• Animal cells and systems
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• v.15 no.4
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• pp.268-273
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• 2011

Transgenic mice expressing green fluorescent protein (GFP) under the control of human glial fibrillary acidic protein promoter (hGFAP) have been utilized for in vivo labeling of astrocytes. Although it has been considered that virtually all astrocytes express GFP in this transgenic mouse, we found that different subsets of GFAP-expressing astrocytes express considerably different levels of GFP in the adult brain. Astrocytes in the spinal cord, the molecular layer of thecerebellum, meninges, white matter, corpus callosum and blood vessels exhibited strong GFP, whereas subsets of astrocytes associated with granule cells in the cerebellum and dentate gyrus did not or only marginally exhibited GFP. We also found that a small subset of GFP-expressing cells in the periglomeruli of the olfactory bulb did not express GFAP immunoreactivity. Collectively, these results suggest that human GFAP promoter-derived GFP expression does not faithfully recapitulate the endogenous GFAP expression in mice, suggesting that upstream regulatory mechanisms controlling GFAP transcription are different in different populations of astrocytes, and may reflect the functional diversity of astrocytes.

• Journal of the Korean Society for information Management
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• v.17 no.1
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• pp.129-148
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• 2000

Experiments were performed on three subsets of a Korean test collection in order to determine whether 2-Poisson model's Z value is a good measure for selecting subject words from a document to be indexed. It was found that subject word selection based on the Z value was effective for only one subset with short texts, i.e., the Science and Technology subset. Correlation analyses between 2-Poisson model's Z and TF.IDF weight for the three subsets showed that the correlation was relatively high for two test subsets with short texts, i.e., the Science and Technology subset and the Newspaper subset.

• Clinical and Experimental Reproductive Medicine
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• v.16 no.2
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• pp.147-152
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• 1989

The purpose of this study is to detect certain change in peripheral blood lymphocyte subpopulations in women with premature ovarian failure. The B cells, T cells and subsets were counted in 21 women with premature ovarian failure and 30 age-matched normal control women. The B cells were measured by identifying lymphocyte with surface membrane immunoglobulin and T cells and subsets by indirect immunofluorescence technique with the monoclonal antibodies OK T3, OK T4, and OK T8. The results were as follows. 1. No significant difference in the absolute number of B cells, T cells and subsets between women with premature ovarian failure and normal control women was observed. 2. The percentage of B cells, T cells and OK T8(+) cells in women with premature ovarian failure was not significantly different from that in normal control subjects respectively. 3. The percentage of OK T4(+) cells and OK T4/0K T8(+) ratio was significantly higher in women with premature ovarian failure than in control subjects.

• IMMUNE NETWORK
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• v.12 no.2
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• pp.48-57
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• 2012

Acute viral encephalitis caused by neurotrophic viruses, such as mosquito-borne flaviviruses, is an emerging and re-emerging disease that represents an immense global health problem. Considerable progression has been made in understanding the pathogenesis of acute viral encephalitis, but the immune-pathological processes occurring during the progression of encephalitis and the roles played by various molecules and cellular components of the innate and adaptive systems still remain undefined. Recent findings reveal the significant contribution of Toll-like receptors (TLRs) and regulatory $CD4^+$ T cells in the outcomes of infectious diseases caused by neurotrophic viruses. In this review, we discuss the ample evidence focused on the roles of TLRs and $CD4^+$ helper T cell subsets on the progression of acute viral encephalitis. Finally, we draw attention to the importance of these molecules and cellular components in defining the pathogenesis of acute viral encephalitis, thereby providing new therapeutic avenues for this disease.

• Communications of the Korean Mathematical Society
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• v.33 no.4
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• pp.1341-1356
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• 2018

The author devotes this paper to defining a new class of generalized soft open sets, namely soft somewhere dense sets and to investigating its main features. With the help of examples, we illustrate the relationships between soft somewhere dense sets and some celebrated generalizations of soft open sets, and point out that the soft somewhere dense subsets of a soft hyperconnected space coincide with the non-null soft ${\beta}$-open sets. Also, we give an equivalent condition for the soft csdense sets and verify that every soft set is soft somewhere dense or soft cs-dense. We show that a collection of all soft somewhere dense subsets of a strongly soft hyperconnected space forms a soft filter on the universe set, and this collection with a non-null soft set form a soft topology on the universe set as well. Moreover, we derive some important results such as the property of being a soft somewhere dense set is a soft topological property and the finite product of soft somewhere dense sets is soft somewhere dense. In the end, we point out that the number of soft somewhere dense subsets of infinite soft topological space is infinite, and we present some results which associate soft somewhere dense sets with some soft topological concepts such as soft compact spaces and soft subspaces.

• BMB Reports
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• v.47 no.2
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• pp.60-68
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• 2014

Psoriasis is a chronic inflammatory disorder characterized by an erythematous scaly plaque of the skin and is occasionally accompanied by systemic complications. In the psoriatic lesions, an increased number of cytokine-producing dendritic cells and activated T cells are observed, which indicate that psoriasis is a prototype of an immune-mediated dermatosis. During the last decade, emerging studies demonstrate novel roles for the dendritic cell subsets in the process of disease initiation and maintenance of psoriasis. In addition, recently discovered anti-psoriatic therapies, which specifically target inflammatory cytokines produced by lesional dendritic cells, bring much better clinical improvement compared to conventional treatments. These new therapies implicate the crucial importance of dendritic cells in psoriasis pathogenesis. This review will summarize and discuss the dendritic cell subsets of the human skin and their pathophysiological involvement in psoriasis based on mouse- and patient-oriented studies.

• The Korean Journal of Nuclear Medicine
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• v.25 no.1
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• pp.110-116
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• 1991

To elucidate alteration of peripheral T cell subsets in thyroid tumors, the author enumerated T cell subsets in periphral blood by indirect immunofluorescent method, using monoclonal antibodies (CD3, CD4 and CD8) in 17 cases of thyroid cancer, 12 cases of thyroid adenoma, and 16 cases of adult healthy subjects as controls. Diagnoses were confirmed histopatologically in thyroid cancer and adenoma, and were established on the basis of commonly accepted clinical and biochemical criteria in Hashimoto's thyroiditis. The blood was drawn from veins of the patients and control subjects in Pusan National University Hospital during the period of January to October 1990. The results obtained were summarized as follow: 1) The percentage of CD3+ cells was significantly decreased in thyroid cancer as compared with healthy subjects. 2) The percentage of CD4+ cells was not different among thyroid cancer, thyroid adenoma, Hashimoto's thyroiditis and control subjects each other. 3) The percentage of CD8+ cells was significantly decreased in thyroid cancer as compared with adult healthy subjects, and tended to be decreased as compared with thyroid adenoma and Ha-shimoto's thyroiditis. 4) The CD/CD8 ratio was significantly increased in thyroid cancer as compared with control subjects, and tended to be increased as compared with thyroid adenoma and Hashimoto's thyroiditis. On the basis of the results, it can be suggested that the immunodysfunction may be due to decreased soppressor/cytotoxic T cells in thyroid cancer.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.9
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• pp.4418-4437
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• 2017

In this paper a three-phase secure compressive sensing (CS) and received signal strength (RSS) based target localization approach is proposed to mitigate the effect of malicious node attack. RSS measurements are first arranged into a group of subsets where the same measurement can be included in multiple subsets. Intermediate target position estimates are then produced using individual subsets of RSS measurements and the CS technique. From the intermediate position estimates, the residual error vector and residual error square vector are formed. The least median of residual error square is utilized to define a verifier parameter. The selected residual error vector is utilized along with a threshold to determine whether a node or measurement is under attack. The final target positions are estimated by using only the attack-free measurements and the CS technique. Further, theoretical analysis is performed for parameter selection and computational complexity evaluation. Extensive simulation studies are carried out to demonstrate the advantage of the proposed CS-based secure localization approach over the existing algorithms.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.11
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• pp.4087-4102
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• 2014

Two-way relaying is an effective way of improving system spectral efficiency by making use of physical layer network coding. However, energy efficiency in OFDM-based bidirectional relaying with asymmetric traffic requirement has not been investigated. In this study, we focused on subcarrier transmission mode selection, bit loading, and power allocation in a multicarrier single amplified-and-forward relay system. In this scheme, each subcarrier can operate in two transmission modes: one-way relaying and two-way relaying. The problem is formulated as a mixed integer programming problem. We adopt a structural approximation optimization method that first decouples the original problem into two suboptimal problems with fixed subcarrier subsets and then finds the optimal subcarrier assignment subsets. Although the suboptimal problems are nonconvex, the results obtained for a single-tone system are used to transform them to convex problems. To find the optimal subcarrier assignment subsets, an iterative algorithm based on subcarrier ranking and matching is developed. Simulation results show that the proposed method can improve system performance compared with conventional methods. Some interesting insights are also obtained via simulation.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.10a
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• pp.399-402
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• 2017

We consider an sensor partitioning problem for energy-efficient measurement scheduling in a spatially correlated sensor field where sensors are located randomly. We divide the whole sensors into subsets of k sensors in the way of letting each subset give similar amount of mutual information. Then it allows more prolonged life time of the sensor field than measuring the sensors that gives most information only. To this end, we compute the Shapley value of each sensor and compose the subsets so that each subset can have total Shapley value similar with the other subsets.