• Asian Pacific Journal of Cancer Prevention
• /
• 제15권6호
• /
• pp.2405-2425
• /
• 2014

Radiation exposure leads to several pathophysiological conditions, including oxidative damage, inflammation and fibrosis, thereby affecting the survival of organisms. This review explores the radiation countermeasure properties of fourteen (14) plant extracts or plant-derived compounds against these cellular manifestations. It was aimed at evaluating the possible role of plants or its constituents in radiation countermeasure strategy. All the 14 plant extracts or compounds derived from it and considered in this review have shown some radioprotection in different in vivo, ex-vivo and or in vitro models of radiological injury. However, few have demonstrated advantages over the others. C. majus possessing antioxidant, anti-inflammatory and immunomodulatory effects appears to be promising in radioprotection. Its crude extracts as well as various alkaloids and flavonoids derived from it, have shown to enhance survival rate in irradiated mice. Similarly, curcumin with its antioxidant and the ability to ameliorate late effect of radiation exposure, combined with improvement in survival in experimental animal following irradiation, makes it another probable candidate against radiological injury. Furthermore, the extracts of P. hexandrum and P. kurroa in combine treatment regime, M. piperita, E. officinalis, A. sinensis, nutmeg, genistein and ginsan warrants further studies on their radioprotective potentials. However, one that has received a lot of attention is the dietary flaxseed. The scavenging ability against radiation-induced free radicals, prevention of radiation-induced lipid peroxidation, reduction in radiation cachexia, level of inflammatory cytokines and fibrosis, are some of the remarkable characteristics of flaxseed in animal models of radiation injury. While countering the harmful effects of radiation exposure, it has shown its ability to enhance survival rate in experimental animals. Further, flaxseed has been tested and found to be equally effective when administered before or after irradiation, and against low doses (${\leq}5Gy$) to the whole body or high doses (12-13.5 Gy) to the whole thorax. This is particularly relevant since apart from the possibility of using it in pre-conditioning regime in radiotherapy, it could also be used during nuclear plant leakage/accidents and radiological terrorism, which are not pre-determined scenarios. However, considering the infancy of the field of plant-based radioprotectors, all the above-mentioned plant extracts/plant-derived compounds deserves further stringent study in different models of radiation injury.

• Journal of Technology Innovation
• /
• 제26권4호
• /
• pp.98-121
• /
• 2018

This article analyzes the survival of Korean software firms from 1995 to 2015 by Cox regression model and product-limit method. The results show that survival rates are different for each sector: IT service, package software, game software and internet service. In addition, firm growth and investment in research and development positively affect software firm's survival, while slack resources negatively affect the software firm's survival. The implication of this study is that characteristics of the software industry and technologies should be taken into consideration in survival strategy of software firms and government policy. Previous research on survival analysis has been mainly conducted in the manufacturing industry or at the special circumstance such as the foreign exchange crisis of Korea in the late 1990s. The contribution of this study is that expanding the survival analysis to software firms in Korea which are becoming more important recently.

• Proceedings of the Korean Operations and Management Science Society Conference
• /
• 한국경영과학회 2006년도 추계학술대회
• /
• pp.17-20
• /
• 2006

Inside the global management environment that is going through sudden changes, businesses are concentrating on putting in much hard work to establish the most competitive management strategy for its survival. As a executing tool and following the strategy establishment, BSC is being introduced and used by many businesses and public institutions, but instead of being used as a tool with the proper purpose of executing strategies, in reality, it is mainly being used to measure and evaluate outcomes. Of the several reasons why this is so, one important issue and its fundamental cause is that although BSC had been developed as a strategy executing tool, it is diffcult to understand the degree of execution of strategies because the overall measurement of the KPI includes all the strategic and operational parts. Through case study, this article acts on presenting the methodology of measuring the degree of execution of strategies that apply the BSC and PM frameworks.

• Knowledge Management Research
• /
• 제12권3호
• /
• pp.73-96
• /
• 2011

Recent market saturation makes the local retailers consider an attempt to innovate the market with the retailer's brand. This is the retailers' efforts to expand the market control through the enhancement of private brands. As the competition among manufacturers extends to the competition between manufacturers and retailers, the marketing knowledges of manufacturers need to be diversified to the ones that can be applied to the manufacturers and retailers due to their bilateral competition. This research concentrates on the customer acquisition strategy (attack strategy) and customer retention strategy (defense strategy) in the place of both sides of manufacturers and retailers. Also this research targets to develop the differential marketing strategies for target market's National Brand(NB)/Private Brand(PB) purchase by analyzing individual customer's purchase probability on repurchase and switch-purchase of NB and PB. This study is based on the data of frequently consumed product, tomato ketchup on scanner panel from the ERIM data of University of Chicago, USA. This study compares and analyzes the NB and PB repurchases and switch-purchase of 4 types. The comparisons provide the informations that which factors should be managed for the attack strategy, the defense strategy, and the differential marketing strategies both for manufacturers and retailers. This research is expected to contribute on cumulating the industrial knowledges of retailers' and manufacturers' survival strategy, expecially focusing on the effect of marketing factors and consumer-characteristic factors.

• Archives of design research
• /
• 제17권4호
• /
• pp.385-396
• /
• 2004

The progresses in the Korean design promotion strategy since the 1950s have been studied. Korean design strategy was somewhat limited in the imitator who copied advanced nations strategies at the beginning. Their strategies changed to adopter and/or modifier in conjunction with the Korean economic development. It has pursued pioneer strategies since 2000. This study has identified the changing environment of design, the nature of design promotion strategy, the historical background and current states of world design promotion. Finally, it has suggested four challenges for transforming Korea into the world class design nation: Formulation of law for cultivating the design industry; enhancing the self-survival power of Korea Institute of Design Promotion(KIDP), the establishment of the Korea Design Promotion Foundation, upgrading the Korea Federation of Design Associations(KFDA).

• Strategy21
• /
• 통권39호
• /
• pp.82-113
• /
• 2016

This paper analyzes the contents and the effects of the UNSC 2270, and its implications to South Korea's defense strategy and navy. The UN Security Council passed strong sanctions against North Korea which punish North Korea's 4^th nuclear test. The sanctions compared to the previous ones require international society to take practical actions such as comprehensive trade bans as well as diplomatic isolation which will put significant pains on North Korea. Especially, these measures would greatly hamper economic development policy of Kim Joung-un regime. Because Kim Jung-un regime has inherent legitimacy problems which stems from the third family succession of the power, economic difficulties may play an important cause on the regime instability in the long term. In fact, the United States sees this possibility as an option to coerce North Korea in which North Korea choose denuclearization for its regime survival. Nevertheless, the prospects of the UN sanctions are not so optimistic. Considering North Korea's willingness for nuclear development and its level of nuclear technology, North Korea will try to play a gambit with the US and South Korea by exploiting its strategic advantages. North Korea's response will have three following strategies. First, it would actively pursue political and economic survival strategy by using China's support for the regime, strengthening its power grip in the name of countering US hostile policy, and enhancing peace propaganda. Second, North Korea will accelerate efforts to position its status as a nuclear de facto state. For this purpose, it could create nuclear crisis on the peninsula. Third, it would exploit local provocations as an exit strategy to get over the current situation. In order to counter North Korea's actions and punish North Korea's behavior strongly, South Korea needs following strategies and efforts. It should first make all the efforts to implement the UN sanctions. Strong and practical nuclear deterrence strategy and capability with the U.S. should be developed. Effective strategy and capabilities for the prevention and deterrence of North Korea's provocation should be prepared. For this purpose, North Korea's provocation strategy should be thoroughly reviewed. Active international cooperation is needed to punish and coerce North Korea's behavior. Finally, South Korea should prepare for the possible occurrence of North Korea's contingency and make use of the situation as an opportunity to achieve unification. All these strategies and efforts demand the more active roles and missions of South Korea's navy and thus, nullify North Korea's intention militarily.

• Management & Information Systems Review
• /
• 제18권
• /
• pp.115-132
• /
• 2006

The main findings of this study are summarized as follows; 1) For medium-small size Family Restaurant(FR) in the FR market, nowadays, survival is the key issue. If the medium-small size FR is to survive and continue to grow under this competitive environment, it must pursued the efficiency of management with niche marketing strategy. 2) This study is to describe the niche marketing strategy for medium-small size FR. Strategic niche marketing must be based on the target market, market positioning and strategic marketing mix. 3) Medium-small size FR needs to develop the marketing mix factors for the niche marketing strategy. It needs to make customers understand what the FR differs from current and potential competitors. Essentially the medium-small size FR must take a competitive advantage. Hence it will appeal to a substantial number of the segments customers. 4) In using niche marketing strategy, a medium-small size FR must establish the objectives, select the tools, develop the decisions on product differentiation, market segmentation and positioning under various strategic niche marketing factors 5) By carrying out the niche marketing strategy on the target market, customer's desire can be further fulfilled. When management efficiency is improved, we can better cope with changing environment.

• International Journal of Quality Innovation
• /
• 제7권2호
• /
• pp.157-172
• /
• 2006

Due to the advancement of technology and rapidly changing environment of the market, the life cycle of high-tech products is becoming shorter. The enterprise must constantly innovate and select correct development strategy of new product in order to respond to customers' demands for upgrading operational performance of industry. Development of new product is the critical activity for enterprise's survival and growth. This research focuses on the effects of Taiwan high-tech companies' introduction of innovative activity and development strategy of new product on development performance of new product for analysis and exploration. The result findings reveal that: (1) High execution degree of innovative activity has positive effect on the implementation of development strategy of new product; (2) The companies with better implementation of development strategy of new product reveal better development performance; (3) The companies with higher degree of execution of innovative activity and better execution of development strategy of new product reveal better development performance of new product.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제17권9호
• /
• pp.2419-2435
• /
• 2023

Command and control networks(C2N) exhibit evident multi-network interdependencies owing to their complex hierarchical associations, interleaved communication links, and dynamic network changes. However, the existing command and control networks do not consider the effects of dependent nodes on the load distribution. Thus, we proposed a command and control networks load allocation strategy based on interdependence strength. First, a new measure of interdependence strength was proposed based on the edge betweenness, which was followed by proposing the inter-layer load allocation strategy based on the interdependence strength. Eventually, the simulation experiments of the aforementioned strategy were designed to analyze the network invulnerability with different initial load capacity parameters, allocation model parameters, and allocation strategies. The simulation indicates that the strategy proposed in this study improved the node survival rate of the interdependent command and control networks model and successfully prevented cascade failures.

• International Journal of Costume and Fashion
• /
• 제5권1호
• /
• pp.90-95
• /
• 2005

The purpose of this study is to analyze Korea's fashion industry and find out the ways to settle recent crisis of the field. This study considered the environments of domestic or foreign fashion industry, then tried to find efforts to become one of the world's top companies and products.