Proceedings of the KIEE Conference (대한전기학회:학술대회논문집)

The Korean Institute of Electrical Engineers (대한전기학회)
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Microfluidic platform for voltammetric analysis of biomolecules

Microfludic 플랫폼을 이용한 생체 분자의 voltammetric 분석

  • Chand, Rohit (Dept. of Nano Science and Engineering, Myongji University) ;
  • Han, Da-Woon (Dept. of Nano Science and Engineering, Myongji University) ;
  • Jha, Sandeep K. (Dept. of Nano Science and Engineering, Myongji University) ;
  • Kim, Yong-Sang (Dept. of Nano Science and Engineering, Myongji University)
  • ;
  • 한다운 (명지대학교 나노공학과) ;
  • ;
  • 김용상 (명지대학교 나노공학과)
  • Published : 2011.07.20
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Abstract

A microfabricated chip with in-channel electrochemical cell using interdigitated gold electrode was fabricated for sensitive electrochemical analysis. The gold electrodes were fabricated on glass wafer using thermal evaporator and were covered using PDMS mold containing microchannel for analyte and electrolyte. The active area of each electrode was $250\;{\mu}m{\times}200\;{\mu}m$ with a gap of 200 ${\mu}m$ between the electrodes. Microelectrodes results in maximum amplification of signal, since the signal enhancement effect due to cycling of the reduced and oxidized species strongly depends on the inter electrode distance. Analytes such as methylene blue and guanosine were characterized using the fabricated electrodes and their electrochemical characteristics were compared with conventional bulk electrodes. The device so developed shall find use as disposable electrochemical cell for rapid and sensitive analysis of electroactive species.

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