• 제목/요약/키워드: RCT(randomized controlled trials)

검색결과 212건 처리시간 0.021초

후관절 증후군의 침 치료에 대한 문헌 연구 보고 (Acupuncture for Facet Joint Syndrome: A Review of Clinical Study)

  • 구지향
    • 한방재활의학과학회지
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    • 제33권1호
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    • pp.13-29
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    • 2023
  • Objectives To evaluate the evidence supporting the effectiveness of acupuncture for facet joint syndrome. Methods We conducted search across 9 electronic databases (PubMed, EMBASE, Cochrane CENTRAL (CENTRAL), KoreaMed, Kmbase, Koreanstudies Information Service System (KISS), ScienceOn, China National Knowledge Infrastructure (CNKI), and Wanfang) to find clinical trials that used acupuncture as treatment for facet joint syndrome. The methodological quality of randomized controlled clinical trials (RCTs) were assessed using the Cochrane Risk of Bias (RoB) tool, while non-randomized controlled clinical trials (nRCTs) were assessed using the Cochrane Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Nine RCTs and one nRCT met our inclusion criteria. Fire needle was more effective than medial branch block in terms of visual analogue scale (VAS) after 1 month (p=0.02). Also, Fire needle was more effective than Ibuprofen in terms of VAS and oswestry disability index (ODI) (p<0.05). However, in the rest of the study results, the intervention group did not show a statistically significant difference than the control group. Conclusions Although our review found encouraging but limited evidence of acupuncture for facet joint syndrome, most of the studies included in the analysis were evaluated as methodologically high risk of bias. From now on further well-designed RCTs should be encouraged.

암(癌)에 대한 침치료(鍼治療)의 연구(硏究) 동향(動向) (Study Trends on Acupuncture Treatment of Cancer)

  • 남동우;이재동;최도영
    • Journal of Acupuncture Research
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    • 제24권1호
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    • pp.209-216
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    • 2007
  • Objectives : To review and summarize the existing evidence on acupuncture treatment for cancer and cancer related symptoms. Methods: Literature searches were made through domestic and international databases. Data were extracted according to pre-defined criteria. The methodological quality was assessed using the Modified Jadad scale. Results: Seven studies were included. Two of the studies were high in methodological quality. One study concerning acupuncture treatment for cancerous dyspnea reported insignificant differences between the treatment group and placebo group. The other study concerning auricular acupuncture for cancer related pain showed significant pain relief compared with the control group. All the other studies were non-blinded or uncontrolled trials. Conclusion : The hypothesis that acupuncture may be effective for the treatment of cancer is not supported by the data in recent clinical trials. More accurately designed randomized control trials (RCT) are needed.

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CNKI로 검색한 소아 수두의 한약 내복 치료에 대한 임상연구 동향 - 2000년대 이후 RCT 연구를 중심으로- (Review of Clinical Studies of Oral Herbal Medicine Treatment for Pediatric Chickenpox using CNKI Database - Focused on Chinese Randomized Controlled Trials after 2000s -)

  • 최정윤;김장현;민상연
    • 대한한방소아과학회지
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    • 제34권3호
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    • pp.18-36
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    • 2020
  • Objectives The purpose of this study is to analyze Chinese randomized controlled trials (RCTs), and to evaluate the effectiveness and safety of the oral herbal medicine treatment for pediatric chickenpox. Methods We searched RCTs after 2000s from the China National Knowledge Infrastructure (CNKI). Afterwards, the year of publication, demographic information, duration of chickenpox, intervention, treatment duration, outcome measure, results and adverse events were investigated and analyzed for this study. Results 21 RCTs out of 219 studies were collected and analyzed. Although each composition of the herbal medicine was different, they have common ingredients such as 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風 in order to make efficacy of 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風. The oral herbal medicine showed better efficacy and safety to improve clinical symptoms such as total efficacy, cure rate, antipyretic time, antipruritic time, scab time, anti-rash time, hospitalization period and herpes recovery time compared to the western medicine treatment. Conclusions These results show that the oral herbal medicine treatment on chickenpox in children may be more effective in reducing of clinical symptoms compared to the western medicine treatment.

소아 구내염의 한약치료에 대한 임상연구 동향: 중의학 무작위대조군 임상시험을 중심으로 (A Review of Recent Clinical Studies of Herbal Medicine Treatment for Children's Stomatitis : Focusing on Randomized Controlled Trials in Traditional Chinese Medicine)

  • 허유진;이신희;조연수
    • 대한한방소아과학회지
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    • 제35권4호
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    • pp.125-140
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    • 2021
  • Objectives This study aims to find out the recent trend of the herbal medicine treatment in children's stomatitis in China, and propose better methods to treat children's stomatitis in Korea. Methods The randomized controlled trials (RCT) relevant to 'Herbal medicine treatment on children's stomatitis' were searched using China Academic Journal (CAJ). The search method we used included search formula, (SU = '口內炎' + '口腔炎' + 'stomatitis') and (SU = '儿童' + '小儿' + 'children' + 'child') from 2000 to September 2021. Results A total of 9 RCTs were selected and analyzed. All reports showed that oral administration of herbal medicine were effective and improved clinical symptoms. The most-used herbal medicine category was Heat-clearing medicine (淸熱藥). Conclusions The literatures from China have shown that herbal medicine improves children's stomatitis. These outcomes may be helpful for the treatment of children's stomatitis in Korea. However, further studies are needed to develop treatment guidelines for children's stomatitis.

네트워크 분석을 이용한 불면의 무작위임상시험 해외 연구 동향 (Research Trends of Randomized Clinical Trial for Insomnia Using the Network Analysis)

  • 백영화;진희정
    • 한국콘텐츠학회논문지
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    • 제13권12호
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    • pp.1036-1047
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    • 2013
  • 본 연구는 불면과 관련된 무작위임상시험의 해외 연구 동향을 살펴보기 위하여 시계열적 키워드 비교 분석 및 네트워크 분석을 실시하였다. 분석에 사용된 자료는 'Insomnia'와 'Randomized Clinical Trial'의 연관 키워드를 사용하여 ClinicalTrials의 379건, Web of Science의 132건을 선정하였다. 분석 결과, ClinicalTrials에서는 불면과 약물요법을 중심으로 인지행동요법, 우울 등의 키워드가 네트워크를 이루고 있었다. WOS에서는 ClinicalTrials의 결과에 멜라토닌 키워드가 추가적으로 나타났다. 또한, 연구 대상자 중 특징적으로 노인과 여성에 대한 연구가 꾸준히 진행되는 것으로 파악되었다.

노인 대상 ICT 기반 융합연구: 무작위 대조군 실험연구의 체계적 고찰 (A Systematic Review of Randomized Controlled Trials With ICT-based Convergence Study for the Elderly)

  • 이혜식;박혜연
    • 한국융합학회논문지
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    • 제11권3호
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    • pp.85-93
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    • 2020
  • 본 연구는 노인을 대상으로 한 ICT 기반 융합연구에 대한 국외의 무작위 대조군 실험연구를 체계적으로 고찰하여 ICT 기반 중재의 종류와 효과에 대해 파악하고자 한다. 3개의 데이터베이스와 수기검색으로 확인한 326편 중 선정 기준에 부합하는 8편을 선정하였다. 본 연구결과 가장 많이 사용된 ICT는 인터넷으로 총 3편이었으며, 다음으로 태블릿과 휴대폰이 2편이었고, 그 외에 양방향 화상회의 1편, 키넥트 1편, 로봇 1편, 혈당 관리 시스템 1편이었다. 이러한 연구결과는 국내의 ICT 기반 융합연구에 활용될 수 있을 것이며, 추후 수준 높은 효과 검증을 위해 무작위 대조군 실험 연구와 같은 질적 수준이 높은 연구가 더 많이 진행되어야 함을 보여준다.

불안장애에 대한 침 치료 임상 연구의 체계적 고찰 (A Systematic Review of Clinical Studies on the Effects of Acupuncture on Anxiety Disorders)

  • 김경옥;김천중;서상일;김남열;김근우
    • 동의신경정신과학회지
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    • 제28권3호
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    • pp.249-262
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    • 2017
  • Objectives: The aim of this study was to investigate the clinical studies which focus on acupuncture's effect on anxiety disorder. Methods: We selected clinical studies through six databases. We then examined the characteristics of the selected studies and conducted an assessment for Risk of Bias (ROB). Results: Seventeen randomized-controlled trials were selected to determine the effects of acupuncture on anxiety disorders. We found that the risk of bias in most studies was unclear. The intervention of 7 seventeen randomized-controlled trials (RCT) was basic acupuncture, 8 RCT involved electric acupuncture, 2 RCT consisted of acupuncture and Moxibustion. Four of the 7 basic acupuncture RCTs and 5 of the 8 electric acupuncture RCTs had a significant effect on anxiety factors for anxiety disorders. Conclusions: Acupuncture treatment for anxiety disorders was found to be effective compared to the controls, or there was no difference in effectiveness compared to the controls. However, the quality of the included studies was low, and there only were a small number of studies. Therefore, well-designed studies and a greater number of the studies are needed.

치매의 침치료에 대한 해외 RCT 연구 동향 - pubmed의 2000~2018년 검색을 통하여 - (Recent RCT Research on the Effects of Acupuncture on Dementia - Based on a PubMed Search of Literature Published from 2000 to 2018)

  • 김은지;최기훈;정희경;권오훈;박주헌;김상균
    • 대한한방내과학회지
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    • 제39권3호
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    • pp.338-349
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    • 2018
  • Objective: The purpose of this study is to investigate recent clinical studies on the effects of acupuncture on dementia. Method: We searched RCTs (randomized controlled trials) using the database PubMed (2000-2018). Clinical RCT studies of acupuncture used to treat dementia in humans were included. Nine randomized controlled trials were included. Results: Various acupoints such as Baihui (GV20), Sishencong (EX-HN1), Fengchi (GB20), and Shenting (GV24) were used to treat symptoms. The studies reported a decrease in evaluation criteria, such as the Mini Mental State Examination (MMSE) and activities of daily living (ADL), for measuring cognitive ability. The acupuncture process, the results for outcome measure, and the effectiveness of studies were analyzed. We then assessed "risk of bias." Conclusions: Through this review, we found that acupuncture is applicable for the treatment of dementia. This can be used for future study.

Systematic Review of Chuna Manipulative Treatment for Ankle Sprain

  • Kwak, Min Kyung;Kim, Min Wook;Jeong, Sang Jun;Kim, Shin Ae;Jeong, Mi Young;Kim, Jae Hong
    • Journal of Acupuncture Research
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    • 제35권2호
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    • pp.61-68
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    • 2018
  • Background: This study was performed to review the efficacy of national and international randomized controlled trials (RCT) investigating Chuna manipulative treatment for ankle sprains. Methods: Online databases (PubMed, Cochrane, EMBASE, CNKI, NDSL, OASIS), were searched for studies where Chuna treatment was performed for ankle sprains up to October 12th, 2017. Only RCT were selected that fulfilled the inclusion/exclusion criteria. Data were analyzed using the Cochrane risk of bias tool. Results: There were 676 studies retrieved from the databases, resulting in analysis of 24 RCT. There was an average of 7 treatment visits over a 7 day period and the most frequent evaluation tool used was efficacy rate, with drug therapy being the most common control used in the trials. In 15 RCT, several Chuna methods were used in combination, amongst which, the osteopathic technique was most common. Statistically significant improvement in evaluation indices was reported in 19 RCT, and in 3 RCT, statistically significant improvement was reported, but not for all indices. In the remaining 2 RCT, there were no significant differences in any of the evaluation indices. No adverse reactions were reported in any of the RCT, although it was unknown whether all the trial protocols indicated that adverse reactions should be monitored, and for this reason, the risk of bias was unclear. Conclusion: The review of 24 studies suggest that Chuna manipulative treatment for ankle sprains was effective in most cases, although, potential bias in these studies was difficult to evaluate.

국내 말초성 안면마비의 침 임상시험에 대한 체계적 고찰 (Acupuncture Trials for Peripheral Facial Palsy in Republic of Korea: A Systematic Review)

  • 이참결
    • Journal of Acupuncture Research
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    • 제30권3호
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    • pp.51-59
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    • 2013
  • Objectives : This study was designed to evaluate clinical evidence of acupuncture treatment for peripheral facial palsy in South Korea. Methods : All process was independently proceeded by two investigators. Literature search was performed in 9 databases from their inception to February 2013. Searched reports was twice excluded for title, abstract and body. And then, data extract and analysis was done before assessing risk of bias by Cochrane Handbook. Results : 10 randomized controlled trials(RCT) were finally included. 4 RCT handled postauricular pain with facial palsy. All articles at least used in combination with two treatments. Interventions like pharmacopuncture, electroacupuncture, scalp acupuncture etcetera were conducted as treatment to evaluate efficacy, and some study reported advantageous effects of treatment group compared to baseline or control group. Adverse events didn't referd to in any studies. In assessing risk of bias, indefinite and uncertain information made all included trials to have a high risk of bias. Conclusions : Because of methodological deficit, there is no sufficient evidence to allow any conclusion about the efficacy of acupuncture for peripheral facial palsy. Therefore, well designed trials with high quality is needed from now on.