• 대한두경부종양학회지
• /
• 제32권1호
• /
• pp.49-52
• /
• 2016

The lobular capillary hemangioma (LCH) was previously known to pyogenic granuloma and is benign vascular lesion which grows rapidly on skin and mucosa. It arises from whole body, but oral and nasal cavities are most predilection sites in the head and neck area. The laryngeal LCH looks like a granulomatous lesion of posterior glottis and its common etiology are tracheal intubation and laryngopharyngeal reflux disease etc. The LCH in larynx can cause blood tinged sputum and lump sense. The lesions refractory to medical therapy or causing dyspnea may require surgical excision. A 74-year-old man who presented gradually aggravated dyspnea, lump sensation and hoarseness of one month came to our hospital. The stroboscopic examination revealed large well-margined glottic mass. It was excised with $CO_2$ laser and finally diagnosed as LCH. We present a rare unique case of glottic LCH with a review of literatures.

• Journal of Chest Surgery
• /
• 제45권3호
• /
• pp.196-198
• /
• 2012

Granular cell tumors are uncommon soft tissue neoplasm of nerve sheath origin, which are predominately benign. Granular cells can be found at any site in the body including the tongue, skin, subcutaneous tissue, breast, gastrointestinal, and urogenital systems. However, granular cell tumors have only been rarely described in the chest wall. Here we report a case of a granular cell tumor that occurred in the chest wall of a 59-year-old woman, along with a review of the literature.

• Journal of Periodontal and Implant Science
• /
• 제26권1호
• /
• pp.68-79
• /
• 1996

To investigate the efficiency of a fibrous collagen membrane(FCM) composed of bovine skin type I atelocollagen as a carrier for BMP, partially purified bovine BMP/FCM($0.3mg/10{\times}5{\times}1mm$) composites were implanted into the dorsal subcutaneous tissue of rats. FCM alone was also implanted as a control. The implants were harvested at 1, 2, 3, and 10 weeks after implantation, then prepared for routine light microscopic observation. The FCM alone did not induce osteogenesis and revealed no specific foreign body reaction nor was there any definite resorptive evidence for 10 weeks after implantation, while the BMP/FCM composites induced favorable bone formation in a process that resembled an endochondral and direct ossification mode. At 10 weeks, the well formed bone confined to embedded collagen fibers revealed hematopoietic marrow between bony trabeculae without evidence of resorptive or degenerative changes . These findings support the suggestion that BMP may induce undifferentiated mesenchymal cells into either chondroblasts or osteoblasts or both independantly according to the chemico- physical characteristics of the carrier, which develops the endochondral and/or direct bone formation process, and suggest that the FCM may be a favorable carrier for BMP.

• Journal of Yeungnam Medical Science
• /
• 제31권1호
• /
• pp.48-51
• /
• 2014

Multiple symmetric lipomatosis (MSL) is a rare disease characterized by symmetrical massive fatty deposits on the face, neck, shoulders, and upper trunk. We report a 74-year-old man who complained of painless subcutaneous nodules on his posterior neck that developed 3 weeks earlier. In a week, variably-sized similar lesions developed on both his shoulders and upper extremities. At the time of his hospital visit, several firm nodules as big as a walnut to a child's fist and with the normal-skin-hue were observed on his posterior neck, both shoulders, upper extremities, and trunk. The histological examination of his upper left arm revealed more mature adipocytes without encapsulation in the subcutaneous tissue. MSL was generally known to occur slowly over months or years. However, this is an unusual case that showed a fast-growing nature.

• 셀메드
• /
• 제10권3호
• /
• pp.24.1-24.6
• /
• 2020

Kushta Jast (KJ) is a unique herbo-mineral preparation of the Unani System of Medicine (USM) which is prepared by taklis (calcination) and prescribed by the practitioners of USM for the treatment of various ailments, including the respiratory ailments. It is used as muqawwi (tonic) to boost the immunity (Muqawwi-i-badan), and can increase the phagocyte activity of the immune cells, thereby, promoting the growth and spread of lymphocytes and increasing circulating antibodies to neutralize a harmful pathogen and reduce humma or body fever (Dafi'-i-humma). Incidentally, the principal mineral component of KJ, zinc, has been widely acknowledged for its beneficial influence on the immune function, and decrease the risk of developing serious respiratory illnesses. In this manuscript, we provide a glimpse of the literature on KJ and postulate its potential beneficial effects in respiratory infections, including COVID-19.

• Archives of Plastic Surgery
• /
• 제42권5호
• /
• pp.630-634
• /
• 2015

Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign mesenchymal lesion with incidental histologic findings. Surgical excision is recommended as the treatment of choice for PASH, although the recurrence rates after excision range from 15% to 22%. A 46-year-old-female presented with a six-month history of bilateral breast enlargement and painful sensation mimicking inflammatory carcinoma. Imaging studies demonstrated innumerable enhancing nodules in both breasts. Due to the growth of the lesions and progressive clinical symptoms, bilateral subcutaneous mastectomy was performed. Grossly, the specimens were round and well-circumscribed, and the histologic examination revealed PASH. After mastectomy, we created a pocket with the pectoralis major muscle and a lower skin flap, which was deepithelized. Anatomical mammary implants were inserted, and the nipple areolar complex was transferred to a new position as a free graft. The aesthetic result was satisfactory after twelve months of follow-up.

• 대한두경부종양학회지
• /
• 제33권1호
• /
• pp.35-38
• /
• 2017

The extranodal nasal NK/T-cell lymphoma was formerly known as lethal midline granuloma due to its most common clinical pattern like a destructive midline facial tumor. It often spread to other extranodal sites, such as skin, soft tissue, testis, upper respiratory tract, and gastrointestinal tract etc. For this reason, the term of extranodal NK/T-cell lymphoma, nasal type is preferred. Its disease entity may have a prominent admixture of inflammatory cells and necrotic tissues, further causing difficulty in diagnosis. A 44-year-old man was visited to our clinic with complaints of dysphagia and odynophagia during six months. He underwent three times punch biopsies and then, two times incisional biopsies. Finally, He was diagnosed as extranodal NK/T-cell lymphoma, nasal type involving oropharynx and supraglottis. We report an extremely rare case of extranodal NK/T-cell lymphoma, nasal type occurred in oropharynx and supraglottis with a brief review of literature.

• 대한임상검사과학회지
• /
• 제39권2호
• /
• pp.91-95
• /
• 2007

The number of children patients with tinea pedis and onychomycosis diagnosed on clinical findings and culture at the Catholic Dermatological Clinic in Daegu City were 144,446 for 2 years from January 2005 to December 2006. 120 children were suspected of having clinical onychomycosis or tinea pedis. KOH smears and cultures on the Potato corn meal dextrose agars (PDCA) were done for the suspected toe webs, nails and uninvolved neighbor toe webs. Socks were dusted and cultured to check contamination of clothes. Family infections were checked by questionnaire. The incidence was 92 (0.06%) out of 144,446 outpatients in tinea pedis, 28 (0.02%) in onychomycosis. Trichophyton(T.) rubrums were isolated from all of the 7 cases of onychomycosis. T. mentagrophytes was isolated from 5 cases of the tinea pedis patients and T. rubrum was isolated from 50 (92.5%) cases of the tinea pedis. The right side was predominant for onychomycosis of both toe nails (23 of 25) and finger nails (3 of 3). No fungal elements were detected from normal looking neighbor toe webs by KOH examinations. However, culture on PDCA agars showed T. rubrum isolates from 3 toe webs. 7 showed positive cultures from the socks. From the questionnaire, 94 had family infections.

• 대한두경부종양학회지
• /
• 제25권1호
• /
• pp.33-35
• /
• 2009

Purpose : Granular cell tumour(GCT) is a rare benign tumour that can arise in anywhere throughout the body. Histopathological diagnosis of malignancy is difficult. We report a case of a granular cell tumor which developed on lower lip. Methods : A 58-year-old male had a palpable mass and whitish plaque in the oral mucosa for three months. Results : Under local anasthesia, the tumor was removed through wide excision including normal skin margin. Immediate reconstruction using local flap was done. Pathologic observation showed nests of polygonal cells with abundant granular, eosinophilic cytoplasm and round nuclei. Immunohistopathologic staining showed positive reaction on S-100 protein Conclusion : The results support the hypothesis that granular cell tumor is derived from Schwann cells. We report here on a case of granular cell tumor of lower lip that was successfully treated with radical resection.

• 한국수산과학회지
• /
• 제23권5호
• /
• pp.353-360
• /
• 1990

The bacterium Edwardsiella tarda was injected into healthy snakeheads (Channa argus) in order to prove the causative agent of ascite. The bacterium dominantly isolated from 2 cultured ascite snakeheads was injected into fish by the dose of $5\times10^6$ CFU/ 0.25ml, but the same dose of $0.65\%$ physiological saline was injected into the each control. The injected fish was divided into 4 groups such as intraperitoneal, intramuscle, control intra-peritoneal and control intramuscle according to their injection points. Each was composed of 10 healthy snakeheads respectively. Ascites and haemorrhagic ulcers became distinct 5 days after injection, but controls did not show any abnormal symptoms during the experimental period. Edwardsiella tarda was reisalated out of the injected fish's ascite, liver, kidney, spleen and haemorrhagic ulcer on the skin. Regardless of the injecting methods, liver was necrotized more severely than any other internal organ, but both the glomeruli of kidney and spleen were considerably damaged. Necrosis of muscle and a number of leucocytes were observed at the ulcerous region of the intramuscular injected fish. It is concluded that judging from the above results the Edwardsiella tarda is a causative agent to cause ascite in snakehead.