• 한국수산과학회지
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• 제6권3_4호
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• pp.97-100
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• 1973

In the previous work(Kim et al, 1973), the quality of sun-dried Alaska pollack, Theragra chalch-ogramma, was discussed in the aspect of non-enzymatic discoloration as a function of relative humidity during storage at room temperature($20^{\circ}C$). In this paper, sun-dried squid, Ommastrephes steam pacificus was investigated at the same aspect mentioned above. Fresh squid from the whole sale market was dressed, filleted, dried for 48 hours in the open air and finally stored in the humidistat chamber. Lipid oxidation ana development of non-enzymatic browning were tested by the same methods described in the previous paper. The TBA value showed a maximum peak on 30 day storage, hereafter tended to decrease gradually. The rate of browning, however, in water soluble fraction as well as in chloroform-methanol fraction was lower at 0.34 to 0.45 water activity than at any other case, and propagation of lipid oxidation was also diminished at the above level of water activity. From the results, it is recognized that storage at Aw=0.34 to 0.45 provides higher quality stability for sun-dried squid.

• Food Science and Biotechnology
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• 제15권3호
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• pp.466-468
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• 2006

The antimicrobial effect of a novel flavonoid (7-O-butyl naringenin) on Helicobacter pylori ATCC 26695 and its inhibitory effects on the urease activity of the strain were evaluated by comparing with quercetin and naringenin. H. pylori was cultured with brain heart infusion supplemented with 5% horse serum at $37^{\circ}C$ under 10% $CO_2$ atmosphere and the inhibitory effects of flavonoids against the strain were detected using micro-plate methods. During 12 hr of incubation time, the optical densities of phenol red reduced (pink color) in the urea broth by producing ammonia were detected at 560 nm with a spectrophotometer. The results indicated that both quercetin and 7-O-butyl naringenin were effective against the growth of H. pylori. Moreover, inhibitory effect of 7-O-butyl naringenin on the growth of H. pylori was about two-fold higher than quercetin at the same concentration. With regard to H. pylori urease activity, 7-O-butyl naringenin had a greater inhibitory effect than did naringenin or quercetin at the same concentration.

• International Journal of Industrial Entomology and Biomaterials
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• 제5권2호
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• pp.195-199
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• 2002

In order to find potential anticancer agents, we extracted pheophytin in the silkworm feces from various larval stages by water, chloroform and methanol extraction. The cytotoxicity of the pheophytin extracts of various silkworm feces was measured in the CT-26 cells originated from murine metastatic colon cancer, by dye uptake assay. The cytotoxicity of those pheophytins in 2nd, 3rd and 4th instars was better than remaining larval stages. The in vitro anticoagulant and fibyinolytic activities of ethanol extract from varietal mulberry leaves, mulberry branches and silkworm feces and pheophytin extracts from silkworm feces obtained at various larval stages were evaluated in order to find effective therapeutic drugs for the treatment of myocardial and cerebral thrombosis. The fibrinolytic activity was tested using the activated partial thromboplastin time (APTT) and thrombin time (TT) was measured for blood clotting activity. With regards to the fibrinolytic system, ethanol extracts of silkworm feces were better than varietal mulberry leaves and mulberry branches. The pheophytin extracts from 7th days of 5th instar contained the highest percentage of pheophytin and good fibrinolytic activity.

• 한국작물학회지
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• 제50권spc1호
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• pp.220-223
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• 2005

최근 뽕잎과 더불어 기능성 및 천연색소 자원으로서 뽕나무의 열매인 오디가 새로운 작목으로 유망시 되고 있다. 농가의 소득향상은 물론 소비자의 관심과 수요에 부응하기 위한 연구의 일환으로 오디를 수확하여 신경세포 보호활성과 항균활성에 대한 오디 추출물의 효능을 평가함으로써 오디의 기능성 및 이용성을 증대시키고자 하였다. 그 결과를 요약하면 다음과 같다. 1. 신경독성 물질 $H_2O_2$처리에 의해 유도되는 신경세포사에 대하여 오디 추출물 $10{\mu}g/ml$의 농도 처리시 $37\%$의 세포보호 효과를 나타냈으며, Oxygen-glucose deprivation (OGD)에 의하여 유발된 뇌허혈 모델에서는 오디 C3G의 경우 농도 의존형으로 세포괴사를 막았다. 특히 cyanidin의 경우는 $10{\mu}g/ml$의 농도에서 $70\%$이상의 뇌세포보호 효과를 나타냈다. 2. 오디 추출물과 C3G의 항균활성을 검정한 결과, 청일뽕 오디의 MeOH 추출물의 항균 활성이 가장 높았으나, Salmonella typhimurium 의 경우 모든 처리군에서 $70\%$ 이상의 억제 활성을 나타냈다. 모든 처리군에서 $50{\mu}l$농도보다 $100{\mu}l$농도에서 균주의 억제 활성이 높게 나타났다.

• 기본간호학회지
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• 제15권2호
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• pp.178-185
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• 2008

Purpose: This study was done to investigate the relationship between depression, self-care activity and $HbA_1c$ in clients with type-2 diabetes mellitus (DM) clients. Method: This was a cross sectional descriptive study and data were collected between October 4 and 27, 2006 using a questionnaire. The participants were inpatients and outpatients with type-2 diabetes being seen in one of two hospitals. The questionnaire included general as well as disease related characteristics, a depression scale (CES-D), and the self-care activity scale developed by Kim (1996). $HbA_1c$ was obtained from medical records. Results: There were 50 men (41.7%) and 70 women (58.3%). The mean scores for depression and self-care activity were $18.22{\pm}10.03$ and 3.51, respectively. Almost half of the Participants (46.7%) had an $HbA_1c$ greater than 7%. Self-care activity was negatively correlated with depression (r=-.436, p=0.00) and $HbA_1c$ (r=-.269, p=0.03). Depression was positively correlated with $HbA_1c$ (r=-.325, p=0.00). Participants who had diabetes education showed a significantly lower level of $HbA_1c$ than the group who had never had diabetes education. Conclusions: It is Important to make ensure that patients with diabetes have education on diabetes mellitus and to screen and manage depression as part of the care for these patients.

• 한국식품영양과학회지
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• 제44권8호
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• pp.1144-1149
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• 2015

식용 표고버섯을 acetone, ethyl acetate 및 ethanol 등 여러 용매로 추출하여 각 추출용매에 따른 표고버섯 추출물의 항산화 및 항균 활성을 측정하였다. 추출물은 최소 농도인 98 mg/mL에 맞추어 모든 실험을 진행하였다. 표고버섯의 폴리페놀 함량은 유의적 차이는 보이지 않았으나 극성이 큰 ethanol 추출물이 acetone 추출물과 ethyl acetate 추출물보다 다소 높게 조사되었으며, ABTS 라디칼 소거능에서도 유사한 경향을 확인하였다. 반면에 플라보노이드 함량과 DPPH 라디칼 소거능은 ethyl acetate와 acetone 추출물이 ethanol 추출물보다 다소 높게 조사되었다. 폴리페놀과 플라보노이드 함량은 낮았지만 DPPH 라디칼 소거능에서 항산화 활성을 확인할 수 있었으며, 특히 ABTS 라디칼 소거능은 86.8~98.5%로 표준물질 항산화제인 ascorbic acid보다 좀 더 높은 항산화 활성을 확인하였다. 표고버섯의 다재 내성 관련 항균 활성은 ethyl acetate 추출물이 6종의 다제 내성 균주인 3종의 그람 양성균 Bacillus subtilis, Staphylococcus aureus 및 Micrococcus luteus와 3종의 그람 음성균 Escherichia coli, Pseudomonas aeruginosa 및 Enterobacter cloacae 등 모두에서 항균 활성을 가지고 있는 것을 확인하였다. 특히 B. subtilis에 대하여 가장 높은 항균활성을 보였으며, P. aeruginosa, M. luteus, Ent. cloacae 및 B. subtilis에서는 acetone, ethyl acetate 및 ethanol 추출물 모두에서 항균 활성을 확인할 수 있었다.

• 한국동물학회:학술대회논문집
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• 한국동물학회 2005년도 제60회 한국생물과학협회 정기학술발표대회
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• pp.18-18
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• 2005

• Applied Biological Chemistry
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• 제51권4호
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• pp.338-341
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• 2008

• 복식문화학회:학술대회논문집
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• 복식문화학회 1998년도 International Costume Culture Conference
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• pp.18-19
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• 1998

• 천문학회보
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• 제28권2호
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• pp.86-86
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• 2003