• 한국광학회:학술대회논문집
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• 한국광학회 2004년도 하계학술발표회
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• pp.146-147
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• 2004

• 대한의용생체공학회:의공학회지
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• 제26권1호
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• pp.55-63
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• 2005

A novel imaging system for High-resolution Ultrasonic Transmission Tomography (HUTT) and soft tissue differentiation methodology for the HUTT system are presented. The critical innovation of the HUTT system includes the use of sub-millimeter transducer elements for both transmitter and receiver arrays and multi-band analysis of the first-arrival pulse. The first-arrival pulse is detected and extracted from the received signal (i.e., snippet) at each azimuthal and angular location of a mechanical tomographic scanner in transmission mode. Each extracted snippet is processed to yield a multi-spectral vector of attenuation values at multiple frequency bands. These vectors form a 3-D sinogram representing a multi-spectral augmentation of the conventional 2-D sinogram. A filtered backprojection algorithm is used to reconstruct a stack of multi-spectral images for each 2-D tomographic slice that allow tissue characterization. A novel methodology for soft tissue differentiation using spectral target detection is presented. The representative 2-D and 3-D HUTT images formed at various frequency bands demonstrate the high-resolution capability of the system. It is shown that spherical objects with diameter down to 0.3㎜ can be detected. In addition, the results of soft tissue differentiation and characterization demonstrate the feasibility of quantitative soft tissue analysis for possible detection of lesions or cancerous tissue.

• Journal of the Optical Society of Korea
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• 제15권2호
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• pp.111-117
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• 2011

Full-range spectral domain optical coherence tomography (SD-OCT) with a 1-${\mu}m$ band light source is shown here. The phase of the reference beam is continuously stepped while the probing beam scans the sample laterally (B-scan). The two dimensional spectral interferogram obtained is processed by a Fourier transform method to obtain a complex spectrum leading to a full-range OCT image. A detailed mathematical explanation of the complex conjugate resolving method utilized is provided. The system's measurement speed was 7.96 kHz, the measured axial resolution was $9.6{\mu}m$ in air and the maximum sensitivity 99.4 dB. To demonstrate the effect of mirror image elimination, In vivo human eye pathology was measured.

• Current Optics and Photonics
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• 제7권1호
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• pp.73-82
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• 2023

In this study, we demonstrate ultrahigh-resolution spectral-domain optical coherence tomography with a 200-kHz line rate using a superluminescent diode with a -3-dB bandwidth of 100 nm at 849 nm. To increase the line rate, a subset of the total number of camera pixels is used. In addition, a partial-spectrum detection method is used to obtain OCT images within an imaging depth of 2.1 mm while maintaining ultrahigh axial resolution. The partially detected spectrum has a flat-topped intensity profile, and side lobes occur after fast Fourier transformation. Consequently, we propose and apply the super-Gaussian window function as a new window function, to reduce the side lobes and obtain a result that is close to that of the axial-resolution condition with no window function applied. Upon application of the super-Gaussian window function, the result is close to the ultrahigh axial resolution of 4.2 ㎛ in air, corresponding to 3.1 ㎛ in tissue (n = 1.35).

• Korean Journal of Radiology
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• 제22권1호
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• pp.86-96
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• 2021

CT is a diagnostic tool with many clinical applications. The CT voxel intensity is related to the magnitude of X-ray attenuation, which is not unique to a given material. Substances with different chemical compositions can be represented by similar voxel intensities, making the classification of different tissue types challenging. Compared to the conventional single-energy CT, spectral CT is an emerging technology offering superior material differentiation, which is achieved using the energy dependence of X-ray attenuation in any material. A specific form of spectral CT is dual-energy imaging, in which an additional X-ray attenuation measurement is obtained at a second X-ray energy. Dual-energy CT has been implemented in clinical settings with great success. This paper reviews the theoretical basis and practical implementation of spectral/dual-energy CT.

• Journal of the Optical Society of Korea
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• 제14권1호
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• pp.49-54
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• 2010

In this study, the use of a continuous-wave (CW) supercontinuum (SC) seeded by an erbium-doped fiber's amplified spontaneous emission (ASE) for optical-coherence tomography imaging is experimentally demonstrated. It was shown, by taking an in-depth image of a human tooth sample, that due to the smooth, flat spectrum and long-term stability of the proposed CW SC, it can be readily applied to the spectral-domain optical-coherence tomography system. The relative-intensity noise level and spectral bandwidth of the CW SC are also experimentally analyzed as a function of the ASE beam power.

• Korean Journal of Radiology
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• 제24권10호
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• pp.947-948
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• 2023

• Journal of the Optical Society of Korea
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• 제7권4호
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• pp.216-223
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• 2003

We report a technique that improves the spatial resolution of optical coherence tomography (OCT) by utilizing fiber-based spectral filtering. The proposed technique improves the resolution by filtering out the erbium’s characteristic peak from the amplified spontaneous emission (ASE) source spectrum, and reshaping the spectrum to Gaussian-like. We used a long period fiber grating (LPG) and an erbium doped fiber (EDF) absorber for the spectral filtering. An in-house made ASE source as well as a commercial ASE source [ASE-FL7002] was used as the OCT sources to study the proposed technique. The resolution of the OCT based on an in-house made ASE source is enhanced from 200 to 40 ㎛ with an LPG. While, the resolution of the OCT based on a commercial ASE source is enhanced from 25 to 19 ㎛ with the aid of an EDF absorber. However, sidelobes still exist in the interferogram due to imperfect spectral filtering, which limited the resolution. Further enhancement in the spatial resolution of the OCT system using the ASE source is possible with the aid of cascaded LPGs and/or carefully designed EDF absorber.

• 한국광학회:학술대회논문집
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• 한국광학회 2009년도 동계학술발표회 논문집
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• pp.169-170
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• 2009

We present a quantification protocol to get the alignment factors of a custom-made spectrometer and the nonlinear fitting function between the measured CCD pixel domain and the wavelength domain to apply the spectral-domain optical coherence tomography using fiber Bragg gratings. We have used 4 different center wavelength gratings with a narrow spectral bandwidth (<0.05 nm) and the same reflectivity (>92 %) to calibrate and align the custom-made spectrometer.

• 한국광학회:학술대회논문집
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• 한국광학회 2005년도 하계학술발표회
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• pp.180-181
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• 2005