• Journal of Korean Neurosurgical Society
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• v.61 no.3
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• pp.376-385
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• 2018

Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became the significant step in the diagnosis, the prediction of prognosis and the treatment of brain tumor. Because traditional molecular testing methods have limitations in time and cost for multiple gene tests, next-generation sequencing technologies are rapidly introduced into clinical practice. Targeted sequencing panels using these technologies have been developed for brain tumors. In this article, focused on pediatric brain tumor, key discoveries of brain tumor-related genes are reviewed and cancer panels used in the molecular profiling of brain tumor are discussed.

• 한국정보통신설비학회:학술대회논문집
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• 2007.08a
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• pp.173-175
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• 2007

So far, almost all IP media services are targeted to the specific devices, for example, IPTV services are mainly for TV, and social community services are mainly for PC etc.. This paper describes newly developed media service platform in which the high quality video services can be provided not only to the TV or PC but also to the PMP(Portable Media Player) and even to the mobile phone. The major technical issues of the service platform are synchronization of contents among the different devices and high quality TV grade video display in PMP device. We confirmed successful operation of multi-device converged services in the developed media platform. We also have a trial service plan in Gwangju city at the end of this year.

• Review of KIISC
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• v.26 no.6
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• pp.42-50
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• 2016

Critical infrastructure (CI) such as the electrical grid, transportation systems and water resource systems are controlled by Industrial Control and SCADA (Supervisory Control and Data Acquisition) networks. During the last few years, cyber attackers have increasingly targeted such CI systems. This is of great concern because successful attacks have wide ranging impact and can cause widespread destruction and loss of life. As a result, there is a critical requirement to develop enhanced algorithms and tools to detect cyber threats for SCADA networks. Such tools have key differences with the tools utilized to detect cyber threats in regular IT networks. This paper discusses key factors which differentiate network security for SCADA networks versus regular IT networks. The paper also presents various approaches used for SCADA security and some of the advancements in the area.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.2
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• pp.208-213
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• 2003

Recently, a variety of new routing protocols targeted specifically wireless mobile nodes environment have been developed. This paper presents the results of a detailed packet level simulation comparing two multi-hop wireless ad-hoc network routing protocols that cover a range of design choices between DSDV and DSR. And we suggest a performance comparison of network routing protocols through NS-2 simulator.

• Korean Management Science Review
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• v.34 no.1
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• pp.57-70
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• 2017

The phenomenon of increasing aging population is one of the crucial social and economic issues in these day. In this paper, drawn from the industrial application cases and relevant literatures, we present the typology of ICT convergent applications targeted for silver generation, referred as silver ICT. Subsequently, the contributional value of ICT as the enabling technology is estimated. We firstly conduct keyword search to collect currently used silver ICT applications. Secondly, drawn from the social welfare literature, we organize distinctive needs of the silver generations. Then, on the basis of task technology fit framework, typology of ICT enabled silver applications is organized through the fit of ICT in the sense of fulfilling those silver needs. Finally, using the industry input-output table figures, potential ICT contributions for silver ICT are estimated. The proposed silver ICT typology and ICT contributions provides useful insights for further research in the area of ICT convergence and silver market research.

• Journal of The Korea Institute of Healthcare Architecture
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• v.8 no.2
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• pp.35-41
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• 2002

Being rapidly increased in population of the Elderly supporting of the Elderly is no longer family's and personal problems. It is social issue that demand measures by the government. Though many kinds of welfare policies for the Elderly have been established, it is not sufficient both in quality and quantity. In order to support residents of region, welfare facilities which based on community welfare have been supplied. This study is targeted on health facility for the elderly of Japan. First purpose, it is to acheive basic information about health facility. Second purpose of this study is to basic data for planning of facility.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.65 no.4
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• pp.321-325
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• 2016

The purpose of this study was to develop a system capable of operating a digital signage system at a low cost by utilizing existing equipment (TV, monitors, tablet PC, etc.). In particular, by developing an easy way to install the store's small business owners it can operate their small business installing digital signage in the store in addition to a public place. This easily exposed by a targeted advertising and local advertising and information of each store customers can maximize the advertising effect.

• Biomolecules & Therapeutics
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• v.25 no.1
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• pp.57-68
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• 2017

Seven transmembrane receptors (7TMRs), also known as G protein-coupled receptors, are popular targets of drug development, particularly 7TMR systems that are activated by peptide ligands. Although many pharmaceutical drugs have been discovered via conventional bulk analysis techniques the increasing availability of structural and evolutionary data are facilitating change to rational, targeted drug design. This article discusses the appeal of neuropeptide-7TMR systems as drug targets and provides an overview of concepts in the evolution of vertebrate genomes and gene families. Subsequently, methods that use evolutionary concepts and comparative analysis techniques to aid in gene discovery, gene function identification, and novel drug design are provided along with case study examples.

• Journal of Plant Biotechnology
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• v.8 no.1
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• pp.9-14
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• 2006

As an alternative method to produce low cost reagents for immunodiagnosis and protect the plants from viral disease, a gene encoding a single chain variable fragment(scFv) recombinant antibody targeted to the coat protein of cucumber mosaic virus (CMV) was expressed in Nacotiana tabacum. The source of the scFv recombinant antibody gene was from spleen tissue of an immunized mouse. The gene was initially cloned into the pCANTAB5E phagemid and expressed in E. coli. In the following study, the antibody gene was subcloned into the plant expression vector, pCAMBIA-1301 and introduced into tobacco leaf tissue via Agrobacterium tumefacients mediated transformation. After transformation, 56 out of 58 plants were shown to carry the desired anti-CMV scFv gene by PCR analysis. Overall, only 12.5% of the 56 putative transgenic plants were found to express the antibody to a detectable level.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11b
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• pp.228-233
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• 2002

General modeling of a resonant shunting damper has been made from piezoelectric sensor/actuator equation. It is found that an additional damping, which is augmented to a system, is generated by the shunt damping effect. The transfer function of the tuned electrical absorber is derived for both series and parallel shunt circuit. The governing equations and associated boundary conditions are derived using Hamilton's Principle. The shunt voltage equation is also derived from the charge generated in PZT due to beam vibration. The frequency response function of the obtained mathematical model is compared with that of the tuned electrical absorber and experimental work. The vibration amplitude is reduced about 15 dB at targeted second mode frequency.