• Title/Summary/Keyword: R123

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From R&D to Commercialization : A System Dynamic Approach

  • Choi, Kang-Hwa;Kim, Soo-W.
    • International Journal of Quality Innovation
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    • v.9 no.3
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    • pp.123-144
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    • 2008
  • This paper describes a comprehensive approach to examine how technological innovation contributes to the renewal of a firm's competences through its dynamic and reciprocal relationship with R&D and product commercialization. Three theories of technology and innovation (the R&D and technological knowledge concept, product-process concept, technological interdependence concept) are used to relate technology and innovation to strategic management. Based on these theories, this paper attempts to identify the dynamic relationship between product innovation and process innovation using system dynamics by investigating that aspect of the dynamic changes in the closed feedback circulation structure in which R&D investments drive the accumulation of technological knowledge. Further, such knowledge accumulation actualizes product innovation and process innovation, subsequently resulting in an increase in productivity, customer satisfaction, profit generation, and.

Evaluation of Material Properties Considering Thermal Embrittlement for Accelerated aged CF-8M and CF-8A Cast Austenitic Stainless Steel (가속열화된 CF-8M 및 CF-8A 주조 스테인리스강의 열취화 재료물성치 평가)

  • Kim, Cheol;Park, Heung-Bae;Jin, Tae-Eun;Jeong, Ill-Seok
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.118-123
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    • 2004
  • Cast austenitic stainless steel have been widely used for primary coolant piping in light water reactors. This material is subject to thermal embrittlement at reactor operating temperature. CF-8M and CF-8A cast austenitic stainless steel is used for several components, such as primary coolant piping, elbow, pump casing, and valve bodies in light water reactors. Thermal embrittlement results in spinodal decomposition of delta-ferrite leading to decreased fracture toughness. In this study, the specimens were prepared using an accelerated aging method. The measurement of ferrite content, Charpy impact test and J-R test were performed to verify the predicting equation for aged material properties. In case of above 25% ferrite content, predicted result of J-R curve might be non-conservative.

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Adhesion Behaviors of Semiconductive-Insulation Interfaced Liquid Silicone Rubber for EHV Cable Accessory (초고압 접속재용 반도전-절연체 액상실리콘 계면의 접착거동)

  • Yoon, Seung-Hoon;Kim, Hyun-Seok;Kim, Ji-Hwan;Lee, Jung-Hee
    • Proceedings of the KIEE Conference
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    • 2003.10a
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    • pp.123-127
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    • 2003
  • 액상실리콘으로 이루어진 초고압전력케이블용 프리몰드 접속재의 반도전-절연체 계면접합체를 다양한 제조조건과 조합별로 제조하여 계면접착력에 대한 영향을 검토하였다. 후가교적용 시 계면접착력이 강화되며 grade조합에 따른 특성차이가 존재하였다. 하지만 고온 장시간의 후가교 조건에서는 계면간의 화학적 결합력의 저하로 인해 오히려 접착력이 낮아지기도 하였다. 절연 RTV와의 계면접착성은 S-1재료가, 절연 LSR의 경우에는 S-3 재료가 가장 우수하였으며 도전안정성 측면에서도 S-3 재료가 상대적으로 유리하였다. 매입형 전극체를 제조하여 절연파괴거동을 연구한 결과 계면접착성과의 직접적인 상관관계는 크지 않음을 알 수 있었다.

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The Separation of Time and Space Tree for Moving or Static Objects in Limited Region (제한된 영역에서의 이동 및 고정 객체를 위한 시공간 분할 트리)

  • Yoon Jong-sun;Park Hyun-ju
    • Journal of Information Technology Applications and Management
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    • v.12 no.1
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    • pp.111-123
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    • 2005
  • Many indexing methods were proposed so that process moving object efficiently. Among them, indexing methods like the 3D R-tree treat temporal and spatial domain as the same. Actually, however. both domain had better process separately because of difference in character and unit. Especially in this paper we deal with limited region such as indoor environment since spatial domain is limited but temporal domain is grown. In this paper we present a novel indexing structure, namely STS-tree(Separation of Time and Space tree). based on limited region. STS-tree is a hybrid tree structure which consists of R-tree and one-dimensional TB-tree. The R-tree component indexes static object and spatial information such as topography of the space. The TB-tree component indexes moving object and temporal information.

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STUDY ON THE STABILITY OF O/W AND MLV EMULSION CONTAINING DIHYDROXYACETONE

  • Joo, Yong-Joon;Han, Yeoung-Jun;Joo, Yong-Ho;Jeon, Young-Hwan
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.3
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    • pp.123-128
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    • 1998
  • Dihydroxyacetone (DHA) has been used as a self tanning agent and many emulsion formulations containing DHA have been studied. In an emulsion, many factors which have negative effect on DHP and the resultant DHA decomposition can destabilize the emulsion base. In this study, two kinds of emulsion with 5% DHA were prepared, O/W type emulsion and Multilamellavesicle (MLV) type emulsion to compare the stabilization effects of both emulsions on the DHA. The OHA concentration was analyzed quantitatively by high performance liquid Chromatography (HPLC), also the pH and viscosity of both emulsions were measured for stability. This process was carried out over 4 months. For HPLC, a bondaclone $C_{18}$ column with a mobile phase of distilled water and UV detector were used. The results of these experiment showed that DHA is more stable in an MLV emulsion than it is in an O/W type emulsion.

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Design of the Ultrasonic Motor for Driving Robot Hand (로봇 손 구동용 초음파 모터의 설계)

  • Park, K.J.;Baek, S.H.;Kim, S.H.;Jung, H.K.;Chung, I.R.;Chang, H.S.
    • Proceedings of the KIEE Conference
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    • 1999.07a
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    • pp.121-123
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    • 1999
  • The purpose of this paper is to establish a method of design of the Ultrasonic Motor for Driving Robot Hand. This method is based on two models for the ultrasonic motor(a two dimensional elastic contact model. electric equivalent circuit). And analyzed the basic model which installed in the module to match the suitable standard. As varied external diameter, internal diameter and thickness, the proper ultrasonic motor is implemented to find a targeted resonant-frequency and torque near to designed values.

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Activation of acetylcholine receptor elicits intracellular Ca2+ mobilization, transient cytotoxicity, and induction of RANKL expression

  • Heo, Seong-Jong;Kim, Min Seuk
    • International Journal of Oral Biology
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    • v.41 no.3
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    • pp.119-123
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    • 2016
  • Acetylcholine receptors (AChR) including muscarinic and nicotinic AChR are widely expressed and mediate a variety of physiological cellular responses in neuronal and non-neuronal cells. Notably, a functional cholinergic system exists in oral epithelial cells, and nicotinic AChR (nAChR) mediates cholinergic anti-inflammatory responses. However, the pathophysiological roles of AChR in periodontitis are unclear. Here, we show that activation of AChR elicits increased cytosolic $Ca^{2+}([Ca^{2+}]_i)$, transient cytotoxicity, and induction of receptor activator of nuclear factor kappa-B ligand (RANKL) expression. Intracellular $Ca^{2+}$ mobilization in human gingival fibroblast-1 (hGF-1) cells was measured using the fluorescent $Ca^{2+}$ indicator, fura-2/AM. Cytotoxicity and induction of gene expression were evaluated by measuring the release of glucose-6-phosphate dehydrogenase and RT-PCR. Activation of AChR in hGF-1 cells by carbachol (Cch) induced $[Ca^{2+}]_i$ increase in a dose-dependent manner. Treatment with a high concentration of Cch on hGF-1 cells caused transient cytotoxicity. Notably, treatment of hGF-1 cells with Cch resulted in upregulated RANKL expression. The findings may indicate potential roles of AChR in gingival fibroblast cells in bone remodeling.

Estimation of Thermodynamic Properties of Refrigerant Mixtures Using a Modified Carnaha-Starling Equation of State (수정된 Carnahan-Starling 상태방정식을 이용한 혼합냉매의 물성계산)

  • 김민수;김동섭;노승탁
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.15 no.6
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    • pp.2189-2205
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    • 1991
  • Thermodynamic properties of binary nonazeotropic refrigerant mixtures are estimated by using a modified Carnhan-Starling equation of state. In this study, pure component refrigerants such as R14, R23, R13, R13 B1, R22, R12, R134a, R152a, R142b, RC318, R114, R11, R123 and R113 are chosen and the thermodynamic properties of enthalpy and entropy are calculated in terms of relevant variables. The modified Carnahan-Starling equation of state is compared with the carnahan-Staring-De Santis equation of sate. Results show that the relative errors become slightly smaller with the equation of state proposed in this study. Correlations are obtained for the mixtures of which the vapor liquid equilibruim data are available to us in the literature. Those mixtures are R14/R23, R23/R12, R13/R12, R13/R11, R13B1/R22, R13B1/RC318, R12/RC138, R12/R114 and R12/R11. The binary interaction coefficients are found under the condition of minimizing the pressure deviations at the vapor liquid equiblibrium state and the estimation of the vapor liquid equilibrium for the refrigerant mixtures is done. Pressure-enthalpy and temperature-entropy diagrams are plotted for the refrigerant mixtures of specific composition.

Characterization of Vibrio harveyi, the Causal Agent of Vibriosis in Cultured Marine Fishes in Korea

  • Won, Kyoung-Mi;Kim, Su-Mi;Park, Soo-Il
    • Fisheries and Aquatic Sciences
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    • v.9 no.3
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    • pp.123-128
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    • 2006
  • An epizootic causing mortality among cultured marine finfishes occurred in 1999 in the province of Kyoungsang, Korea. The disease was characterized by the presence of enterocele, abdominal swelling, and gastroenteritis. The causative bacteria were isolated from olive flounder (Paralichthys olivaceus), black rockfish (Sebastes schlegeli), turbot (Scophthalmus maximus) and the rearing water. These bacteria showed swarming activity on agar plates and yellowish or greenish colonies on thiosulfate-citrate-bile salts-sucrose (TCBS) agar plates, but no luminescence. The pathogen was identified as Vibrio harveyi based on morphological and biochemical characteristics and the sequence of l6S rDNA. The lethal doses (LD$_{50}$) of olive flounder and black rockfish were estimated to be $1.24\times10^6-1.36\times10^8$ and $3.24\times10^5-5.8\times10^7$ CFU/fish respectively following intraperitoneal injection.

Diagnostic Assay of Toxic Zinc in an Ex Vivo Cell Using Voltammetry

  • Ly, Suw-Young;Yoo, Hai-Soo
    • Toxicological Research
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    • v.28 no.2
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    • pp.123-127
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    • 2012
  • Voltammetric detection of the toxic Zn ion was investigated using a fluorine-doped graphite pencil electrode (FPE). It is notable from the study that pencils were used as reference and working electrodes. In all the experiments, a clean seawater electrolyte solution was used to yield good results. The analytical working range was attained to 10 ${\mu}gL^{-1}$. The optimized voltammetric condition was examined to maximize the effect of the detection of trace Zn. The developed sensor was applied to an earthworm's tissue cell. It was found that the methods can be applicable to in vivo fluid or agriculture soil and plant science.