• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.198-211
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• 1994

After giuing some anti-high blood pressure medicine of boiled-compressed fluid and 5-Kinds factors(Hydralazine, Verapamil, Clonidine, Furosemide and Hydrochlorothiazide with Kangsimsan to animals in single or together. I got the following conclusion in comparing blood-pressure and pulse of circulating system with urinating operation. 1. By joint-use of Kangsimsan and Hydralazine. it was found out that the effect of blood-pressure lowering continues longer in together-use than in single. And I coule see that the number of pulse increased. 2. By joint-use of Kangsimsan and Verapamil. the blood-pressure lowering operation was kept better in together-use than in single. the number of pulse was not affected any. 3. By joint-use of Kangsimsan and Clonidine the blood-pressure lowering operation was not found out any concrete result. 4. By joint-use of Kangsimsan and Furosemide. the Remarkble effect of Urinization was recognized to be much better in joint-use than in single. 5. By joint-use of Kangsimsan and Hydrochlorothiazide. the suppressing effect of urinization was recognized to be much better in joint-use than in single. Therefore in consideration of the above study and observation. when the joint-use of Kangsimsan and the blood-pressure lowering medicine. Hydralazine and Verapamil. the period of blood-pressure lowering was kept and I can conclude that in case of joint-use of Furosemide, a kind of good urinization. the effect of urinization by Furosemide is increased, but that of Hydrochlorothiazide is disturbed.

• Korean Journal of Family Social Work
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• no.59
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• pp.5-26
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• 2018

This study aims to examine the mediating effect of parental monitoring and child's self-esteem on the relationship between parental time and child's life satisfaction in single mother families. For this purpose, MOGEF (Ministry of Gender Equality and Family)'s 'Research data of adolescents in 2015' was used and 117 single mothers and their children aged 9 to 18 were selected for the analysis. Structural Equation model analysis reveals that adolescent's self-esteem has a mediating effect on the relationship between parental time and adolescent's life satisfaction, though parental time and parental monitoring have no significant effect on adolescent's life satisfaction. With these results, policy suggestions to support single mothers' parental time were proposed.

• Toxicological Research
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• v.19 no.3
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• pp.173-180
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• 2003

The present study was conducted to investigate the single and 2-week repeated dose toxicity of red ginseng acidic polysaccharide (RGAP) in Sprague-Dawley rats. The test article was administered orally to rats at dose levels of 0, and 2000 mg/kg/day for single dose toxicity study and at dose levels of 0, 250, 500, and 1000 mg/kg/day for repeated dose toxicity study. In both studies, there were no treatment-related effects on mortality, clinical signs, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings and organ weights of all animals treated RGAP. Based on these results, it was concluded that the 2-week repeated oral dose of RGAP may have no toxic effect in rats at a dose level of 1000 mg/kg/day. In the condition of this study, the no-observed-adverse-effect level (NOAEL) was considered to be 1000 mg/kg/day for both sexes.

• Journal of Magnetics
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• v.19 no.1
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• pp.10-14
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• 2014

In this study, we fabricate an integrated microfluidic chip with a planar Hall effect (PHE) sensor for single magnetic bead detection. The PHE sensor was constructed with a junction size of $10{\mu}m{\times}10{\mu}m$ using a trilayer structure of Ta(3 nm)/NiFe(10 nm)/Cu(1.2 nm)/IrMn(10 nm)/Ta(3 nm). The sensitivity of the PHE sensor was 19.86 ${\mu}V/Oe$. A diameter of 8.18 ${\mu}m$ magnetic beads was used, of which the saturation magnetization was ~2.1 emu/g. The magnetic susceptibility ${\chi}$ of these magnetic beads was calculated to be ~0.14. The diluted magnetic beads solution was introduced to the microfluidic channel attributing a single bead flow and simultaneously the PHE sensor voltage was measured to be 0.35 ${\mu}V$. The integrated microchip was able to detect a magnetic moment of $1.98{\times}10^{-10}$ emu.

• Journal of Embryo Transfer
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• v.13 no.2
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• pp.127-137
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• 1998

This experiment was carried out to investigate the factors affecting superovulation in rabbits and to determine the effect of pFSH and PMSG on ovarian superovulatory responses and embryo production, and the effect of superovulation treatment with a single injection of pFSH dissolved in polyvinylpyrrolidone on the ovarian responses and the embryo quality. The results obtained were suonmerized as follows: Superovulatory response resulted in significantly (P<0.05) higher ovulation rates and more embryos in spring or autumn, compared with summer or winter. Repeated superovulatory treatments with PMSG leaded to a significantly(P<0.05) decreased number of total follicles and recovered ova. Superovulation with pFSH resulted in the higher number of ovulated follicles and recovered ova than with PMSG. A single subcutaneous injection of pFSH dissolved in 25% PVP resulted in the more ovulation points(33.2) and recovered embryos(30.2), which were comparable to the multiple injections of pFSH(44.8 vs 37.7).These results indicated that the treatment with a single injection of FSH dissolved in PVP was an efficient and simple alternative method to the conventional multiple FSH injections for superovulation in rabbits.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.35 no.3
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• pp.333-340
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• 2011

We evaluated the stress-reduction effect for different shapes of a composite adherend with or without a spew fillet. Six different single-lap joint specimens were modeled and assessed using nonlinear finite element analysis. Moreover, we investigated the effect of the stiffness ratio of the adherend and adhesive. The single-lap joint with normal tapering had the highest stress values, and the single-lap joint with reverse tapering and a spew fillet had the lowest stress values. The composite adherends with higher stiffness had lower stress values, and the adhesives with lower stiffness had lower stress values.

• Women's Health Nursing
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• v.22 no.4
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• pp.210-220
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• 2016

Purpose: The purpose of this study was to construct and test a structural equation modeling on the reproductive health behavior of single women with sexual experiences. This study employed Ajzen's Theory of Planned Behavior (TPB). Methods: The data were collected after receipt of consent from 250 single women with sexual experiences, and analyzed using SPSS 18.0 and AMOS 18.0. Results: Model fit indices for the hypothetical model were suitable for the recommended level: $x^2=362.407$, RMR=0.065, RMSEA=0.070, GFI=0.867. TLI=0.927, CFI=0.938, IFI=0.939, and $x^2/dF=2.237$. Intention showed direct effect with the biggest effect being on reproductive health behavior. Attitude, subjective norm and perceived behavioral control were found to have a direct effect on intention. Among them, perceived behavioral control revealed the largest influence. Conclusion: This study suggests that the TPB is a suitable model in explaining the reproductive health behavior of single women with sexual experience. Strategic plans for educational and intervention programs should be aimed to encourage single women to engage in reproductive health behavior.

• Toxicological Research
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• v.20 no.2
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• pp.123-129
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• 2004

The present study was conducted to investigate the single and 2-week repeated dose toxicity of DHP2, a hydrophobic drug delivery vehicle, in ICR mice. The test article was administered orally to mice at the dose levels of 2.5, 12.5 and 37.5 g/kg for single dose toxicity study and at the dose levels of 0, 2.5, 5, and 10 g/kg for repeated dose toxicity study. In both studies, there were no treatment-related effects on mortality, clinical signs, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings and organ weights of all animals treated DHP2. Based on these results, it was concluded that the 2-week repeated oral dose of DHP2 may have no toxic effect in mice at a dose level of 10 g/kg. In the condition of this study, the no-observed-adverse-effect level (NOAEL) was considered to be 10 g/kg/day for both sexes.

• The Korean Journal of Community Living Science
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• v.22 no.4
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• pp.557-572
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• 2011

This study examines the effect of adult-children support network on the psychological well-being of the single and couple elderly households in rural areas. Adult-children support networks include both structural and functional characteristics. For the purpose of this research, 476 participants, who are older than 60 years old, living in rural areas, were selected. The results of this study are summarized as follows: the average degree of psychological well-being of the rural elderly was high. Emotional support from adult children was higher than economic or instrumental support. In the case of the single elderly households, adult children's economic support was the strongest variable affecting the psychological well-being. In the case of the couple elderly households, adult children's emotional support had the greater effect on psychological well-being. On the basis of this analysis, policy implications regarding the single and couple elderly households in rural areas were discussed.

• Journal of the Korean Society of Propulsion Engineers
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• v.12 no.4
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• pp.7-15
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• 2008

In manufacturing aircraft, safety and lightness of structure are important factors. Utilizing autofrettage technique, these benefits can be obtained. This technique is most frequently applied to a single cylinder. However, the Bauschinger effect reduces the benefits of autofrettage process Therefore, there is increasing interest in the use of compound cylinder that combine shrink fit and autofrettage. In this paper, single and compound cylinders that has same geometry were considered. It was found that compound cylinder which was autofrettaged has lower tangential hoop stress and plastic strain than single cylinder at bore. This means a reduction in the impact of the Bauschinger effect after shrink-fitting which produces the beneficial bore hoop stress.