• Genomics & Informatics
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• v.9 no.4
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• pp.161-172
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• 2011

Angiogenesis is regulated by a large number of molecules and complex signaling mechanisms. The G protein $G{\alpha}_{13}$ is a part of this signaling mechanism as an endothelial cell movement regulator. Gene expression analysis of $G{\alpha}_{13}$ knockout mouse embryos was carried out to identify the role of $G{\alpha}_{13}$ in angiogenesis signaling during embryonic development. Hypoxia-inducible response factors including those acting as regulators of angiogenesis were over expressed, while genes related to the cell cycle, DNA replication, protein modification and cell-cell dissociation were under expressed. Functional annotation and network analysis indicate that $G{\alpha}_{13}{^{-/-}}$ embryonic mice were exposed to hypoxic conditions. The present analysis of the time course highlighted the significantly high levels of disorder in the development of the cardiovascular system. The data suggested that hypoxia-inducible factors including those associated with angiogenesis and abnormalities related to endothelial cell division contributed to the developmental failure of $G{\alpha}_{13}$ knockout mouse embryos.

• Nuclear Engineering and Technology
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• v.54 no.1
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• pp.301-309
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• 2022

This work aims to establish some X-ray qualities recommended by the International Standard Organization (ISO) using the half-value layer (HVL) and H_p(10) dosimetry approaches. The HVL values of the following qualities N-60, N-80, N-100, N-150 and N-250 were determined using various attenuation layers. The obtained results were compared to those of reference X-ray beam qualities and a good agreement was found (difference less than 5% for all qualities). The GAMOS (Geant4-based Architecture for Medicine-Oriented Simulations) radiation transport Monte Carlo toolkit was employed to simulate the production of X-ray spectra. The characteristics HVLs, mean energy and the spectral resolution of simulated spectra have been calculated and turned out to be conform to the ISO reference ones (difference less than the limit allowed by ISO). Furthermore, the conversion coefficients from air kerma to personal dose equivalent for simulated and measured spectra were fairly similar (the maximum difference less than 4.2%).

• Proceedings of the Korean Institute of Building Construction Conference
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• 2021.05a
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• pp.74-75
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• 2021

In the recent 2017 annual average fine dust concentration (PM2.5) statistics released by the Organization for Economic Cooperation and Development (OECD), Korea has a high concentration of 25.14㎍/m3, which is about twice the average of 12.5㎍/m3 in OECD countries. Fine dust (PM2.5) is the main source of secondary pollutant production by the reaction of primary pollutants emitted from automobiles and thermal power plants, mainly composed of sulfates, nitrates, and organic carbon. The permeable block is an eco-friendly product that prevents rainwater from collecting on the surface of the road because it does not penetrate the groundwater properly, and is widely constructed on sidewalks or parking lots to recharge groundwater in case of rain. In addition, the pavement of the permeable block is a fundamental solution to reduce pollution by preventing rainwater from flowing into the stream, and it also has the advantage of easy replacement as well as low replacement costs. Therefore, this study was a basic experiment to produce permeable blocks mixed with TiO2 and diatomite to improve indoor air quality, and intended to analyze the flexural strength and compressive strength of permeable blocks mixed with TiO2.

• Journal of Korean Biological Nursing Science
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• v.25 no.4
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• pp.266-275
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• 2023

Purpose: Although long-term viral suppression and antiretroviral therapy (ART) success depend on sustained adherence, adolescents' adherence rates are suboptimal. Optimal adherence is influenced by various factors. Since Sub-Saharan Africa is home to over 80% of adolescents living with human immunodeficiency virus (HIV) and considering their unique characteristics and susceptibility to poor adherence, it is crucial to provide updated knowledge on adherence rates and their determinants among this population. This review aims to present up-to-date data on adherence rates and associated factors among HIV-positive adolescents in Sub-Saharan Africa. Methods: A systematic review was conducted following the PRISMA guidelines. The PubMed and Scopus databases were used to identify documents corresponding to the study's objectives. Eleven studies were included in this review after being selected from among all studies that were found online from 2017 to 2023. Results: The reported adherence rates ranged from 55% to 86%. In total, 32 factors were found to be related to adherence among HIV-positive adolescents in Sub-Saharan Africa. These included 12 adherence-facilitating factors and 20 adherence-inhibiting factors. The most often mentioned factors affecting adherence were advanced World Health Organization clinical stage (i.e., stage IV), ART dose and regimens, a lack of support, and violence victimization. Conclusion: Our findings can help healthcare providers collaborate with HIV-positive adolescents to improve ART adherence and ensure the best possible health outcomes.

• Journal of Distribution Science
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• v.12 no.12
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• pp.65-73
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• 2014

Purpose - Distribution of agricultural products is collapsing due to recent changes in the environment balance between retailers and producers. Further, the increase in the imports of agricultural products due to free trade has caused revenue problems for producers. Agricultural producers are faced with increasing difficulties, and the organized producing center's importance is growing each day. Korean organized producing centers' policies have been conducted since 2000, and have thus been sustained for more than 10 years. Organizing a producing center's business is focused on agricultural cooperative and farming association corporation this has already have been carried out. In addition, it has achieved significant results through these organizations, but it still has many problems. Research design, data, and methodology - Organized producing centers were classified for each type. The survey covered 90 organizations, based on factor analysis, analysis of balance, and logistic regression analysis. The results of the conducted factor analysis are as follows. Production, marketing, human resources management, organizational skills, post management, safety, and scale were classified as the seven kinds of factors. These are the factors that affect the organized producing centers through the variance analysis and logistic regression analysis. The purpose of such research and analysis is to suggest the direction for the future organized producing centers' policies. Result - Results of the analysis of the variance are listed below. Items by type, production, marketing, human resource management, and organizational skills are shown to depict differences between the factors. Organization form results show that production and marketing showed a difference between the factors. The size of the organization, production, and marketing showed the difference between the factors. The factors affect organized producing centers differently depending on the type shown, as seen from the results. In contrast, the logistic regression results of the analysis are as follows. Considering the results by the type of item, and the horticulture type of marketing, human resource management has a (+) influence. Grain type and production showed a (+) influence. New types of income affecting organizational skills have a (+) influence. Considering the results for each type of organization, the agricultural cooperative type of marketing and human resource management have (+) influence. Farming association corporation type of production has a (+) influence. As a result, the size of the organization is as follows. Large organizations are production, expressed in marketing with a (+) impact. Medium-size organizations are expressed with their size factor having a (+) impact. Small organizations are expressed with a safety factor having a (+) impact. Conclusions - The types of factors display different effects. One factor is that the type of a (+) represents the influence of other factors (-) as per factor symptomatology. Therefore, the type of measures to organize a strategy to maximize the benefits of your organization should be pursued. In addition, based on the support for small organizations, improving the quality of the producer organization should be considered.

• 대한공업교육학회지
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• v.38 no.1
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• pp.1-27
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• 2013

The purpose of this study was to find out the areas and their constitute elements of new apprenticeship through the expert of vocational education to improve the growth potential in the field of industry. Through the three times Delphi research process final composing areas and elements(total 6 areas and 41 sub-elements) of new apprenticeship were extracted. Followings are specific study results of 41 sub-elements for the 6 areas. In area A(Technology Skill aspect) total nine sub-elements were deducted as follows. Technology skill's field appling ability, new technology skill's acquisition, quality assurance ability, research development ability, material management using ability, problem solving ability, core technology skill understanding ability, idea's imagery expressing ability, creative design ability. In area B(Institutional aspect) total five sub-elements were deducted as follows. Flexible human material support, precise division of works, objective result assessment, institutionalization of responsibilities and liabilities between teacher and student, institutionalization of duty invention reward. In area C(Affective aspect) total eight sub-elements were deducted as follows. Manners and cooperation between teacher & student and peer, values for job, basic attitude for technology, job ethic sense, respect of other organization, active action to organization change, attitude of technology successor, service mind. In area D(Self-improvement aspect) total nine sub-elements were deducted as follows. Self evaluation and reflection, cultivate of organization understanding, career planning and developing ability, sound philosophy of life, communication ability, decision making ability, prepare of individual competence enhance system, self-control ability improvement, reaction of unexpected situation. In area E(Knowledge aspect) total four sub-elements were deducted as follows. Basic knowledge of relevant area, knowledge of new technology & preceding technology, fusion and relocation of knowledge, practical knowledge. In area F(Environmental aspect) total six sub-elements were deducted as follows. Awareness of business environment, understanding of education and practice environment, understanding of apprenticeship's business demand, connectivity of region community, adapt ability of labor market's change, awareness of society environment change.

• Korean Journal of Agricultural and Forest Meteorology
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• v.23 no.4
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• pp.235-250
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• 2021

The overarching question of this study is how a typical rice cultivation system in Gimje, Korea was keeping up with the triple-win challenge of climate-smart agriculture (CSA). To answer this question, we have employed (1) quantitative data from direct measurement of energy, water, carbon and information flows in and out of a rice cultivation system and (2) appropriate metrics to assess production, efficiency, GHG fluxes, and resilience. The study site was one of the Korean Network of Flux measurement (KoFlux) sites (i.e., GRK) located at Gimje, Korea, managed by National Academy of Agricultural Science, Rural Development Administration. Fluxes of energy, water, carbon dioxide (CO₂) and methane (CH₄) were directly measured using eddy-covariance technique during the growing seasons of 2011, 2012 and 2014. The production indicators include gross primary productivity (GPP), grain yield, light use efficiency (LUE), water use efficiency (WUE), and carbon uptake efficiency (CUE). The GHG mitigation was assessed with indicators such as fluxes of carbon dioxide (F_CO2), methane (F_CH4), and nitrous oxide (F_N2O). Resilience was assessed in terms of self-organization (S), using information-theoretic approach. Overall, the results demonstrated that the rice cultivation system at GRK was climate-smart in 2011 in a relative sense but failed to maintain in the following years. Resilience was high and changed little for three year. However, the apparent competing goals or trade-offs between productivity and GHG mitigation were found within individual years as well as between the years, causing difficulties in achieving the triple-win scenario. The pursuit of CSA requires for stakeholders to prioritize their goals (i.e., governance) and to practice opportune interventions (i.e., management) based on the feedback from real-time assessment of the CSA indicators (i.e., monitoring) - i.e., a purpose-driven visioneering.

• Journal of the Korean Society for information Management
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• v.25 no.1
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• pp.5-17
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• 2008

The purpose of this paper is to identify the usefulness of Weblog genre analysis in knowledge creation within an organization where communications are occurred frequently among the employees with information and communication technologies (ICTs). Knowledge creation is essential to achieve competitive advantage in today's knowledge-oriented working environments. There has been huge investment on knowledge management systems to achieve such advantages. It is, however, widely recognized that distributed knowledge management systems often fail due to the different social contexts across the sub-organizations where the local information systems are deployed. It is important to coordinate such social gaps across the sub-organizations to achieve better advantages. Given that Weblogs users often feel a shared social norm. Weblogs playa positive role of narrowing the social gaps. This paper argues that the genre analysis of Web logs could provide important clues to narrow the social gaps existed across the sub-organizations within an organization. Hence, such taxonomical practice may be a solution for the high rate of failure in knowledge management system implementations in an organization. This paper uses the theory of organizational knowledge creation (Nonaka & Takeuchi. 1995) and social construction of technology (SCOT) approach (Bijker, 1995) to compare the socialized with the non-socialized integration of distributed information systems. The findings of this research provide a useful framework for better implementing knowledge management practices especially in distributed working environments.

• Journal of Korean Society of Rural Planning
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• v.18 no.2
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• pp.13-26
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• 2012

This study aims to present the policy issues and direction of sub-urban residential complex by analyzing the settlement environment and life satisfaction. For the purpose, 10 sub-urban residential complexes in Chungnam Province were surveyed for general situation, physical environment, social environment, economic environment. The results are as follows; 1) The satisfaction in the physical environment is more higher in case of the complex created by the public organization. 2) The physical environment is an important factor in the determinant of the settlement, while the economic environment have a relatively lower impact. 3) The residents community is the more active, the satisfaction in the social environment is the more improved. 4) The source of income or the activity of consumption doesn't have an effect on the satisfaction in the economic environment. On the basis of this study, three programs for improvement of sub-urban residential complex policy were suggested. First, the various information and counseling service should be provided to attract city dwellers. Second, the policy on the development of sub-urban residential complex has to consider residential preference factors and improve the quality of life. Third, to increase the life satisfaction, the residents community should be activated and especially the activation of community with residents in other village is very important.

• The Journal of the Korea Contents Association
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• v.17 no.4
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• pp.285-293
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• 2017

Although there have been continued researches on the effect of fatigue among organization members on organizations, there has been an absence of studies on sub-factors of organizational commitment using Saito(1999)'s whole questionnaire. Therefore, this study aimed to measure the level of fatigue among police officers and empirically examine the effect of fatigue on organizational commitment. Based on the previous studies, fatigue(mental fatigue and physical fatigue) of police officers and physical disharmony were selected as independent variables, and organizational commitment(affective commitment, continuance commitment and normative commitment) was selected as a dependent variable. The meanings and the implications of this study are as follows. First, from a theoretical perspective, this study has significance as the first study, which used Saito(1999)'s whole scale and examined the relationship between sub-variables of organizational commitment in a police organization. This study also confirms the importance of fatigue management for organization managers. Second, from a perspective of organization management, this study implies that effort should be made to measure fatigue of police officers, who have 5 to 10 years of service and work as Senior patrol and sergeants and manage it actively on an organizational level, and there is a need to develop a training program for improving their attitudes towards organizations.