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http://dx.doi.org/10.7853/kjvs.2019.42.4.193

Comparison of hematological values of conventional pigs and transgenic pigs supressed in immune rejection response  

Cho, Ara (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Oh, Keon Bong (Animal Biotechonology Division, National Institute of Animal Science, RDA)
Roh, Jae-Hee (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Jung, Young-Hun (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Jung, Suk-Han (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Kang, Myoung-Geum (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Kim, Mi-Suk (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Do, Yoon Jung (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Oh, Sang-Ik (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Kim, Eunju (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Yoo, Jae Gyu (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Choe, Changyong (Division of Animal Diseases & Healths, National Institute of Animal Science, RDA)
Publication Information
Korean Journal of Veterinary Service / v.42, no.4, 2019 , pp. 193-200 More about this Journal
Abstract
Blood test is a useful tool in establishing medical treatment for livestock. It provides information such as disease diagnosis, treatment effects, prognostic judgment, and health status. This study compared the value of erythrocytes and leukocytes among conventional, transgenic miniature, and transgenic conventional pigs aged six months to 24 months. Further, it analyzed the aspects of hematological value changes according to the pigs' ages. As a result, the number of red blood cells (RBC), which include hemoglobin, and hematocrit, and the number of white blood cells (WBC), which include neutrophils, and lymphocyte, were high among transgenic miniature pigs, compared with the conventional and transgenic conventional pigs. Conventional pigs showed similar values of RBC and WBC regardless of transgenesis. In comparing their age, the RBC decreased as the age increased compared with the pigs among all the three groups aged of 6~12 months. On the other hand, WBC and neutrophils showed no significant difference regardless of different ages among all the three groups. However, various counts in RBC and WBC were mostly found to be higher in each age in transgenic miniature pigs than in conventional and transgenic conventional pigs. The results of this study show that the values of RBC and WBC were generally higher in transgenic miniature pigs than in conventional and transgenic conventional pigs. Based on this research, hematological values can be widely used in diagnosing diseases or checking the health status of transgenic pigs that are used as disease models, organ transplant source and alike.
Keywords
Pigs; Hematology; Transgenic; Reference values;
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Times Cited By KSCI : 3  (Citation Analysis)
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