are extremely limited. Here in this study, the author investigated the anti-nociceptive effects of the methanolic extract of Corylopsis gotoana (MCG) using various pain models. In the present study, MCG exhibited strong and dose-dependent anti-nociceptive activities on various experimental pain models including thermal nociception and chemical nociception, compared to positive control such as tramadol and indomethacin. In addition, the result from combination test using naloxone, analgesic activity of MCG was slightly reduced, indicating that MCG acts as a partial opioid receptor agonist. These results demonstrated that MCG has potent analgesic potential and thus it may be possibly used as a valuable anti-nociceptive agent.

• Journal of Acupuncture Research
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• 제21권1호
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• pp.51-58
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• 2004

Objective: The purpose of this study is to report that D.I.T.I. can be used for diagnosis of scoliosis. Methods: We measured the posterior trunk surface of the patients with shoulder pain or low back pain. They were ruled out as scoliosis by D.I.T.I. and compared with X-ray finding of T L-spine Ap views and calculated scoliosis angle. Results: In according to the spinoprocess curve in D.I.T.I. we could rule out as scoliosis. Thermal difference of left and right segmental areas of the patients was showed. Scoliosis angle of the patients ranged from $4^{\circ}$ to $11^{\circ}$ in X-ray finding. Conclusions: The results suggest that D.I.T.I. can explain physiologic and functional abnormalities than X-ray, in diagnosis of scoliosis. But further studies are required to for the diagnosis of scoliosis by analysing D.I.T.I..

• Journal of Acupuncture Research
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• 제23권1호
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• pp.155-164
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• 2006

Objectives : The aim of this study is to validate the correlation between Assessment Instruments of Knee OA and digital infrared thermographic imaging(DITI) and to find out the methods to assess knee OA by DITI. Methods : 60 subjects were evaluated. They were asked to answer VAS pain scale, WOMAC, KHAQ and LFI. Correlation was assessed by examining the spearman's rank correlation coefficients. Results : VAS, WOMAC and LFI was correlated with not only the thermal difference between Ant. knee and Post. knee, but also the lowest temperature of Ant. knee. Conclusion: DITI value was useful for evaluating the degree of OA. And we should find out that decrease of pain is correlated with change of DITI value.

• Natural Product Sciences
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• 제18권4호
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• pp.215-220
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• 2012

The stem of Lindera obtusiloba (Lauraceae), has been widely used as a traditional medicine for the treatment of abdominal pain, bruise and hepatocirrhosis. In the present study, antinociceptive and sedative properties of the methanol extract of L. obtusiloba (MLO) were evaluated. MLO demonstrated strong and dose-dependent antinociceptive activities on various experimental pain models including thermal nociception and chemical nociception, compared to tramadol and indomethacin, reference drugs. In combination test using naloxone, the diminished analgesic activity of MLO was observed, indicating the relation with opioid receptor. Moreover, MLO also decreases pentobarbital-induced sleep latency and increases sleeping time suggesting its hypnotic and sedative action. The present results indicate that MLO could be used as valuable antinociceptive and sedative agent for the treatment of various diseases.

• 동의생리병리학회지
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• 제18권1호
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• pp.226-229
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• 2004

We investigated the comparative effect with different frequency and duration time of electroacupuncture(EA) for suppression of pain. Inflammation was induced by an intraplantar injection of 1 % carrageenan into the right hind paw. Bilateral EA stimulation with 2 Hz, 15 Hz and 120 Hz were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles in carrageenan-injected rats. The paw and tail thermal hyperalgesia were measured in 30-minute intervals after carrageenan injection using hot plate and tail flick analgesia meter, respectively. The significant difference was found between the control and any of EA frequencies examined. Especially 2 Hz EA presented more effective inhibitory effects compared with other frequency of EA in tail flick latency. The hyperalgesia induced by carrageenan was strongly inhibited by 2 Hz EA from 5 min post and reached sufficient effects from 20 min post EA treatment. These results suggest that EA treatment might be a useful therapy for mitigation of inflammatory pain.

• 대한한방체열의학회지
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• 제5권1호
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• pp.21-30
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• 2006

Objectives: The aim of this syudy is to validate the between Assessment Instruments of Knee OA and digital infrared thermographic imaging(DITI) and to find out the methods to assess knee OA by DITI. Methods: 60 subjects were evaluated. They were asked to answer VAS pain scale, WOMAC, KHAQ and LFI. Correlation was assessed by examining the spearman's rank correlation coefficients. Results: VAS, WOMAC and LFI was correlated with not only the thermal difference between Ant. knee and Post. knee, but also the lowest temperature of Ant. knee. Conclusion: DITI value was useful for evaluating the degree of OA. And we should find out that decrease of pain is correlated with change of DITI value.

• 대한정형외과스포츠의학회지
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• 제4권1호
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• pp.36-42
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• 2005

목적: 야구 선수에서 발생한 견관절 내부 후방 충돌에 대해 관절경 소견 및 치료 결과를 알아보고자 하였다. 대상 및 방법: 내부 후방 충돌로 진단하였던 5예를 대상으로 평균 15개월 추시하였다. 전 예에서 후기 거상기에 견관절 후방에 동통을 호소하였고, 외전 $120^{\circ}$에서 과수평-외전을 추가한 재위 검사상 전 예에서 양성을 보였다. 관절경하에 파열된 후방 관절와 순이나 SLAP 병변은 봉합하였고 회전근 개는 변연 절제하였으며 전방 관절낭 인대는 3예에서 관절낭 중첩술, 2예에서 관절낭 열 수축술을 시행하였다. 결과는 동통, 운동 범위, 운동 복귀 수준 등을 조사하였다. 결과: 관절경 소견상 전 예에서 후상방 관절와 순의 fraying이 있었고 2예에서는 후상방 관절와 순의 flap 파열, 1예에서는 제2형 SLAP 병변이 동반되었다. 전 예에서 극상근 건에 fraying이 관찰되었고 1예에서는 부분 파열을 보였다. 또한 전 예에서 $90^{\circ}{\sim}120^{\circ}$ 외전 및 외회전 상태에서 관절와 순에 회전근 개가 충돌하는 현상을 관찰할 수 있었다. 결과는 투구 시 전 예에서 동통이나 불안감은 없었으며, 평균 활동력은 이환 전의 활동력에 비해 평균 88% ($80{\sim}100%$)로 회복되었다. 결론: 내부 후방 충돌의 확진은 관절경 검사를 통해 가능할 것으로 사료되었으며, 내부 충돌의 원인이 되는 전방 미세 불안정성과 후방 관절낭 구축에 대해 전방 관절낭 중첩술이나 수축술 및 후방 관절낭 신연 운동은 비교적 만족스러운 결과를 보였다.