Browse > Article

Comparative Studies of the Electroacupuncture with Different Frequency and Duration Time in the Carrageenan-injected Rats  

Choi Byung Tae (Department of Anatomy, College of Oriental Medicine, Dongeui University)
Choi Yung Hyun (Department of Biochemistry, College of Oriental Medicine, Dongeui University)
Lee Yang Tae (Department of Physiology, College of Oriental Medicine, Research Institute of Oriental Medicine, Dongeui University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.1, 2004 , pp. 226-229 More about this Journal
Abstract
We investigated the comparative effect with different frequency and duration time of electroacupuncture(EA) for suppression of pain. Inflammation was induced by an intraplantar injection of 1 % carrageenan into the right hind paw. Bilateral EA stimulation with 2 Hz, 15 Hz and 120 Hz were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles in carrageenan-injected rats. The paw and tail thermal hyperalgesia were measured in 30-minute intervals after carrageenan injection using hot plate and tail flick analgesia meter, respectively. The significant difference was found between the control and any of EA frequencies examined. Especially 2 Hz EA presented more effective inhibitory effects compared with other frequency of EA in tail flick latency. The hyperalgesia induced by carrageenan was strongly inhibited by 2 Hz EA from 5 min post and reached sufficient effects from 20 min post EA treatment. These results suggest that EA treatment might be a useful therapy for mitigation of inflammatory pain.
Keywords
Electroacupuncture; carrageenan; frequency; duration time;
Citations & Related Records
연도 인용수 순위
  • Reference
1 The induction of pain: an integrative review /
[ Millan, M.J. ] / Prog. Neurobiol.   DOI
2 OFQ reverses the k opioidreceptor-mediated depression of calcium current in rat dorsal root ganglion neurons /
[ Zhang, M.;Sun, Q.;Wan, Y.;Yao, L.;Yu, Y.;Han, J.S. ] / NeuroReport   DOI
3 Changes in the content of immunoreactive dynorphin in dorsal and ventral spinal cord of the rat in three different conditions /
[ Xue, J.C.;Yu, Y.X.;Han, J.S. ] / Int. J. Neurosci.   DOI
4 Comparison of the antinociceptive effects induced by electroacupuncture and transcutaneous electrical nerve stimulation in the rat /
[ Wang, J.Q.;Mao, L.;Han, J.S. ] / Int. J. Neurosci.   DOI
5 Nociception, pain, and antinociception: current concepts /
[ Riedel, W.;Neeck, G. ] / Z. Rheumatol.   DOI
6 Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production /
[ Zhang, Y.;Shaffer, A.;Portanova, J.;Seibert, K.;Isakson, P.C. ] / J. Pharmacol. Exp. Ther.
7 Evaluation of the anti-inflammatory, anti-nociceptive and gastric effects of Ginkgo biloba in the rat /
[ Abdel-Salam, O.M.;Baiuomy, A.R.;El-batran, S.;Arbid, M.S. ] / Pharmacol. Res.   DOI
8 The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord /
[ Ebersberger, A.;Grubb, B.D.;Willingale, H.L.;Gardiner, N.J.;Nebe, J.;Schaible, H.G. ] / Neuroscience   DOI
9 Analgesia induced by electroacupunc- ture of different frequencies is mediated by different types of opioid receptors: another cross-tolerance study /
[ Chen, X.H.;Han, J.S. ] / Behav. Brain Res.   DOI
10 Central neurotransmitters and acupuncture analgesia /
[ Han, J.S.;Tang, J.;Ren, M.F.;Zhou, Z.F.;Fan, S.G.;Qiu, X.C. ] / Am. J. Chin. Med.   DOI
11 Mapping of prostaglandin E2 binding sites in rat brain using quantitative autoradiography /
[ Matsumura, K.;Watanabe, Y.;Imai-Matsumura, K.;Connolly, M.;Koyama, Y.;Onoe, H.;Watanabe. Y. ] / Brain Res.   DOI
12 C-fos proteins are not involved in the activation of preproenkephalin gene expression in rat brain by peripheral electric stimulation /
[ Guo, H.F.;Cui, X.;Hou, Y.;Tian, J.;Wang, X.;Han, J.S. ] / Neurosci. Lett.   DOI
13 Endomorphin and mu-opioid receptors in mouse brain mediate the analgesic effect induced by 2 Hz but not 100 Hz electro- acupuncture stimulation /
[ Huang, C.;Wang, Y.;Chang, J.K.;Han, J.S. ] / Neurosci. Lett.   DOI
14 Efferent functions of C-fiber nociceptors /
[ Sann, H.;Pierau, F.K. ] / Z. Rheumatol.   DOI
15 Is there more than one prostaglandin E receptor subtype mediating hyperalgesia in the rat hindpaw? /
[ Khasar, S.G.;Ouseph, A.K.;Chou, B.;Ho, T.;Green, P.G.;Levine, J.D. ] / Neuroscience   DOI
16 Analgesia induced by electroacupuncture of different frequencies is mediated by different types of opioid receptors: another cross-tolerance study /
[ Chen, X.H.;Han, J.S. ] / Behav. Brain Res.   DOI