• The Plant Pathology Journal
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• 제29권2호
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• pp.174-181
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• 2013

The plant growth-promoting rhizobacterium Ochrobactrum lupini KUDC1013 elicited induced systemic resistance (ISR) in tobacco against soft rot disease caused by Pectobacterium carotovorum subsp. carotovorum. We investigated of its factors involved in ISR elicitation. To characterize the ISR determinants, KUDC1013 cell suspension, heat-treated cells, supernatant from a culture medium, crude bacterial lipopolysaccharide (LPS) and flagella were tested for their ISR activities. Both LPS and flagella from KUDC1013 were effective in ISR elicitation. Crude cell free supernatant elicited ISR and factors with the highest ISR activity were retained in the n-butanol fraction. Analysis of the ISR-active fraction revealed the metabolites, phenylacetic acid (PAA), 1-hexadecene and linoleic acid (LA), as elicitors of ISR. Treatment of tobacco with these compounds significantly decreased the soft rot disease symptoms. This is the first report on the ISR determinants by plant growth-promoting rhizobacteria (PGPR) KUDC1013 and identifying PAA, 1-hexadecene and LA as ISR-related compounds. This study shows that KUDC1013 has a great potential as biological control agent because of its multiple factors involved in induction of systemic resistance against phytopathogens.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1990년도 추계학술대회 논문집 학회본부
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• pp.45-48
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• 1990

This paper deals with the control strategy for constant voltage, constant frequency (CVCF) generation of doubly-fed Induction generator. As induction machine is a nonlinear and multivariable machine, so, the influential factors for CVCF generation of induction generator are the magnitude of output voltage, load current and its power factor, slip of the machine, etc. To get appropriate control scheme and to research the effect of its parameters, the control equation of induction machine is derived and tested. The derived condition is very useful for the CVCF control of the machine and for determing the characteristics of the system. The simulation results show that magnetizing reactance and rotor resistance is a very important parameter in this control system.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2008년도 추계학술대회
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• pp.167-176
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• 2008

The recent dramatic growth of ERP has changed the way organizations conduct their businesses, and resulted in significant tangible and intangible benefits being realized by participating firms. Despite these various benefits, firms still have problems in implementing and diffusing ERP due to some reasons, such as resistance to the change. This study primarily aims at identifying what factors are significantly affecting the diffusion of ERP system and finding out how these identified factors can be effectively managed.

• 산업진흥연구
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• 제8권1호
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• pp.11-22
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• 2023

본 연구는 잘못된 자세 습관으로 인해 발생하는 근골격계 질환의 통증을 관리하기 위해 스스로 일상에서 바른 자세를 유지할 수 있도록 돕는 서비스 디자인 콘텐츠를 제안하고 있다. 현대인의 대표적 질환인 근골격계 질환과 바른 자세 실천에 대한 현황을 분석하기 위해 143명에 대한 설문 및 1차-2차 고정카메라 기법을 활용하였다. 연구결과 바른 자세 실천을 저해하는 저항 요인과 바른 자세 실천을 강화하는 유도 요인을 도출하였으며 저항 요인을 감소시키고 유도 요인을 증가시키는 것이 바른 자세 실천에 긍정적인 영향을 주는 것을 검증하였다. 이를 바탕으로 근전도 센서와 웨어러블 기기를 활용하여 현대인들이 바른 자세를 실천 및 관리하는 데 유의미한 앱 서비스를 제안하였다. 본 연구는 사용자의 자세 습관 분석을 통한 자기 객관화 바탕으로 서비스 콘텐츠 제안을 통해 일상에서 스스로 바른 자세를 실천 및 유지할 수 있도록 도와줌으로써 근골격계 통증을 완화시키고 나아가 삶의 질을 개선시키는데 그 의의가 있다.

• 약학회지
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• 제52권1호
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• pp.67-72
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• 2008

The use of doxorubicin, which is one of the most effective anticancer agents, is often limited by occurrence of acquired resistance in tumor cells. GSH has been shown to be involved in the development of this drug resistance. Transcription factor Nrf2 governs the expression of GSH synthesizing glutamylcysteine ligase (GCL), as well as multiple phase 2 detoxifying enzymes. Here we show that Nrf2 is one of factors determining doxorubicin sensitivity. Nrf2-deficient fibroblasts (murine embryonic fibroblasts, MEF) were more susceptible to doxorubicin mediated cell death than wild-type cells. Doxorubicin treatment elevated levels of Nrf2-regulated genes including NAD(P)H: quinone oxidoreductase (Nqo1) and GCL in wild-type fibroblasts, while no induction was observed in Nrf2-deficient cells. Doxorubicin resistance in human ovarian SK-OV cells was reversed by treatment with L-buthionine-sulfoxamine (BSO), which is depleting intracellular GSH. Finally, transfection of SK-OV cells with Nrf2 siRNA resulted in exacerbated cytotoxicity following doxorubicin treatment compared to scrambled RNA control. These results indicate that the Nrf2 pathway, which plays a protective role in normal cells, can be a potential target to control cancer cell resistance to anticancer agents.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2010년도 춘계학술대회 논문집
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• pp.1383-1388
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• 2010

The latest generation of tram is low-floor design, various nations in europe and japan have developed battery driven hybrid trams that combine battery and wiring. Battery driven tram system is achieved by contactless power supply system, thus system is needed high efficiency, high power and low weight traction motor for maximization of energy efficiency. Research from abroad is still in induction motor(IM) application, and it is not meet the efficiency and the power per unit volume in IPMSM. In this paper, we design compare IM and IPMSM to apply battery driven tram, and then compare these motors. To design the motor, we estimate the loading condition at first. Loading condition includes rolling resistance, air-drag resistance, and slope resistance. Based on the loading condition by estimation, we determine the power and compute rated voltage and rated current. In this paper, voltage is limited by battery voltage level. As a result, volume about IM is 1.98 times bigger than IPMSM under same condition. Even though IPMSM is bigger than IM in power density per volume, we consider more factors for actual application because there are demagnetization of permanent magnet in IPMSM and so on by external environment conditions.

• 센서학회지
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• 제4권4호
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• pp.29-40
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• 1995

본논문(本論文)에서는 정전유도(靜電誘導) 트랜지스터의 잡음원인분석(雜音原因分析)을 위하여 직류(直流) 및 잡음특성(雜音特性), 잔존성분(殘存成分), 입력용량등(入力容量等)의 정무화(定武化)에 필요(必要)한 잡음(雜音) 등가회로(等價回路)를 제안(提案)하였다. 가장 단순(單純)한 잡음(雜音) 등가회로(等價回路)는 정전유도(靜電誘導) 트랜지스터의 동작원리(動作原理)에 의한 모델이며, 이 모델에 의한 실측치(實測値)가 산탄(shot) 잡음(雜音)보다 작게 나타났다. 소스 저항(抵抗)이 삽입(揷入)된 등가회로(等價回路)에서는 소스 저항(抵抗)의 부귀환효과(負歸還效果)에 의하여 산탄 잡음(雜音)이 저감(低減)됨을 확인(確認)하였다. 정확(正確)한 잡음저감원인(雜音低減原因)을 분석(分析)하기 위하여 소스 저항(抵抗)과 드레인 저항(低抗)의 계산식(計算式)을 유도(誘導)하기 위한 등가회로(等價回路)를 제안(提案)하였다. 등가회로(等價回路) 확인(確認) 실험(實驗)에서는 잔존성분(殘存成分)에 대한 신호원저항(信號源抵抗)과 출력부하저항(出力負荷抵抗)의 영향(影響)은 작으며, 잔존성분(殘存成分)은 입력환산등가잡음저항(入力換算等價雜音抵抗)으로 나타낼 수 있다. 또한, 입력용량(入力容量)은 부하저항(負荷抵抗)이 $0{\Omega}$일 때 13.6pF이며, 게이트 배선등(配線等) 정전유도(靜電誘導) 트랜지스터 동작(動作)에 직접(直接) 관여(關與)하지 않는 용량(容量)은 10pF정도(程度)이다.

• 한국초전도ㆍ저온공학회논문지
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• 제23권4호
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• pp.61-69
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• 2021

This paper presents the analysis and experiment results on the electrical and thermal characteristics of metal insulation (MI) REBCO racetrack coil, which was wound with stainless steel (SS) tape between turn-to-turn layers, under rotating magnetic field and conduction cooling system. Although the field windings of superconducting rotating machine are designed to operate on a direct current, they may be subjected to external magnetic field due to the unsynchronized armature windings during electrical or mechanical load fluctuations. The field windings show the voltage and magnetic field fluctuations and the critical current reduction when they are exposed to an external magnetic field. Moreover, the cryogenic cooling conditions are also identified as the factors that affect the electrical and thermal characteristics of the HTS coil because the characteristic resistance changes according to the cryogenic cooling conditions. Therefore, it is necessary to investigate the effect of external magnetic field on the electrical and thermal characteristics of MI-SS racetrack coil for further development reliable HTS field windings of superconducting rotating machine. First, the major components of the experiment test (i.e., HTS racetrack coil construction, armature winding of 75 kW class induction motor, and conduction cooling system) were fabricated and assembled. Then, the MI racetrack coil was performed under liquid nitrogen bath and conduction cooling conditions to estimate the key parameters (i.e., critical current, time constant, and characteristic resistance) for the test coil in the steady state operation. Further, the test coil was charged to the target value under conduction cooling of 35 K then exposed to the rotating magnetic field, which was generated by three phrase armature windings of 75 kW class induction motor, to investigate the electrical and thermal characteristics during the transient state.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.480-480
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• 2000

In this paper, we proposed a fuzzy-neuro controller to control the speed of wound rotor induction motor with slip energy recovery. The speed is limited at some range of sub-synchronous speed of the rotating magnetic field. Control speed by adjusting resistance value in the rotor circuit that occurs the efficiency of power are reduced, because of the slip energy is lost when it passes through the rotor resistance. The control system is designed to maintain efficiency of motor. Recently, the emergence of artificial neural networks has made it conductive to integrate fuzzy controllers and neural models for the development of fuzzy control systems, Fuzzy-neuro controller has been designed by integrating two neural network models with a basic fuzzy logic controller. Using the back propagation algorithm, the first neural network is trained as a plant emulator and the second neural network is used as a compensator for the basic fuzzy controller to improve its performance on-line. The function of the neural network plant emulator is to provide the correct error signal at the output of the neural fuzzy compensator without the need for any mathematical modeling of the plant. The difficulty of fine-tuning the scale factors and formulating the correct control rules in a basic fuzzy controller may be reduced using the proposed scheme. The scheme is applied to the control speed of a wound rotor induction motor process. The control system is designed to maintain efficiency of motor and compensate power factor of system. That is: the proposed controller gives the controlled system by keeping the speed constant and the good transient response without overshoot can be obtained.

• IMMUNE NETWORK
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• 제14권6호
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• pp.296-306
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• 2014

There is growing evidence that crosstalk between mantle cell lymphoma (MCL) cells and stromal microenvironments, such as bone marrow and secondary lymphoid tissues, promotes tumor progression by enhancing survival and growth as well as drug resistance of MCL cells. Recent advances in the understanding of lymphoma microenvironment have led to the identification of crucial factors involved in the crosstalk and subsequent generation of their targeted agents. In the present study, we evaluated the combinatory effect of blocking antibodies (Ab) targeting CXCR4 and VLA-4, both of which were known to play significant roles in the induction of environment-mediated drug resistance (EMDR) in MCL cell line, Jeko-1. Simultaneous treatment with anti-CXCR4 and anti-VLA-4 Ab not only reduced the migration of Jeko-1 cells into the protective stromal cells, but also enhanced sensitivity of Jeko-1 to a chemotherapeutic agent to a greater degree than with either Ab alone. These combinatorial effects were associated with decreased phosphorylation of ERK1/2, AKT and NF-${\kappa}B$. Importantly, drug resistance could not be overcome once the adhesion of Jeko-1 to the stromal occurred despite the combined use of Abs, suggesting that the efforts to mitigate migration of MCLs should be attempted as much as possible. Our results provide a basis for a future development of therapeutic strategies targeting both CXCR4 and VLA-4, such as Ab combinations or bispecific antibodies, to improve treatment outcomes of MCL with grave prognosis.