• 한국식품위생안전성학회지
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• 제33권5호
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• pp.361-368
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• 2018

니트로사민은 산성이나 열을 가했을 때 2급 아민과 질소산화물이 반응해서 생성되는 발암물질이다. 일반적으로 위해 물질에 대한 안전성평가는 그 노출량을 mg/kg body weight/day로 산출하여 독성기준치와 비교하는 방법을 사용한다. 이런 방법은 정책 근거자료로는 적합하나 소비자들에게 식생활 정보로 제공하기에 미진한 부분이 있다. 따라서 주재료 및 조리법으로 분류한 음식군에 대한 NDMA(N-nitrosodimethylamine), NDBA (N-nitrosodibutylamine) 및 6종 니트로사민(NDMA, NDBA, NDEA (N-nitrosodiethylamine), NPYR (N-nitrosopyrrolidine), NPIP (N-nitrosopiperidine), NMOR (N-nitrosomorpholine) 함량 분포를 파악하여 식습관 교육에 도움을 주고자 본 연구를 실시하였다. 2014~2016년 국민건강영양조사 24시간 회상법 자료를 사용하여 만 7세 이상을 연구 대상으로 음식별 레시피와 섭취량을 추출하였고, 2013~2015년 총식이조사 원자료를 바탕으로 음식 한끼니 제공량 내 니트로사민 함량 분포를 R프로그램으로 산출하였다. 볼락, 장어, 멸치 육수, 명태 등의 기여로 어패류 및 해조류를 주재료로 한 음식군은 섭취량과 상관없이 NDMA, NDBA 및 총 6종 니트로사민 모두에 대한 노출을 높이는 것으로 나타났다. 또한 조리법에 따른 분류에서는 국 및 탕류와 찌개 및 전골류가 가장 크게 노출에 기여하는 것으로 나타났다. 곡류, 과실류 및 유제품류 주재료 음식군, 밥류 및 밥 외의 다른 재료를 부가한 음식군들의 니트로사민 노출에 대한 기여도는 매우 낮은 것으로 나타났다. 니트로사민의 경우 조리시 생성되는 여타 화합물과는 달리 국, 탕, 찌개, 전골 등 끓임을 주로 하는 음식과 어패류를 주재료로 하는 음식에서의 기여율이 매우 높은 것으로 나타났으며, 이는 기존에 가공육류를 니트로사민의 주노출원으로 생각하던 것과는 매우 큰 차이를 보인다.

• 한국동물위생학회지
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• 제42권4호
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• pp.193-200
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• 2019

Blood test is a useful tool in establishing medical treatment for livestock. It provides information such as disease diagnosis, treatment effects, prognostic judgment, and health status. This study compared the value of erythrocytes and leukocytes among conventional, transgenic miniature, and transgenic conventional pigs aged six months to 24 months. Further, it analyzed the aspects of hematological value changes according to the pigs' ages. As a result, the number of red blood cells (RBC), which include hemoglobin, and hematocrit, and the number of white blood cells (WBC), which include neutrophils, and lymphocyte, were high among transgenic miniature pigs, compared with the conventional and transgenic conventional pigs. Conventional pigs showed similar values of RBC and WBC regardless of transgenesis. In comparing their age, the RBC decreased as the age increased compared with the pigs among all the three groups aged of 6~12 months. On the other hand, WBC and neutrophils showed no significant difference regardless of different ages among all the three groups. However, various counts in RBC and WBC were mostly found to be higher in each age in transgenic miniature pigs than in conventional and transgenic conventional pigs. The results of this study show that the values of RBC and WBC were generally higher in transgenic miniature pigs than in conventional and transgenic conventional pigs. Based on this research, hematological values can be widely used in diagnosing diseases or checking the health status of transgenic pigs that are used as disease models, organ transplant source and alike.

• 지역사회간호학회지
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• 제9권2호
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• pp.482-501
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• 1998

As an initial step toward the improvement of sexual education in middle school students, a survey on sexual attitudes and experience was done in Kangwon - Do, Korea. Questionnaires consisted of 68 items distributed to 240 boys and 240 girls from November 1 to December 20, 1996. Answers from 420 students were subjected to an analysis with SPSS. 92.4% of the girls experienced menstruation. Of them, 74.0% showed a negative reaction. 52.0% of the boys experienced night ejaculation. Of them, 81. 7% showed a negative reaction. Boys (64.3%) masturbated more than girls (17. 6%) (p= 0.0000). The understanding of masturbation was higher in boys than in girls (p = 0.0000). 87.2% of the subjects wished meetings with the opposite sex. During the meeting with the opposite sex, 12.9% of the students enjoyed drinking or smoking, 8.8% had intercourse. Boys(91.9%) watched pornography or porno-video more than girls(40.5%)(p=0.0000). 83.3% of the girls thought that both males and females should keep their virginity untill marriage. However, only 48.6% of boys thought that(p=0.0000). Of boys who had experienced sexual touch, 34.8% had intercourse. Of the 30 students(26 boys, 4 girls) who experienced sexual intercourse, 22 students had partners of the opposite sex and were friends. First intercourse 63.4% of these students had their in middle school period. The frequencys of sexual intercourse (more than 6times) was written by 12 students (40.0%). 24 students(16 boys and 8 girls) experienced sexual violence. As for dealing with sexual violence, 14 suffered by him or herself whill 7 students discussed it with a friend. There was a significant difference in the sources of information between boys and girls(p= 0.000), 36.0% had learned from an official sexual education source, usually from school nurses (74.0%). 92.6% of the students thought that sexual education was necessary. They believed that the appropriate person for sexual education was from a school nurse (53.1%) or from parents (19.5%). According to the above results, the following might be suggested: Realistic and future-directed sexual education material should be developed : Education programs to improve students insight and control sexual desire should be prepared: a systematic approach to activate the role of school nurse in sexual education should be prepared.

• 한국식품영양학회지
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• 제25권4호
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• pp.842-849
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• 2012

본 연구는 구멍쇠미역을 대상으로 건강기능성식품의 소재로의 활용을 위한 가능성을 타진하고자 영양성분 분석을 통한 식품영양학적 접근 및 생리활성 기능을 분석하였다. 식품 영양학적 접근에서의 구멍쇠미역의 일반성분은 건량 기준으로 당질 45.4%, 조단백질 15.0%, 조지방 2.3% 및 조회분 33.1%이었고, 구멍쇠미역 100 g의 함유 열량은 262.3 kcal로 분석되었으며, 총 식이섬유소 함량은 34.0%로 나타났다. 또한, 총 18종의 아미노산으로 구성되었으며, 그 함량은 12,402.42 mg이었고, 무기질 중 칼륨의 함유량이 가장 높았고, 그 다음이 칼슘, 나트륨, 마그네슘 순으로 나타나, 알칼리성 재료임을 알 수 있었다. 구멍쇠미역 추출물의 총 페놀 함량 및 총 플라보노이드 함량분석 결과, 각각 $34.1{\pm}2.56mg/g$과 $4.9{\pm}0.26mg/g$으로 나타났다. 다양한 항산화 평가 모델(DPPH, FRAP, 환원력, ABTS)을 통하여 구멍쇠미역 추출물의 항산화 활성을 측정한 결과, 구멍쇠미역 추출물의 농도가 증가함에 따라 항산화능이 유의적으로 증가하는 것으로 나타났다. 이상의 결과로부터 구멍쇠미역은 식품으로서의 이용가치가 매우 크며, 구멍쇠미역 추출물은 항산화능이 있음을 확인할 수 있었다.

• 한국환경보건학회지
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• 제41권3호
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• pp.182-190
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• 2015

Objectives: To introduce a protocol of Mobi-kids study which was aimed to examine an association between radiofrequency (RF) radiation exposure by mobile phone use and brain tumor risk in children and adolescents. Methods: The Mobi-kids study was a multinational matched case control study using a standardized protocol with the number of subjects targeted about 1,000 cases and 2,000 controls aged 10 to 24. In Mobi-Kids Korea, the source population was restricted to Seoul, Incheon, and Gyeonggi-do province. Eligible cases of primary brain tumor (glioma, meningioma, and others) were diagnosed from January 2012 to June 2015. Eligible controls were appendicitis patients operated during the study period. Two controls were matched on age, gender, and study region for 1 case. Information about pattern and history of mobile phone use and other covariates were obtained by face to face interview by trained interviewer. The Mobi-kids study has been involved in Mobi-expo as a validation study about mobile phone use, XGridmaster to localize tumor in the brain for RF energy calculation, and histological review for validation of diagnosis. Results: The Mobi-kids was the first and largest study in children and adolescents to estimate risk of brain tumor in association with the RF energy absorption in the brain estimated by mobile phone use. Forty-six-cases and 54 controls were collected as of September 2014 in Korea. Conclusions: The meaningful results of the study were expected because of the largest sample size, high validity of EMF exposure assessment as well as the susceptible study populationof children and adolescents.

• 한국산학기술학회논문지
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• 제18권6호
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• pp.209-218
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• 2017

본 연구는 대학생의 사회적 지지(가족의 사회적 지지, 친구의 사회적 지지), 심리적 행동특성(자기존중감, 대인의존행동특성, 통제신념) 및 스트레스가 우울수준에 미치는 영향을 알아보기 위해 실시하였다. 조사대상은 D광역시의 남녀 대학생 546명으로 하였으며, 연구방법은 2015년 10월에 자기기입식 설문조사에 의하였다. 연구결과, 조사대상자의 우울수준은 가족의 사회적 지지, 친구의 사회적 지지, 자기존중감 및 통제신념이 높은 군보다 낮은 군에서 유의하게 높은 반면, 대인의존행동 특성과 스트레스가 낮은 군보다 높은 군에서 유의하게 높았다. 또한, 조사대상자의 우울수준은 가족의 사회적 지지, 친구의 사회적 지지, 자기존중감 및 통제신념과는 유의한 음의 상관관계를 보인 반면, 대인의존행동특성 및 스트레스와는 유의한 양의 상관관계를 보였다. 공분산 구조분석 결과, 스트레스원의 인지는 사회적 지지의 인지나 심리적 행동특성보다 우울수준에 더 큰 영향을 미쳤으며, 스트레스원의 인지가 높을수록, 사회적 지지의 인지나 심리적 행동특성이 낮을수록 우울수준을 증가시키는 효과가 있는 것으로 나타났다. 위와 같은 결과는 대학생들의 우울수준은 사회적 지지와 심리적 행동특성이 낮고, 스트레스가 높을 경우 증가한다는 것을 시사하고 있으며, 특히 다른 요인들보다 스트레스에 의해 더 큰 영향을 받고 있음을 알 수 있다. 따라서 대학생들의 우울수준을 감소시키기 위해서는 학생들이 경험하는 주요 스트레스원이 무엇인지 파악하고 스트레스원을 감소시키기 위한 노력이 필요하다고 생각된다.

• 한국해양환경ㆍ에너지학회지
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• 제18권3호
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• pp.189-206
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• 2015

우리나라 주변해역의 해양환경에 밀접한 영향이 있는 동중국해 북부해역의 해양환경 특성을 이해하기 위하여 해양환경 인자의 장기변동 양상을 파악하여 동중국해 북부해역의 해양특성을 구명하기 위하여 연구를 수행하였다. 조사 방법은 1995년부터 2014년까지 20년간 계절에 따라 국립수산과학원 한국해양자료센터(KODC : Korea Oceanographic Data Center)의 동중국해 북부해역의 해양조사 자료(수온, 염분, 용존산소, 영양염, 엽록소-a)를 이용하였다. 연구기간 동안 동중국해 북부해역에 영향을 미치는 주요 수괴는 장강희석수, 대만난류수, 황해저층냉수, 쿠로시오 기원수로 구분되었다. 표층과 아표층에 형성되는 장강희석수와 대만난류수는 20년간 세력이 약화되었으며, 중층에 형성되는 쿠로시오 기원수의 세기는 현저히 감소하는 추세를 나타내었다. 그러나 황해저층냉수는 세력이 확장되는 추세를 나타내었다. 인산염과 규산염은 감소하는 추세였으며 인산염은 2009년 이후 표층에서 고갈되는 양상을 나타내었다. 이러한 원인으로는 장강희석수와 대만난류수를 통해 유입되는 영양염의 농도가 낮기 때문인 것으로 판단된다. 엽록소-a의 농도는 연구기간 동안 증가하는 경향을 나타냈으며 이러한 원인은 수온증가와 황해저층냉수로부터 영양염 공급, 샨샤댐 건설에 의한 부유물질 감소에 따른 광투과 증가의 영향으로 판단된다.

• Journal of Nutrition and Health
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• 제57권2호
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• pp.211-227
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• 2024

본 연구에서는 해조류 섭취와 염증과 관련된 유전자의 변이 및 다유전자 위험 점수 간의 상호작용이 염증에 미치는 영향을 확인하였다. 남성과 여성 모두 PRS가 높은 그룹에서 염증 발생 위험은 증가하였다. 본 연구에서는 해조류의 섭취가 염증과 직접적인 관련이 있는 것으로 밝혀지지 않았지만, 해조류 섭취와 다유전자 위험 점수 변이 사이에선 통계적으로 유의한 결과를 보였다. 특히, 낮은 해조류의 섭취는 높은 다유전자 위험 점수를 가진 여성에서 고염증 발생 위험이 높았다. 따라서 본 연구결과는 한국인에게서 작용하는 염증 및 염증질환에 대한 유전자 소인을 파악할 수 있고 면역 체계의 균형 및 건강 유지에 새로운 중재방안을 제시할 수 있음을 기대한다.

• 지역사회간호학회지
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• 제11권1호
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• pp.209-221
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• 2000

I began the study to identify the issues related to knowledge. attitude and behavior regarding smoking by sixth graders. which will ultimately lead to the development of a smoking prevention program that will not only help deter school-age children from smoking, but also make them aware of the more desirable behaviors and techniques for healthier life. The results are as follows: 1. Smoking Behavior: Of the focus group. 4.15% are current smokers and 18.23% are ever smokers. 2. Correlation between smoking knowledge and ever smoking: Ever smoking sample($11.10{\pm}3.66$) is less knowledge able than the never-smoking sample($12.17{\pm}3.95$), (t=3.23. p=.001). 3. Correlation between smoking attitude and ever smoking: Ever smoking sample($28.12{\pm}8.51$) was less desirable than the never-smoking sample($l2.17{\pm}3.95$). (t=8.24, p=.000). 4. Correlation between smoking Knowledge and smoking attitude: knowledge about smoking and attitude toward smoking are quantitatively correlated in such way that the more knowledgeable the child is about smoking. the more desirable the attitude toward smoking is(r=.17. p=.000). 5. Correlation between socio-anthropological characteristics and ever smoking: family . atmosphere($x^2$=16.49. p=.001), school life ($x^2$=l1.58, p= .003), grades in school( $x^2$=11.89. p=.003), gender($x^2$=8.97. p=.003). friends' gathering place($x^2$=13.19. p=.02), marital status of parents(p* =.03). and family's financial status($x^2$=6.71. p=.035). In addition, Correlation between somking-environmental characteristics and ever smoking: number of friends who smoke($x^2$=76.01. p=.001). information source for smoking($x^2$=48.03. p=.001), whether or not siblings smoke($x^2$=26.07, p=.001), whether or not female relatives smoke ( $x^2$= 15.65. p= .001), whether or not father smokes ($x^2$= 12.10. p= .007), errands to buy cigarettes for someone($x^2$=9.18. p=.010), and whether or not male relatives smoke ($x^2$=8.82. p=.35) 6. Results of the logistic analysis performed to identify the factors correlated to ever smoking show that: one point decrease in attitude score translates to 25.39 times' increase in ever smoking one person decrease in the number of friends who smoke translates to 0.66 times' decrease in ever smoking: the group where the father has quit smoking has 1.40 times more ever smoking than the group where the father does not smoke at all: and likewise, the group where the father currently smokes has 1.40 times more ever smoking than the group where the father has quit smoking. 7. The overall cause-and-effect relationship between the ever smoking and the related factors: attitude toward smoking caused ever smoking by -.43, smoking by friends, by .12, marital status of arents, by .05, school life. by .04, gender, by -.03, and smoking by father, by -.02. Knowledge about smoking (t=-1.67) did not cause significant effects on ever smoking.

• 가정과삶의질연구
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• 제27권6호
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• pp.65-82
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• 2009

The following research aimed to determine the effect of stress among middle school students on their addiction to the Internet. This research's target was a group of male students who had a high probability of getting addicted to the Internet while playing c/t games. The study distributed 357 questionnaires and used 340 copies, which meant discarding 17 copies that were considered inadequate. The research results are as follows: First, there appeared subordinate factors in the stress suffered by the students. These included stress from their families, from conflicts with their teachers, from the living environment, current schoolwork and future course in college, insecurity over their physical appearance, bullying from other students, and relationships with friends. Among these factors, stress caused by conflicts with teachers and family was the most frequently cited, while stress from their friends was the least cited. The motive in using the Internet was found to be bound with several factors. These include: a form of diversion, a way to communicate with others, a means in coping with loneliness, a source of news and information, a form of passing away time, a kind of habit, and others. Among these motives, passing away time and indulging a habit were cited the most, followed by news and information search, and a form of diversion. Second, as a subordinate factor in Internet addiction, the following were cited: formation of tolerance, health issues, occurrence of problems related to daily life, satisfaction or a pleasant sensation, withdrawal, cover-up on the use of the Internet, and formation of virtual interpersonal relationships, and others. Among these, the formation of tolerance came out the highest, followed by health issues, daily life, and problems related to daily life. Third, in terms of the effects of stress on the motive in using the Internet, the research found that the more the students felt stressed out by conflicts with their teachers and family, the more they tended to use the Internet to communicate with others, to cope with loneliness, to obtain newsI and information, to passawaytime, and to indulge a habit Also, the more they felt stressed out by the living environment, the more they tended to use the Internet to communicate with others, to cope with loneliness, and use news and information. The more they felt stressed out by their schoolwork and future course in college, they tended to use the Internet as a form of diversion and to secure news and information. The more they felt stressed out by their insecurity over their physical appearance and being victimized by bullies, the more they tended to use the Internet to cope with loneliness. Fourth, as for the effect of several variables on student addiction to the Internet, the study found that the more students felt stressed out by their living environment, by schoolwork and future course in college, by their physical appearance, and bullying from other students, the more they used the Internet as a form of diversion, a communication tool, and as a means of passing away time or indulging a habit. The study came up with the finding that the more the students used the computer and the Internet, the probability of their getting addicted to the Internet got higher.