• Title/Summary/Keyword: Resistance and Induction factors

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Determinants of Plant Growth-promoting Ochrobactrum lupini KUDC1013 Involved in Induction of Systemic Resistance against Pectobacterium carotovorum subsp. carotovorum in Tobacco Leaves

  • Sumayo, Marilyn;Hahm, Mi-Seon;Ghim, Sa-Youl
    • The Plant Pathology Journal
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    • v.29 no.2
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    • pp.174-181
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    • 2013
  • The plant growth-promoting rhizobacterium Ochrobactrum lupini KUDC1013 elicited induced systemic resistance (ISR) in tobacco against soft rot disease caused by Pectobacterium carotovorum subsp. carotovorum. We investigated of its factors involved in ISR elicitation. To characterize the ISR determinants, KUDC1013 cell suspension, heat-treated cells, supernatant from a culture medium, crude bacterial lipopolysaccharide (LPS) and flagella were tested for their ISR activities. Both LPS and flagella from KUDC1013 were effective in ISR elicitation. Crude cell free supernatant elicited ISR and factors with the highest ISR activity were retained in the n-butanol fraction. Analysis of the ISR-active fraction revealed the metabolites, phenylacetic acid (PAA), 1-hexadecene and linoleic acid (LA), as elicitors of ISR. Treatment of tobacco with these compounds significantly decreased the soft rot disease symptoms. This is the first report on the ISR determinants by plant growth-promoting rhizobacteria (PGPR) KUDC1013 and identifying PAA, 1-hexadecene and LA as ISR-related compounds. This study shows that KUDC1013 has a great potential as biological control agent because of its multiple factors involved in induction of systemic resistance against phytopathogens.

A Study on the 2nd Excitation Method for CVCF Generation of Doubly-fed Induction Generator (II) (권선형 유도발전기 CVCF를 위한 2차 여자제어법에 관한 연구 (II))

  • Ahn, Jin-Woo;Hwang, Young-Moon
    • Proceedings of the KIEE Conference
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    • 1990.11a
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    • pp.45-48
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    • 1990
  • This paper deals with the control strategy for constant voltage, constant frequency (CVCF) generation of doubly-fed Induction generator. As induction machine is a nonlinear and multivariable machine, so, the influential factors for CVCF generation of induction generator are the magnitude of output voltage, load current and its power factor, slip of the machine, etc. To get appropriate control scheme and to research the effect of its parameters, the control equation of induction machine is derived and tested. The derived condition is very useful for the CVCF control of the machine and for determing the characteristics of the system. The simulation results show that magnetizing reactance and rotor resistance is a very important parameter in this control system.

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Critical Success Factors for the Induction of ERP System (ERP시스템 도입을 위한 주 성공 요인)

  • Kim, Sung-Je;Cho, Jai-Rip
    • Proceedings of the Safety Management and Science Conference
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    • 2008.11a
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    • pp.167-176
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    • 2008
  • The recent dramatic growth of ERP has changed the way organizations conduct their businesses, and resulted in significant tangible and intangible benefits being realized by participating firms. Despite these various benefits, firms still have problems in implementing and diffusing ERP due to some reasons, such as resistance to the change. This study primarily aims at identifying what factors are significantly affecting the diffusion of ERP system and finding out how these identified factors can be effectively managed.

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The effect of self-objectification through the user's postural habit analysis on the practice of correct posture: App service proposal through EMG sensors and wearable devices (사용자의 자세 습관 분석을 통한 자기 객관화가 바른 자세 실천에 미치는 영향: 근전도센서 및 웨어러블 기기를 통한 앱 서비스 제안)

  • Ye-eun Ko;Ye-jun Kim;Seon Kim;Jae-sun Yi
    • Industry Promotion Research
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    • v.8 no.1
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    • pp.11-22
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    • 2023
  • This study proposes service content that helps people stay in the right posture in their daily lives to manage the pain of musculoskeletal diseases. Resistance factors and induction factors were analyzed through a survey of 143 people and Ethnography. Based on this, we propose an app service that helps practice the right posture by using EMG sensors and wearable devices. This study is meaningful in alleviating musculoskeletal pain and further improving the quality of life by helping to practice and maintain the right posture with service content based on self-objectification through user posture habit analysis.

Sensitization to Doxorubicin by Inhibition of the Nrf2-Antioxidant System (Doxorubicin 매개 세포독성에 대한 Nrf2 경로의 역할)

  • Cho, Jeong-Min;Park, Hyun-M;Kwak, Mi-Kyoung
    • YAKHAK HOEJI
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    • v.52 no.1
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    • pp.67-72
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    • 2008
  • The use of doxorubicin, which is one of the most effective anticancer agents, is often limited by occurrence of acquired resistance in tumor cells. GSH has been shown to be involved in the development of this drug resistance. Transcription factor Nrf2 governs the expression of GSH synthesizing glutamylcysteine ligase (GCL), as well as multiple phase 2 detoxifying enzymes. Here we show that Nrf2 is one of factors determining doxorubicin sensitivity. Nrf2-deficient fibroblasts (murine embryonic fibroblasts, MEF) were more susceptible to doxorubicin mediated cell death than wild-type cells. Doxorubicin treatment elevated levels of Nrf2-regulated genes including NAD(P)H: quinone oxidoreductase (Nqo1) and GCL in wild-type fibroblasts, while no induction was observed in Nrf2-deficient cells. Doxorubicin resistance in human ovarian SK-OV cells was reversed by treatment with L-buthionine-sulfoxamine (BSO), which is depleting intracellular GSH. Finally, transfection of SK-OV cells with Nrf2 siRNA resulted in exacerbated cytotoxicity following doxorubicin treatment compared to scrambled RNA control. These results indicate that the Nrf2 pathway, which plays a protective role in normal cells, can be a potential target to control cancer cell resistance to anticancer agents.

Comparison of Traction Motor design and characteristics for battery driven hybrid tram (무가선 트램용 추진 전동기 설계 및 특성 비교)

  • Ham, Sang-Hwan;Kim, Kwang-Soo;Kim, Mi-Jung;Lee, Hyung-Woo;Lee, Ju
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.1383-1388
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    • 2010
  • The latest generation of tram is low-floor design, various nations in europe and japan have developed battery driven hybrid trams that combine battery and wiring. Battery driven tram system is achieved by contactless power supply system, thus system is needed high efficiency, high power and low weight traction motor for maximization of energy efficiency. Research from abroad is still in induction motor(IM) application, and it is not meet the efficiency and the power per unit volume in IPMSM. In this paper, we design compare IM and IPMSM to apply battery driven tram, and then compare these motors. To design the motor, we estimate the loading condition at first. Loading condition includes rolling resistance, air-drag resistance, and slope resistance. Based on the loading condition by estimation, we determine the power and compute rated voltage and rated current. In this paper, voltage is limited by battery voltage level. As a result, volume about IM is 1.98 times bigger than IPMSM under same condition. Even though IPMSM is bigger than IM in power density per volume, we consider more factors for actual application because there are demagnetization of permanent magnet in IPMSM and so on by external environment conditions.

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Analysis on the Noise Factors of Static Induction Photo-Transistor (SIPT) (1) - The SIPT's Equivalent Circuits for the Analysis on the Noise Factors - (정전유도(靜電誘導) 포토 트랜지스터의 잡음(雜音) 원인(原因) 분석(分析) (1) - 잡음(雜音) 원인(原因) 분석(分析)을 위한 SIPT 등가회로(等價回路) -)

  • Kim, Jong-Hwa
    • Journal of Sensor Science and Technology
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    • v.4 no.4
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    • pp.29-40
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    • 1995
  • In this paper, the noise equivalent cicuits that is necessary to the formulation of D.C. and noise characteristics, residual component and input capacitance so as to analyze on the noise factors of the SIT is proposed. The simplest noise equivalent circuit is the model representing the mechanism of the SIT and the measured values in this model were found as small as the values of the shot-noise. In the source resistance inserted equivalent circuit is conformed that the shot-noise will be reduced by the negative-feedback effect of the source resistance. In oder to analyze the correct noise reduction factor, I proposed the equivalent circuit which the formulas of the source and drain resistance was induced. In the experiment which affirm the equivalent circuits, the influence of the signal source resistance and output load resistance on the residual component is small and the residual component can be expressed by the equivalent input noise resistance. Moreover, the input capacitance is 13.6 pF when the load resistance is $0{\Omega}$ and the capacitance which does not concern with the SIT operation directly, that is, gate wire etc, is 10pF or so.

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Analysis on electrical and thermal characteristics of MI-SS racetrack coil under conduction cooling and external magnetic field

  • Chae, Yoon Seok;Kim, Ji Hyung;Quach, Huu Luong;Lee, Sung Hoon;Kim, Ho Min
    • Progress in Superconductivity and Cryogenics
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    • v.23 no.4
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    • pp.61-69
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    • 2021
  • This paper presents the analysis and experiment results on the electrical and thermal characteristics of metal insulation (MI) REBCO racetrack coil, which was wound with stainless steel (SS) tape between turn-to-turn layers, under rotating magnetic field and conduction cooling system. Although the field windings of superconducting rotating machine are designed to operate on a direct current, they may be subjected to external magnetic field due to the unsynchronized armature windings during electrical or mechanical load fluctuations. The field windings show the voltage and magnetic field fluctuations and the critical current reduction when they are exposed to an external magnetic field. Moreover, the cryogenic cooling conditions are also identified as the factors that affect the electrical and thermal characteristics of the HTS coil because the characteristic resistance changes according to the cryogenic cooling conditions. Therefore, it is necessary to investigate the effect of external magnetic field on the electrical and thermal characteristics of MI-SS racetrack coil for further development reliable HTS field windings of superconducting rotating machine. First, the major components of the experiment test (i.e., HTS racetrack coil construction, armature winding of 75 kW class induction motor, and conduction cooling system) were fabricated and assembled. Then, the MI racetrack coil was performed under liquid nitrogen bath and conduction cooling conditions to estimate the key parameters (i.e., critical current, time constant, and characteristic resistance) for the test coil in the steady state operation. Further, the test coil was charged to the target value under conduction cooling of 35 K then exposed to the rotating magnetic field, which was generated by three phrase armature windings of 75 kW class induction motor, to investigate the electrical and thermal characteristics during the transient state.

Fuzzy-Neuro Controller for Speed of Slip Energy Recovery and Active Power Filter Compensator

  • Tunyasrirut, S.;Ngamwiwit, J.;Furuya, T.;Yamamoto, Y.
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.480-480
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    • 2000
  • In this paper, we proposed a fuzzy-neuro controller to control the speed of wound rotor induction motor with slip energy recovery. The speed is limited at some range of sub-synchronous speed of the rotating magnetic field. Control speed by adjusting resistance value in the rotor circuit that occurs the efficiency of power are reduced, because of the slip energy is lost when it passes through the rotor resistance. The control system is designed to maintain efficiency of motor. Recently, the emergence of artificial neural networks has made it conductive to integrate fuzzy controllers and neural models for the development of fuzzy control systems, Fuzzy-neuro controller has been designed by integrating two neural network models with a basic fuzzy logic controller. Using the back propagation algorithm, the first neural network is trained as a plant emulator and the second neural network is used as a compensator for the basic fuzzy controller to improve its performance on-line. The function of the neural network plant emulator is to provide the correct error signal at the output of the neural fuzzy compensator without the need for any mathematical modeling of the plant. The difficulty of fine-tuning the scale factors and formulating the correct control rules in a basic fuzzy controller may be reduced using the proposed scheme. The scheme is applied to the control speed of a wound rotor induction motor process. The control system is designed to maintain efficiency of motor and compensate power factor of system. That is: the proposed controller gives the controlled system by keeping the speed constant and the good transient response without overshoot can be obtained.

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Simultaneous Inhibition of CXCR4 and VLA-4 Exhibits Combinatorial Effect in Overcoming Stroma-Mediated Chemotherapy Resistance in Mantle Cell Lymphoma Cells

  • Kim, Yu-Ri;Eom, Ki-Seong
    • IMMUNE NETWORK
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    • v.14 no.6
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    • pp.296-306
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    • 2014
  • There is growing evidence that crosstalk between mantle cell lymphoma (MCL) cells and stromal microenvironments, such as bone marrow and secondary lymphoid tissues, promotes tumor progression by enhancing survival and growth as well as drug resistance of MCL cells. Recent advances in the understanding of lymphoma microenvironment have led to the identification of crucial factors involved in the crosstalk and subsequent generation of their targeted agents. In the present study, we evaluated the combinatory effect of blocking antibodies (Ab) targeting CXCR4 and VLA-4, both of which were known to play significant roles in the induction of environment-mediated drug resistance (EMDR) in MCL cell line, Jeko-1. Simultaneous treatment with anti-CXCR4 and anti-VLA-4 Ab not only reduced the migration of Jeko-1 cells into the protective stromal cells, but also enhanced sensitivity of Jeko-1 to a chemotherapeutic agent to a greater degree than with either Ab alone. These combinatorial effects were associated with decreased phosphorylation of ERK1/2, AKT and NF-${\kappa}B$. Importantly, drug resistance could not be overcome once the adhesion of Jeko-1 to the stromal occurred despite the combined use of Abs, suggesting that the efforts to mitigate migration of MCLs should be attempted as much as possible. Our results provide a basis for a future development of therapeutic strategies targeting both CXCR4 and VLA-4, such as Ab combinations or bispecific antibodies, to improve treatment outcomes of MCL with grave prognosis.