STUDY ON THE STABILITY OF O/W AND MLV EMULSION CONTAINING DIHYDROXYACETONE

  • Published : 1998.09.01

Abstract

Dihydroxyacetone (DHA) has been used as a self tanning agent and many emulsion formulations containing DHA have been studied. In an emulsion, many factors which have negative effect on DHP and the resultant DHA decomposition can destabilize the emulsion base. In this study, two kinds of emulsion with 5% DHA were prepared, O/W type emulsion and Multilamellavesicle (MLV) type emulsion to compare the stabilization effects of both emulsions on the DHA. The OHA concentration was analyzed quantitatively by high performance liquid Chromatography (HPLC), also the pH and viscosity of both emulsions were measured for stability. This process was carried out over 4 months. For HPLC, a bondaclone $C_{18}$ column with a mobile phase of distilled water and UV detector were used. The results of these experiment showed that DHA is more stable in an MLV emulsion than it is in an O/W type emulsion.

Keywords

References

  1. Cosm & Toil v.91 V Usdin
  2. Cosm & Toil v.109 T Kurz
  3. Cosm & Toil v.98 M Rieger
  4. Parfumerie und Kosmetik 77 550 T Kurz
  5. Farmaco 38 415 Bobin M
  6. J. of the Society of Cosmetic Chemists v.163 Goldman L
  7. Food Res. v.25 HG Lento
  8. Ind. Eng. Chem. Res. v.6
  9. Farmaco 38 403 Bobin M
  10. Farmaco 36 424 Baruffini A
  11. Cosm & Toil v.106 Hans E
  12. Pharmaceutical Manufacturing v.2 no.8 Eric M