• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권3호
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• pp.137-145
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• 2009

As an efficient controlled release system for rhBMP-2, a functional nanoparticle-hydrogel complex, incorporated with matrix metalloproteinase(MMP) sensitive peptide cross-linker, was developed and used as a bone transplant. In vivo bone formation was evaluated by soft x-ray, histology, alkaline phosphatase(ALP) activity and mineral contents analysis, based on the rat calvarial critical size defect(8mm in diameter) model. Significantly, effective bone regeneration was achieved with the rhBMP-2 loaded MMP sensitive hyaluronic acid(HA) based hydrogel-Nanoparticles(NP) complex, as compared to only MMP HA, the MMP HA-NP without rhBMP-2, or even with the rhBMP-2. These improvements included the formation pattern of bone and functional marrow, the degree of calcium quantification, and the ALP activity. These results indicate that the MMP sensitive HA with nano-particle complex can be a promising candidate for a new bone defect replacement matrix, and an enhanced rhBMP-2 scaffold.

• Journal of Microbiology
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• 제45권4호
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• pp.358-363
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• 2007

Multi-drug resistant Pseudomonas aeruginosa has been implicated in a variety of serious therapeutic problems in clinical environments. Among the 968 P. aeruginosa isolates obtained from two hospitals in Daegu, Korea, we acquired 17 isolates that were resistant to all available tested antimicrobial agents, with the exception of colistin (colistin-only sensitive). We characterized the antimicrobial susceptibilities, $metallo-{\beta}-lactamases$, and epidemiological relatedness among the colistin-only sensitive P. aeruginosa isolates. All colistin-only sensitive isolates were positive in the modified Hodge test and imipenem-EDTA synergy test, thereby indicating the production of $metallo-{\beta}-lactamases$. 11 isolates from the secondary hospital and six isolates from the tertiary teaching hospital harbored $bla_{VIM-2}$ and $bla_{IMP-1}$, respectively. The pulsed-field gel electrophoretic analysis of the SpeI-digested DNA from P. aeruginosa isolates indicated that two different clones of colistin-only sensitive P. aeruginosa originated from each hospital, and had spread within the hospital environment. Overall, colistin-only sensitive P. aeruginosa was detected in Korea for the first time, but no pan-drug resistant bacteria were identified. Nationwide surveillance is required in order to monitor the emergence of colistin-only sensitive or pan-drug resistant bacteria.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.1686-1687
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• 2011

A microfabricated chip with in-channel electrochemical cell using interdigitated gold electrode was fabricated for sensitive electrochemical analysis. The gold electrodes were fabricated on glass wafer using thermal evaporator and were covered using PDMS mold containing microchannel for analyte and electrolyte. The active area of each electrode was $250\;{\mu}m{\times}200\;{\mu}m$ with a gap of 200 ${\mu}m$ between the electrodes. Microelectrodes results in maximum amplification of signal, since the signal enhancement effect due to cycling of the reduced and oxidized species strongly depends on the inter electrode distance. Analytes such as methylene blue and guanosine were characterized using the fabricated electrodes and their electrochemical characteristics were compared with conventional bulk electrodes. The device so developed shall find use as disposable electrochemical cell for rapid and sensitive analysis of electroactive species.

• 대한산업공학회지
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• 제4권2호
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• pp.91-96
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• 1978

A modeling framework and its computational methodology for an industrial sector of the economy are investigated. The suggested industrial sector model is characterized by a programming (process analysis) representation of a production sector and an econometric estimation of the price sensitive (own and cross-prices) demands. By introducing the price sensitive demands into the process analysis representation of the production sector, it becomes possible to analyze and plan the pricing policy, the optimal production schedules and capacity expansion plans within a single framework. The computational scheme suggested in the report is based on the iterative approach each of which solves a separable convex programming problem.

• 한국생활과학회지
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• 제14권5호
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• pp.785-794
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• 2005

This is an empirical research on the effect of the product placement advertisement on the consumption behavior of college students. A structured survey to 342 students in and near Seoul shows that life style of the students significantly matters to the effect. That is, beauty-oriented students are more sensitive to the PPL than other student groups (i.e., career-oriented, saving-oriented, leisure-oriented, or freedom-oriented students). On the other hand, the freedom-oriented students are not sensitive to the PPL at all. Some statistical methods including factor analysis and multiple regression analysis were employed in order to get those results.

• 대한기계학회논문집A
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• 제24권7호
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• pp.1795-1800
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• 2000

One of the principal sources of vibration and noise in permanent magnetic machines is cogging torque, which is induced by interaction between the rotor poles and the stator teeth. For its analysis, using finite element analysis is very time consuming and the calculation of performance factors is extremely sensitive to the discretization. Especially, Maxwell stress tensor method is sensitive to the location of integral path. In this paper, a cogging permeance fuction is defined and replaced by the straight line. And it is assumed that the flux density acting on the stator's tooth side is the euqal to the flux density of the slot area. Using this definition and assumption, analytical calculation of cogging torque is presented and validated. And several reduction method is introduced.

• 한국의류산업학회지
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• 제13권3호
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• pp.364-372
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• 2011

The primary purposes of this study were to classify consumer's type according to narcissistic orientation of consumer and then to reveal consumer's perception differences on consumption value of apparel products and cosmetics subject to the types. Data were collected from 194 female college students in Ulsan. It was analyzed by frequency analysis, factor analysis, cluster analysis and MANOVA, ANOVA using SPSS Win 12.0. The results were as follows: First, consumer's types classified according to narcissistic orientation were non-narcissist, high-narcissist, leadership and self-absorption. Second, in the consumption value of apparel products case, there were significant differences in effective value, symbolic value and sensitive value among the types. Third, in the consumption value of cosmetics case, there were significant differences in sensitive value and effective value among the types.

• 분석과학
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• 제14권6호
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• pp.510-515
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• 2001

There has been an increasing need for analytical methods of dissolved total iron (tFe) that are highly sensitive, rapid, inexpensive and simple for environmental samples. A sensitive flow injection analysis (FIA) method for determining the concentration of tFe in environmental samples was developed. The proposed method required 10 minutes and only $500{\mu}L$ of sample for and analysis. The standard deviation was 5.0% at $0.5{\mu}gL^{-1}$ (n=6), and the detection limit was $0.075{\mu}gL^{-1}$. The developed method was applied to environmental samples such as tap water, mineral water, rain, snow and cloud water. Since this FIA system was free form interferences of coexisting ions commonly found in samples, sub-${\mu}gL^{-1}$ level of tFe could be easily determined without further preconcentration and separation.

• Structural Engineering and Mechanics
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• 제60권6호
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• pp.1093-1117
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• 2016

Global sensitivity analysis (GSA) has been widely used to investigate the sensitivity of the model output with respect to its input parameters. In this paper a new single-solution search optimization algorithm is developed based on the GSA, and applied to the size optimization of truss structures. In this method the search space of the optimization is determined using the sensitivity indicator of variables. Unlike the common meta-heuristic algorithms, where all the variables are simultaneously changed in the optimization process, in this approach the sensitive variables of solution are iteratively changed more rapidly than the less sensitive ones in the search space. Comparisons of the present results with those of some previous population-based meta-heuristic algorithms demonstrate its capability, especially for decreasing the number of fitness functions evaluations, in solving the presented benchmark problems.

• 한국IT서비스학회지
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• 제21권3호
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• pp.1-25
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• 2022

The financial MyData service has implemented in January 2022 and launched 45 services by banks, securities, credit cards and fintech companies. This study applied the Q methodology, to identify the user types of MyData services and compared the perceptions of employees of financial institutions who plan and develop the MyData services. There are three types of MyData service users: active users, limited users who focus on consumption and asset status inquiry, and sensitive users for personal information. There were two types of recognition of financial company employees. One is the active user support other is the sensitive user for personal information support. The analysis of subjective perceptions can be used as a reference for establishing a company's MyData service marketing strategy and establishing related policies to improve the MyData ecosystem.