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모비키즈: 통신전자파 노출과 어린이청소년의 뇌종양에 관한 환자 -대조군 연구 프로토콜

Mobi-kids: A Case-control Study Protocol on Electromagnetic Field Radiation Exposure from Telecommunication and Brain Tumors in Children and Adolescents

  • 최경화 (한림대학교 의과대학 임상역학연구소) ;
  • 김동석 (연세대학교 세브란스병원 소아신경외과) ;
  • 이정일 (성균관대학교 의과대학 삼성서울병원 신경외과) ;
  • 나영신 (울산대학교 서울아산병원 신경외과) ;
  • 피지훈 (서울대학교어린이병원 소아청소년신경외과) ;
  • 안영환 (아주대학교 아주대학교병원 신경외과) ;
  • 권종화 (한국전자통신연구원 전파환경연구실) ;
  • 이애경 (한국전자통신연구원 전파환경연구실) ;
  • 최형도 (한국전자통신연구원 전파환경연구실) ;
  • 하미나 (단국대학교 의과대학 예방의학교실)
  • Choi, Kyung-Hwa (Hallym Research Institute of Clinical Epidemiology, Hallym University) ;
  • Kim, Dong-Seok (Department of Pediatric Neurosurgery, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Lee, Jung-il (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Ra, Young-Shin (Department of Neurosurgery, Asan Medical Center) ;
  • Phi, Ji Hoon (Division of Pediatric Neurosurgery, Seoul National University Children's Hospital) ;
  • Ahn, Young Hwan (Department of Neurosurgery, Ajou University Hospital) ;
  • Kwon, Jong Hwa (EM Environment Research Team, ETRI) ;
  • Lee, Ae-Kyoung (EM Environment Research Team, ETRI) ;
  • Choi, Hyung-Do (EM Environment Research Team, ETRI) ;
  • Ha, Mina (Department of Preventive Medicine, Dankook Univeristy College of Medicine)
  • 투고 : 2015.04.21
  • 심사 : 2015.06.28
  • 발행 : 2015.06.28

초록

Objectives: To introduce a protocol of Mobi-kids study which was aimed to examine an association between radiofrequency (RF) radiation exposure by mobile phone use and brain tumor risk in children and adolescents. Methods: The Mobi-kids study was a multinational matched case control study using a standardized protocol with the number of subjects targeted about 1,000 cases and 2,000 controls aged 10 to 24. In Mobi-Kids Korea, the source population was restricted to Seoul, Incheon, and Gyeonggi-do province. Eligible cases of primary brain tumor (glioma, meningioma, and others) were diagnosed from January 2012 to June 2015. Eligible controls were appendicitis patients operated during the study period. Two controls were matched on age, gender, and study region for 1 case. Information about pattern and history of mobile phone use and other covariates were obtained by face to face interview by trained interviewer. The Mobi-kids study has been involved in Mobi-expo as a validation study about mobile phone use, XGridmaster to localize tumor in the brain for RF energy calculation, and histological review for validation of diagnosis. Results: The Mobi-kids was the first and largest study in children and adolescents to estimate risk of brain tumor in association with the RF energy absorption in the brain estimated by mobile phone use. Forty-six-cases and 54 controls were collected as of September 2014 in Korea. Conclusions: The meaningful results of the study were expected because of the largest sample size, high validity of EMF exposure assessment as well as the susceptible study populationof children and adolescents.

키워드

참고문헌

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