• Title/Summary/Keyword: Strength Gain

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Gintonin-enriched fraction protects against sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy in high-fat diet-fed mice

  • Jin, Heegu;Oh, Hyun-Ji;Nah, Seung-Yeol;Lee, Boo-Yong
    • Journal of Ginseng Research
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    • v.46 no.3
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    • pp.454-463
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    • 2022
  • Background: Gintonin-enriched fraction (GEF), a non-saponin fraction of ginseng, is a novel glycolipoprotein rich in hydrophobic amino acids. GEF has recently been shown to regulate lipid metabolism and browning in adipocytes; however, the mechanisms underlying its effects on energy metabolism and whether it affects sarcopenic obesity are unclear. We aimed to evaluate the effects of GEF on skeletal muscle atrophy in high-fat diet (HFD)-induced obese mice. Methods: To examine the effect of GEF on sarcopenic obesity, 4-week-old male ICR mice were used. The mice were divided into four groups: chow diet (CD), HFD, HFD supplemented with 50 mg/kg/day GEF, or 150 mg/kg/day GEF for 6 weeks. We analyzed body mass gain and grip strength, histological staining, western blot analysis, and immunofluorescence to quantify changes in sarcopenic obesity-related factors. Results: GEF inhibited body mass gain while HFD-fed mice gained 22.7 ± 2.0 g, whereas GEF-treated mice gained 14.3 ± 1.2 g for GEF50 and 11.8 ± 1.6 g for GEF150 by downregulating adipogenesis and inducing lipolysis and browning in white adipose tissue (WAT). GEF also enhanced mitochondrial biogenesis threefold in skeletal muscle. Furthermore, GEF-treated skeletal muscle exhibited decreased expression of muscle-specific atrophic genes, and promoted myogenic differentiation and increased muscle mass and strength in a dose-dependent manner (p < 0.05). Conclusion: These findings indicate that GEF may have potential uses in preventing sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy.

Electrodeposition onto the Surface of Carbon Fiber and its Application to Composites(I) - Electrodeposition of MVEMA and EMA (탄소섬유 표면에의 고분자 전착과 복합재료 물성(I) - MVEMA와 EMA의 전착 -)

  • Kim, Minyoung;Kim, Jihong;Kim, Wonho;Kim, Booung;Hwang, Byungsun;Choi, Youngsun
    • Applied Chemistry for Engineering
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    • v.9 no.6
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    • pp.894-900
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    • 1998
  • An interphase between carbon fiber and epoxy matrix was introduced to increase impact strength of carbon fiber reinforced composites (CFRC) without sacrificing the interlaminar shear strength. Flexible polymers, I. e., MVEMA (poly(methyl vinyl ether-co-maleic anhydride)) and EMA(poly(ethylene-co-maleic anhydride)), which have reactive functional groups were considered as interphase materials. Weight hain of MVEMA and EMA onto the surface of carbon fibers was evaluated by changing the parameters of electrodeposition process. Electrodeposition mechanism of polymers which have anhydride functional group was identified by IR spectroscopy, that is, the generation of $RCOO^-$ functional group by the attack of hydroxide anion in the basic solution was observed. The weight gain was increased by increasing concentration of polymers, current density, and electrodeposition time. However the excess generation of oxygen gas decreased the weight gain by removing the deposited polymers. Washing in the running water easily removed the deposited polymers which are on the fiber surface without bonding, as a results, only 0.5 wt% of deposited polymers are remained.

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The Execution and Estimation of Construction Cost of High Fluidity Concrete Applying Flowing Concrete Method (유동화공법에 의해 제조한 고유동 콘크리트의 시공 및 원가분석)

  • Han, Min-Cheol
    • Journal of the Korea Institute of Building Construction
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    • v.4 no.2
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    • pp.129-136
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    • 2004
  • High fluidity concrete(HFC) requires high dosage of superplasticizer to acquire sufficient fluidity, and high contents of fine powder and viscosity enhancing admixtures to resist segregation. The use of high amount of admixtures to make HFC at batcher plant in ready mixed concrete company is one of the reasons to raise the manufacturing cost of HFC. For this reason, new type of manufacturing method of HFC are described using both flowing concrete method and segregation reducing superplasticizer(SRS) in order to gain economical profit and offer the convenience for quality control.. As dosage of melamine based superplasticizer increases, it shows that fluidity and bleeding increase, while air contents and ratio of segregation resistance decrease. It also shows that addition of viscosity agent into superplasticizer reduce bleeding and improve segregation resistance of concrete. Dosage of AE agent into superplasticizer containing viscosity agent recovers loss of air contents during flowing procedure. Combination of proper contents of superplasticizer, viscosity agent and AE agent make possible to develope segregation reducing type superplasticizer. Compressive strength of high fluidity concrete applying flowing method with it is higher than that of base concrete. No differences of compressive strength between compacting methods are found. For the estimation of construction cost of high fluidity concreting using segregation reducing type superplasicizer, under same strength levels, although material cost of high fluidity concrete is somewhat higher than that of plain concrete due to segregation reducing type superplasticizer cost, labor cost and equipment cost of high fluidity concrete is cheaper than that of plain concrete. However, based on the strength differences, high fluidity concrete shows lower material cost, labor cost and equipment cost than that of plain concrete due to decreasing in size of member and re-bar caused by high strength development of concrete.

Structural Stability of Temporary Facility System using High-Strength Steel Pipes Based on Abnormal Behavior Parameters (이상거동 변수 기반 고강도 강관 가시설 시스템의 구조 안정성)

  • Lee, Jin-Woo;Noh, Myung-Hyun;Lee, Sang-Youl
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.1
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    • pp.1-12
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    • 2019
  • This study defined abnormal behaviors such as bending deformations or buckling behaviors occurred in high strength steel pipe strut system, and carried out a full-scale bending test for different connection types. A parametric study was carried out to gain an insight about structural performances considering abnormal behavior effects in high strength steel pipe strut system. Five abnormal behaviors were considered as undesirable deflections of strut structures, which are basic load combination, excessive excavation situations, impact loading effects, additional overburden loads, load combinations, and strut lengths. Subsequent simulation results present various influences of parameters on structural performances of the strut system. Based on the results, we propose methods to prevent unusual behaviors of pipe-type strut structures made of high strength steels.

A Review of Physical Properties of Cement-Free Precast Concrete Using Industrial By-Products (산업부산물을 적용한 무 시멘트 프리캐스트 콘크리트의 물리적 특성 검토)

  • Jung, Young-Woong;Yun, Ja-Yeon;Shin, Kyung-Su;Lee, Taegyu;Choi, Hyeonggil
    • Journal of the Korea Institute of Building Construction
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    • v.24 no.3
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    • pp.309-318
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    • 2024
  • This research investigated the feasibility of incorporating industrial by-products into precast concrete formulated with blast furnace slag and natural gypsum. Specifically, the study examined the effects of incorporating steelmaking slag(STS slag), combined heat power plant fly ash, and return dust. The optimal amount of these by-products was determined by measuring air content, slump, and compressive strength at various incorporation levels. Results demonstrated that compressive strength was enhanced across all levels of by-product addition. Notably, incorporating 10% of the by-products led to exceptional early-age strength development. However, a 20% addition of combined heat power plant ash significantly reduced the slump value by approximately 40%. Considering these findings and the requirement for rapid strength development in precast concrete applications, a 10% incorporation of industrial by-products was deemed optimal due to its ability to accelerate early-age strength gain.

The Effects of Dietary Lipids and Ovariectomy on Bone Mass in Rats (식이지방과 종류와 난소절제가 흰쥐가 골질량에 미치는 양향)

  • 안혜선
    • Journal of Nutrition and Health
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    • v.32 no.1
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    • pp.3-9
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    • 1999
  • This study examined the effect of dietary lipids and ovariectomy(OVX) on bone mass in rats. The experimental animals were divided into sham operation(S) or OVX(O) groups and then each group was divided into soybean oil(SS, OS), beef tallow(SB, OB), and fish oil(SF, OF) diet group. Experimental diets were fed for 16 weeks. Weight gain tended to be higher in OVX groups than in sham groups. Weigth gain was the highest in beef tallow group (SB) and the lowest in fish oil group(SF). There were no difference in weight, length, breaking force, strength and circumference of femur mong groups. However, volume of femur tended to be higher in OVX groups than in sham groups. Ash content of femur was significantly lower in OVX than sham groups but there were no difference between SB and OB group. Ca content in the soybean oil and beef tallow group were not influenced by OVX but Ca content in fish oil group was significantly higher in OF than SF group. The SB group showed the hyighest Ca content and the SF group showed the lowest Ca content. P content of femur was significantly lower in OVX groups than in sham groups but there were no difference between SB and OB group. The SS group showed the highest P content and the OS and OF group showed lower P content compare to other groups. From this result, it suggested that beef tallow positively influenced maintenance of bone mass by means of accumulation of body fat in ovariectomy.

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The multipath propagation loss analysis of dynamic telemetry link using the 3D antenna pattern (3차원 안테나 패턴을 사용한 동적 원격측정링크의 다중경로 전파손실 분석)

  • Kim, Kyun-Hoi;Shin, Seok-Hyun;Koh, Kwang-Ryul;Yun, Jung-Kug
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.39 no.3
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    • pp.254-260
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    • 2011
  • Telemetry link is dynamic communication link that antenna gain and polarization are varying with the movement of the airplane. In this paper we calculated the antenna gain, polarization mismatch using the flight trajectory, motion of the airplane and 3D antenna pattern. And we modeled the multipath environment to the 2-Ray spherical earth reflection geometry, estimated the received signal strength when the narrow beam antenna received the RF signal transmitted from the airplane. Also we performed the flight test and after comparing measured value with the estimated value, we confirmed to almost coincide with each other.

A Study on Strategic Alliances of the Korean Fashion Industries (한국 패션유통기업의 전략적 제휴 활용에 관한 연구)

  • Moon Sook Kim;Yu-Jin Jeon
    • The Research Journal of the Costume Culture
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    • v.8 no.1
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    • pp.15-29
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    • 2000
  • Nowadays every part no company continues to gain the upper hand of a competitive superiority. Strategic Alliances between companies have been rapidly increased to preoccupy a market. The purpose of this study is to find devices of strategic alliances for the competitive distribution environment of Korean fashion industries. This reseach has been done by the literature review of the related articles, books, and the case studies in domestic markets as well as foreign ones. Strategic alliances are business relationships established by tow or more companies which cooperate out of mutual need and share risk in achieving a common objective. Today the purpose of international strategic alliances is to be competitive in global markets by meeting of exceeding new standards for products and technology use. Various types of alliances are occurred and this situation will be more common and generalized since one parter's weakness is offset by the other's strength. Strategic alliances are characterized by being horizontal, collaborative, and mutually beneficial to all parties. When used in good faith, the strengths gained in a strategic alliance are great. Therefore retailer should find that to gain faithful partners is important and should effort positively to enrich alliances based on a mutual belief. Finally, to become a company for leading the global market, it is necessary that we operate strategic alliances mixed foreign investments and domestic technology with local distributions.

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Heat Resistance Properties of Thin Section HiSiMo Ductile Iron for Exhaust Manifold (배기 매니폴드용 박육 고규소 구상흑연주철의 내열 특성)

  • Lee, Do-Kyung;Kim, Sung-Gyu;Lee, Byung-Woo
    • Journal of Power System Engineering
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    • v.17 no.4
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    • pp.109-114
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    • 2013
  • In this study, the microstructure, mechanical properties and high temperature oxidation characteristics of HiSiMo and HiSiMoM ductile iron for exhaust manifold were investigated. The HiSiMoM ductile iron was developed by optimization of alloying element addition and casting design. The exhaust manifold prototype was fabricated using the HiSiMoM iron and this resulted in the weight saving of 0.73kg. The microstructures of the HiSiMo and HiSiMoM irons were similar each other and graphite nodularity was 89% and 93% respectively. Tensile strengths of them were 663.5 and 674.4 MPa and Brinell hardness were 235.3 and 243.9 respectively. Both irons showed parabolic weight gain behavior in high temperature oxidation atmosphere. Oxidation layer was divided into external and internal layers. The weight gain of the HiSiMoM iron was lower than that of the HiSiMo iron after isothermal oxidation test at $900^{\circ}C$. This should be rationalized by higher Si enrichment at the interface of the matrix and internal layer of the HiSiMoM iron.

A Thought on the Fire Fighting Official Selection Examination (소방공무원 채용시험에 관한 소고)

  • Hyun Seong-Ho;Song Yun-Suk;Lee Chang-Woo
    • Fire Science and Engineering
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    • v.19 no.4 s.60
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    • pp.80-86
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    • 2005
  • Fire fighting officials perform their works in the field and in most cases, undergo circular appointments for their service period. If they don't gain experience in field works, they have difficulty in performing faithful planning or administrative works. So they surely have to gain experiences in field works. Like this, fire fighting officials' works comprise a lot of fields, comparing with other job workers. So they need a strict body condition. The aim of this inquiry is to scrutinize body standards and important roles concretely which are necessary to fire fighting officials, to analyze written examination, physical test, physical strength test, and interview examination, and to establish the proposal which is necessary to improvement.