Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Comparison of hematological values of conventional pigs and transgenic pigs supressed in immune rejection response

일반돼지와 면역 거부반응이 억제된 형질전환돼지의 혈액 성상 비교

  • Cho, Ara (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Oh, Keon Bong (Animal Biotechonology Division, National Institute of Animal Science, RDA) ;
  • Roh, Jae-Hee (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Jung, Young-Hun (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Jung, Suk-Han (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Kang, Myoung-Geum (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Kim, Mi-Suk (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Do, Yoon Jung (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Oh, Sang-Ik (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Kim, Eunju (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Yoo, Jae Gyu (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA) ;
  • Choe, Changyong (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
  • 조아라 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 오건봉 (농촌진흥청 국립축산과학원 동물바이오공학과) ;
  • 노재희 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 정영훈 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 정숙한 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 강명금 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 김미숙 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 도윤정 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 오상익 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 김은주 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 류재규 (농촌진흥청 국립축산과학원 가축질병방역과) ;
  • 최창용 (농촌진흥청 국립축산과학원 가축질병방역과)
  • Received : 2019.09.10
  • Accepted : 2019.12.19
  • Published : 2019.12.30
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Abstract

Blood test is a useful tool in establishing medical treatment for livestock. It provides information such as disease diagnosis, treatment effects, prognostic judgment, and health status. This study compared the value of erythrocytes and leukocytes among conventional, transgenic miniature, and transgenic conventional pigs aged six months to 24 months. Further, it analyzed the aspects of hematological value changes according to the pigs' ages. As a result, the number of red blood cells (RBC), which include hemoglobin, and hematocrit, and the number of white blood cells (WBC), which include neutrophils, and lymphocyte, were high among transgenic miniature pigs, compared with the conventional and transgenic conventional pigs. Conventional pigs showed similar values of RBC and WBC regardless of transgenesis. In comparing their age, the RBC decreased as the age increased compared with the pigs among all the three groups aged of 6~12 months. On the other hand, WBC and neutrophils showed no significant difference regardless of different ages among all the three groups. However, various counts in RBC and WBC were mostly found to be higher in each age in transgenic miniature pigs than in conventional and transgenic conventional pigs. The results of this study show that the values of RBC and WBC were generally higher in transgenic miniature pigs than in conventional and transgenic conventional pigs. Based on this research, hematological values can be widely used in diagnosing diseases or checking the health status of transgenic pigs that are used as disease models, organ transplant source and alike.

Keywords

References

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