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Organic solvent exposure for the chronic kidney disease: updated systematic review with meta-analysis

  • Chaeseong Lim;Hyeoncheol Oh
    • Annals of Occupational and Environmental Medicine
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    • v.35
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    • pp.11.1-11.17
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    • 2023
  • Background: Studies on the relationship between organic solvent exposure and chronic kidney disease (CKD) have presented inconsistent results. Definition of CKD has changed in 2012, and other cohort studies have been newly published. Therefore, this study aimed to newly confirm the relationship between organic solvent exposure and CKD through an updated meta-analysis including additional studies. Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The search was conducted on January 2, 2023 using Embase and MEDLINE databases. Case-control and cohort studies on the relationship between organic solvent exposure and CKD were included. Two authors independently reviewed full-text. Results: Of 5,109 studies identified, a total of 19 studies (control studies: 14 and cohort studies: 5) were finally included in our meta-analysis. The pooled risk of CKD in the organic solvent exposed group was 2.44 (1.72-3.47). The risk of a low-level exposure group was 1.07 (0.77-1.49). The total risk of a high-level exposure group was 2.44 (1.19-5.00). The risk of glomerulonephritis was 2.69 (1.18-6.11). The risk was 1.46 (1.29-1.64) for worsening of renal function. The pooled risk was 2.41 (1.57-3.70) in case-control studies and 2.51 (1.34-4.70) in cohort studies. The risk of subgroup classified as 'good' by the Newcastle Ottawa scale score was 1.93 (1.43-2.61). Conclusions: This study confirmed that the risk of CKD was significantly increased in workers exposed to mixed organic solvents. Further research is needed to determine the exact mechanisms and thresholds. Surveillance for kidney damage in the group exposed to high levels of organic solvents should be conducted.

Application Design for Food Allergy Management (식품 알레르기 관리에 관한 애플리케이션 설계)

  • Ji-Uk Han;Nam-Bin Kim;Ye-Won Lee;Byeong-Seung Yang;Won-Whoi Huh
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.24 no.2
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    • pp.197-203
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    • 2024
  • Food allergies are common and accidents occur annually. However, many people lack knowledge of the severity of allergies and food ingredients. Allergy-related applications currently on the market have problems such as providing information by relying only on certain certified products, food ingredients, and barcodes. This design plans a customized service application for food allergy patients. In this application, after extracting the text of the image using OCR technology, the food ingredients were read and displayed in large letters. In addition, if the user selects an ingredient that cannot be consumed through filtering technology, the restricted food is quickly and conveniently shown when searching for food ingredients. Finally, when scanning a barcode or searching for a product, food ingredient information is provided through barcode scanning and search engine technology that provides ingredient information of the product. Therefore, the purpose of this paper is to design an app in which users with food allergies can easily check food ingredients and avoid allergic reactions using databases and various information search methods.

Impact of dental imaging on pregnant women and recommendations for fetal radiation safety: A systematic review

  • Thiago Oliveira Gamba;Fernanda Visioli;Deise Renata Bringmann;Pantelis Varvaki Rados;Heraldo Luis Dias da Silveira;Isadora Luana Flores
    • Imaging Science in Dentistry
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    • v.54 no.1
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    • pp.1-11
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    • 2024
  • Purpose: This study was conducted to investigate the safety of dental imaging in pregnant women with respect to fetal health. Materials and Methods: Searches were conducted of the PubMed, Scopus, and Web of Science databases in May 2023. The inclusion criteria encompassed cross-sectional and longitudinal studies that focused on the analysis of diagnostic dental imaging in pregnant women, as well as studies utilizing phantoms to simulate imaging examinations. The exclusion criteria consisted of reviews, letters to the editor, book chapters, and abstracts from scientific conferences and seminars. Results: A total of 3,913 articles were identified. Based on a review of the titles and abstracts, 3,892 articles were excluded, leaving 21 articles remaining for full-text review. Of these, 18 were excluded, and 4 additional articles were included as cross-references. Ultimately, 7 articles underwent quantitative-qualitative analysis. Three retrospective studies were focused on pregnant women who underwent dental imaging procedures. The remaining 4 studies utilized female phantoms to simulate imaging examinations and represent the radiation doses absorbed by the uterus or thyroid. Conclusion: Few dental radiology studies have been conducted to determine the safe radiation threshold for pregnant women. Additionally, the reviewed articles did not provide numbers of dental examinations, by type, corresponding to this dose. Dental imaging examinations of pregnant women should not be restricted if clinically indicated. Ultimately, practitioners must be able to justify the examination and should adhere to the "as low as diagnostically acceptable, being indication-oriented and patient-specific" (ALADAIP) principle of radioprotection.

Recent Domestic and International Clinical Research Trends in Gua Sha Therapy: A Scoping Review (괄사요법의 국내외 최신 임상 연구 동향: 주제범위 문헌고찰)

  • Seungwon Jung;Seungkwan Choi;Jungho Jo;Yunhee Han;Hyeonjun Woo;Byeonghyeon Jeon;Wonbae Ha;Junghan Lee
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.1
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    • pp.23-38
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    • 2024
  • Objectives This study examined recent domestic and international clinical research trends in Gua sha therapy to suggest future direction for research. Methods We used six domestic and international databases (Research Information Sharing Service, Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, PubMed, Embase, Cochrane Library) to select clinical studies with an original text in English or Korean published after 2018. Results Finally, 55 studies were selected. Randomized controlled trials accounted for the largest amount with 42 studies. Instrument assisted soft tissue mobilization was the most frequent term referring to Gua sha. Muscle shortening, limited range of motion, and plantar fasciitis were the most common symptoms, with six cases each. Additionally, there were two studies targeting symptoms other than the musculoskeletal system. Conclusions Additional research is needed on the effects of Gua sha therapy on the back of the lower extremities and hip joints, and research is needed on the possibility of their clinical use for diseases or symptoms other than those of the musculoskeletal system. And standards for the terminology of Gua sha and the types and methods of applied interventions are needed.

The Role of Pharmacists' Interventions in Increasing Medication Adherence of Patients With Epilepsy: A Scoping Review

  • Iin Ernawati;Nanang Munif Yasin;Ismail Setyopranoto;Zullies Ikawati
    • Journal of Preventive Medicine and Public Health
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    • v.57 no.3
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    • pp.212-222
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    • 2024
  • Objectives: Epilepsy is a chronic disease that requires long-term treatment and intervention from health workers. Medication adherence is a factor that influences the success of therapy for patients with epilepsy. Therefore, this study aimed to analyze the role of pharmacists in improving the clinical outcomes of epilepsy patients, focusing on medication adherence. Methods: A scoping literature search was conducted through the ScienceDirect, PubMed, and Google Scholar databases. The literature search included all original articles published in English until August 2023 for which the full text was available. This scoping review was carried out by a team consisting of pharmacists and neurologists following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews and the Joanna Briggs Institute guidelines, including 5 steps: identifying research questions, finding relevant articles, selecting articles, presenting data, and compiling the results. Results: The literature search yielded 10 studies that discussed pharmacist interventions for patients with epilepsy. Five articles described educational interventions involving drug-related counseling with pharmacists. Two articles focused on similar pharmacist interventions through patient education, both verbal and written. Three articles discussed an epilepsy review service, a multidisciplinary intervention program involving pharmacists and other health workers, and a mixed intervention combining education and training with therapy-based behavioral interventions. Conclusions: Pharmacist interventions have been shown to be effective in improving medication adherence in patients with epilepsy. Furthermore, these interventions play a crucial role in improving other therapeutic outcomes, including patients' knowledge of self-management, perceptions of illness, the efficacy of antiepileptic drugs in controlling seizures, and overall quality of life.

A Survey on the Latest Research Trends in Retrieval-Augmented Generation (검색 증강 생성(RAG) 기술의 최신 연구 동향에 대한 조사)

  • Eunbin Lee;Ho Bae
    • The Transactions of the Korea Information Processing Society
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    • v.13 no.9
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    • pp.429-436
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    • 2024
  • As Large Language Models (LLMs) continue to advance, effectively harnessing their potential has become increasingly important. LLMs, trained on vast datasets, are capable of generating text across a wide range of topics, making them useful in applications such as content creation, machine translation, and chatbots. However, they often face challenges in generalization due to gaps in specific or specialized knowledge, and updating these models with the latest information post-training remains a significant hurdle. To address these issues, Retrieval-Augmented Generation (RAG) models have been introduced. These models enhance response generation by retrieving information from continuously updated external databases, thereby reducing the hallucination phenomenon often seen in LLMs while improving efficiency and accuracy. This paper presents the foundational architecture of RAG, reviews recent research trends aimed at enhancing the retrieval capabilities of LLMs through RAG, and discusses evaluation techniques. Additionally, it explores performance optimization and real-world applications of RAG in various industries. Through this analysis, the paper aims to propose future research directions for the continued development of RAG models.

Analysis of Literatures Related to Crop Growth and Yield of Onion and Garlic Using Text-mining Approaches for Develop Productivity Prediction Models (양파·마늘 생산성 예측 모델 개발을 위한 텍스트마이닝 기법 활용 생육 및 수량 관련 문헌 분석)

  • Kim, Jin-Hee;Kim, Dae-Jun;Seo, Bo-Hun;Kim, Kwang Soo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.23 no.4
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    • pp.374-390
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    • 2021
  • Growth and yield of field vegetable crops would be affected by climate conditions, which cause a relatively large fluctuation in crop production and consumer price over years. The yield prediction system for these crops would support decision-making on policies to manage supply and demands. The objectives of this study were to compile literatures related to onion and garlic and to perform data-mining analysis, which would shed lights on the development of crop models for these major field vegetable crops in Korea. The literatures on crop growth and yield were collected from the databases operated by Research Information Sharing Service, National Science & Technology Information Service and SCOPUS. The keywords were chosen to retrieve research outcomes related to crop growth and yield of onion and garlic. These literatures were analyzed using text mining approaches including word cloud and semantic networks. It was found that the number of publications was considerably less for the field vegetable crops compared with rice. Still, specific patterns between previous research outcomes were identified using the text mining methods. For example, climate change and remote sensing were major topics of interest for growth and yield of onion and garlic. The impact of temperature and irrigation on crop growth was also assessed in the previous studies. It was also found that yield of onion and garlic would be affected by both environment and crop management conditions including sowing time, variety, seed treatment method, irrigation interval, fertilization amount and fertilizer composition. For meteorological conditions, temperature, precipitation, solar radiation and humidity were found to be the major factors in the literatures. These indicate that crop models need to take into account both environmental and crop management practices for reliable prediction of crop yield.

A Study on System Requirements for Integrated Electronic Document Management System (IEDMS) (통합전자문서체계구현을 위한 요구기능 분석 연구 -A사의 전자문서관리 사례를 중심으로-)

  • 권택문
    • Journal of Information Technology Application
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    • v.2 no.1
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    • pp.55-81
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    • 2000
  • An Electronic Document Management System(EDMS) is an electronic system solution that is used to create, capture, distribute, edit, store and manage documents and related structured data repositories throughout an organization. Recently, documents of any type, such as text, images, and video files, and structured databases can be controlled and managed by an office automation system and an EDMS. Thus, many organizations are already using these information technologies to reduce process cycle-times. But what the organizations are missing is a integrated system the current workflow or office automation system and provides immediate access to and automatic routing of the organization's mission-critical information. This study tried to find out the user's requirements for integrating current information system and relatively new technology, electronic document management system in order to improve business operations, productivity and quality, and reduces waste. integration of electronic document management system(EDMS) and office automation system and proper use of these technological will improve organization's processes, and compress the process cycle-times. For this study a case study was done by a project team in cooperation with a government organization(say A company). Through this case study valuable electronic document management and office automation system requirement have been identified and reported for providing a system model in order to design an Integrated EDMS(IMDMS).

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Systemic review: Herbal Medicines in the Treatment of Osteoarthritis in Pubmed and Chinese Medical Journals (퇴행성관절염(退行性關節炎) 한방치료(韓方治療)에 대(對)한 최근(最新) 연구(硏究) 동향(動向) - 임상연구(臨床硏究) 방법론(方法論)을 중심(中心)으로 -)

  • Seo, Byung-kwan;Ryu, Seong-ryong;Lee, Song-shil;Huh, Jeong-eun;Baek, Yong-hyeon;Lee, Jae-dong;Choi, Do-young;Cho, Yoon-je;Kim, Nam-jae;Park, Dong-suk
    • Journal of Acupuncture Research
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    • v.21 no.3
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    • pp.265-282
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    • 2004
  • Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed. Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

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A Study on the Cloud Service Model of CaaS Based on the Object Identification, ePosition, with a Structured Form of Texts (문자열로 구조화된 사물식별아이디 이포지션(ePosition) 기반의 클라우드 CaaS(Contents as a Service) 서비스 모델에 관한 연구)

  • Lee, Sang-Zee;Kang, Myung-Su;Cho, Won-Hee
    • Information Systems Review
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    • v.15 no.3
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    • pp.129-139
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    • 2013
  • The Internet of Things (or IoT for short) which refers to uniquely identifiable objects and their virtual representations in an Internet-like structure is to be reality today. The amount of data on IoT is expected to increase abruptly and there are several key issues like usefulness interoperability between multiple distributes systems, services and databases. In this paper a methodology is proposed to realize a recently developed cloud service model, Contents as a Service (CaaS), which is contents delivery model referred to as 'on-demand contents'. In the proposed method, the global object identification, ePosition, comprising the structured form of two sorts of text strings with a separation symbol like # is applied to identify a specific content and registered with the content at the same server. It is easy-to-realize and effective to solve the interoperability problem systematically and logically. Some APIs for the proposed CaaS service are to be converged to provide some upgraded cloud service model such as 'CaaS supported SaaS' and 'CaaS supported PaaS'.

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