• Title/Summary/Keyword: Safety assesment

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Comparison or Antioxidative Activities or Crotaiarta sessiflora L. Extracts from Leaves, Seed, Stem and Root (활나물 부위별 추출물의 항산화 활성 비교)

  • Woo, NaRiYah;Kim, Tae-Su;Park, Hee-Woon;Park, Chun-Geon;Seong, Ha-Jeong;Ko, Sang-Heom;Jung, Jin-Woo;Kang, Myung-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.9
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    • pp.1297-1301
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    • 2005
  • This study was carried to develop the new functional food material by exploring natural antioxidant substances of Crotalaria sessiflora L. We compared antioxidative activity of potential antioxidant substances extracted from Crotalaria sessiflora L. The order of extract yield of Crotalaria sessiflora L. were stem > loaves > seed > root. Antioxidative activities of Crotalaria sessiflora L. were measured by total polyphenol contents EDA (electron donating activity), SOD (superoxide dismutase) -like activity, hydroxyl radical scavenging ability and hydrogen peroxide radical scavenging ability. Total polyphenol acid content was much higher in leaves Ex than other extracts. And leaves Ex showed the most excellent antioxidative activity ($86.27\%$) in terms of SOD-like activity. The EDA was ordered loaves Ex > stem Ex > seed Ex > root Ex. Hydroxy radical scavenging ability was the most effective in loaves Ex, and hydorogen Peroxide radical scavenging ability was the highest in seed Ex. Therefore we could be certain that leaves Ex was the most effective in antioxidative activity from Crotalaria sessiflora L.

Proficiency Testing for the Gas-chromatographic Analysis of Procymidone, Chlorpyrifos and Metolachlor Residues in Soil (가스크로마토그래피를 이용한 토양 중 프로사이미돈과 클로르피리포스, 메톨라클로르의 잔류분석 숙련도시험)

  • Kim, Chan-Sub;Son, Kyeong-Ae;Gil, Geun-Hwan;Kim, Jin-Bae;Hong, Su-Myeong;Kwon, Hye-Young
    • The Korean Journal of Pesticide Science
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    • v.17 no.2
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    • pp.94-106
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    • 2013
  • The proficiency testing for the residue laboratories of pesticide registration was conducted in order to improve the reliability and the ability for pesticide residue analysis. On October 2011 the testing was carried out using the soil collected and kept as the moistened state for five years, which is expected to very low residue levels of pesticides. The soil was fortified with chlorpyrifos, metolachlor and procymidone in a manner similar to prepare soil sample for indoor soil degradation test, and then sub-samples were prepared for the distribution to participants. Some of them were randomly selected for confirm of homogeneity and to ensure the stability of samples at room temperature. Samples were consisted of two soil treated as different levels, one of which was used to the assesment and another used to confirm. In addition, provide three standard solutions, respectively concentration of 10 mg/L, and untreated soil. Forty seven institutions submitted results. The medians of results were used as the assigned values for pesticide residues. Fitness for purpose standard deviation of proficiency test was calculated by applying 20% RSD as the coefficient of variation allowed in the soil residue test. Z-score was applied for evaluation of individual pesticides, and the average of the absolute value of the Z-score for the overall assessment of pesticides. Laboratories evaluated the absolute value of the Z-score less than 2 to fit the case of chlorpyrifos and procymidone were 44, metolachlor 40.

Effective Customer Risk Management at the Nuclear Medicine Department: Risk Managemont MOT Development Application and Producing Public Relations Film (핵의학과 내에서의 효과적인 고객위험관리: 위험관리 응대 MOT 개발적용 및 홍보동영상 제작)

  • Ham, Jong-Hum;Hwang, Jae-Bong;Kim, Joon-Ho;Lee, Gui-Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.110-122
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    • 2009
  • Purpose: Nowadays, A medical institution assesment could get more interest about a quality of medical services from many hospitals that developed the active activities for improving medical services. Also, there is an other additional issue which is the patients risk management. Uijeongbu ST. Mary's hospital Nuclear Medicine department has been changed many work process after PET-CT introduction and renovation of its place since 2008. Therefore, modified structure and the way of existing work process have contained risk factors. The purpose of this study would be the appropriate risk management process while imaging examination process, the removal risk factors and improved activities through the analysis risk factors. Materials and Methods: Nuclear Medicine department new process should analysis through many-sided, Firstly, make and trained risk management manual after then apply an actual work. Result analysis showed the number of risk accident occurrence that comparing the last year and after the improved activities. Secondly, producing risk management public relations film has been showed an applicable patient after then the customer service measurement checked for a hundred patient by questionnaire. Lastly, Risk factors were eliminated through the facilities participation improving activities which could change for the better risk factors. Results: The number of safety accident occurrence(medication error, fall and collision) were checked as zero after the improving activities both PET-CT and gamma camera examination. The results of questionnaire showed as follows; 74% marked as understanding of the test process and 81% checked "satisfaction" after the public relations film showing. The question "Did you consider about the risk factors?", both PET-CT and gamma camera checked as 94% and 89% respectively. Customer risk management could be accomplished effectively through the improving activities at the nuclear medicine department. Conclusions: The study would be an opportunity that spread risk factors were systematically showed and analyzied. Also, It showed the possibility of the minimized safety accident and its feedback, if application of the response manuel that could be a standard of radiology technician's work method to react safety accident. It was the more effective that visual material could be easy to approach as a methodology of risk factors. As far as I have concerned that It could help the safety and convenience through continuous and detailed activities that offer to patients.

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Safety Assesment of Pesticides Treated on Garlic to Control Black Rot during the Storage (마늘 저장 중 부패병 방제를 위하여 처리한 농약의 경시적 농약 잔류량 평가)

  • You, Oh-Jong;Jin, Yong-Duk;Hwang, Se-Gu;Lee, Yong-Hoon;Ihm, Yang-Bin;Kim, Jin-Bae;Kwon, Oh-Kyung;Kyung, Kee-Sung;Kim, Jang-Eok
    • The Korean Journal of Pesticide Science
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    • v.13 no.3
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    • pp.148-158
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    • 2009
  • We tested and selected some agrochemicals reducing the occurrence of major pests and diseases during garlic storage. Tebuconazole, diphenylamine and prochloraz as fungicides and dimethate as a insecticide were sprayed or drenched before harvest. And the harvested garlic was dipped in each of the agrochemicals. The residues of pesticides in garlic bulbs treated were analyzed every month from harvesting time for 6 months. In case of Danyang garlic, which was treated with pesticides before and after harvesting, the residues of diphenylamine, tebuconazole, prochloraz, and dimethoate ranged from 0.008 to 0.28, from 0.03 to 0.32, from 0.02 to 0.12, and from 0.02 to 0.25 mg/kg, respectively. In case of Uiseong garlic, the residues of diphenylamine, tebuconazole, prochloraz and dimethoate ranged from 0.008 to 0.09, from 0.08 to 0.45, from 0.02 to 0.57, and from 0.04 to 0.38 mg/kg, respectively. And, in case of Namdo garlic, the residues of diphenylamine, tebuconazole, prochloraz, and dimethoate ranged from 0.008 to 0.52, from 0.07 to 1.67, from 0.02 to 0.17, and from 0.03 to 0.73 mg/kg, respectively. Some of the garlic samples treated with tebuconazole exceeded its maximum residue limits (MRLs) of 0.1 mg/kg set by Korea Food Drug Administration (KFDA), but dimethoate was detected below its MRL of 1.0 mg/kg. In case of diphenylamine and prochloraz, their MRLs for garlic were not set. Adapting their MRLs, 5.0 mg/kg of diphenylamine for apple and pear and 0.5 mg/kg of prochloraz for strawberry and grape, residue levels of diphenylamine and procloraz were below than their MRLs, with the exception of samples two times treated with procloraz in Namdo garlic. These results indicate that dimethoate can be used as an agrochemical to control the postharvest disease in garlic in only MRL aspect.

The Study on Evaluating Value for Developing Traditional Agriculture Technology (고농서에 나타난 전통농업기술의 개발가치 평가)

  • Rhee, Sang Young;Kim, Mi Heui;Choi, Jai Ung
    • Journal of Agricultural Extension & Community Development
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    • v.21 no.3
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    • pp.243-269
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    • 2014
  • Traditional agriculture technology is absolutely valuable not only to preserve biological diversity but construct an eco-friendly agricultural system. As the awareness of food safety has been growing, traditional technologies in the past agriculture literatures have obtained more attention sine chemical or synthesized fertilizer and agricultural pesticide were not used in these traditional agriculture ways. This study aims to evaluate development values on six kinds of agriculture literatures published before initial 1970s using Delphi technique and Correspondence analysis. The domains of assesment are include livestock sanitation, breeding management, feeding program and an extra part which 261 traditional agriculture technologies were first extracted from. From these technologies, livestock experts deducted 228 items and selected items more than 3.0 from all three areas including usefulness, scientific characteristic and economical efficiency utilizing Delphi technique.: 35 items from usefulness, 31 items from scientific characteristic, and 18 items from economical efficiency. The 23 technology items were finalized after adding five modern feasibility items recommended by experts to 18 items gaining more than 3.0 in at least three areas. The agriculture technologies were categorized into four areas where were analyzed using Correspondence analysis. The results revealed that 'sustainable farming technology', 'scientific character verification', ' modernized technology development', and 'intellectual property right' were placed closely one another except 'economy efficiency'. The result implicated that scientific verification and economy efficiency should be considered in order to sustain traditional agriculture technology into a modernized way and to protect intellectual property right of these technologies.

Antioxidant Effects of Crotalaria sessiliflora L. Leaf Extracts Fractionated from Each Solvent (활나물 잎 추출물의 분획별 항산화 활성)

  • Kim, Tae-Su;Ko, Sang-Beom;Park, Chun-Geon;Seong, Ha-Jeong;Kang, Myung-Hwa
    • Journal of the East Asian Society of Dietary Life
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    • v.19 no.2
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    • pp.180-186
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    • 2009
  • In this study, Crotalaria sessiliflora L., leaf was extracted with a solvent mixture of $CH_2Cl_2$ and $CH_2OH$ (3:1). In order to draw or separate effective components from the leaf extract with high activity, a 1:1 solvent mixture of water and butanol was used after removal of the sugar and fat from the extract. From the decompressed and concentrated butanol layer, 10 small fractions (Fr1, Fr2, Fr3, Fr4, Fr5, Fr6, Fr7, Fr8, Fr9, and Fr10) were obtained using a chromatography column filled with sephadex LH-20. The activity of each fraction was measured by the same method as that used to measure the antioxidant effect of each part(p<0.05). The Fr1, Fr4, and Fr6 fractions showed the highest activity levels(p<0.05). The vital unknown material that vitality exists in the strong butanol fractions of F1, F4 and F6 will be isolated and identified. Currently, we are performing for a single compound from an unknown peak by instrumental analysis.

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Development of Extracts of Lycii folium Having High Antioxidant Activity (항산화 활성이 높은 구기엽 추출물 제조)

  • Kim, Tae-Su;Park, Won-Jeong;Ko, Sang-Beom;Kang, Myung-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.10
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    • pp.1318-1322
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    • 2008
  • The aim of this study was to analyze the antioxidant properties of Lycii folium extracts prepared from different solvents. Lycii folium were extracted with water, 80% ethanol (80% EtOH), 80% methanol (80% MeOH) and 100% methanol (100% MeOH) in water bath at $40^{\circ}C$. The antioxidant activity of the extracts was evaluated using DPPH, hydroxyl and hydrogen radical scavenging activities, and SOD-liked activity. Total phenolic acid contents were 1.085 mg/mL in 100% MeOH, 1.382 mg/mL in 80% EtOH, 1.420 mg/mL in 80% MeOH and 1.084 mg/mL in water. DPPH radical scavenging activity of the extracts were 65.60% in 80% EtOH, 56.80% in 80% MeOH, 83.85% in 100% MeOH and 54.65% in water. Hydroxyl radical scavenging activities were 66.65% in 100% MeOH, 73.13% in 80% ethanol, 73.58% in 80% MeOH and 70.73% in water. Hydrogen radical scavenging activity of the extracts prepared from Lycii folium were 11.70% in 100% MeOH, 33.73% in 80% EtOH, 35.40% in 80% M eOH and 23.86% in water. SOD-liked activity of the extracts prepared from Lycii folium was 71.58% in 100% MeOH, 74.29% in 80% EtOH, 88.46% in 80% MeOH and 67.47% in water. Our result showed that Lycii folium extracts prepared from 80% methanol were found to be promising biomaterials with antioxidant effects.

Monitoring of Pesticide Residues and Risk Assessment of Agricultural Products Consumed in South Korea (국내유통농산물 중 잔류농약 모니터링 및 안전성 평가)

  • Kim, Sung-Hun;Choe, Won-Jo;Baik, Yong-Kyoo;Kim, Woo-Seong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.11
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    • pp.1515-1522
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    • 2008
  • Monitoring the pesticide residues in agricultural products is essential to protect consumers, obtain data for risk assessment, and ensure fair trade practices. We developed a multi-residue method for the analysis of 37 pesticides with different physico-chemical properties in agricultural products and analyzed the amount of pesticide residues on about 1,000 samples circulated in South Korea. The samples consisted of 26 different types of agricultural products selected at markets in 14 major cities; cereals (2 species), nuts (1 species) potatoes (1 species), beans (2 species), fruits (3 species), vegetables (16 species), and mushrooms (1 species). In this study, residual pesticides were detected in 23 samples (2.2%) and one sample was detected to be over maximum residue limits (MRLs, 0.1%) for pesticides in foods by the Korea food code. In leafy vegetables such as pepper leaves, radish leaves, cham-na-mul, shin-sun-cho, crown daisy, chwi-na-mul and citrus fruits such as kumquat, 8 kinds of pesticides were detected. Specially, diazinon were detected over MRLs and also, endosulfan, ethoprophos and phenthoate were detected frequently. Based on these results, we investigated the risk assesment from amount of residual pesticide, total %ADI was 1.262%, but the value has not effected on human health.

Influence of heading date difference on gene flow from GM to non-GM rices (GM벼에서 non-GM벼로 유전자 이동에 대한 개화기 차이의 영향 분석)

  • Oh, Sung-Dug;Chang, Ancheol;Kim, Boeun;Sohn, Soo-In;Yun, Doh-Won
    • Journal of the Korean Society of International Agriculture
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    • v.30 no.4
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    • pp.347-356
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    • 2018
  • Genetically modified (GM) crops have been increased continuously over the world and concerns about the potential risks of GM crops have also been increasing. Even though GM crops have not been cultivated commercially in Korea, it should be necessary to develop the safety assesment technology for GM crops. In this study, we investigated the influence of heading date difference on gene flow from GM to non-GM rice. In the experimental plot design, The PAC GM rice was placed in the center as a pollen donor and non-GM rice were placed in eight directions as pollen receivers. Five pollen receiver rice cultivars were Unkawng, Daebo, Saegyejinmi, Nakdong-byeo, and Ilmi which had different flowering times. A total of 266,436, 300,237, 305,223, 273,373, and 290,759 seeds were collected from Unkawng, Daebo, Saegyejinmi, Nakdong, and Ilmi, respectively, which were planted around PAC GM rice. The GM${\times}$non-GM hybrids were detected by repeated spraying of herbicide and PAT immunostrip assay. Finally, the hybrids were confirmed by PCR analysis using PAC gene specific primer. The hybrids were found in Nakdong-byeo which had the same heading date with PAC GM rice. The hybridization rate was 0.0007% at Nakdong-byeo plot. All of GM${\times}$non-GM hybrids were located within 2 m distance from the PAC GM rice zone. The physiological elements including rice heading date were found to be important factors to determine GM?rice out crossing rate with GM rice. Consideration should be taken into for many factors like the physiological elements of field heading date of rice cultivars to set up the safety management guideline for prevention of GM rice gene flow.