• Title/Summary/Keyword: TEM Journal

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Radiation Damage Mechanism of the Small Intestine's Absorptive Epithelium and Radioprotection Effect after Propolis Abdominal Cavity Injection (프로폴리스 복강 주사 후 소장 흡수상피조직의 방사선 손상 기전과 방어효과)

  • Ji, Tae-Jeong;Lee, Sang-Hun
    • The Journal of the Korea Contents Association
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    • v.10 no.7
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    • pp.297-304
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    • 2010
  • As Small Intestine Absorptive Epithelium Cells are surrounded by mucus polysaccharide and lymphocytes and mitochondria, they are sensitive to radiation energy. Damaged cells lead to a deficiency of nutrients and the imbalance of electrolyte metabolism, which in turn can becomes a major cause of an intestine tract death. This research observed ultra structures after injecting propolis into the abdominal cavity in order to reveal the radiation damage mechanism and radioprotection effect of intestine absorptive epithelium cells. The result of this research's observation found that stenosis occurred in the small intestine in some tissues 20 days after 5Gy irradiation, their surface turned black, and their elasticity dropped. Through observation with an optical microscope, it was found that the size of the goblet cells decreased, while the paneth granulate cells atrophied and were vacuolated. Observation with an transmission electron microscope(TEM) revealed that while microvill and lysosome were normally observed in jejunum tissues, mitochondria membrane was damaged and uneven surfaces were formed on lymphocytes. The membrane of absorptive epithelium cells hypertrophied in tissues of the ileum, and vacuole was observed. However, the observation after injecting propolis into the abdominal cavity found that mitochondria damage dropped dramatically, and radioprotection effects were to some extent confirmed, considering that glycocalyx of villi was clear, and M cells could be observed.

Characteristics of Workers' Exposure to Aerosolized Particles during the Production of Carbon Nanotube-enabled Composites (탄소나노튜브 복합체 취급 작업자의 공기 중 입자상 물질 노출 특성)

  • Kwon, Jiwoon;Kim, Sungho;Jang, Miyeon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.1
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    • pp.1-9
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    • 2020
  • Objectives: The purpose of this case study is to assess workers' exposure to carbon nanotubes(CNTs) and characterize particles aerosolized during the process of producing CNT-enabled polytetrafuoroethylene(PTFE) composites at a worksite in Korea. Methods: Personal breathing zone and area samples were collected for determining respirable concentrations of elemental carbon(EC) using NIOSH(National Institute for Occupational Safety and Health) Method 5040. Personal exposure to nano-sized particles was measured as the number concentration and mean diameter using personal ultrafine particle monitors. The number concentration by particle size was measured using optical particle sizers(OPS) and scanning mobility particle sizers(SMPS). Transmission electron microscopy (TEM) area samples were collected on TEM grids and analyzed to characterize the size, morphology, and chemistry of the particles. Results: Respirable EC concentrations ranged from 0.04 to 0.24 ㎍/㎥, which were below 23% of the exposure limit recommended by NIOSH and lower than background concentrations. Number concentrations by particle size measured using OPS and SMPS were not noticeably elevated during CNT-PTFE composite work. Instant increase of number concentrations of nano-sized particles was observed during manual sanding of CNT-PTFE composites. Both number concentrations and mean diameters did not show a statistically significant difference between workers handing CNT-added and not-added materials. TEM analyses revealed the emission of free-standing CNTs and CNT-PTFE aggregate particles from the powder supply task and composite particles embedded with CNTs from the computer numerical control(CNC) machining task with more than tens of micrometers in diameter. No free-standing CNT particles were observed from the CNC machining task. Conclusions: Significant worker exposure to respirable CNTs was not found, but the aerosolization of CNTs and CNT-embedded composite particles were observed during handing of CNT-PTFE powders and CNC machining of CNT-PTFE composites. Considering the limited knowledge on the toxicity of CNTs and CNT composite particles to date, it seems prudent to take a precautionary approach for the protection of workers' health.

The optical properties of GZO and ZnO thin films deposited by RF magnetron sputtering (RF magnetron sputtering 법으로 증착된 GZO와 ZnO 박막의 광학적 특성)

  • HwangBoe, S.J.;Jeon, H.H.;Kim, G.C.;Lee, J.S.;Kim, D.H.;Choi, W.B.;Jeon, M.H.
    • Journal of the Korean Vacuum Society
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    • v.16 no.6
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    • pp.453-457
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    • 2007
  • Zinc oxide (ZnO) and Ga doped zinc oxide (GZO) with different thickness in range of 10nm to 100nm are prepared on glass substrate by RF magnetron sputtering at room temperature. The structural and optical properties of the thin films is evaluated. The structural properties of ZnO and GZO are investigated by Tunneling Electron Microscopy (TEM) and scanning electron microscopy (SEM). Optical properties are also investigated by UV-VIS-NIR spectrophotometer (200$\sim$1400nm). The much larger grain size of ZnO compared to GZO decreased the light scattering at the grain boundary and improved the transmittance. The transmittance of ZnO is higher than that of GZO through all of the ranges of wavelengths. In case of over 50nm, we found that the transmittance of ZnO is 20% higher than that of GZO.

Microstructure and Morphology of Carbide Precipitates in $Ni_3Al$ and TiAl ($Ni_3Al$과 TiAl 중에 석출한 탄화물의 미세구조와 형태)

  • Han, Chang-Suk;Koo, Kyung-Wan;Kim, Jang-Woo
    • Journal of the Korean Society for Heat Treatment
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    • v.19 no.1
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    • pp.10-19
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    • 2006
  • Microstructure and morphology of precipitates in $Ni_3Al$- and TiAl-based intermetallics containing carbon have been investigated in terms of transmission electron microscopy(TEM). In an $L1_2$-ordered $Ni_3Al$ alloy with 4 mol.% of chromium and 0.2~3.0 mol.% of carbon, fine octahedral precipitates of $M_{23}C_6$ type carbide were formed in the matrix by aging at temperatures around 973 K after solution annealing at 1423 K. TEM examination revealed that the $M_{23}C_6$ phase and the matrix lattices have a cube-cube orientation relationship and keep partial atomic matching at the {111} interface. After prolonged aging or by aging at higher temperatures, the $M_{23}C_6$ precipitates then adopt a rod-like morphology elongated parallel to the <100> directions. In the $L1_0$-ordered TiAl containing 0.1~2.0 mol.% carbon, TEM observations revealed that needle-like precipitates, which lie only in one direction parallel to the [001] axis of the $L1_0$ matrix, appear in the matrix and preferentially at dislocations. Selected area electron diffraction(SAED) patterns analyses have shown that the needle-shaped precipitate is $Ti_3AlC$ of perovskite type. The orientation relationship between the $Ti_3AlC$ and the $L1_0$ matrix is found to be $(001)_{Ti3AlC}//(001)_{L10\;matrix}$ and $[010]_{Ti3AlC}//[010]_{L10\;matrix}$. By aging at higher temperatures or for longer period at 1073 K, plate-like precipitates of $Ti_2AlC$ with a hexagonal structure are formed on the {111} planes of the $L1_0$ matrix. The orientation relationship between the $Ti_2AlC$ and the $L1_0$ matrix is $(0001)_{Ti2AlC}//(111)_{L10\;matrix}$ and $_{Ti2AlC}//_{L10\;matrix}$.

Microstructure Characterization on Nano-thick Nickel Cobalt Composite Silicide on Polycrystalline Substrates (다결정 실리콘 기판 위에 형성된 나노급 니켈 코발트 복합실리사이드의 미세구조 분석)

  • Song, Oh-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.2
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    • pp.195-200
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    • 2007
  • We fabricated thermally-evaporated 10 nm-Ni/70 w-Poly-Si/200 $nm-SiO_2/Si$ and $10nm-Ni_{0.5}Co_{0.5}/70$ nm-Poly-Si/200 $nm-SiO_2/Si$ structures to investigate the microstructure of nickel monosilicide at the elevated temperatures required fur annealing. Silicides underwent rapid anneal at the temperatures of $600{\sim}1100^{\circ}C$ for 40 seconds. Silicides suitable for the salicide process formed on top of the polycrystalline silicon substrate mimicking the gates. A four-point tester was used to investigate the sheet resistances. A transmission electron microscope and an Auger depth profile scope were employed for the determination of cross sectional microstructure and thickness. 20nm thick nickel cobalt composite silicides on polycrystalline silicon showed low resistance up to $900^{\circ}C$, while the conventional nickle silicide showed low resistance below $900^{\circ}C$. Through TEM analysis, we confirmed that the 70nm-thick nickel cobalt composite silicide showed a unique silicon-silicide mixing at the high silicidation temperature of $1000^{\circ}C$. We identified $Ni_3Si_2,\;CoSi_2$ phase at $700^{\circ}C$ using an X-ray diffractometer. Auger depth profile analysis also supports the presence of this mixed microstructure. Our result implies that our newly proposed NiCo composite silicide from NiCo alloy films process may widen the thermal process window for the salicide process and be suitable for nano-thick silicides.

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Quality evaluations of bell pepper in cold system combined with TEM (thermoelectric materials) and PCM (phase change material) (PCM을 장착한 열전소자 냉각시스템의 저장 중 피망의 품질 평가)

  • Sung, Jung-Min;Kim, So-Hee;Kim, Byeong-Sam;Kim, Jong-Hoon;Kim, Ji-Young;Kwon, Ki-Hyun
    • Food Science and Preservation
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    • v.23 no.4
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    • pp.471-478
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    • 2016
  • For the distribution of fresh produce, the thermoelectric cooling system combined with thermo electric materials (TEM) and phase change material (PCM) was studied. The PCM used this study was produced by in-situ polymerization technology which referred microencapsulation of hydrocarbon (n-tetradecane and n-hexadecane). In this study, quality characteristics of bell peppers in thermoelectric cooling system combined with TEM and PCM were analyzed and control was placed in an EPS (expanded polystyrene) box. As a result of quality characteristics analysis, weight of bell peppers decreased and moisture content of bell peppers was 90.96~94.43% during storage. Vitamin C content of bell pepper decreased during storage and reduction ratio of control was higher than that of BPT-5 treatment(bell pepper in thermoelectric cooling system with PCM which is kept the temperature at $5^{\circ}C$). The result of color value, on 21 day, ${\Delta}E$ value of BPT-5 treatment was 5.05 while that of control was 41.8. On 21 day, total bacteria count of BPT-5 treated bell pepper shown less than that of control. In conclusion, it suggested that the thermoelectric cooling system combined with PCM improved quality of fresh produce during transportation and storage.

Preparation and characterization of CoAl2O4 blue ceramic nano pigments by attrition milling (어트리션밀을 이용한 CoAl2O4 나노 무기 안료의 제조 및 특성 평가)

  • Lee, Ki-Chan;Yoon, Jong-Won;Kim, Jin-Ho;Hwang, Kwang-Taek;Han, Kyu-Sung
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.23 no.5
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    • pp.255-264
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    • 2013
  • Cobalt aluminate ($CoAl_2O_4$) is a highly stable pigment with excellent resistance to light, weather, etc., which has resulted in widespread use as a ceramic pigment. Due to the unique optical characteristics, $CoAl_2O_4$ is generally used as a coloring agent to decorate porcelain products, glass, paints and plastics. Here, $CoAl_2O_4$ pigments were synthesized by polymerized complex method and solid state reaction. Then $CoAl_2O_4$ pigment were grinded using the attrition milling with 1 mm size zirconia ball for 3 hours. The attrition milling process was performed at the constant speed of 800 rpm and ball to powder weight ratio (BPR) was 100 : 1. The characteristics of synthesized pigment were analyzed by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), particle size analyser (PSA) and CIE $L^*a^*b^*$. The XRD patterns of $CoAl_2O_4$ show single phase spinel structure. The particle size of $CoAl_2O_4$ measured by FE-SEM, TEM and PSA analysis was in the range of 100~200 nm. The blue color of obtained $CoAl_2O_4$ pigments could be confirmed through CIE $L^*a^*b^*$ measurement.

Analysis on the Use Behavioral Patterns and Use Fluctuation over the Tong-Ch′on Amusement Park (동촌유원지의 이용실태 및 변동분석)

  • 김용수;임원현
    • Journal of the Korean Institute of Landscape Architecture
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    • v.15 no.1
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    • pp.17-37
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    • 1987
  • The purpose of this study is to establish more rational and practical planning theory for amusement park. It analyze and consider the fluctuation of people who come and use the Tong-Ch'on amusement park. The results drawn from this reserch work are as follows; 1. The main visitors of the Tong-Ch'on amusement park are students in their twenties and thirties, and people whose incomes are below 300,000 Won a month. The purpose of visit is for a rest rather than for amusement and user prefer summer, while the user is so rare in wintertime. Those phenomena observed are somewhat different from the real purpose of a amusement park which is on purpose to make profits by offering entertainments to the users. So planner should pay attention to the three points. They are varieties, seasonable diversification and fantastic character of facilties, in the amusement park. 2. The access time of the Tong-Ch'on amusement park was 41 minutes, the use frequency was 4 times a year and resident time was 164 minutes. The relationship of the three factors are as follows; log Y(F) =1.7832-0.0277(A.T) R$^2$=0.75 Y(R. F)=31.8885+3.3217(A.T) R$^2$=0.53 Y(R. T)=224.8959-87.8309 1og(F) R$^2$=0.38 F;Use frequency(time/year) A.T;Access Time(minute) R.T;Resident Time(minute) 3. In the choice of space, there were much differences according to tole user's age, job, degree of education, companion type and purpose of use. 4. There are considerable correlation between use fluctuation and some factors. The factors are season(summer, winter) as a time, temperature, cloud amount, duration of sunshine, weather(rainy-day) as a climate and a day of the week(weekday, holiday) as a social system. The important variables are temperature, cloud amount, duration of sunshine and a day of the week(weekday, holiday) to estimate the user of amusementpark. 5. 1 can reduce the following two types of regression models. 1) log$\sub$e/ Y1 = 6.9114 + 0.l135 TEM + 0.00002 SUN -0.4068W1 + 0.4316 W3 (R$^2$= 0.94) 2) log$\sub$e/ Y2 = 7.2069 + 0.l177 TEM - 0.0990 CLO + 0.4880 W3 (R$^2$=0.95) Y; Number of User TEM; Temperature CLO; Amount of cloud SUN; Duration of Sunshine W1; Weekday W3; Holiday Those model is in order to estimate the user for management of Tong-Ch'on amusement park and use on the computation of facility sloe for reconstruction. Besides the amusement park, city park and outdoor recreation area could estimate of user through this method. But, I am not sure about the regression models because I did not apply the regression models to the other amusement park, city Park or outdoor recreation area. Therefore, I think that this problem needs to be studied on in the future.

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A Study on the Self-annealing Characteristics of Electroplated Copper Thin Film for DRAM Integrated Process (DRAM 집적공정 응용을 위한 전기도금법 증착 구리 박막의 자기 열처리 특성 연구)

  • Choi, Deuk-Sung;Jeong, Seung-Hyun
    • Journal of the Microelectronics and Packaging Society
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    • v.25 no.3
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    • pp.61-66
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    • 2018
  • This research scrutinizes the self-annealing characteristics of copper used to metal interconnection for application of DRAM fabrication process. As the time goes after the copper deposited, the grain of copper is growing. It is called self-annealing. We use the electroplating method for copper deposition and estimate two kinds of electroplating chemicals having different organic additives. As the time of self-annealing is elapsed, sheet resistance decreases with logarithmic dependence of time and is finally saturated. The improvement of sheet resistance is approximately 20%. The saturation time of experimental sample is shorter than that of reference sample. We can find that self-annealing is highly efficient in grain growth of copper through the measurement of TEM analysis. The structure of copper grain is similar to the bamboo type useful for current flow. The results of thermal excursion characteristics show that the reliability of self-annealed sample is better than that of sample annealed at higher temperature. The self-annealed sample is not contained in hillock. The self-annealed samples grow until $2{\mu}m$ and develop in [100] direction more favorable for reliability.

A Study on Radio-Protection Mechanism of Platelet Cells After Injection of Alliin (알리인 투여 후 혈소판의 방사선 방어기전 연구)

  • Ji, Tae-Jeong
    • Journal of radiological science and technology
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    • v.33 no.3
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    • pp.185-192
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    • 2010
  • Platelets originating from Megakaryocyte are sensitive to radiation along with white blood cells, and thus these platelets are used as an index of radiation hazard as they decrease in advance. Thus, when there is a scarcity of platelets, dot hemorrhage occurs and it leads to decrease of blood corpuscle and a decline in immunity. In particular, when 4~6 Gy whole body irradiation is received, after three weeks, the platelets will decrease to the lowest level, which can be a cause of death by bleeding and anemia. Therefore, this study tried to identify the mechanism of platelet damage and protection effect. The protection substance used in the experiment is Alliin, which is a component of garlic, and it was observed by an Transmission Electron Microscope(TEM) after its injection to the rat's tail vein. In the study, it was found that the cell membrane was severely damaged in a 10-day progressed platelet organ after receiving 5 Gy irradiation. It billowed as balloon-like figure and the glycocalyx became hyperplasia. The minute organ was damaged to the point that it was beyond recognition in a 20-day progressed platelet organ after receiving irradiation, and the cytoplasmic contents were exposed to epilepsy parts and outrageously damaged. Furthermore, the form of granules could also not be observed. A hole was formed in the middle, and the damaged organ was found in a 30-day progressed platelet. However, the form of granules was consistently maintained in the experiment group injecting Alliin, as with the control group, and there was no damage to the cell membrane recognized. Thus, it was possible to verify the effectiveness of radiation protection of the platelet when Alliin was injected to the blood vessel.