• Journal of Food Hygiene and Safety
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• v.33 no.5
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• pp.361-368
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• 2018

N-nitrosamines are probable or possible human carcinogens, which are produced by the reaction between secondary amines and nitrogen oxide in the acidic environment or by heating. Common risk assessment procedure involves the comparison between exposures expressed in the unit, mg/kg body weight/day and the Health-Based Reference dose expressed in the same unit. This procedure is suitable for the policy decision-making and is considered as inappropriate for the consumers to get information about their dietary decision-making. Therefore, the distributions of NDMA (N-nitrosodimethylamine), NDBA (N-nitrosodibutylamine), the six N-nitrosamines (NDMA, NDBA, NDEA (N-nitrosodiethylamine), NPYR (N-nitrosopyrrolidine), NPIP (N-nitrosopiperidine), and NMOR (N-nitrosomorpholine) in the menus grouped based on the presence of main ingredients and cooking methods were analyzed to generate consumer-friendly information regarding food contaminants. Recipes and intakes were taken from 2014 to 2016 KNHANES (The Korean National Health and Nutrition Examination Survey) and only the data from ages of 7 years or older were used. The contamination data were collected from the 2014~2016 Total Diet Study and all the analysis were performed using R software. Rockfish, eel, anchovy broth and pollock were mainly exposed to N-nitrosamines. In terms of cooking methods, soups and stews appeared to contain the highest amount of N-nitrosamines. Cereals, fruits, and dairy products in the ingredient categories, and rice dishes and rice combined with others in recipe categories had the lowest level exposure to N-nitrosamines. In case of N-nitrosamines, unlike other cooking related food contaminants, boiled dishes such as soups and stews and dishes mainly consisting of fishes and shellfishes had highest level of exposure, showing a large discrepancy with the previous thought of processed meat is the main source of N-nitrosamines.

• Korean Journal of Veterinary Service
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• v.42 no.4
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• pp.193-200
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• 2019

Blood test is a useful tool in establishing medical treatment for livestock. It provides information such as disease diagnosis, treatment effects, prognostic judgment, and health status. This study compared the value of erythrocytes and leukocytes among conventional, transgenic miniature, and transgenic conventional pigs aged six months to 24 months. Further, it analyzed the aspects of hematological value changes according to the pigs' ages. As a result, the number of red blood cells (RBC), which include hemoglobin, and hematocrit, and the number of white blood cells (WBC), which include neutrophils, and lymphocyte, were high among transgenic miniature pigs, compared with the conventional and transgenic conventional pigs. Conventional pigs showed similar values of RBC and WBC regardless of transgenesis. In comparing their age, the RBC decreased as the age increased compared with the pigs among all the three groups aged of 6~12 months. On the other hand, WBC and neutrophils showed no significant difference regardless of different ages among all the three groups. However, various counts in RBC and WBC were mostly found to be higher in each age in transgenic miniature pigs than in conventional and transgenic conventional pigs. The results of this study show that the values of RBC and WBC were generally higher in transgenic miniature pigs than in conventional and transgenic conventional pigs. Based on this research, hematological values can be widely used in diagnosing diseases or checking the health status of transgenic pigs that are used as disease models, organ transplant source and alike.

• Research in Community and Public Health Nursing
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• v.9 no.2
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• pp.482-501
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• 1998

As an initial step toward the improvement of sexual education in middle school students, a survey on sexual attitudes and experience was done in Kangwon - Do, Korea. Questionnaires consisted of 68 items distributed to 240 boys and 240 girls from November 1 to December 20, 1996. Answers from 420 students were subjected to an analysis with SPSS. 92.4% of the girls experienced menstruation. Of them, 74.0% showed a negative reaction. 52.0% of the boys experienced night ejaculation. Of them, 81. 7% showed a negative reaction. Boys (64.3%) masturbated more than girls (17. 6%) (p= 0.0000). The understanding of masturbation was higher in boys than in girls (p = 0.0000). 87.2% of the subjects wished meetings with the opposite sex. During the meeting with the opposite sex, 12.9% of the students enjoyed drinking or smoking, 8.8% had intercourse. Boys(91.9%) watched pornography or porno-video more than girls(40.5%)(p=0.0000). 83.3% of the girls thought that both males and females should keep their virginity untill marriage. However, only 48.6% of boys thought that(p=0.0000). Of boys who had experienced sexual touch, 34.8% had intercourse. Of the 30 students(26 boys, 4 girls) who experienced sexual intercourse, 22 students had partners of the opposite sex and were friends. First intercourse 63.4% of these students had their in middle school period. The frequencys of sexual intercourse (more than 6times) was written by 12 students (40.0%). 24 students(16 boys and 8 girls) experienced sexual violence. As for dealing with sexual violence, 14 suffered by him or herself whill 7 students discussed it with a friend. There was a significant difference in the sources of information between boys and girls(p= 0.000), 36.0% had learned from an official sexual education source, usually from school nurses (74.0%). 92.6% of the students thought that sexual education was necessary. They believed that the appropriate person for sexual education was from a school nurse (53.1%) or from parents (19.5%). According to the above results, the following might be suggested: Realistic and future-directed sexual education material should be developed : Education programs to improve students insight and control sexual desire should be prepared: a systematic approach to activate the role of school nurse in sexual education should be prepared.

• The Korean Journal of Food And Nutrition
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• v.25 no.4
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• pp.842-849
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• 2012

The purpose of this study is to determine the possibility of using Agarum cribrosum as a natural health food source. To accomplish this purpose, the contents of the general and antioxidant activities of Agarum cribrosum were measured. The contents of carbohydrate, crude protein, crude lipid and ash were 45.4%, 15.0%, 2.3% and 33.1%. The calories of Agarum cribrosum were 262.3 kcal and total dietary fiber of Agarum cribrosum was 34.0%. The protein contained a total of 18 different kinds of amino acids. The content of amino acids was 12,402.42 mg/100 g. The K was the largest mineral followed by Ca, Na and Mg, implying that Agarum cribrosum is an alkali material. The antioxidant activity of Agarum cribrosum was assessed by various radical scavenging assays using DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (ferric ion reducing antioxidant power), reducing power, and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)). All antioxidant activity of Agarum cribrosum extract increased the concentration of the dependents. Total phenolic contents of Agarum cribrosum extract were $34.1{\pm}2.56mg/g$, and total flavonoids contents were estimated at $4.9{\pm}0.26mg/g$. General nutrients and other antioxidant bioactive materials in Agarum cribrosum were also potential materials for good health food. It is expected that a follow-up study of Agarum cribrosum through developing processed food and evaluation of their functional properties would provide useful information or sources of functional foods.

• Journal of Environmental Health Sciences
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• v.41 no.3
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• pp.182-190
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• 2015

Objectives: To introduce a protocol of Mobi-kids study which was aimed to examine an association between radiofrequency (RF) radiation exposure by mobile phone use and brain tumor risk in children and adolescents. Methods: The Mobi-kids study was a multinational matched case control study using a standardized protocol with the number of subjects targeted about 1,000 cases and 2,000 controls aged 10 to 24. In Mobi-Kids Korea, the source population was restricted to Seoul, Incheon, and Gyeonggi-do province. Eligible cases of primary brain tumor (glioma, meningioma, and others) were diagnosed from January 2012 to June 2015. Eligible controls were appendicitis patients operated during the study period. Two controls were matched on age, gender, and study region for 1 case. Information about pattern and history of mobile phone use and other covariates were obtained by face to face interview by trained interviewer. The Mobi-kids study has been involved in Mobi-expo as a validation study about mobile phone use, XGridmaster to localize tumor in the brain for RF energy calculation, and histological review for validation of diagnosis. Results: The Mobi-kids was the first and largest study in children and adolescents to estimate risk of brain tumor in association with the RF energy absorption in the brain estimated by mobile phone use. Forty-six-cases and 54 controls were collected as of September 2014 in Korea. Conclusions: The meaningful results of the study were expected because of the largest sample size, high validity of EMF exposure assessment as well as the susceptible study populationof children and adolescents.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.209-218
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• 2017

This study examined the influence of social support (social support from family, social support from friends), psychological behavioral characteristics (self-esteem, interpersonal dependency, locus of control), and stress on the depression levels of college students. The study subjects were 546 college students in D city. The survey was conducted using a self-administered questionnaire in October 2015. As a result, the depression levels were significantly higher in the group showing lower family and friends' social support, self-esteem, and locus of control, while it was significantly higher in the group showing higher interpersonal dependency and stress. The depression levels of the subjects showed a negative correlation with family and friends' social support, self-esteem, and locus of control, but a positive correlation with interpersonal dependency and stress. Covariance structure analysis revealed an increase in the depression levels of college students when the awareness of the stress source was higher, and when the awareness of social support or psychological behavioral characteristics was lower. These results suggest that the depression levels of college students would be increased when the social support and psychological behavioral characteristics are low, and when stress is high. In particular, it was influenced much more by stress than other factors. Therefore, to decrease the depression levels of college students, it would be necessary to put efforts to understand their main stress sources and then reduce them.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.3
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• pp.189-206
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• 2015

The present study was conducted to investigate the oceanic characteristics of the northern East China Sea through identification of long-term variation patterns of oceanic environment factors, for the objective of gaining understanding of oceanic environment characteristics of the northern waters of East China Sea, which closely influence the oceanic environments of waters nearby South Korea. The study methodology included the use of oceanographic data (water temperature, salinity, dissolved oxygen, nutrients, and chlorophyll-a) on the northern East China Sea from the Korea Oceanographic Data Center (KODC), collected by season for 20 years between 1995 and 2014. Moreover, for the study on the distribution of nutrients, chlorophyll-a. The main water masses that affected the northern East China Sea during the study period were classified as Changjiang diluted water (CDW), Tiawan current warm water (TCWW), Yellow Sea cold water (YSCW), and Kuroshio source water (KW). The forces of CDW and TCWW that forms on the surface and sub-surface layers had weakened for 20 years and the force of KW that forms on the intermediate layer showed a distinctively decreasing trend. However, YSCW showed a trend of expanding its force. Phosphate and silicate exhibited a decreasing tendency and phosphate showed a pattern of being depleted on the surface layer after 2009. It is determined that one of the reasons for this is the concentration of nutrients introduced through CDW and TCWW being too low. The concentration of chlorophyll-a exhibited an increasing tendency during the study period, the reasons for which are determined to be the influences of increase in water temperature, supply of nutrients via YSCW, and increases in light transmission from decrease in suspended solid due to the construction of the Three Gorges Dam.

• Journal of Nutrition and Health
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• v.57 no.2
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• pp.211-227
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• 2024

Introduction: Seaweed is a sustainable and underexplored source of bioactive compounds with potent anti-inflammatory activities. However, studies on the interaction between seaweed and genes on inflammation are limited. Purpose: We aimed to evaluate the relationships between seaweed consumption and the polygenic risk scores (PRS) and their interactions with high-sensitivity C-reactive protein (hs-CRP) levels. Methods: Information on seaweed consumption was collected using a food frequency questionnaire, which included laver, kelp, and sea mustard among the items consumed. A total of 31 hs-CRP-related single nucleotide polymorphisms (SNPs) were selected using genome-wide association studies and clumping analysis, and the individual PRS were calculated by weighting the effect size of each allele in the selected SNPs of 39,369 middle-aged (≥40 years) Koreans using the Korean Genome and Epidemiology Study (KoGES)-Health Examinees (HEXA) cohort data. To investigate the interaction between seaweed intake and the PRS on hs-CRP levels >1 mg/L, hazard ratios (HRs) and 95% confidence intervals (CIs) were assessed using multivariable Cox proportional hazards models. Results: During a mean follow-up period of 4.8 years, we recorded 436 patients with elevated hs-CRP levels. Women in the highest tertile of the PRS with the lowest quartile of seaweed intake had an increased incidence of elevated hs-CRP levels compared with women in the lowest tertile of the PRS with the lowest seaweed intake quartile (HR 2.34, 95% CI 1.23-4.45). No significant association was observed among the men. Conclusion: In conclusion, we identified a new interaction between the PRS, seaweed intake, and inflammation in Korean women, and this study suggests that the interaction between the identification of genetic predisposition and dietary seaweed intake may have an impact on determining the risk of developing hyperinflammation in the future.

• Research in Community and Public Health Nursing
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• v.11 no.1
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• pp.209-221
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• 2000

I began the study to identify the issues related to knowledge. attitude and behavior regarding smoking by sixth graders. which will ultimately lead to the development of a smoking prevention program that will not only help deter school-age children from smoking, but also make them aware of the more desirable behaviors and techniques for healthier life. The results are as follows: 1. Smoking Behavior: Of the focus group. 4.15% are current smokers and 18.23% are ever smokers. 2. Correlation between smoking knowledge and ever smoking: Ever smoking sample($11.10{\pm}3.66$) is less knowledge able than the never-smoking sample($12.17{\pm}3.95$), (t=3.23. p=.001). 3. Correlation between smoking attitude and ever smoking: Ever smoking sample($28.12{\pm}8.51$) was less desirable than the never-smoking sample($l2.17{\pm}3.95$). (t=8.24, p=.000). 4. Correlation between smoking Knowledge and smoking attitude: knowledge about smoking and attitude toward smoking are quantitatively correlated in such way that the more knowledgeable the child is about smoking. the more desirable the attitude toward smoking is(r=.17. p=.000). 5. Correlation between socio-anthropological characteristics and ever smoking: family . atmosphere($x^2$=16.49. p=.001), school life ($x^2$=l1.58, p= .003), grades in school( $x^2$=11.89. p=.003), gender($x^2$=8.97. p=.003). friends' gathering place($x^2$=13.19. p=.02), marital status of parents(p* =.03). and family's financial status($x^2$=6.71. p=.035). In addition, Correlation between somking-environmental characteristics and ever smoking: number of friends who smoke($x^2$=76.01. p=.001). information source for smoking($x^2$=48.03. p=.001), whether or not siblings smoke($x^2$=26.07, p=.001), whether or not female relatives smoke ( $x^2$= 15.65. p= .001), whether or not father smokes ($x^2$= 12.10. p= .007), errands to buy cigarettes for someone($x^2$=9.18. p=.010), and whether or not male relatives smoke ($x^2$=8.82. p=.35) 6. Results of the logistic analysis performed to identify the factors correlated to ever smoking show that: one point decrease in attitude score translates to 25.39 times' increase in ever smoking one person decrease in the number of friends who smoke translates to 0.66 times' decrease in ever smoking: the group where the father has quit smoking has 1.40 times more ever smoking than the group where the father does not smoke at all: and likewise, the group where the father currently smokes has 1.40 times more ever smoking than the group where the father has quit smoking. 7. The overall cause-and-effect relationship between the ever smoking and the related factors: attitude toward smoking caused ever smoking by -.43, smoking by friends, by .12, marital status of arents, by .05, school life. by .04, gender, by -.03, and smoking by father, by -.02. Knowledge about smoking (t=-1.67) did not cause significant effects on ever smoking.

• Journal of Families and Better Life
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• v.27 no.6
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• pp.65-82
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• 2009

The following research aimed to determine the effect of stress among middle school students on their addiction to the Internet. This research's target was a group of male students who had a high probability of getting addicted to the Internet while playing c/t games. The study distributed 357 questionnaires and used 340 copies, which meant discarding 17 copies that were considered inadequate. The research results are as follows: First, there appeared subordinate factors in the stress suffered by the students. These included stress from their families, from conflicts with their teachers, from the living environment, current schoolwork and future course in college, insecurity over their physical appearance, bullying from other students, and relationships with friends. Among these factors, stress caused by conflicts with teachers and family was the most frequently cited, while stress from their friends was the least cited. The motive in using the Internet was found to be bound with several factors. These include: a form of diversion, a way to communicate with others, a means in coping with loneliness, a source of news and information, a form of passing away time, a kind of habit, and others. Among these motives, passing away time and indulging a habit were cited the most, followed by news and information search, and a form of diversion. Second, as a subordinate factor in Internet addiction, the following were cited: formation of tolerance, health issues, occurrence of problems related to daily life, satisfaction or a pleasant sensation, withdrawal, cover-up on the use of the Internet, and formation of virtual interpersonal relationships, and others. Among these, the formation of tolerance came out the highest, followed by health issues, daily life, and problems related to daily life. Third, in terms of the effects of stress on the motive in using the Internet, the research found that the more the students felt stressed out by conflicts with their teachers and family, the more they tended to use the Internet to communicate with others, to cope with loneliness, to obtain newsI and information, to passawaytime, and to indulge a habit Also, the more they felt stressed out by the living environment, the more they tended to use the Internet to communicate with others, to cope with loneliness, and use news and information. The more they felt stressed out by their schoolwork and future course in college, they tended to use the Internet as a form of diversion and to secure news and information. The more they felt stressed out by their insecurity over their physical appearance and being victimized by bullies, the more they tended to use the Internet to cope with loneliness. Fourth, as for the effect of several variables on student addiction to the Internet, the study found that the more students felt stressed out by their living environment, by schoolwork and future course in college, by their physical appearance, and bullying from other students, the more they used the Internet as a form of diversion, a communication tool, and as a means of passing away time or indulging a habit. The study came up with the finding that the more the students used the computer and the Internet, the probability of their getting addicted to the Internet got higher.