• International Commerce and Information Review
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• v.9 no.1
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• pp.277-295
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• 2007

This paper presents the ODR phenomenon with a specific focus on regulatory problems. It argues that the current regulatory framework for online dispute resolution is, to a large extent, defective. Existing deficiencies result not only from a lack of comprehensive ODR law, but also from the weakness of the other modalities of regulation : norms and market. The current today's approach to regulating ODR has been unsuccessful, and it is time to re-examine that position. I would like to say that suggesting details of the optimal ODR regulatory framework is beyond the scope of this paper. From a broader perspective, the field of ODR seems to be not sufficiently regulated. Neither by law, nor by the restrains set by other norms or market. Given the current weakness of the modalities of regulation, online dispute resolution requires greater institutional and international support. It appears that adoption of internationally harmonized ODR law would not hamper the development of norms and market, but rather support their proper growth. As a result, the co-regulation approach recommended in this paper is different from both traditional state-oriented models of regulation and self-regulatory systems. Arguably, this co-regulation approach is the optimal model for regulation of online dispute resolution under current circumstances.

• Toxicological Research
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• v.26 no.1
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• pp.15-19
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• 2010

Mesenchymal stem cells (MSCs) have greater potential for immediate clinical and toxicological applications, due to their ability to self-renew, proliferate, and differentiate into a variety of cell types. To identify novel candidate genes that were specifically expressed during transdifferentiation of human MSCs to neuronal cells, we performed a differential expression analysis with random priming approach using annealing control primer-based differential display reverse transcription-polymerase chain reaction approach. We identified genes for acyl-CoA thioesterase, tissue inhibitor of metalloproteinases-1, brain glycogen phosphorylase, ubiquitin C-terminal hydrolase and aldehyde reductase were up-regualted, whereas genes for transgelin and heparan sulfate proteoglycan were down-regulated in MSC-derived neurons. These differentially expressed genes may have potential role in regulation of neurogenesis. This study could be applied to environmental toxicology in the field of testing the toxicity of a chemical or a physical agent.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.3
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• pp.872-880
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• 2016

The purpose of this study is to find the research trends relating to flipped learning through keyword network analysis. For investigating this topic, final 100 papers (removed due to overlap in all 205 papers) were selected as subjects from the result of research databases such as RISS, DBPIA, and KISS. After keyword extraction, coding, and data cleaning, we made a 2-mode network with final 202 keywords. In order to find out the research trends, frequency analysis, social network structural property analysis based on co-keyword network modeling, and social network centrality analysis were used. Followings were the results of the research: (a) Achievement, writing, blended learning, teaching and learning model, learner centered education, cooperative leaning, and learning motivation, and self-regulated learning were found to be the most common keywords except flipped learning. (b) Density was .088, and geodesic distance was 3.150 based on keyword network type 2. (c) Teaching and learning model, blended learning, and satisfaction were centrally located and closed related to other keywords. Satisfaction, teaching and learning model blended learning, motivation, writing, communication, and achievement were playing an intermediary role among other keywords.

• BMB Reports
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• v.49 no.10
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• pp.529-535
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• 2016

The NLRP3 inflammasome is activated by a variety of external or host-derived stimuli and its activation initiates an inflammatory response through caspase-1 activation, resulting in inflammatory cytokine IL-1β maturation and secretion. The NLRP3 inflammasome activation is a kind of innate immune response, most likely mediated by myeloid cells acting as a host defense mechanism. However, if this activation is not properly regulated, excessive inflammation induced by overactivated NLRP3 inflammasome can be detrimental to the host, causing tissue damage and organ dysfunction, eventually causing several diseases. Previous studies have suggested that mitochondrial damage may be a cause of NLRP3 inflammasome activation and autophagy, which is a conserved self-degradation process that negatively regulates NLRP3 inflammasome activation. Recently, mitochondria-selective autophagy, termed mitophagy, has emerged as a central player for maintaining mitochondrial homeostasis through the elimination of damaged mitochondria, leading to the prevention of hyperinflammation triggered by NLRP3 inflammasome activation. In this review, we will first focus on the molecular mechanisms of NLRP3 inflammasome activation and NLRP3 inflammasome-related diseases. We will then discuss autophagy, especially mitophagy, as a negative regulator of NLPP3 inflammasome activation by examining recent advances in research.

• The Journal of the Korea Contents Association
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• v.10 no.3
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• pp.463-471
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• 2010

The purpose of this study is to articulate learning model based on achievement level in blended learning environment. In order to investigate the variables and mechanisms in the blended learning environment, we started by attempt to develop two questionnaires using the components of web-based instruction and self-regulated learning. And its results were implemented to represent the topology and directed merging path within components. 154 students at a high school were required to take each web course respectively for two weeks. And questionnaires data, achievement levels data were collected and analyzed. Various statistical analysis methods such as correlation analysis, classical multidimensional scaling, multiple regression analysis, were applied to the data. As an result, the topology and directed path within factors of blended learning process were derived and revised as a final model.

• Archives of design research
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• v.11 no.1
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• pp.99-108
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• 1998

The purpose of this study was to exanune the effects of learning training program on university students' creativity. In order to accomplish this purpJse of the study effectively, the following research hypotheses were posited: (Hypothesis 1) The treJltment group trained with the learning program will perform better in technic.al class. (Hypothesis 2) The treatment group trained with the learning program will show the higher degree of progress in diagram creativity than the pre-treatment group. The result of the study were summarized as follows: First, regarding the effects of training, there appeared a significant difference between the groups of post-treatment class and pre-treatment class in the use of learning strategies. Second. there appeared a significant difference between the group of post-treatment class and pre-treatment class in diagranl creativity.

• The Journal of the Korea Contents Association
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• v.10 no.12
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• pp.477-491
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• 2010

This paper aimed to understand current trends in online lectures for Korean SAT based on students' academic performances through a qualitative interview approach. In results, the highest academic performance group showed a good deal of interest and usage in online lectures. This group participants preferred private online lectures to public ones. However, the lowest academic group liked to use public online lectures. The middle academic groups who lived in an expensive area spent a lot of money for tutoring or attending private institutes rather than online lectures. Suggestions are: self-regulated learning is needed, public onilne lectures should have improved contents, and lastly, these online lectures are required to be connected with regular school curriculum.

• Journal of Korean Elementary Science Education
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• v.33 no.3
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• pp.524-535
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• 2014

The purpose of this study was to develop the creative hands-on activities using EM (effective microorganisms) that can enhance the environmental literacy of learners, and to examine the effect of its application. The program was composed of 10 sessions, including biological knowledge and ecosystem status of microorganisms, practical activities that stimulate the environmental behavior and emotion of elementary school students, and career design related to their aptitude and occupation in future. This program can also be connected to the domains of creative hands-on activities, that is, career activities, club activities, self-regulated activities and voluntary service activities. In this study, two classes of 3th grades of elementary school in Seoul were selected and divided into two groups. The experimental group to undergo the program of creative hands-on activities using EM showed higher environmental literacy than the control group. In the concrete, it is proven that this program contributed to the improvement of learners' environmental emotion, skill, and behavior. When interviewed with experimental group, we found that sustained EM hands-on activities were conducted in collaboration with their families, and they became more aware of the utilities of EM and could participate in the activities more interestingly. In conclusion, the creative hands-on activities program was very effective and helped elementary students to change their environmental literacy in positive ways.

• Journal of Technologic Dentistry
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• v.36 no.4
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• pp.267-275
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• 2014

Purpose: The purpose of this study is to analyze denture satisfaction by burdened cost types. Methods: All 588 subjects in Gyeongsangnam-do, Korea was surveyed randomly. The study was conducted for about 24 days from March 28th to April 20th, 2014. The objects who participated in the survey were offered self-report questionnaires for this study. Results: Satisfaction with Half Price of the National Health Insurance Support Denture patients appears the highest point of $2.98{\pm}0.22$, and The Governor Pledge Free Denture appears $2.90{\pm}0.17$ the lowest. Also Pay Denture appears $2.96{\pm}0.21$. Provincial authority regulated medical carelessness inefficiently and at all during the procedure, without having to pay the cost of individual. also provincial authority support low budget. This is the result from the lowest satisfaction of The Governor Pledge Free Denture patient. Conclusion: According to the survey results, The Governor Pledge Free Denture and The Total Pay Denture's satisfaction are higher than The National Health Insurance Support Denture. and The National Health Insurance Support Denture are more uncomfortable than pay denture to use.

• Journal of The Korean Association of Information Education
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• v.22 no.1
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• pp.159-167
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• 2018

In this study, we have developed an online learning community site using Humhub social network software and promote social constructive learning through the questions and answers in subject specific learning groups. By accumulating learning contents which consist of questions and answers about specific topics, learners can acquire knowledge by searching relevant topics and questions and can create and reconstruct knowledge as well as consuming knowledge by participating in self-regulated learning community. We have developed a mathematical editor feature which enables users to enter mathematical expression such as equations and greek characters. Online learning community sites can be used for inquiry based information education.