• Journal of the Korean Society of Visualization
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• v.20 no.3
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• pp.19-26
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• 2022

In droplet microfluidics, precise droplet manipulation is required in numerous applications. This study presents ultrasonic surface acoustic wave (USAW)-based microfluidic device for label-free droplet separation based on size. The proposed device is composed of a slanted-finger interdigital transducer on a piezoelectric substrate and a polydimethylsiloxane microchannel placed on the substrate. The microchannel is aligned in the cross-type configuration where the USAWs propagate in a perpendicular direction to the flow in the microchannel. When droplets are exposed to an acoustic field, they experience the USAW-induced acoustic radiation force (ARF), whose magnitude varies depending on the droplet size. We modeled the USAW-induced ARF based on ray acoustics and conducted a series of experiments to separate different-sized droplets. We found that the experimental results were in good agreement with the theoretical estimation. We believe that the proposed method will serve as a promising tool for size-based droplet separation in a label-free manner.

• Journal of Korean Port Research
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• v.12 no.1
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• pp.75-86
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• 1998

To design a coastal structure in the nearshore region, engineers must have means to estimate wave climate. Waves, approaching the surf zone from offshore, experience changes caused by combined effects of bathymetric variations, interference of man-made structure, and nonlinear interactions among wave trains. This paper has attempted to find out the effects of two of the more subtle phenomena involving nonlinear shallow water waves, amplitude dispersion and secondary wave generation. Boussinesq-type equations can be used to model the nonlinear transformation of surface waves in shallow water due to effect of shoaling, refraction, diffraction, and reflection. In this paper, generalized Boussinesq equations under the complex bottom condition is derived using the depth averaged velocity with the series expansion of the velocity potential as a product of powers of the depth of flow. A time stepping finite difference method is used to solve the derived equation. Numerical results are compared to hydraulic model results. The result with the non-linear dispersive wave equation can describe an interesting transformation a sinusoidal wave to one with a cnoidal aspect of a rapid degradation into modulated high frequency waves and transient secondary waves in an intermediate region. The amplitude dispersion of the primary wave crest results in a convex wave front after passing through the shoal and the secondary waves generated by the shoal diffracted in a radial manner into surrounding waters.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.451-454
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• 2006

This paper describes the results of cold flow test and hot firing tests of an uni-element coaxial swirl injector and hot firing tests of a subscale combustor, as to the development effort of coaxial swirl injector for high performance liquid rocket engine combustor. A major design parameter for coaxial swirl injector is the recess number of a bi-swirl injector. The results of hot firing tests of the uni-element injector combustor and the sub-scale combustor are analyzed to investigate the effect of the recess number influencing on the combustion performance and pressure fluctuation. The test results of a cold flow test of the unielement combustor shows that it was shown that the change in recess number has significant effect on mixing characteristics and efficiency, while the effect of recess number on atomization characteristic is not The results of a series of firing tests using unielement and subscale combustor show that the recess length significantly affects the hydraulic characteristics, the combustion efficiency, and the dynamics of the liquid oxygen/kerosene bi-swirl injector. As a point of combustion performance, combustion efficiencies are 90% for unielement combustor and 95% for subscale combustor. The difference in the characteristic velocities between the unielement combustor and the subscale combustor may be caused by the difference in thermal loss to the combustor wall and the relative lengths of the combustion chamber. For a mixed type coaxial swirl combustor, the pressure drop across the injector increases as recess number becomes larger. The low frequency pressure fluctuation observed in unielement combustor can be related to the propellant mixing characteristics of the coaxial bi-swirl injector. The effect of the recess number on the pressure fluctuation inside the combustion chamber is more significant in un i-element combustor than the subscale combustor, of which the phenomena are also observed in time domain and frequency domain.

• Journal of Environmental Science International
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• v.19 no.1
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• pp.115-124
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• 2010

Urban watershed can be found in the visible changes in technology, the most realistic satellite images is to use the data. Satellite image data on the indicators for progress on the nature of the change of land use is consistent and repetitive information, regular observation makes possible the detailed analysis of space-time. These remote sensing techniques and the type of course and, by using the time series history, the past, the dynamic model and the randomized prediction methodology for the conversion process if the city and river basin cooperation of the space changes effectively will be able to extrapolate. For each of the main changes in river flow, depending on the area of urbanization as determined according to reproduce the duration of the relationship between the urbanization of the area and runoff can be represented as a linear polynomial expression was, if a linear expression in the two fast slew rate of 0.858 to 0.861 showed up, and fast slew rate of 0.934 to 0.974 for the polynomial are reported. Change of land use changes in the watershed of the flow is one of the most affecting elements. Therefore, changes in land use of the correct classification of rivers is a more accurate calculation of the amount of the floodgate. In particular, using the Landsat images through the image of the land use category, land use past data and calculated using the Markov Chain model and predict the future land use plan in the water control project will be used for large likely.

• Journal of Korean Society of Steel Construction
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• v.23 no.3
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• pp.295-304
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• 2011

Bracket-type connection is often used for the weak-axis steel connection. In general, a beam-to-column connection for the bracket type is fabricated at the shop and abeam splice is additionally attached to the bracket in the site. Therefore, steel construction would not be competitive due to the increase of beam splice fabrication cost and overall construction period. This paper now proposes the new weak-axis connection types without a scallop, which has more definite strength flow, simple connection details, and better workability. From the series of experiments, the proposed connections showed better strength and ductility in comparison with standard details with scallop because the thickness of the welding plate for wide-flanged, beam-to-column connection can be easily adjusted.

• Korean Journal of Remote Sensing
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• v.37 no.6_2
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• pp.1891-1900
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• 2021

Fine particulate matter (FPM; diameter ≤ 2.5 ㎛) is frequently found in metropolitan areas due to activities associated with rapid urbanization and population growth. Many adolescents spend a substantial amount of time at school where, for various reasons, FPM generated outdoors may flow into indoor areas. The aims of this study were to estimate FPM concentrations and categorize types of FPM in schools. Meteorological and chemical variables as well as satellite-based aerosol optical depth were analyzed as input data in a random forest model, which applied 10-fold cross validation and a grid-search method, to estimate school FPM concentrations, with four statistical indicators used to evaluate accuracy. Loose and strict standards were established to categorize types of FPM in schools. Under the former classification scheme, FPM in most schools was classified as type 2 or 3, whereas under strict standards, school FPM was mostly classified as type 3 or 4.

• Proceedings of the Korean Society of Toxicology Conference
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• 2006.11a
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• pp.65-74
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• 2006

Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

• Journal of Korean Society of Environmental Engineers
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• v.34 no.4
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• pp.223-231
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• 2012

The purpose of this study is to investigate basically the mechanism of heat transfer by the resolution of complex fluid flow inside a sophisticated designed screw dryer for the treatment of sewage sludge by using numerical analysis and experimental study. By doing this, the result was quite helpful to obtain the design criteria for enhancing drying efficiency, thereby achieving the optimal design of a multiple screw type dryer for treating inorganic and organic sludge wastes. One notable design feature of the dryer was to bypass a certain of fraction of the hot combustion gases into the bottom of the screw cylinder, by the fluid flow induction, across the delicately designed holes on the screw surface to agitate internally the sticky sludges. This offers many benefits not only in the enhancement of thermal efficiency even for the high viscosity material but also greater flexibility in the application of system design and operation. However, one careful precaution was made in operation in that when distributing the hot flue gas over the lump of sludge for internal agitation not to make any pore blocking and to avoid too much pressure drop caused by inertial resistance across the lump of sludge. The optimal retention time for rotating the screw at 1 rpm in order to treat 200 kg/hr of sewage sludge was determined empirically about 100 minutes. The corresponding optimal heat source was found to be 150,000 kcal/hr. A series of numerical calculation is performed to resolve flow characteristics in order to assist in the system design as function of important system and operational variables. The numerical calculation is successfully evaluated against experimental temperature profile and flow field characteristics. In general, the calculation results are physically reasonable and consistent in parametric study. In further studies, more quantitative data analyses such as pressure drop across the type and loading of drying sludge will be made for the system evaluation in experiment and calculation.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.5
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• pp.61-68
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• 2020

In this study, the international standard ISO TS 16774 Part 3 Test Method for Water (wash out) Resistance and KS F 4935 ｢Sealant Injection type for water leakage maintenance of adhesive flexible rubber asphalt series｣, which are standardized as a quality control method of injection type repair materials used for water leakage cracks in underground concrete structures, are currently used in Korea. As a result, considering the performance criteria of "mass change rate -0.1%" stipulated in KS F 4935, the remaining 13 types repair materials, excluding RG-2 of synthetic rubber and UG-1 of urethane, need to be reviewed for stabilization of the loss resistance due to the flow of ground water. The results of this study are determined to be available as a basic indicator for the selection of repair materials used for cracks in concrete structures. In addition, it is expected that the results of this study can be utilized as reference data that can be reflected in the improvement of the quality of repair materials that will be researched and developed later.

• Journal of Oral Medicine and Pain
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• v.30 no.4
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• pp.383-389
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• 2005

Xerostomia is defined as a subjective complaint of dry mouth that may be perceived when there is insufficient mucosal wetting. However, the diagnosis and treatment of xerostomia is not that simple because of the fact that the subjective awareness of dry mouth is not always correlated with a diminution in the flow of saliva and there is always a difference between individuals in salivary flow rates needed for normal oral function. In the present study, the aim was to develop a questionnaire to evaluate the dry mouth symptoms and to analyze its reliability and usability as a diagnostic and analytic tool for xerostomia. The questionnaire which consists of 6 Visual Analogue Scale(VAS) type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to avoid oral dryness was developed and administered twice with 1 week's interval to the healthy 88 young adults without dry mouth symptoms(44 males and 44 females; mean age was $25.6{\pm}3.1$ years in male and $24.3{\pm}2.1$ years in female). The results were as follows. 1 The intraclass correlation coefficients of 6 questions to evaluate the subjective oral dryness were as significantly high as 0.767 for the degree of oral dryness at other times of the day, 0.850 for the amount of saliva in the mouth, and 0.791 for the degree of effect on daily life due to oral dryness and as high as 0.563 for the degree of oral dryness at night or on awakening, 0.674 for the degree of oral dryness during eating, and 0.641 for the degree of difficulty in swallowing foods. 2. Cronbach's alpha value of 6 questions was 0.982. It can be concluded that the series of questions to evaluate the subjective oral dryness has high internal consistency. 3. Cohen's kappa values of 4 questions to evaluate behavior to relieve oral dryness were as significantly high as 0.850 for the frequency of keeping a glass of water at the bedside and as high as 0.506 the frequency of awakening during sleeping due to oral dryness, 0.419 for the frequency of sipping liquids to aid in eating dry foods, and 0.407 for the frequency of using a candy or chewing gum due to oral dryness. From the results, it can be concluded that the questionnaire consisting of 6 VAS type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to relieve oral dryness has reliability of good to excellent level, and that the series of 6 VAS type questions has significantly high internal consistency to evaluate the subjective oral dryness.