• Bulletin of the Korean Chemical Society
• /
• 제31권11호
• /
• pp.3291-3296
• /
• 2010

A gelastatins (1), natural MMP inhibitors, and their hydroxamate analogues (2) in TACE enzyme evaluated for discovery of potent TACE inhibitors. We have employed molecular dynamics simulations to compute the relative free energy of hydration and binding to TACE for gelastatin (1) and its hydroxamate analogue (2). The relative free energy difference is directly described in this article using the free energy perturbation approach as a means to accurately predict the TACE inhibitor of gelastatin analogues. The results show that the good agreement between the experimental and theoretical relative free energies of binding, gelastatin hydroxamate (2) binds stronger to TACE by -3.37 kcal/mol. The desolvation energy costs significantly reduced binding affinity, hydroxamate group associated with high desolvation energy formed strong favorable interactions with TACE with more than compensated for the solvation costs and therefore led to an improvement in relative binding affinity.

• 한국안전학회지
• /
• 제16권3호
• /
• pp.99-105
• /
• 2001

This paper presents results km a series of model tests oil vertically loaded single piles to compare the behaviors of H and pipe piles under the same ground condition. The aims of this paper were to compare the bearing capacity of H-pile md pipe piles under in the same ground condition and to estimate the effect of gravity acceleration and relative soil density. Relative density of soil were made to be 40%, 80% and embedded length of pile on sand was increased by 10, 12, 14, 16 times of the diameter of pile, respectively. As a results of test series, allowable load of H-pile is from 6.4% to 18.2% larger than allowable load of pipe pile in relative density 80% and from 9.1% to 39.4% larger than allowable load of pipe pile in relative density 40%. As a results of numerical analysis, we were predicted behaviour of stress-displacement of pile with model test. In the case of relative density 80% and 40%, bearing capacity of H pile represent from 17.74% to 18.6% larger than allowable load of pipe pile.

• 호남수학학술지
• /
• 제40권3호
• /
• pp.509-519
• /
• 2018

In this paper, we introduce a new class of reciprocal convex set which is called as relative reciprocal convex set. We establish a necessary and sufficient condition for the minimum of the differentiable relative reciprocal convex function. This condition can be viewed as a new class of variational inequality which is called relative reciprocal variational inequality. Using the auxiliary principle technique we discuss the existence criteria for the solution of relative reciprocal variational inequality. Some special cases which are naturally included in our main results are also discussed.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2004년도 춘계학술대회
• /
• pp.899-904
• /
• 2004

Multibody dynamics formulation has been developed based on relative cartesian coordinates for subsystem analysis. Relative cartesian coordinates are defined with respect to a reference body of a subsystem. Relative cartesian formulation inherits the same merits of absolute cartesian formulation, such as generality and easy implementation. Two methods have been applied. One is Largrange Multiplier Elimination method and the other is independent coordinate method. A 1/4 car simulation has been carried out to verify the formulations. Since both methods provide identical results, it proves the validity of the formulation.

• 전기학회논문지
• /
• 제60권3호
• /
• pp.625-631
• /
• 2011

This paper presents a discrete-time output feedback consensus algorithm for Multi-Agent Systems (MAS). Under the assumption that an agent is aware of the relative state information about its neighbors, a state feedback consensus algorithm is designed based on Linear Matrix Inequality (LMI) method. In general, however, it is possible to obtain its relative output information rather than the relative state information. To reconcile this problem, an Unknown Input Observer (UIO) is employed in this paper. To this end, first it is shown that the relative state information can be estimated using the UIO and the measured relative output information. Then a certainty-equivalence type output feedback consensus algorithm is proposed by combining the LMI-based state feedback consensus algorithm with the UIO. Finally, simulation results are given to illustrate that the proposed method successfully achieves the state consensus.

• 한국실내디자인학회:학술대회논문집
• /
• 한국실내디자인학회 2005년도 추계학술발표대회 논문집
• /
• pp.161-164
• /
• 2005

The concept of Space-time is performed while the movement of human Is imaged on coming 20th century up. Specifically it is considered that the movement of human is caused by the relativistic otherness rather than an absolute subject in space of deconstructive tendency. The purpose of this study is that I try to analyze an expression of relative space-time concept in desconstructive tendency and I have to get a concept how this kind of expression effect the contemporary commercial space. Through this study, I can get to know that the expression of relative space-time concept expresses the dynamic construction by the indeterminacy and the visual effect by the dematerialization in the contemporary commercial interior-space. According to the result of study, the concept of space get to be more meaningful, relative space-time concept and it can be attributed to the concept of human's new creative space over human's life in general.

• 한국전기전자재료학회논문지
• /
• 제24권3호
• /
• pp.224-228
• /
• 2011

This research, integratable capacitive relative humidity sensor was produced using polyimide on glass substrate. Also, at the time of upper electrode formation, upper electrode grain size was affected by giving changes to sputtering condition. Through this analyzing electrical characteristics affect from capacitive relative humidity sensor was possible. Capacitance of capacitive relative humidity sensor was 330 pF, linearity of 0.6%FS and it showed less than 3% of low hysterisis. Specially, hysterisis was affected more from interface than interstitial. Also was affected by the grain size which is one of the formation condition of upper electrode.

• Journal of Mechanical Science and Technology
• /
• 제20권2호
• /
• pp.177-184
• /
• 2006

An orbital design method of the formation initialization based on the relative orbital element method is presented. It firstly constructed the relative motion equation of the satellite formation flying in terms of the leader and followers' orbital elements. Then the equation was simplified when the orbit eccentricity of the leader satellite was small. And according to the satellites' mission, a general design method for the relative trajectory was proposed. The advantage of this method is that one can get a very simple analytical formula of each follower satellite's orbital elements when the orbital eccentricity of the leader satellite is zero. The simulation results show that the method is effective.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2008년도 추계학술대회 논문집
• /
• pp.1065-1068
• /
• 2008

Concrete is still one most common construction materials even in railway structures. As structures become massive and mega-sized, the importance of early age concrete quality control becomes more significant. Among various factors, relative humidity and temperature are the primary factors governing the early age quality. Temperature raise due to cement hydration causes stress, which can develop to cracking with internal and/or external restraints. Exposure conditions including ambient temperature, humidity and wind also significantly affect the cracking behavior of early age concrete. Among many of studies on the early age concrete behavior, investigation on the variation of temperature and relative humidity internal of concrete is not common. That is in part because the difficulties in measuring the relative humidity and temperature inside the concrete. This study used a digital sensor with an appropriate logger to measure internal temperature and relative humidity. This direct measuring method is expected to provide more reliable and comprehensive data acquisition on the early age behavior of concrete.

• East Asian mathematical journal
• /
• 제37권5호
• /
• pp.613-617
• /
• 2021

Abstract. For a positive square-free integer m, let K = ℚ($\sqrt{m}$) be a real quadratic field. The relative class number H_d(f) of K of discriminant d is the ratio of class numbers 𝒪_K and 𝒪_f, where 𝒪_K is the ring of integers of K and 𝒪_f is the order of conductor f given by ℤ + f𝒪_K. In 1856, Dirichlet showed that for certain m there exists an infinite number of f such that the relative class number H_d(f) is one. But it remained open as to whether there exists such an f for each m. In this paper, we give a result for existence of real quadratic field ℚ($\sqrt{m}$) with relative class number one where the period of continued fraction expansion of $\sqrt{m}$ is 6.