• IMMUNE NETWORK
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• v.11 no.4
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• pp.203-209
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• 2011

Background: T cell immunoglobulin mucin containing molecule (TIM)-3 is expressed in differentiated Th1 cells and is involved in the suppression of the cytokine production by these cells. However, the regulation of the expression of other T cell genes by TIM-3 is unclear. Herein, we attempted to identify differentially expressed genes in cells abundantly expressing TIM-3 compared to cells with low expression of TIM-3. Methods: TIM-3 overexpressing cell clones were established by transfection of Jurkat T cells with TIM-3 expression vector. For screening of differentially expressed genes, gene fishing technology based on reverse transcription-polymerase chain reaction (RT-PCR) using an annealing control primer system was used. The selected candidate genes were validated by semi quantitative and real-time RT-PCR. Results: The transcription of TIMP-1, IFITM1, PAR3 and CCL1 was different between TIM-3 overexpressing cells and control cells. However, only CCL1 transcription was significantly different in cells transiently transfected with TIM3 expression vector compared with control cells. CCL1 transcription was increased in primary human $CD4^+$ T cells abundantly expressing TIM-3 but not in cells with low expression of TIM-3. Conclusion: CCL1 was identified as a differentially transcribed gene in TIM-3-expressing $CD4^+$ T cells.

• IMMUNE NETWORK
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• v.12 no.5
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• pp.207-212
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• 2012

T cell immunoglobulin mucin domain (TIM)-3 is an immunomodulatory molecule and upregulated in T cells by several cytokines. TIM-3 also influences mast cell function but its transcriptional regulation in mast cells has not been clarified. Therefore, we examined the transcript level and the promoter activity of TIM-3 in mast cells. The TIM-3 transcript level was assessed by real-time RT-PCR and promoter activity by luciferase reporter assay. TIM-3 mRNA levels were increased in HMC-1, a human mast cell line by TGF-${\beta}1$ stimulation but not by stimulation with interferon (IFN)-${\alpha}$, IFN-${\lambda}$, TNF-${\alpha}$, or IL-10. TIM-3 promoter -349~+144 bp region relative to the transcription start site was crucial for the basal and TGF-${\beta}1$-induced TIM-3 promoter activities in HMC-1 cells. TIM-3 promoter activity was increased by over-expression of Smad2 and Smad4, downstream molecules of TGF-${\beta}1$ signaling. Our results localize TIM-3 promoter activity to the region spanning -349 to ＋144 bp in resting and TGF-${\beta}1$ stimulated mast cells.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.6
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• pp.2922-2945
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• 2018

Achieving efficient authentication is a crucial issue for stream data commonly seen in content delivery, peer-to-peer, and multicast/broadcast networks. Stream authentication mechanisms need to be operated efficiently at both sender-side and receiver-side at the same time because of the properties of stream data such as real-time and delay-sensitivity. Until now, many stream authentication mechanisms have been proposed, but they are not efficient enough to be used in stream applications where the efficiency for sender and receiver sides are required simultaneously since most of them could achieve one of either sender-side and receiver-side efficiency. In this paper, we propose an efficient stream authentication mechanism, so called TIM, by integrating Trapdoor Hash Function and Merkle Hash Tree. Our construction can support efficient streaming data processing at both sender-side and receiver-side at the same time differently from previously proposed other schemes. Through theoretical and experimental analysis, we show that TIM can provide enhanced performance at both sender and receiver sides compared with existing mechanisms. Furthermore, TIM provides an important feature for streaming authentication, the resilience against transmission loss, since each data block can be verified with authentication information contained in itself.

• MALSORI
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• no.51
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• pp.85-98
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• 2004

It is almost impossible to generate the sound field effect in real time with the time-domain linear convolution because of its large multiplication operation requirement. To solve this, three methods are introduced to reduce the number of multiplication operations in this paper. Firstly, the time-domain linear convolution is replaced with the frequency-domain circular convolution. In other words, the linear convolution result can be derived from that of the circular convolution. This technique reduces the number of multiplication operations remarkably, Secondly, a subframe concept is introduced, i.e., one original frame is divided into several subframes. Then the FFT is executed for each subframe and, as a result, the number of multiplication operations can be reduced. Finally, the QFT is used in stead of the FFT. By combining all the above three methods into our final the SFE generation algorithm, the number of computations are reduced sufficiently and the real-time SFE generation becomes possible with a general PC.

• Journal of the Korea Convergence Society
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• v.3 no.1
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• pp.1-5
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• 2012

In this paper, we developed real-tim video transfer system based on Android environment. After android device with embedded camera capture images, it sends image frames to video server system. And also video server transfer the images from client to peer client. Peer client also implemented on android environment. We can send 16 image frames per second without any loss in 3G mobile network environment.

• Journal of Satellite, Information and Communications
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• v.10 no.4
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• pp.83-86
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• 2015

In this paper, we propose a real-tim measurement management system UI development linked the Water treatment facilities broadband Convergence Network. The sensor and the image data received by the server develop a program to interact with Web through water treatment facilities broadband convergence network. So, Separately develop UI capable of independently operating. Building a web server for remote monitoring of the transmission sensor and the image data. And Monitoring and control is possible the sensor data and image data through the Web-based UI. We can grasp the current state such as measurement time, concentration and depth of interface through the proposed real-time measurement management system UI development liked the water treatment facilities broadband convergence network. So, we can check in whether the normal operation of water treatment facilities and whether the casualties such as fire and security. As well as real time to see the information at a glance due to UI development can be raal-time monitoring of real-time measurement management system.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.11
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• pp.913-919
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• 2005

An advanced method of Relaxed Static Stability (RSS) is utilized for improving the aerodynamic performance of modem version supersonic jet fighter aircraft. The flight control system utilizes RSS criteria in both longitudinal and lateral-directional axes to achieve performance enhancements and improve stability. Standard CLDA (Control Law Design and Analysis) process is provided that reduce the development period of the flight control system. In addition, if this process is employed in developing flight control laws, it reduces the trial and error development and verification of control laws. This paper details the design process of developing a flight control law for the RSS aircraft, utilizing military specifications, linear and nonlinea, analysis using XMATH and ATLAS(Aircraft, Tim Linear and Simulation), handling quality tests using the HQS (Handling Quality Simulator), and real flight test results to verify aircraft dynamic flight responses.

• Communications for Statistical Applications and Methods
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• v.25 no.4
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• pp.431-442
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• 2018

This paper highlights the computational explosion issues in the autoregressive moving average approach of frequency estimation of sinusoidal data with a large sample size. A new algorithm is proposed to circumvent the computational explosion difficulty in the conditional least-square estimation method. Notice that sinusoidal pattern can be generated by a non-invertible non-stationary autoregressive moving average (ARMA) model. The computational explosion is shown to be closely related to the non-invertibility of the equivalent ARMA model. Simulation studies illustrate the computational explosion phenomenon and show that the proposed algorithm can efficiently overcome computational explosion difficulty. Real data example of sunspot number is provided to illustrate the application of the proposed algorithm to the time series data exhibiting sinusoidal pattern.

• ETRI Journal
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• v.38 no.5
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• pp.911-921
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• 2016

This paper presents the description, practical implementation, and stability analysis of a recently proposed, energy-efficient, medium access control protocol for wireless sensor networks, ALOHA-Q, which employs a reinforcement-learning framework as an intelligent transmission strategy. The channel performance is evaluated through a simulation and experiments conducted using a real-world test-bed. The stability of the system against possible changes in the environment and changing channel conditions is studied with a discussion on the resilience level of the system. A Markov model is derived to represent the system behavior and estimate the time in which the system loses its operation. A novel scheme is also proposed to protect the lifetime of the system when the environment and channel conditions do not sufficiently maintain the system operation.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.1
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• pp.91-96
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• 2010

Concentric mosaics are made with arranging and summing of video frames by using common spacial standards. Compared with previous works on 3-D wavelet transform coding, we have made important design considerations to enable flexible partial decoding and bit-stream random access. A just-in-time(JIT) rendering engine of the compressed concentric mosaic is developed. However, computationally, it is still demanding to accomplish the real-time rendering. Only the contents for specific scene representation are need to be decoded by maintaining compressed data. Thus our proposed algorithm is able to render real concentric mosaic by using lifting scheme instead of wavelet transform.