• Korean Journal of Materials Research
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• v.1 no.2
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• pp.86-92
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• 1991

A potential energy function comprising a two-body potential term which is modified form Morse potential and a three-body potential term which is modified from Axilrod-Teller potential has been developed for small carbon clusters. The structural changes of small carbon clusters $C_2-C_6$ are qualitatively investigated by employing this potential energy function representing the energies of the small carbon cluster isotopes as a function of the three body intensity factor. It is found that the structure of the small carbon cluster changes from open structure to closed one, from complicated structure to simple one, and from three-dimensional structure to two-or-one dimensional one as the degree of the three-body interaction increases.

• Journal of IKEEE
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• v.27 no.1
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• pp.93-102
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• 2023

As one of the techniques for analyzing malicious code, techniques creating a sequence or a graph of function call relationships in an executable program and then analyzing the result are proposed. Such methods generally study function calling in the executable program code through static analysis and organize function call relationships into a sequence or a graph. However, in the case of an obfuscated executable program, it is difficult to analyze the function call relationship only with static analysis because the structure/content of the executable program file is different from the standard structure/content. In this paper, we propose a dynamic analysis method to analyze the function call relationship of an obfuscated execution program. We suggest constructing a function call relationship as a graph using the proposed technique.

• Journal of Korean Biological Nursing Science
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• v.16 no.1
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• pp.17-25
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• 2014

Purpose: The purpose of this study was to review the curriculum on biological nursing: structure and function of the human body, clinical microbiology, pathophysiology, and function and effect of drugs. Methods: Data was collected by searching and reviewing internet websites of 102 nursing schools or universities which provide 4 years nursing education in the Republic of Korea. The 74 curriculum on biological nursing science were available and analyzed by title, credits, hours, types of major (core or selective), offering semester, and laboratory practice. Results: The titles of 4 courses were diverse and were offered as core major (core requisites) or selective major. Structure and function of human body was offered in priority with more credits. Laboratory practice was poorly established in most courses. Biological nursing science courses were mostly taught in the second semester of the first year and the first or second semester of second year nursing education courses. Conclusion: There is a need to standardize the curriculum on biological nursing science and to expand the use of titles proposed by academic society. Also further research is necessary to identify curriculum details and to reflect the needs of professors.

• BMB Reports
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• v.45 no.8
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• pp.427-432
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• 2012

Primary cilia, single hair-like appendage on the surface of the most mammalian cells, were once considered to be vestigial cellular organelles for a past century because of their tiny structure and unknown function. Although they lack ancestral motility function of cilia or flagella, they share common ground with multiciliated motile cilia and flagella on internal structure such as microtubule based nine outer doublets nucleated from the base of mother centrioles called basal body. Making cilia, ciliogenesis, in cells depends on the cell cycle stage due to reuse of centrioles for cell division forming mitotic spindle pole (M phase) and assembling cilia from basal body (starting G1 phase and maintaining most of interphase). Ciliary assembly required two conflicting processes such as assembly and disassembly and balance between these two processes determines the length of cilia. Both process required highly conserved transport system to supply needed substance to grow tip of cilia and bring ciliary turnover product back to the base of cilia using motor protein, kinesin and dynein, and transport protein complex, IFT particles. Disruption of ciliary structure or function causes multiple human disorder called ciliopathies affecting disease of diverse ciliated tissues ranging from eye, kidney, respiratory tract and brain. Recent explosion of research on the primary cilia and their involvement on animal development and disease attracts scientific interest on how extensively the function of cilia related to specific cell physiology and signaling pathway. In this review, I introduce general features of primary cilia and recent progress in understanding of the ciliary length control and signaling pathways transduced through primary cilia in vertebrates.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.29B no.8
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• pp.24-34
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• 1992

A process control language is developed using function block configuration, to simplify software development for large scale process control systems, and to implement advanced control algorithms with ease. A function block parser and controller is implemented to be suitable for multi-loop control systems having hierachical structure. On-line change of controller parameter is possible, and inclusion of user defined function block is also possible. By adding plant model block, control performance can be checked in advance. Function blocks of the Smith Predicotor, auto-tuners are implemented to demonstrate usefulness of function block configuration.

• Journal of Power System Engineering
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• v.7 no.4
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• pp.38-43
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• 2003

This paper proposes an optimum design problem of structural and control systems. taking a 3-D truss structure as an example. The structure is supposed to be subjected to initial static loads and time-varying disturbances. The structure is controlled by a state feedback $H_{\infty}$ controller to suppress the effect of the disturbances. The design variables are the cross sectional areas of truss members. The structural objective function is the structural weight. As the control objective, we consider two types of performance indices. The first function represents the effect of the initial loads. The second one is the norm of the feedback gain. These objective functions are in conflict with each other. Then, first, two control objective functions are transformed into one control objective by the weighting method. Next, the structural objective is treated as the constraint. By introducing the second control objective which considers the magnitude of the feedback gain, we can per limn the design which is robust in modeling errors.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.2
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• pp.153-159
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• 2004

A control-structure combined optimal design problem is discussed taking a 3-D truss structure as a design object. We use descriptor forms for a controlled object and a generalized plant because the structural parameters appear naturally in these forms. We consider not only minimum weight design problem for structure system, but also suppression problem of the effect of disturbances for control system as the purpose of the design. By minimizing the linear sum of the normalized structural objective function and control objective function, it is possible to make optimal design by which the balance of the structural weight and the control performance is taken.

• Proceedings of the KSME Conference
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• 2000.11a
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• pp.402-406
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• 2000

Strain energy function of the isoprene rubber was accurately determined by the experiments of uniaxial tension, planar tension, biaxial tension and volumetric compression. Deformation behavior of alternatively laminated structure of elastomer and reinforced aluminium layers, was analysed by Finite Element method. As a result, Ogden strain energy function obtained from the experiments describes the hyperelastic characteristics of the rubber very well. The compressibility of the rubber reduces axial stiffness of the structure. The axial stiffness of alternatively laminated structure being larger than shear stiffness. Which enables the structure to be shear-deformed easily.

• Interdisciplinary Bio Central
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• v.2 no.3
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• pp.8.1-8.5
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• 2010

Introduction: Recently identified human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Bioinformatics study of hABH2 and hABH3 had led to the discovery of a novel DNA repair mechanism. Very little is known about structure and function of hABH4, one of the members of this superfamily. Therefore, in present study we are intended to predict its structure and function through various bioinformatics tools. Materials and Methods: Modeling was done with modeler 9v7 to predict the 3D structure of the hABH4 protein. This model was validated with the program Procheck using Ramachandran plot statistics and was submitted to PMDB with ID PM0076284. The 3d2GO server was used to predict the functions. Residues at protein ligand and protein RNA binding sites were predicted with 3dLigandSite and KYG programs respectively. Results and Discussion: 3-D model of hABH4, ALKBH4.B99990003.pdb was predicted and evaluated. Validation result showed that 96.4 % residues lies in favored and additional allowed region of Ramachandran plot. Ligand binding residues prediction showed four Ligand clusters, having 24 ligands in cluster 1. Importantly, conserved pattern of Glu196-X-Pro198- Xn-His254 in the functional domain was detected. DNA and RNA binding sites were also predicted in the model. Conclusion and Prospects: The predicted and validated model of human homologue hABH4 resulted from this study may unveil the mechanism of DNA damage repair in human and accelerate the research on designing of appropriate inhibitors aiding in chemotherapy and cancer related diseases.

• Journal of Institute of Control, Robotics and Systems
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• v.7 no.10
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• pp.812-818
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• 2001

This paper proposes an optimum design method of structural and control systems, taking a 2-D truss structure as an example. The structure is supposed to be subjected to initial static loads and disturbances. For the structure, a FEM model is formed, and using modal transformation, the equation of motion is transformed into that of modal coordinates in order to reduce the D.O.F. of the FEM model. The structure is controlled by an output feedback $H^$\infty$$ controller to suppress the effect of the disturbances. The design variables of the simultaneous optimal design of control-structure systems are the cross sectional areas of truss members. The structural objective function is the structural weight. The control objective function is the $H^$\infty$$ norm, that is, the performance index of control. The second structural objective function is the energy of the response related to the initial state, which is derived from the time integration of the quadratic form of the state in the closed-loop system. In a numerical example, simulations have been carried out. Through the consideration of structural weight and $H^$\infty$$ norm, an advantage of the simultaneous optimum design of structural and control systems is shown. Moreover, while the optimized performance index of control is almost kept, we can acquire better design of structural strength.