• 한국응용과학기술학회지
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• 제40권4호
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• pp.699-709
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• 2023

This study is to establish optimizing condition of alcohol fermentation in vinegar production with aronia, to confirm whether this can be industrially used, and to compare and analyze a change in anti-oxidative activity and quality characteristic according to alcohol fermentation of aronia. The optimized conditions for alcohol fermentation were as follows: Saccharomyces cerevisiae 5645 of yeast strain, a 5% inoculum size, aronia juice with a brix value of 14, and a glucose content of 7%. As a result to conduct scale up with optimizing conditions of alcohol fermentation of aronia, 8 days (192 hrs) of total alcohol fermentation time and 7.4% of the final alcohol content. The harvest volume accounted for approximately 90.2% with a loss of about 2.8%. As a result of antioxidant test, anti-oxidative activity of alcohol fermented liquor is lower than anti-oxidative activity of aronia extract, because of the decrease of antioxidant by oxidation of the fermentation process. However, the decrease of tannin by the fermentation process reduces acerbity of aronia, so increases overall preference

• Journal of Microbiology and Biotechnology
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• 제13권4호
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• pp.483-486
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• 2003

3'-[S-Methyl-cysteinyl]-3'-amino-3'-deoxy-N,N- dimethyl adenosine, cystocin, is a biosynthesized antibiotic material newly identified from Streptomyces sp. GCA0001. Its structure was found to be similar to puromycin, where the terminal tyrosine is replaced by a methyl cysteine. NMR data prove that the 3-ammo ribose is connected to dimethylaminopurine through the anomeric carbon at 1'-carbon. The methyl cysteinyl unit is connected to the amino unit of ribose by peptide bond. The verification of the structure was performed by comparing the puromycin nucleosides resulted from the hydrolysis of cystocin and puromycin, respectively. Antibiotic activity of cystocin against Streptococcus was found to be two times more potent than that of puromycin.

• Journal of Astronomy and Space Sciences
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• 제16권1호
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• pp.53-60
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• 1999

태양에 의한 위성전파교란으로 인해 통신이 두절되는 태양간섭 현상(Sun Transit Outage)을 예측해 보았다. 지금까지의 연구는 주로 정지위성의 경우에 국한되었고, 태양모델도 흑점 극소기때의 태양을 가정한 경우가 대부분이었다. 본 연구에서는 정지위성의 경우뿐 아니라 최근에 그 수요가 급증하고 있는 비 정지위성의 경우에도 그 발생가능성을 예측해 보았다. 특히 11년 주기의 태양표면에서의 활동 변화를 고려하여 태양 간섭현상을 보다 정확히 예측해 보았으며 그 영향을 하향링크의 주파수에 따라 알아보았다. 또한 연구 결과를 실제 운용되고 있는 무궁화위성 시스템에 적용시켜보았다.

• 생약학회지
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• 제23권1호
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• pp.34-42
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• 1992

The analgesic, anticonvulsant and anti-inflammatory actives of leaves of Hedera rhombea Bean were evaluated. The methanol and butanol fractions showed considerable analgesic activity, but no anticonvulsant activities. Anti-inflammatory activity was found in the methanol, butanol and ether fractions by carrageenin induced edema test.

• 한국약용작물학회지
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• 제24권2호
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• pp.129-135
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• 2016

Background: In this study, we investigated the antibacterial and nitric oxide (NO) production inhibitory activities of 75% ethanol extract of Prunus sargentii branches and its fractions against acne pathogens. Methods and Results: The antibacterial activity against acne causing pathogens was determined using the disc diffusion assay. The ethyl acetate fraction showed higher activities against Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis than those shown by other fractions. In the DPPH radical and NO scavenging assays, the butanol fraction showed strong DPPH radical and NO scavenging abilities. These activities were related to the total polyphenol and flavonoid contents of butanol fraction. On the other hand, the chloroform and ethyl acetate fractions exhibited the highest NO production inhibitory activity in Lipopolysaccharide (LPS)-stimulated Raw 264.7 cells compared to those exhibited by other fractions. Conclusions: The extract and its ethyl acetate fraction from the branches of P. sargentii exhibited antibacterial activity and could be used as functional materials in antimicrobial related fields. Moreover, the chloroform and ethyl acetate fractions are potential antiinflammatory agents and butanol fraction acts as an effective radical scavenger.

• 대한미생물학회지
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• 제6권1호
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• pp.9-13
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• 1971

The bacterial substance inhibited the methylene blue-uptaking activity of red cells. On keeping at room temperature the methylene blue-uptaking activity of red cells sensitized with bacterial substance was more rapidly destroyed than that of normal cells. The methylene blue-uptaking activity of red cells was more inhibited by the supernatant fraction than sediment of bacterial substance.

• 한국어병학회지
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• 제19권3호
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• pp.285-288
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• 2006

The respiratory burst activity of tilapia (Oreochromis mosambicus) phagocytes agaisnt Edwardsiella tarda ghosts produced by gene E mediated lysis was investigated. Stimulation with E. tarda ghosts (ETG) showed markedly higher respiratory burst activity than that with formalin killed E. tarda (FKC) in phagocytes. This result may suggest that ETG can induce effective cellular immune responses in fish.

• Archives of Pharmacal Research
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• 제26권3호
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• pp.197-201
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• 2003

Novel $\beta$-hydroxy propenamides as analogues of the active metabolite of leflunomide (A 771726) were synthesized and evaluated for their inhibitory activity on dihydroorotate dehydrogenase (DHODH) in an investigation into their immunosuppressive activity. Compounds 2a, 3a, and 3h were approximately 4-40 times more potent than leflunomide in their activity while they were-less active than A 771726.

• 대한인간공학회지
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• 제2권1호
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• pp.13-21
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• 1983

Small group activity in Korea was introduced from the United States as QC circle, ZD group movements and the like, but it has developed into a Korean style from so-called factory saemaul panel activities contributing much to the management of enterprises. Based on human motivation theory, the principles to activate small group activity is suggested on which a new diagnosis of small group activity is proposed here. It is consisted of checklist and radarchart. The factor to activate small group activity have been obtained in terms of multivariate analysis for data from the new diagnosis.

• 한국수산과학회지
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• 제54권3호
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• pp.271-279
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• 2021

Ultrasound-assisted extraction (UAE) conditions, including extraction time, extraction temperature, and ethanol concentration, were optimized to increase the total flavonoid content (TFC), tyrosinase inhibitory activity (TIA), and collagenase inhibitory activity (CIA) of Spirulina platensis through central composite design (CCD). For the optimization of the three dependent variables, a quadratic regression model was derived from 17 experimental sets for the simultaneous maximization of TFC, TIA, and CIA. The predicted optimal UAE conditions were 44.0 min of extraction time, 82.8℃ of extraction temperature, and 96.0% of ethanol concentration. Under these conditions, 0.93 mg QE/g DM of TFC, 81.9% of CIA, and 92.1% of TIA were predicted. The CCD-based UAE optimization enabled an increase in TFC, CIA, and TIA, thereby confirming that the S. platensis extract can be used in the development of a cosmetic material with skin whitening and anti-wrinkle effects.