Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Granular Cell Tumor in the Lower Lip : A Case Report

하구순의 과립세포종 증례보고

  • Hur, Gi-Yeun (Department of Plastic and Reconstructive Surgery, Hanil Hospital) ;
  • Oh, Suk-Joon (Department of Plastic and Reconstructive Surgery, Hallym University Sacred Heart Hospital) ;
  • Koh, Sung-Hoon (Department of Plastic and Reconstructive Surgery, Hallym University Sacred Heart Hospital) ;
  • Cha, Jeong-Ho (Department of Plastic and Reconstructive Surgery, Hallym University Sacred Heart Hospital) ;
  • Min, Kwang-Seon (Department of Pathology, Hallym University Sacred Heart Hospital)
  • 허지연 (한일병원 성형외과) ;
  • 오석준 (한림대학교 의과대학 성형외과학교실) ;
  • 고성훈 (한림대학교 의과대학 성형외과학교실) ;
  • 차정호 (한림대학교 의과대학 성형외과학교실) ;
  • 민광선 (한림대학교 의과대학 병리학교실)
  • Published : 2009.05.22
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Abstract

Purpose : Granular cell tumour(GCT) is a rare benign tumour that can arise in anywhere throughout the body. Histopathological diagnosis of malignancy is difficult. We report a case of a granular cell tumor which developed on lower lip. Methods : A 58-year-old male had a palpable mass and whitish plaque in the oral mucosa for three months. Results : Under local anasthesia, the tumor was removed through wide excision including normal skin margin. Immediate reconstruction using local flap was done. Pathologic observation showed nests of polygonal cells with abundant granular, eosinophilic cytoplasm and round nuclei. Immunohistopathologic staining showed positive reaction on S-100 protein Conclusion : The results support the hypothesis that granular cell tumor is derived from Schwann cells. We report here on a case of granular cell tumor of lower lip that was successfully treated with radical resection.

Keywords

References

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