• Title/Summary/Keyword: Resistance

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Investigation on antimicrobial resistance genes of Salmonella Schwarzengrund isolated from pigs (돼지유래 Salmonella Schwarzengrund의 약제내성 유전자에 관한 연구)

  • Lee, Woo-Won;Kim, Sang-Hyun;Lee, Seung-Mi;Lee, Gang-Rok;Lee, Gi-Heun;Kim, Yong-Hwan
    • Korean Journal of Veterinary Service
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    • v.35 no.1
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    • pp.1-8
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    • 2012
  • To detect the virulence genes (invA and spvC) and antimicrobial resistance genes, polymerase chain reaction (PCR) was carried out using total 67 strains of S. Schwarzengrund isolated from pigs. As results, invA was detected from all 67 strains of S. Schwarzengrund, however, spvC was not at all. All 12 strains with ampicillin resistance, 15 strains with chloramphenicol resistance, 9 strains with kanamycin resistance, 1 strain with sulfamethoxazole/trimethoprim resistance, and 66 (98.5%) of 67 strains with tetracycline resistance carried TEM (${\beta}$-lactamase $bla_{TEM}$), cmlA (nonenzymatic chloramphenicol resistance), aphA1-Iab (aminoglycoside phosphotransferase), sulII (dihydropteroate synthase), and tetA (class A tetracycline resistance), respectively. All 63 strains with streptomycin resistance carried 3 aminoglycoside resistance genes, including aadA (aminoglycoside adenyltransferase), strA, and strB (streptomycin phosphotransferase). With respect to prevalence of antibiotic resistance genes occurred in S. Schwarzengrund, genes for strB (46.0%); strA and strB (30.2%); aadA, strA, and strB (9.5%); strA (7.9%); aadA and strB (3.2%); and aadA (3.2%) were detected by PCR.

Comparison of Antimicrobial Resistance and Multi-Drug Resistance Patterns of Escherichia coli Isolated from Aquatic Organisms Off the West Coast of South Korea (서해안 수산생물에서 분리한 대장균(Escherichia coli)의 항생제 내성 및 다제 내성 양상 비교)

  • Jeong, Yeon Gyeom;Park, Bo Mi;Kim, Min Ju;Park, Jin Il;Jung, Yeoun Joong;Oh, Eun Gyoung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.4
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    • pp.388-396
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    • 2021
  • Antimicrobial resistance patterns of Escherichia coli were investigated. Strains were isolated from 310 shellfish, 36 crustaceans, and 12 fish collected off the West Coast of Korea from April 2019 to October 2020. Two hundred and ninety-five E. coli strains were isolated from shellfish, 100 from crustaceans, and 54 from fish. Strains isolated from shellfish showed the highest resistance to ampicillin (27.5%), whereas those from crustaceans were resistant to sulfisoxazole (30.0%) and those from fish were resistant to ampicillin (59.3%) and sulfisoxazole (59.3%). Ceftazidime resistance was observed in strains isolated from short neck and hard clams, whereas gentamicin resistance was observed in strains from fish. Multi-drug resistance was observed in 56 strains (48.7%) isolated from shellfish, 11 (28.2%) from crustaceans and 27 (73.0%) from fish. Depending on the source of isolation, the strains showed specific antimicrobial resistance tendency. Strains isolated from shellfish showed 12 different multi-drug resistance patterns, whereas those from crustaceans showed high resistance (59%) to a single antimicrobial agent and those from fish showed a broad trend of multi-drug resistance to more than eight antimicrobials.

A Study on the Resistance of Individuals in the Organization when Information Technology is introduced (정보기술도입(情報技術導入)에 따른 조직구성원(組織構成員)의 저항(抵抗)에 관한 연구(硏究))

  • Lee Jae-Yeol
    • Management & Information Systems Review
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    • v.1
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    • pp.41-73
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    • 1997
  • Responses from the information users on the information technology are very important considerations when majority of the companies are going to introduce information technology by way of computers. When new information technology is introduced, resistance from the information users are likely to be happen and if suitable management about this is not carried out, resistance from the users of information technology will be continued. It is needed for the companies to minimize user's resistance about the information technology to reduce the introduction cost of information technology and to elevate the degree of use. To reduce the resistance from the users about information technology, factors which affect the resistance of users should be analyzed first and it will be effective to control those factors later on. Therefore it will be meaningful for the successful management of information technology if several factors which affect the resistance of users about information technology are searched out and managed. The purpose of this study is to find various factors which affect the resistance of the individuals in the organization about information technology in the process of introducing information technology. The relationship between the factors and factors which affect indirectly to the information technology are the things which are supposed to be considered to the companies who are going to introduce information technology in the long run. Instead of decreasing the resistance directly, let individuals in the organization decreases the resistance by themselves is a more effective way and may have less side effects, in terms of controlling the members in the organization.

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Effects of Trim Conditions on Ship Resistance of KCS in Short Waves (단파장 영역에서 운항 자세가 KCS의 선체 저항에 미치는 영향)

  • Kim, Yeoun Joo;Lee, Sang Bong
    • Journal of the Society of Naval Architects of Korea
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    • v.54 no.3
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    • pp.258-266
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    • 2017
  • Numerical simulations of turbulent two phase flows around KCS have been performed to investigate effects of trim conditions on ship resistance of KCS in short waves by utilizing waves2foam. The wave lengths of LPP/2 and LPP/4 with 1m and 2m wave heights were imposed at inlet boundary. The resistance reduction at 2m trim by head and the increase of resistance at trims by stern were observed regardless of wave lengths and wave heights. The hull pressure on fore-and-aft rather than wave patterns around bulbous bows was mainly responsible for the total resistance coefficients of KCS in short waves. A phase diagram of contribution of hull pressure to the total resistance coefficients disclosed that the phase of representing the maximum resistance in time history played an important role in the effect of trim conditions on ship resistance of KCS in short waves.

Pullout Resistance by Horizontal Spacing of Geosynthetic Strip (띠형 섬유보강재의 설치간격에 따른 인발저항 특성에 관한 연구)

  • Han, Jung-Geun;Yoon, Won-Il;Hong, Ki-Kwon;Lee, Kwang-Wu;Kim, Ju-Hyong;Cho, Sam-Deok
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.09a
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    • pp.315-324
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    • 2010
  • In this study, the pullout tests are conducted to evaluate the pullout resistance of the geosynthetic strip with or without bearing resistance zone. The test results are indicated that the pullout resistance of the geosynthetic strip without bearing resistance zone is not affected by horizontal spacing. However, the horizontal spacing of reinforcement with bearing resistance zone affects the bearing resistance. In other words, it is indicated that the bearing resistance at spacing of 210mm is larger than that at spacing of 260mm. This means that the pullout strength at spacing of 210mm is larger than that at spacing of 260mm. Therefore.

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Innovation resistance and adoption regarding a virtual reality motion-sensing input device (가상현실 모션센싱 입력장치에 대한 혁신 저항과 수용)

  • Park, Hyun-jung;Choi, Jaewon;Shin, Kyung-shik
    • Knowledge Management Research
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    • v.16 no.4
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    • pp.191-213
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    • 2015
  • With the advancement of virtual reality technology, virtual reality contents and devices are being competitively released. This research deals with an early stage adoption model of a motion-sensing input device which enhances the user experience of these virtual reality contents and devices. In contrast to the previous research on the adoption or resistance of innovative products, this work compares and analyzes the antecedents in MIR(Model of Innovation Resistance) of resistance-perspective as well as those in UTAUT2(Extended Unified Theory of Acceptance and Use of Technology) and IDT(Innovation Diffusion Theory) of adoption-perspective, and suggests a resistance-incorporated adoption model from a new viewpoint. The analysis of questionnaire data indicates the following results: Performance expectancy, effort expectancy, price value, hedonic motivation in UTAUT2 and visibility in IDT have a significant negative influence on innovation resistance. Compatibility in IDT and MIR exerts a positive influence on perceived value. Social influence and hedonic motivation in UTAUT2 positively relates to perceived value. Higher innovation resistance results in lower perceived value, with innovation resistance and perceived value negatively and positively affecting intention to use, respectively.

The relationship between muscle mitochondrial nutritional overloading and insulin resistance

  • Jeon, Jae-Han;Moon, Jun-Sung;Won, Kyu-Chang;Lee, In-Kyu
    • Journal of Yeungnam Medical Science
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    • v.34 no.1
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    • pp.19-28
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    • 2017
  • The incidence of type 2 diabetes mellitus and insulin resistance is growing rapidly. Multiple organs including the liver, skeletal muscle and adipose tissue control insulin sensitivity coordinately, but the mechanism of skeletal muscle insulin resistance has not yet been fully elucidated. However, there is a growing body of evidence that lipotoxicity induced by mitochondrial dysfunction in skeletal muscle is an important mediator of insulin resistance. However, some recent findings suggest that skeletal mitochondrial dysfunction generated by genetic manipulation is not always correlated with insulin resistance in animal models. A high fat diet can provoke insulin resistance despite a coordinate increase in skeletal muscle mitochondria, which implies that mitochondrial dysfunction is not mandatory in insulin resistance. Furthermore, incomplete fatty acid oxidation by excessive nutrition supply compared to mitochondrial demand can induce insulin resistance without preceding impairment of mitochondrial function. Taken together we suggested that skeletal muscle mitochondrial overloading, not mitochondrial dysfunction, plays a pivotal role in insulin resistance.

Studies of the Insecticide Resistance in the Green Peach Aphid, Myzus persicae Sulzer (V). Development of Cypermethrin and Pirimicarb Resistance, and Cross Resistance (복숭아혹진딧물의 살충제 저항성에 관한 연구 (V). Cypermethrin과 Pirimicarb에 의한 저항성 발달과 교류저항성)

  • 최승윤;김길하;안용준
    • Korean journal of applied entomology
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    • v.28 no.1
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    • pp.23-27
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    • 1989
  • The green peach aphid(Myzus pericae Sulzer) was selected over 20 generations with cypermethrin and pirmicarb, respectively. The resulting resistant strains were tested to inverting-ate the development of insecticide resistance and cross-resistance to some insecticides in the laboratory. The development of insecticide resistance against green peach aphid at the 20th selected generation was greatly varied with the insecticides: 20.5 fold for cypermethrin and 3.2 fold for pirimicarb compared with the parent strain. The cypermethrin selected strain exhibited cross resistance to acephate and pirimicarb, and pirimicarb selected strain to acephate and cypermethrin, respectively. Demeton-S-methyl, however, has not been shown cross-resistance by the selected strains.

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Prevalence of Aspirin Resistance and Clinical Characteristics in Patients with Cerebral Infarction

  • Choi, Jong-Tae;Shin, Kyung-A;Kim, Young-Kwon
    • Biomedical Science Letters
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    • v.19 no.3
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    • pp.233-238
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    • 2013
  • Aspirin is still the mainstay of antiplatelet therapy in the cardiovascular and cerebrovascular disease. However, some patients are not responsive to the antithrombotic action of aspirin. The aim of this study was to assess the prevalence and clinical characteristics of aspirin resistance in patients with cerebral infarction. We tested platelet function in 557 patients who had been treated with aspirin in J general hospital. Platelet function was tested using the multiple electrode platelet aggregometry (MEA). Platelet reactivity was expressed as area under the aggregation curve (AUC, U) and >30 AUC was defined as aspirin resistance. Aspirin resistance was detected in 16.2% patients. There was not any significant differences in age, gender between aspirin resistance and aspirin sensitive patients. WBC was significantly higher in patients with aspirin resistance (P < .05). HDL-cholesterol was significantly higher in patients with aspirin sensitive (P < .05). Aspirin resistance was positive correlation with platelet count (r =.314, P =.003). The prevalence of aspirin resistance in cerebral infarction was 16.2%, and platelet count were related with aspirin resistance.

A Study on Decreasing of Sliding Noise of a Carbon Film Variable Resistor (탄소 피막 가변 저항기의 접동 잡음 감소에 관한 연구)

  • 윤재강
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.20 no.1
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    • pp.50-54
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    • 1983
  • Contact resistance variation which may be called sliding noise in carbon film variable resistors whose resistance elements consists of linear resistivity distribution were measured with several kinds of sliders and were analyzed to reduce the contact resistance variation. About the measuring method, the standard method of measuring contact resistance variation specified by the variable Resistance Components Institute was adupted. By analyzing the experimental results, it has been shown that the primary cause of contact resistance variation is due to current constriction and small discharge sparks in the resistance film in the area close to the slide contact. Moreover, it has been found that the sliding noise would be reduced by increasing the number of contact points, sliding speed, and pressure, and by using some kinds of insulation oil on the contacting surface. High contact resistance variation is likely to occur in the area of high resistance variation in a logrithmic resistance taper.

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