Background: Korean Red Ginseng-a steamed root of Panax ginseng Meyer-has long been used as a traditional medicine in Asian countries. Its antipruritic effect was recently found, but no molecular mechanisms were revealed. Thus, the current study focused on determining the underlying molecular mechanism of Korean Red Ginseng extract (RGE) against histamine-induced itch at the peripheral sensory neuronal level. Methods: To examine the antipruritic effect of RGE, we performed in vivo scratching behavior test in mice, as well as in vitro calcium imaging and whole-cell patch clamp experiments to elucidate underlying molecular mechanisms. Results: The results of our in vivo study confirmed that RGE indeed has an antipruritic effect on histamine-induced scratching in mice. In addition, RGE showed a significant inhibitory effect on histamine-induced responses in primary cultures of mouse dorsal root ganglia, suggesting that RGE has a direct inhibitory effect on sensory neuronal level. Results of further experiments showed that RGE inhibits histamine-induced responses on cells expressing both histamine receptor subtype 1 and TRPV1 ion channel, indicating that RGE blocks the histamine receptor type 1/TRPV1 pathway in sensory neurons, which is responsible for histamine-dependent itch sensation. Conclusion: The current study found for the first time that RGE effectively blocks histamine-induced itch in peripheral sensory neurons. We believe that the current results will provide an insight on itch transmission and will be helpful in understanding how RGE exerts its antipruritic effects.
This paper is based on a survey of consumers 'opinions on underwears. The questions in the survey dealt with what materials were used to manufacture underwears, which underwears were worn together in combinations, and how comfortable underwears were. In addition, the respondents were asked about how many pieces of different underwears they posses. Through such research, this paper aims to provide a guide to manufacturing domestic underwears that are competitive against foreign bands. 336 women in their twenties, thirties, forties and fifties from Seoul and it's suburbs were surveyed. Statistical analysis was performed by calculating the average, frequency and standard deviation, and through one-way analysis and the Duncan test. The following are the results of the study : 1. Consumers were moderately satisfied with Korean-made underwears. In order to complete with foreign brands, products with high consumer-satisfaction levels must be produced. 2. Upper garments usually consisted of brassieres with shoulder straps and sleeveless shirts. For lower underwears, most people tended to wear panties under girdle, with garlets on top. This is most likely the resut of more people wearing slacks than skirts. 3. Consumer in their twenties had anaverage of 1.71 slips, while those in their thirties had 3.07, those in their forties and 3.25, and people in their fifties had 3.88 slips. Thus the number of slips a consumer possesses increases as age increases. for socks, people in their twenties had 7.4 pairs on average, those in their thirties had 5.5, those in their forties had 6.7, and those in their fifties had 5.3. Thus, those in their twenties possessed the most number of socks. Consumers in their twenties also had the largest proportion of socks among all the types of hosiery combined, with 47.1% of their hosiery being socks. 4. Consumers did tend to prefer cotton underwears, but according to the type of underwears, producting using mixed fabrics of cotton and synthetic fibers were also frequently worn. 5. The shape and form of underwear that consumers prefer in a ceratin time frame varies according to the latest fashion in outer wear. Therefore, planning design of underwear products by predicting the future trend of outer wear fashion is necessary.
Kim, Doo-Sup;Rah, Jung-Ho;Chung, Hoe-Jeong;Shin, John Junghun;Hong, Kyung-Jin
Clinics in Shoulder and Elbow
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v.17
no.4
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pp.181-184
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2014
Schwannomas are soft tissue sarcomas arising from neurilemma of Schwann cells in peripheral nerves, and is the most frequent type of benign tumor found in these nerves. We report a case of a Schwannoma of the ulnar nerve in the elbow joint, and along this report, give a review of the literature. A 46-year-old male patient was hospitalized with complaints of swelling and pain in the left elbow and a tingling sensation and hypoesthesia of the fourth and fifth fingers. Physical examination of the patient showed he was positive for Tinel's sign, and magnetic resonance imaging results demonstrated the presence of a Schwannoma. Subsequent biopsy and excision of the Schwannoma was carried out. The suspected mass, which had a clear margin separating it from the healthy nerve of the medial left elbow, was removed along with its $2{\times}2{\times}3cm$ capsule after a histological diagnosis of a Schwannoma was made. Pathophysiological results confirmed the excised mass as a Schwannoma. Schwannoma of the ulnar nerve within the elbow joint is rare and differential diagnosis is difficult. Therefore, treatment can only proceed after the presence of Schwannoma has been confirmed by physical and radiological examinations.
This research was designed to investigate the preference for underwear and textiles of college students according to season. One hundred and nine subjects majoring in fashion design were surveyed about the most favorite materials among underwear textiles according to each season. The extent of preference was compared by season. The results of this study were as follows: 1. The most important purpose of wearing underwear was the hygienic performance in summer and the insulation in winter. 2. The most favorite textile of underwear was cotton regardless of season and the most favorite type of underwear was fashionable underwear in summer and insulating underwear in winter. 3. The most preferred material underwear was white jacquard knitted with cotton 30's yarn for summer and white and gray melange plain knit made with cotton and polyester blended 38's syro-spunned yarn for winter. 4. From the results about the factors influencing on the preference for the textiles of underwear, color, touch and cool sensation were the positive factor in summer, while insulation and pattern were comparatively affirmative factor in winter. 5. From the results about the sensibility factors influencing on the preference for the textiles of underwear, 'comfort', 'refined', 'naive' were the positive factor in summer, while 'comfort', 'naive', 'refined' were comparatively affirmative factor in winter. From the above results, hygienic and fashionable underwear is required in summer and thin and insulating underwear in winter for young people. Additionally, in textiles, cotton and cotton blended, comparatively light and simple patterned material is recommended for underwear.
The construction of an athlete's tight-fitting garments is very important to the wearer in terms of athletic performance. Therefore pattern development of tight-fitting garments must allow for the full range of human movement and postures. In this study the relationship between the construction of a skate pants pattern and clothing fitting was explored with the aim of improving the comfort of the clothing. The four male subjects were university students between the ages of 20 to 24. Subjective wear sensations of the experimental garments were rated using a seven-point Likert scale on four consecutive days. While wearing the garments, subjects were asked to take five different postures including waist flexion, sitting and others. A Likert-type scale was used for the evaluation, with 7 points indicating the best fit in tight-fitting pants. Results showed differences in the front-rise length and back-rise length between basic pants(A) and modified pants(B,C,D) were -5.16cm and +5.64cm. Comparing the basic pants pattern(A) with modified pants pattern(B), the latter was superior to basic pants(A) in terms of pressure sensation and closeness of fit, but there was no significant difference. Among the four tight-fitting skate pants, A and B pants were superior to the others in terms of fitting and stability of waist and hip sections. In the case of the skate pants, the number of cutting lines in the pattern had an influence on clothing comfort. A minimum cutting line for tight skate pants was better than a maximum cutting line in terms of clothing comfort.
I-phone presented a new mobile control type by the introducing motion recognition sensor and that influenced on game application development so that led a lot of games using kinds of sensors. In this paper, we divided the game enjoyment into 5 factors for the embodiment of the sensor's influence direction on the enjoyment. We experimented two game, which have same content, different devices in using motion recognition sensor or not for clarifying the distinction between devices. As a experiment source game, we used Cooking Mama, as a experimental device, we used I-pod touch and NDS. This experiment shows a motion recognition sensor control's enjoyment is far superior to touch sensor. This sensor got high marks on every fun factors, stimulus, absorption, empathy, accomplishment and variation. Especially, stimulus and empathy showed great differences. In this case, we found the fact that extended communication between the gamer and the device can be fun.
This study has intended to suggest fundamental data to develope and choose appropriate shoes for upland farming in order to prevent health deterioration of women workers and improve work effectiveness and reduce fatigue by wearing appropriate shoes. During 1995. 4. 28 - 5. 10, Fifty women workers in hot pepper farming were observed and major shoe types, which were rubber shoes, walking shoes, slippers, and rubber boots, were selected for the study. During 1995. 10. 9 - 31, two subjects were tested by wearing those shoes in the laboratory where the temperature was 24$\pm$1$^{\circ}C$ and relative humidity 50$\pm$5%RH. And the temperature & humidity on sole and in the shoes, the rectal temperature, skin temperature, blood pressure, pulse, lactate concentration of blood, Flickers' value and subjective sensation were measured. The results were as follows : 1. 84% of women workers mentioned that they need shoes improvement and the order of most frequent shoe types to be worn was rubber shoes, walking shoes, slippers, rubber boots. 2. The rate of women who were unsatisfied with shoes for upland farming is 38 percentages. The reason of unsatisfaction was that feet were in a sweat and alien substances were let into shoes. 3. The temperature & humidity on sole were the lowest in rubber boots during experiment(p<0.01). 4. The relative humidity in the shoes was the highest in rubber boots by 90% and the lowest in walking shoes by 72% during rest And the humidity in slippers and walking shoes were significantly low in experiment(p<0.001). 5. Rubber boots showed the highest rise in rectal temperature by 0.2$^{\circ}C$ showing increase of core temperature (p<0.05). 6. The mean skin temperature during experiment was highest in rubber boots by 33.8$^{\circ}C$(p<0.001).
The Journal of Korean Institute of Communications and Information Sciences
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v.31
no.10C
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pp.964-972
/
2006
The kidney keeps with close relationship in the internal organs, that the kidney function filtering eliminate the wastes to the urine on the processing to replace the old with the new blood. In case of these problem in the kidney, there is no way to catch out with self-awakening symptom except for serious illness. This problem can solve with keeping the systematic diagnosis method in the kidney trouble shooting. Under the circumstances, the importance of the diagnosis for the kidney disease is growing day after day. In this paper, among the great four diagnosises, using the way of ocular inspection & auscultation, we would like to propose rouble shooting in the way of the kidney. To do this, through the assistance of the input image, extract the value of the color with appropriate output, analysing the color of the face with related to the kidney, using the results we would like to get the accurate symptoms on the kidney's problems. Also, through analysing and comparing with the relationship the kidney and the signal of voice, we would like to realize the proof system of human health. Finally, we'd like to make proof of the usefulness for proposed method from this study.
Dashmaa, Dashdorj;Yang, Jieun;Ba, Hoa Van;Ryu, Kyeong-Seon;Hwang, Inho
Food Science of Animal Resources
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v.33
no.4
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pp.508-514
/
2013
Taste-active compounds (e.g., amino acids and nucleotides) play an important role in contribution to the gustatoty sensation of food. The current study aimed to examine the differences in taste-active compounds between different beef muscles, breeds and aging periods. We have chosen the longissimus dorsi and semitendinosus muscles of Hanwoo breed and longissimus dorsi muscle of Angus breed for the investigation of the aforementioned compounds. Hanwoo muscles were aged for 7 or 28 d, and Angus samples were aged for 28 d at $4^{\circ}C$. Results revealed that 8 out of the 18 detected free amino acids (FAA) showed significant (p<0.05) differences between the two Hanwoo muscles. Twelve FAAs showed aging effect (p<0.05) in which the amounts of 8 FAAs significantly increased as aging time increased. Inosine 5-monophosphate (IMP), hypoxanthine (Hx) and inosine showed significant (p<0.05) differences between the Hanwoo muscles, aging resulted in an increase in amounts of these nucleotides. Hanwoo beef had significantly (p<0.05) higher total amount of sweet amino acids than the Angus ones in that 15 amino acids showed differences (p<0.05) between the two breeds. Amounts of guanosine 5-monophosphate (GMP) and Hx were significantly higher (p<0.05) for Angus beef. Current study indicated that muscle type, breed and aging period had large variations in free amino acid and nucleotide contents, which may subsequently affect the taste attributes of cooked beef.
The construction of athlete's tight-fitting garments by reducing the elastic knit pattern is an interesting subject, which directly influences the performance of the wearer. Therefore, relationships between the reduction rates of the men's pants pattern obtained using measurements of Size Korea 2004 and clothing fitting were explored to improve clothing comfort. Two pattern making methods were developed and the reduction rates were applied to those pants depending on the parts of human body. The four male subjects were university students in the ages of 20 to 24. Subjective wear sensations of the experimental garments were rated using seven Likert scales during 4 consecutive days. While wearing the garments, subjects were kept four various postures including waist flexion and sitting etc by requests of the researchers. Likert type scale was used for the evaluation and 7 point indicates that it gave the best fit as tight-fitting pants. As results, differences in the length and girth between two piece pants pattern(style 1) and one piece pants pattern(style 2) were 0.0$\sim$0.3cm. Between two pattern making methods, one piece pants pattern(the style 2) was superior to two piece pants pattern in terms of subjective sensation and fit. Among eight tight-fitting pants, C, D, G, H pants were superior in terms of fitting and stability of waist and hip part to the others. ill case of tight-fitting pants, the reduction rate of the pattern in the course direction, the reduction rate of T2/3(66%) was better than that of T/2(50%), but the reduction rate of the pattern in the wale direction, that of the part of crotch, which was very sensitive part, should be kept the same as suggested earlier by Ziegert(1988).
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