• Nuclear Engineering and Technology
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• v.19 no.4
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• pp.292-309
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• 1987

A large dry PWR containment response analysis for postulated severe accidents was performed as part of the Zion Risk Rebaselining study for input to the U.S. NRC's "Reactor Risk Reference Document," NUREG-1150. The Methodologies used in the present work were developed as part of the Severe Accident Risk Reduction Program (SARRP) at Sandia National Laboratory specifically for the Surry Plant, but they were extrapolated to Zion. Major steps of the quantification of risk from a nuclear power plant are first outlined. Then, the methodologies of containment response analysis for severe accidents used for Zion are described in detail: major features of the containment event tree (CET) analysis codes and CET quantification procedures are summarized. In addition, plant specific features important to containment response analysis are presented along with the containment loading and performance issues included in the present uncertainty analysis. Finally, a brief summary of the results of deterministic and statistical containment event tree analysis is presented to provide a perspective on the large dry PWR containment response for postulated severe accidents.accidents.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.2
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• pp.38-45
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• 2012

If an infant with congenital hearing loss is diagnosed in good time and get proper treatment as soon as possible, treatment effect could be maximized and the social costs could be considerably reduced. For these reasons, the medical equipment to screen hearing impairment objectively is needed. The ABR(auditory brainstem response) is typical diagnostic tools for this purpose but there are drawbacks in sense that it does not have frequency specificity and shows hearing information of usually high frequency band. The ASSR(auditory steady-state response) is excellent in frequency specificity, but the rate of wrong diagnosis is slightly high. In this study, we proposed the system which can measure both the ABR and the ASSR, and can show the objective and quantitative indices(Fsp and F-test). It was designed to allow various tests without hardware modification by minimizing hardware components and by increasing software roles. The objective assessment of the developed system was evaluated by experiments with 10 normal persons.

• Clean Technology
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• v.23 no.4
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• pp.413-420
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• 2017

The batch experiments and response surface methodology (RSM) have been applied to the investigation of the Cs adsorption with zeolite X synthesized using coal fly ash generated from the thermal power plant. Regression equation formulated for Cs adsorption was represented as a function of response variables. The model was highly relevant because the decision coefficient ($r^2$) was 0.9630. It was confirmed from the statistical results that the removal efficiency of Cs was affected by the order of experimental factors as pH > Cs concentration > temperature. The adsorption kinetics were more accurately represented by a pseudo second-order model. The maximum adsorption capacity calculated from the Langmuir isotherm model was $151.52mg\;g^{-1}$ at 293 K. Also, according to the thermodynamic parameters calculated from Vant Hoff equation, it could be confirmed that the adsorption reaction was an endothermic reaction and a spontaneous process.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.20 no.2
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• pp.96-104
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• 1984

This paper is on the prediction and response of the ship hull girder due to slamming of foreward flat bottom plate. The response with respect to foreward flat bottom is divided two kinds by estimating method. One is the estimation of impact forces by slamming, Another is the response of hull girder due to impact forces, that is, displacement, velocity, acceleration, etc. must calculate the values for considered ship hull girder. In this paper, therefore, was estimated only impact forces along ship ordinate of foreward. The analysis of data for estimation followed mainly papers of Ochi. These estimated data shall contribute for ship gull construction for basic optimum design. In particular, the estimated impact forces shall be given for the response of ship gull girder on the foreward flat bottom plate with characteristics of external forces.

• Journal of the Korean Geotechnical Society
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• v.36 no.10
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• pp.41-56
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• 2020

For the rapid and accurate warning, the system requires not only the sufficient number of seismometers but also the appropriate detection technique of sensor data. Instead of installing new seismometers, on-board accelerometers of the train could be utilized as alternatives. However, the data from on-board accelerometers includes train vibrations and the response of embankment site by earthquake, which are different from earthquakes measured from the seismometer. This study suggests signal analysis technique to detect earthquake from the on-board accelerometer data. The virtual on-board accelerometer data including the response of embankment site, obtained from site response analysis method, has been constructed. The constructed data has been analyzed using short time Fourier transform (STFT) and wavelet transform (WT). STFT method provides better performance to detect long-period earthquake whereas WT method is more available to detect short-period earthquake.

• Journal of Aquaculture
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• v.19 no.2
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• pp.90-94
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• 2006

The effects of formalin on mixed function oxygenase (MFO) system and stress-response were investigated in olive flounder (Paralichthys olivaceus). Olive flounder was exposed to formalin at the concentration of 300 ppm for 1, 2, 4 and 16 h. Levels of stress-response enzymes together with total protein, glucose and osmolality were quantitatively determined in blood, and the activities of phase I (cytochrome P450, ethoxyresorufin deethylase) and phase II (glutathione S-transferase) hepatic enzymes were also determined. Since the formalin-exposure for 16 h resulted no significant changes in aspartate aminotransferase and alanine aminotransferase, specific enzymes for liver damage, it was thought that it did not cause hepatic tissue damage at the concentration of 300 ppm. However, hepatic MFO system was induced at 1 to 4 h, and stress response was induced after 16 h of exposure. Moreover, it is considered that the depression of MFO activity after 16 h of exposure may not be adaptation to formalin, but toxic response. These results suggest that low concentration of formalin does not cause hepatic tissue damage of fish, but could induce MFO and stress response.

• Journal of Microbiology and Biotechnology
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• v.17 no.4
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• pp.644-649
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• 2007

Response surface model was developed for predicting the growth rates of Salmonella enterica sv. Typhimurium in tryptic soy broth (TSB) medium as a function of combined effects of temperature, pH, and NaCl. The TSB containing six different concentrations of NaCl (0, 2, 4, 6, 8, and 10%) was adjusted to an initial of six different pH levels (pH 4, 5, 6, 7, 8, 9, and 10) and incubated at 10 or $20^{\circ}C$. In all experimental variables, the primary growth curves were well $(r^2=0.900\;to\;0.996)$ fitted to a Gompertz equation to obtain growth rates. The secondary response surface model for natural logarithm transformations of growth rates as a function of combined effects of temperature, pH, and NaCl was obtained by SAS's general linear analysis. The predicted growth rates of the S. Typhimurium were generally decreased by basic (9, 10) or acidic (5, 6) pH levels or increase of NaCl concentrations (0-8%). Response surface model was identified as an appropriate secondary model for growth rates on the basis of coefficient determination $(r^2=0.960)$, mean square error (MSE=0.022), bias factor $(B_f=1.023)$, and accuracy factor $(A_f=1.164)$. Therefore, the developed secondary model proved reliable predictions of the combined effect of temperature, NaCl, and pH on growth rates for S. Typhimurium in TSB medium.

• Toxicological Research
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• v.8 no.2
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• pp.191-203
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• 1992

The immunosuppressive effects of safrole were studied in female BALB/c mouse. Mice were given 100,200and 400mg safrole/kg daily for 14days and evaluated on day 15. The day 4 immunogloblin-M antibody response to T-dependent antigen, sheep red blood cells (SRBC) was inhibited dose-dependently in all doses studied. In vitro antibody response to polyclonal antigen, lipopolysaccharide (LPS) by spleen cell suspensions from safrole-treated mice were also significantly inhibited. When safrole was treated for 14days to mice, and mitogen-induced proliferation of splenocytes were assayed on day 15, there were significant suppression of responses to B-cell mitogen, LPS and T-cell mitogen concanavalin A(Con A) at a dose of 400mg safrole/kg. Direct addition of safrole on the splenocyte culture also produced a dose dependent suppression on in vitro antibody response to LPS, and mitogen-induced lymphoproliferatin at doses of 100,200,400 and 800${\mu}M$ safrole. The role of metabolic activation in safrole-induced suppression of in vitro antibody response was studied using splenocyte-hepatocyte coculture system. The suppression of in vitro antibody respose to LPS by safrole was not altered when safrole were incubated in the splenocyte-hepatocyte system for 4hr as compared with direct addition of safrole in splenocytes culture. Neither the addition of salicylamide, sulfotransferase inhibitor, nor the addation of inorganic sulfate, sulfation cofactor to the splenocyte-hepatocyte coculture, altered the suppression of antibody response by safrole. These results suggest that the immunosuppression by safrole may not by produced by the reactive metabolites which are mediated in carcinogenesis of safrole.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.52 no.4
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• pp.339-346
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• 2016

The aim of this research was to the experimental data using statistical and spectral analyzing method to get the motion reponses of a stern trawler in operation states such as drifting, sailing and trawling according to the wave height. In drifting, the significant and the maximum valuer of roll in beam sea increased according to the wave height, but those of pitch decreased. The response and the period of peak of roll in beam sea were increased, but those of pitch decreased. In navigation, the significant and maximum values of roll increased remarkably according to the wave height, but those of pitch changed a little. The response of roll was highest in quartering sea, beam sea and then following sea, but those of pitch was highest in bow sea, head sea and then beam sea in the order of all wave heights. The period of peak of roll due to the wave height and the wave direction changed from 3.8 to 9.9 seconds, and those of pitch changed from 3.3 to 10.4 seconds. In trawling, the significant and maximum values of roll increased a little according to the wave height, but those of pitch increased significantly. The response of roll was highest in beam sea, bow sea and then quartering sea, but those of pitch was highest in head sea, following sea, and then beam sea in the order. The period of peak of roll due to the wave height and the direction changed from 6.6 to 10.9 seconds, and those of pitch changed from 6.7 to 11.2 seconds.

• Food Science and Biotechnology
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• v.16 no.4
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• pp.557-564
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• 2007

We prepared caviar analogs encapsulated by calcium-alginate gel membranes as a means to replace higher priced natural caviars. Processing the caviar analogs (beluga type) was optimized by response surface methodology with central composite design. Concentrations of sodium alginate ($X_1$) and $CaCl_2\;(X_2)$ were chosen as the independent variables. In order to compare characteristics of the caviar analogs with the natural caviar, sphericity ($Y_1$), diameter ($Y_2$), membrane thickness ($Y_3$), rupture strength ($Y_4$), rupturing deformation ($Y_5$), and sensory score ($Y_6$) were used as the dependent variables. The sphericity of the caviar analogs showed a similar value to that of natural caviar (over 94%) in the range of independent variables. Generally, the $CaCl_2$ concentration ($X_2$) affected all dependent variables to a greater extent than the sodium alginate concentration ($X_l$), For the multiple response optimization of the 5 dependent variables ($Y_1,\;Y_2,\;Y_4,\;Y_5$, and $Y_6$), the desirability function was defined as the following conditions: target values ($Y_1\;=\;100%,\;Y_2\;=\;3.0\;mm,\;Y_4\;=\;1,470\;g,\;Y_5\;=\;1.1\;mm,\;and\;Y_6\;=\;10\;points$). Membrane thickness ($Y_3$) was eliminated from the dependent variables for multiple response optimization because it could not be measured with an image analyzer. The values of the independent variables as evaluated by multiple response optimization were $X_1\;=\;-0.093$ (78%) and $X_2\;=\;-0.322$ (1.07%), respectively.