• 대한기계학회논문집
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• 제18권11호
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• pp.2932-2943
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• 1994

An efficient approach to the automatic construction of effective quadrilateral finite element meshes for two-dimensional analysis is presented. The procedure is composed of, firstly, an initial mesh generation and, secondly, an h-version of adaptive refinement based on error analysis. As for an initial mesh generation scheme, a modified looping algorithm has been employed. For the adaptive refinement process, an error indicator obtained by computing the residual error of the equilibrium equations in the energy norm with a relaxation factor has been employed. Examples of mesh generation and self-adaptive mesh improvements are given. These example solutions demonstrate that an effective mesh for a given error tolerance can be obtained in a few steps of the analysis processes.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2005년도 하계학술대회 논문집 Vol.6
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• pp.274-275
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• 2005

The tensile strain dependency of critical current in YBCO coated conductors was examined at 77K and in the self magnetic field. A commercially available YBCO sample with Cu stabilizer layer was supplied. There existed a peak in the relation between the Ie and tensile strain, and the reversible variation of $I_c$ with applied tensile strain was found. In the neutral axis Ni alloy RABiTS-$Y_2O_3$/YSZ/$CeO_2$ buffered YBCO tape, the $I_c$ recovered reversibly until the applied strain reached to about 0.5%, representing that a significant residual compressive strain induced during cooling to 77 K influenced the axial strain tolerance of YBCO conductors. To investigate the strain and stress influence on the $I_c$, the stress-strain characteristics of YBCO conductors measured at 77 K were discussed.

• 한국심리학회지 : 코칭
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• 제4권1호
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• pp.1-19
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• 2020

본 연구에서는 완벽주의적 자기제시와 사회불안의 관계에서 불확실성에 대한 내인력 부족과 이분법적 사고의 이중매개효과를 검증하고자 했다. 연구대상은 서울 소재 성인 남녀 252명 이었다. 완벽주의적 자기제시 척도, 사회적 상호작용 불안 척도, 사회적 공포 척도, 불확실성에 대한 인내력 부족 척도, 개정판 이분법적 사고 지표를 사용하여 자료를 수집하였으며 분석 결과는 다음과 같다. 첫째, 완벽주의적 자기제시와 사회불안의 관계에서 불확실성에 대한 내인력 부족과 이분법적 사고, 각각의 완전 매개효과가 검증되었다. 완벽주의적 자기제시 성향의 개인에게서 사회불안이 발생하고 유지되는데 있어 두 변인의 매개효과가 유의했다. 둘째, 완벽주의적 자기제시와 사회불안의 관계에서 불확실성에 대한 내인력 부족과 이분법적 사고의 관련성이 검증되었다. 즉, 완벽주의적 자기제시가 불확실성에 대한 내인력 부족을 매개로 하여 이분법적 사고를 촉발시키고, 불확실성에 대한 내인력 부족에서 비롯된 부정적인 인지적 편향을 이분법적 사고가 매개하여 사회불안을 발생시키는 것으로 확인되었다. 이에 완벽주의적 자기제시 성향의 개인이 불확실성에 대한 내인력이 부족할 경우에 이분법적 사고에 취약할 수 있으며, 이분법적 사고는 사회불안을 심화시킬 수 있음이 시사되었다. 마지막으로 본 연구의 제한점과 향후 연구 방향을 제언하였다.

• 한국간호교육학회지
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• 제4권2호
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• pp.264-279
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• 1998

This study researches the attitudes of nursing students toward induced abortion. It aims to Identify the structure of subjectivity of nursing students toward induced abortion. As the research method, Q-statements were collected preliminary to the study through in-depth group talking, case study and literature review. For the study, 28 Q-statements were selected. There were 40 students as subjects for the research. The 40 students sorted the 28 statements using the principle of Forced Normal Distribution. The results of the study were as follows : Three attitude types toward induced abortion were derived from Q-Factor analysis by using PC Quanal Program. The first type is called qualified deontology type. The second type is called rational utility type. The third type is called self-centered utility type. 1) Qualified deontology type emphasizes the importance of respect for life. Induced abortion is acceptable within just limit circumstances. 2) Rational utility type has more tolerance limits. There are rationale for induced abortion. Thls type hates becoming the target of criticism because they are single mothers, were rape or had a deformed baby. 3) Self-centered utility type believe that the most important in the world is one's self. This type emphasizes the importance of women's autonomy. And then the woman should be able to decide about abortion, because it is her body, it is her choice. The result of the study suggests that nursing education need more ethical teaching of the importance of human life. Be cause the fundmental concept of nursing is in the preservation of human life and in the respect for life, dignity and the rights of man. Nursing ethics is a essential for nurses.

• 여성건강간호학회지
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• 제28권4호
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• pp.275-285
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• 2022

Purpose: This study explored the experiences of pregnant women with depressed mood participating in a group cognitive behavioral therapy (CBT) program using video communication, based on Beck's cognitive theory. Methods: The participants were six pregnant women out of 13 women who had participated in an 8-session group CBT program using video communication for women with depressed mood (Edinburgh Postnatal Depression score of ≥9). Data were collected from February 20 through March 25, 2021. In-depth individual interviews were conducted through a video conferencing platform at 1 month post-baseline. Thematic analysis was done. Results: Three themes, 10 subthemes, and 38 concepts were derived from experiences of participating in the 4-week group CBT program (twice a week). The first theme, entitled "continuing realization" had subthemes of "a negative and instable self," "a selfish judgment that excludes others," and "a strong belief in self-control." The second theme, entitled "attempt to change for restoration" had subthemes of "shift to rational thinking," "freedom from suppressed beliefs," "tolerance of other people," and "courage for self-expression." The third theme, entitled "departure for a positive life," had subthemes of "emotional healing," "faith in oneself," and "reestablishing the criteria for happiness." Conclusion: Pregnant women with depressed mood expressed that continuing realizations and attempts to change supported their transition toward a positive direction of healing. Thus, they were able to change their distorted thinking into rational thinking through CBT using video communication. These findings support the use of group CBT using video communication with pregnant women who have depressed mood.

• IMMUNE NETWORK
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• 제10권2호
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• pp.46-54
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• 2010

Background: Graft-versus-host disease (GVHD) is initiated when alloreactive donor T cells are primed by host APCs to undergo clonal expansion and maturation. Since there is a controversy regarding the role of nonhematopoietic cells in GVHD, we wanted to investigate the influence of MHC disparity on nonhematopoietic cells on the pathogenesis of GVHD in the MHC-haplomismatched C57BL/6 ($H-2^b$) or DBA/2 $(H-2^b){\rightarrow}$unirradiated ($C57BL/6{\times}DBA/2$) $F_1(BDF_1;\;H-2^{b/d})$ murine model of acute GVHD (aGVHD) or chronic GVHD (cGVHD). Methods: We generated ($BDF_1{\rightarrow}C57BL/6$), ($BDF_1{\rightarrow}DBA/2$), and ($BDF1{\rightarrow}BDF_1$) chimeras and examined GVHD-related parameters and donor cell engraftment in those chimeras. Results: Using this experimental system, we found that 1) severe aGVHD across MHC Ag barrier depends on the expression of nonhematopoietically rather than hematopoietically derived alloAgs for maximal GVHD manifestations; 2) host APCs were sufficient to break B cell tolerance to self molecules in cGVHD, whereas host APCs were insufficient to induce autoimmunity in aGVHD; 3) donor cell engraftment was greatly enhanced in the host with MHC-matched nonhematopoietic cells. Conclusion: Taken together, our results provide an insight into how MHC disparity on GVHD target organs contribute to the pathogenesis of GVHD.

• Journal of the Korean Data and Information Science Society
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• 제28권3호
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• pp.647-658
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• 2017

본 연구의 목적은 대학생의 내현적 자기애와 평가염려 완벽주의가 SNS 중독경향성에 미치는 상대적 영향력과 더불어 내현적 자기애가 SNS 중독경향성에 미치는 영향에 대한 평가염려 완벽주의의 매개효과를 살펴보는 것이다. 연구대상은 대학생 415명으로 이들을 대상으로 질문지 조사를 실시하였다. 자료 분석은 SPSS win 21을 사용하였다. 연구 결과는 다음과 같다. 첫째, 대학생의 조절실패 및 일상생활장애, 부정정서의 회피, 가상세계지향성 및 금단을 가장 잘 설명하는 변인은 착취/자기중심성이었으며, 몰입 및 내성을 가장 잘 설명하는 변인은 과민/취약성으로 나타났다. 둘째, 평가 염려 완벽주의는 내현적 자기애와 몰입 및 내성, 가상세계지향성 및 금단 간의 관계를 부분 매개하는 반면, 내현적 자기애와 조절실패 및 일상생활장애, 부정정서의 회피 간의 매개하지 않는 것으로 나타났다.

• 벤처창업연구
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• 제7권4호
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• pp.55-64
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• 2012

본 연구는 우리나라 소비자의 친환경 제품에 대한 태도와 구매행동에 영향을 미치는 요인을 분석하기 위해 수행되었다. 연구 모델은 가치-태도-행동(V-A-B) 모델에 기초하여 가치와 개성 변수가 친환경 제품에 대한 태도에 영향을 미치며 친환경제품에 대한 태도는 친환경 제품의 구매행동에 영향을 미치는 형태로 구성하였다. 모델에서 가치 변수는 이타주의와 집단주의, 개성 변수로는 우월감과 포용력을 선택하였다. 514개 설문의 분석 결과 이타주의, 집단주의, 포용력은 친환경 제품에 대한 태도에 정(+)의 영향을 미치는 것으로 나타났으나, 우월감은 유의한 영향을 미치지 않는 것으로 나타났다. 그리고 친환경 제품에 대한 태도가 긍정적일수록 친환경 제품을 구매하고 있는 것으로 분석되었다. 소비자가 친환경 제품을 구입할 때 우려하는 요소로는 높은 가격과 친환경 제품의 이익에 대한 불신이 가장 크게 조사되었다. 본 연구의 결과를 바탕으로 그린 마케팅은 친환경 제품의 사회적 가치를 알리고 친환경 제품의 소비자 이익을 신뢰할 수 있는 방법으로 제시하는 것이 중요하다는 것을 강조한다.

• 생명과학회지
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• 제20권5호
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• pp.670-675
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• 2010

Autoimmune regulator gene (Aire)는 흉선에서 발현되며 promiscuous genes으로 알려진 흉선에서 자가항원 발현을 조절한다. Aire 와 promiscuous genes은 흉선에서 T세포 tolerance와 자가면역에 관여한다. 말초 조직 즉 림프절에서 Aire의 역할을 알아보고자 림프절 구성 세포중 하나인 fibroblastic reticular cell (FRC)을 분리 확립하였다. 마우스 림프절로부터 분리된 FRC에서 Aire의 발현을 확인하였고 또한 promiscuous antigen인 insulin의 발현도 확인하였다. Aire 과발현 플라스미드로 형질전환 후 배양 FRC에서 Insulin의 발현이 증가하였다. 이것은 Aire가 FRC에서 promiscuous gene의 발현을 조절한다는 것을 보여주며 peripheral selection과 연관되어 있을 수 있다는 것을 제시한다.

• 원예과학기술지
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• 제34권1호
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• pp.46-54
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• 2016

2-Oxoglutarate (2OG) acts as a signaling molecule and plays a critical role in secondary metabolism in a variety of organisms, including plants. Six 2-oxoglutarate (2OG) and Fe(II) oxygenase (2OGO) genes, VlCE2OGO1 [Vitis labruscana 2-oxoglutarate (2OG) and Fe(II) oxygenase 1], VlCE2OGO2, VlCE2OGO3, VlCE2OGO4, VlCE2OGO5, and VlCE2OGO6, which show different expression patterns upon transcriptome analysis of 'Campbell Early' grapevine exposed to low temperature for 4 weeks, were analyzed for their structure and expression. Comparison of the deduced amino acid sequences of the 2OGO genes from the V. labruscana transcripts revealed sequence similarities of 38.6% (VlCE2OGO1 and VlCE2OGO2) to 19.2% (VlCE2OGO2 and VlCE2OGO3). The lengths of these genes ranged from 1053 to 2298 bp, and they encoded 316 to 380 amino acids. The prediction of the secondary structure of the encoded proteins by Self-Optimized Prediction Method with Alignment (SOPMA) indicated that all the genes contained alpha helix (23.95 to 41.71%), extended strand (16 to 22.34%), beta turn (6.65 to 9.22%), and random coil (32.97 to 51.58%) in the analysis. Specific primers from unique regions in each gene obtained by alignment of nucleotide sequences were used in real time PCR for analysis of gene expression. All tested genes showed differential expression in grapevines exposed to low temperature. Of the six transcripts, VlCE2OGO1, VlCE2OGO2, and VlCE2OGO3 were up-regulated and VlCE2OGO4, VlCE2OGO5, and VlCE2OGO6 were down-regulated in response to cold treatments at all tested time points. The 2OG genes can be used for elucidation of mechanisms of tolerance to cold and as valuable molecular genetic resources for selection in breeding programs for cold-hardy grapevines.