• 한국패션뷰티학회지
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• 제5권4호
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• pp.145-148
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• 2007

The aims of this study was assess to preparation and stability of emulsion containing Taraxacum platycarpum ethanol extract our team was found to shape and size of capsule by optical microscope and Scanning Electron Microscope (SEM). In the stability test of the emulsion including Taraxacum platycarpum ethanol extract, it was stable of pH, viscosity during 30days. According to all the test results that have been given, it is possible that the ethanol extract of Taraxacum platycarpum can be used as a new cosmetics material.

• 생약학회지
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• 제50권2호
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• pp.118-123
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• 2019

Glutamate acts as an important neurotransmitter in brain. However, high concentration of glutamate showed an excitatory neurotoxicity and resulted to neuronal cell death. Neuronal cell death is known for one of the reason of Alzheimer's disease, a neurodegenerative disease. We tried to find neuroprotective medicinal plants by neuroprotection activity against glutamate injured HT22 cells as a model system. In the course of bioscreening of various medicinal plants, Taraxacum platycarpum extract showed significant neuroprotective activity. We tried to elucidate mechanisms of neuroprotective activity. T. platycarpum extract reduced ROS and intracellular $Ca^{2+}$ concentration increased by glutamate induced neurotoxicity. In addition, mitochondrial membrane potential was restored to the control level. Also, glutathione level, glutathione reductase and glutathione peroxidase activity were increased by T. platycarpum extract treatment. These data suggested that T. platycarpum showed neuroprotective activity via antioxidative activity.

• 대한본초학회지
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• 제21권4호
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• pp.109-113
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• 2006

Objectives : In this study, anti-oxidant activity of Taraxacum platycarpum is confirmed to investigate cosmeceutical activity for utilization as a cosmetic ingredients. Methods : In the anti-oxidant and whitening effect experiment, the electron donating ability of Taraxacum platycarpum extracts, their SOD-like activity, and the inhibitory activity of xanthine oxidase, tyrosinase were examined. Results : Radical-scavenging activity of water and ethanol extract was examined using ${\alpha},{\alpha}-diphenyl-{\beta}-picrylhydrazyl$ (DPPH). Water and ethanol extract from Taraxacum platycarpum showed 62.9% and 54.7% at 500 ppm concentration in DPPH radical inhibition, respectively. In the test of superoxide dismutase (SOD)-like activity, water extract showed 63.4% at 1,000 ppm concentration, while ethanol extract showed 49% at 1,000 ppm concentration. In the test of xanthine oxidase inhibition, ethanol extract showed 66.8% at 1,000 ppm concentration. Tyrosinase inhibition effect related to whitening effect showed 36.3% and 54.2% in ethanol extract and water extract at 1,000 ppm concentration, respectively. Conclusion : According to these results, it is possible that the extract of Taraxacum platycarpum can be used as a new natural material of cosmetic industry.

• 생약학회지
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• 제48권2호
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• pp.119-124
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• 2017

Taraxacum platycarpum H. Dahl. (Compositae) has been used as an anti-inflammatory or anti-cancer agent in the clinic. Although its antidepressant effect has been reported, however, its cognitive function is not investigated until yet. In the present study, we investigated whether the water extract of T. platycarpum (WETP) could improve cognitive function in cholinergic blockade-induced amnesia mouse model using the passive avoidance or Y-maze task. WETP (12.5, 25 or 50 mg/kg) significantly ameliorated the scopolamine-induced cognitive impairment both in the passive avoidance test and the Y-maze test. In addition, WETP significantly inhibited acetylcholinesterase (AChE) activity measured by an ex vivo study using the mouse whole brain. These results suggest that WETP alleviates the cognitive dysfunction caused by the cholinergic blockade, in part, via AChE inhibition, and that it may be a useful for treating cognitive dysfunction.

• 한국식품저장유통학회지
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• 제18권4호
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• pp.584-589
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• 2011

천연 갈변저해제 소재를 발굴하기 위하여 민들레와 감국을 열수 및 80% 에탄올로 추출하고, 그 추출물에 대하여 PPO 저해활성과 DPPH radical 소거능, 총페놀 함량 등을 통하여 항산화 효과를 조사하였다. 또한 추출물을 사과슬라이스에 침지하여 외관의 변화를 관찰하였다. 감국 추출물이 민들레 추출물보다 높은 PPO 저해활성을 보였으며 DPPH radical 소거능 그리고 총페놀 함량 등에 대해서 높은 함량을 나타내었다. 각 추출물에 대하여 사과 슬라이스에 침지하여 처리한 결과 감국 추출물에서 높은 L값과 낮은 ${\Delta}E$값을 보여 색 변화가 적게 일어났음을 알 수 있었다. 또한 감국의 경우 열수 추출물보다 에탄올 추출물에서 항산화 효과 및 PPO 저해활성력이 높은 것으로 조사되어 본 연구를 통하여 천연 갈변저해제로 감국 에탄올 추출물이 사용이 효과적일 것으로 사료된다.

• 한국식품조리과학회지
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• 제14권1호
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• pp.114-118
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• 1998

In ordo. to develop the natural food preservative agent, freeze dried dandelion (Taraxcum platycarpum) was extracted with several solvents, and antimicrobial activity was investigated. The methanol extract obtained from the dandelion exhibited antimicrobial properties against five strains such as Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Vibrio parahaemolyticus. The methanol extract at the concentration of 2000 $\mu\textrm{g}$/ml completely inhibited the growth of B. subtilis, E. coli, L. monocytogenes and V. parahaemolyticus. Antimicrobial activity of the ethylacetate fraction from the methanol extract of dandelion was the strongest fraction compare to those the other solvent fractions such as n-hexane, chloroform, n-butanol and water. The ethylacetate fraction showed the inhibitory effect at the concentration of 0.5 mg/disc on the growth of the food spoilage microorganisms.

• 한국미생물·생명공학회지
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• 제28권6호
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• pp.367-371
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• 2000

In order to develop a Korean traditional liquor using dandelion, alcohol fermentation condition was investigated. Etha-nol was produced maximally when 10% dandelion and 5% nuruk were added in cooked rice and fermented by S. cerevisiae at $25^{\circ}C$ for 10 days. The taste and nutraceutical properties of dandelion liquor with different concentra-tions(1%, 5%, 10%) of dandelion petal were compared. The dandelion-petal liquors which was brewed by addition of 1% dandelion petals into mash showed the best acceptability and its angiotensin-converting enzyme inhibitory activity was also high.

• 농약과학회지
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• 제3권1호
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• pp.46-50
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• 1999

민들레를 비롯하여 약용식물 9종 메탄올 추출물의 빨간 집모기, 집파리 유충 및 성충에 대한 살충력 실험을 실시하였다. 그 결과 빨간집모기(Culex pipiens pallens) 유충에 대하여는 솔(Pinus densiflora)잎, 고삼(Sophora angestifolia) 뿌리 등이 효과가 좋았다. 파리유충에 대한 살충효과는 민들레(Taraxacum platycarpum)잎 및 부추전초의 메탄올 추출물이 아주 높았으며, 백부근(Stemonae sessilifolia) 뿌리도 효과가 있는 것으로 밝혀졌으나 집파리(Musca domestica) 성충에 대한 살충효과는 크지 않았다.

• 한국분말재료학회지
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• 제26권3호
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• pp.225-230
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• 2019

To develop Taraxacum platycarpum extract (TP)-loaded particles for tablet dosage form, various TP-loaded particles composed of TP, dextrin, microcrystalline cellulose (MCC), silicon dioxide, ethanol, and water are prepared using a spray-drying method and fluid-bed-drying method. Their physical properties are evaluated using angle of repose, Hausner ratio, Carr's index, hardness, disintegrant time, and scanning electron microscopy. Optimal TP-loaded particles improve flowability and compressibility. Furthermore, 2% silicon dioxide gives increased flowability and compressibility. The formula of TP-loaded fluid-bed-drying particles at a TP/MCC/silicon-dioxide amount of 5/5/0.2 improves the angle of repose, Hausner ratio, Carr's index, hardness, and disintegrant time as compared with the TP-loaded spray-drying particles. The TP-loaded fluid-bed-drying particles considerably improve flowability and compressibility ($35.10^{\circ}$ vs. $40.3^{\circ}$, 0.97 vs. 1.17, and 18.97% vs. 28.97% for the angle of repose, Hausner ratio, and Carr's index, respectively), hardness (11.34 vs. 4.7 KP), and disintegrant time (7.4 vs. 10.4 min) as compared with the TP-loaded spray-drying particles. Thus, the results suggest that these fluid-bed-drying particles with MCC and silicon dioxide can be used as powerful particles to improve the flowability and compressibility of the TP.

• 식물분류학회지
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• 제34권2호
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• pp.153-166
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• 2004

동아시아에서 이배체의 유성생식과 무수정결실로 번식하는 민들레속의 종 분화 연구를 위해 한국산(2종4집단), 일본산(2종 4분류군 6집단), 대만산(1종 3집단)의 이배체 민들레 종의 두화형질을 측정하여 유집분석을 실시하였다. 두화형질은 두화의 크기, 외총포편의 형태와 길이, 외총포편 선단돌기 등의 식별형질을 포함하여 15개의 형질을 측정하였다. 이들 형질은 하나의 개체군내에서도 변이의 폭이 크고, 집단사이, 종들 사이에 있어서도 변이가 중첩되어 나타났다. 형태형질을 이용한 유집분석 결과 4개의 군(한국산과 T. japonicum군, T. platycarpum아종군, T. formosanum군, T. platycarpum subsp. hodoense군)으로 유집되었다. 한국산 좀민들레(이배체)와 산민들레(이배체, 삼배체)가 일본의 간사이 지방에 분포하는 T. japonicum과 같은 군으로 유집되었다는 것으로 보아 이들은 서로 가까운 유연관계를 가짐을 추측할 수 있다.