• Title/Summary/Keyword: R&D activities

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Value Chain and Networks of Foreign Direct Investment Firms in Transitional Economies: Korean Textile and Clothing Foreign Direct Investment in Vietnam (전환경제하의 해외직접투자기업의 가치사슬과 네트워크: 대베트남 한국 섬유.의류산업 해외직접투자 사례 연구)

  • Lee, Sung-Cheol
    • Journal of the Economic Geographical Society of Korea
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    • v.10 no.2
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    • pp.93-115
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    • 2007
  • As strategies for creating profits are differentiated by the national economic system and development strategies related to firms' geographical scope, they depend on the spatial contexts and product characteristics. In this perspective, strategies for the profit creation of Korean textile and clothing FDI firms invested in Vietnam has involved in the geographical differentiations in accordance with the development path of transitional economies, changes in institutional environments and the characteristics of products. Therefore. the main purpose of this research is to identify the way in which they have their own identity in transitional economies by investigating business pattern, commodity chain and extra-firm relations, which are related to institutional dynamics in Vietnam. There are two main characteristics of Korean textile and clothing FDI firms in Vietnam. The first is that all business activities involved in the commodity chain of them from R&D to production is controlled by global retailer and distributors, which is the buyer-driven commodity chain and the typical commodity chain of the textile and clothing industry. The second could be defined as over- or unforced embeddedness into the institutional legacy of the Soviet system, because they have been incorporated into pre-existing networks based on reciprocal relations in Vietnam.

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Spreading and Distribution of Lactuca scariola, Invasive Alien Plant, by Habitat Types in Korea (침입외래식물 가시상추의 확산과 생육지 유형별 분포 특성)

  • Kim, Young-Ha;Kil, Ji-Hyon;Hwang, Sun-Min;Lee, Chang-Woo
    • Weed & Turfgrass Science
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    • v.2 no.2
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    • pp.138-151
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    • 2013
  • This study was carried out to investigate the distribution and habitat types of prickly lettuce, Lactuca scariola of Europe origin for supplying the basic data of management plan. It showed fairly nation-wide distribution although excessive growth was rather limited in the wild. Its habitat types were divided into four types like open fields, roadsides, seashores and riversides. Species diversity examined by species rank-dominance curve tended to increase over riverside > seashores > open fields > roadsides. As a result of analyzing life form, therophytes were more than 50%, means that the habitats of L. scariola were disturbed by human activities etc. Urbanization Index was analyzed 9.1% in roadsides, 7.4% in seashores, 5.8% in open fields and riversides. It has high spread potential with a large number of wind-flying seed per plant. It was evaluated that prickly lettuce was mainly spread along the newly constructed road, expressway and invaded the original ecosystem in the cultivated land as weeds. But it has played a role as a pioneer species in open fields. It is recommended to remove where it has considerable impact on the native plant species of conservation value.

Quality characteristics and antioxidant capacities of Korean commercial yogurt (시판 호상 요구르트의 품질 특성과 항산화 활성)

  • Noh, Young-Hee;Jang, Ah-Soon;Pyo, Young-Hee
    • Korean Journal of Food Science and Technology
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    • v.52 no.2
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    • pp.113-118
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    • 2020
  • We investigated the quality characteristics and antioxidant capacities of Korean commercial yogurt. Twenty commercial yogurt samples exhibited a pH of 4.05-4.51, titratable acidity of 0.80-1.45%, viable counts of 6.65-9.39 log CFU/g, and total phenolic content of 0.71-2.92 mg gallic acid equivalent/g dry weight (dw). Lactic acid was the major organic acid detected by HPLC with UV detection, and its content was 5.4 times and 46.5 times higher than that of malic acid and citric acid, respectively. The tested commercial yogurt samples exhibited antioxidant potential (1.62-8.95 mM trolox equivalent/g, dw) measured based on scavenging activities of DPPH and ABTS radicals. The average antioxidant potentials of commercial set yogurt containing fruit syrup were significantly (p<0.05) higher than that of cream and plain yogurt. A positive linear correlation was observed between the total phenolic content and the antioxidant capacities, suggesting that phenolic components are likely to contribute significantly to the antioxidant potential of commercial yogurt.

Inhibitory Effect on the Growth of Intestinal Pathogenic Bacteria by Kimchi Fermentation (김치 발효에 의한 장내병원균의 생육저해효과)

  • Kang, Chang-Hoon;Chung, Kyung-Oan;Ha, Duk-Mo
    • Korean Journal of Food Science and Technology
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    • v.34 no.3
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    • pp.480-486
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    • 2002
  • Six strains of intestinal pathogenic bacteria were inoculated into kimchi at the preparation time, and the influence of kimchi fermentation on the growth of these pathogenic bacteria was investigated. The population of coliform bacteria in the kimchi raw materials, and its changes in the kimchi sample during fermentation were also determined. Among the raw materials, highest populations of coliform bacteria were detected in ginger and green onion, followed by Chinese cabbage, red pepper, and garlic. Populations of pathogenic bacteria (inoculated strains) and coliform bacteria in kimchi decreased as pH decreased with fermentation. Coliform bacteria disappeared at pH 3.9 in Chinese cabbage kimchi samples. Clostridium perfringens ATCC 13124, Listeria monocytogenes ATCC 19111, Salmonella typhimurium KCTC 1625, Staphylococcus aureus KCTC 1621, Vibrio parahamolyticus ATCC 27519, and Escherichia coli O157 H:7 ATCC 43894 were not detected at pH values less than 4.1, 3.7, 3.8, 3.8, 3.7, and 3.7 in Chinese cabbage kimchi, and at pH values less than 4.5, 4.0, 4.2, 4.2, 4.2 and 4.1 in mustard leaf kimchi, respectively. The juice of mustard leaf and allyl isothiocyanate exhibited high antimicrobial activities on the pathogenic bacteria, whereas the lowest on lactic acid bacteria. These results indicated that fermentation is useful to improve the safety of kimchi, and the antimicrobial effect of mustard leaf kimchi is mainly due to the major pungent compound of mustard leaf, allyl isothiocyanate.

Monitoring on Extraction Conditions for Physicochemical Qualities of Ethanol Extract from Garlic (마늘 에탄올 추출물의 이화학적 특성에 대한 추출조건의 모니터링)

  • Cha, Tae-Yang;Kim, Seong-Ho;Kwon, Taeg-Kyu;Kwon, Joong-Ho;Lee, Sang-Han;Lee, Jin-Man
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.9
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    • pp.1198-1204
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    • 2007
  • This study was carried out to find the optimal conditions for the extraction of the effective ingredients based on central composite by monitoring the extraction characteristics of each ingredient with a response surface methodology. The optimal condition for the effective component alliin was extract temperature of $60.86^{\circ}C$, extract time of 3.77 hr, and ethanol concentration of 50.68%, and that for allicin was $65.11^{\circ}C$, 2.79 hr, and 13.62%, respectively, with the maximum extraction of 16.72 mg%. The maximum value of extracted total phenolics was 16.72 mg%, the optimal condition for electron donating ability was $93.35^{\circ}C$, 3.22 hr and 10.38%. The optimal conditions for pH 1.2 and 3.0 nitrite-scavenging ability was extract temperature of $79.77^{\circ}C$ and $76.46^{\circ}C$, extract time of 3.22 hr and 3.31 hr, and the ethanol concentration of 10.38% and 1.12%, respectively. With this optimal condition, the obtained maximum values for nitrite-scavenging activities at pH 1.2 and 3.0 were 94.85% and 63.22%, respectively.

Ag-Loaded LaSrCoFeO3 Perovskite Nano-Fibrous Web for Effective Soot Oxidation (Ag 담지된 LaSrCoFeO3 섬유상 perovskite 촉매의 탄소 입자상 물질의 산화반응)

  • Lee, Chanmin;Jeon, Yukwon;Hwang, Ho Jung;Ji, Yunseong;Kwon, Ohchan;Jeon, Ok Sung;Shul, Yong-Gun
    • Korean Chemical Engineering Research
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    • v.57 no.4
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    • pp.584-588
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    • 2019
  • The catalytic combustion of particulate matter (PM) is one of the key technologies to meet emission standards of diesel engine system. Therefore, we herein suggest Ag loaded $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_3$ perovskite web catalyst. They were produced by the electrospinning method. FE-SEM, EDS mapping, XRD, XPS were studied to investigate the crystal and morphological structures of loaded Ag particles and $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_3$ perovskite web catalyst. Following the catalytic soot oxidation, we found that the Ag loaded $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_3$ perovskiteweb catalyst showed the higher catalytic activities (e.g., $T_{50}=490^{\circ}C$) than the only $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_3$ perovskite web catalyst (e.g., $T_{50}=586^{\circ}C$). Thus, this finding suggests that Ag loaded $La_{0.6}Sr_{0.4}Co_{0.2}Fe_{0.8}O_3$ perovskite web catalyst can be a promising candidate for enhancing the soot oxidation.

Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model

  • Shin, Phil-Kyung;Zoh, Yoonchae;Choi, Jina;Kim, Myung-Sunny;Kim, Yuri;Choi, Sang-Woon
    • Nutrition Research and Practice
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    • v.13 no.1
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    • pp.58-63
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    • 2019
  • BACKGROUND/OBJECTIVES: Telomeres are located at the chromosomal ends and progressively shortened during each cell cycle. Telomerase, which is regulated by hTERT and c-MYC, maintains telomeric DNA sequences. Especially, telomerase is active in cancer and stem cells to maintain telomere length for replicative immortality. Recently we reported that walnut phenolic extract (WPE) can reduce cell viability in a colon cancer stem cell (CSC) model. We, therefore, investigated the effect of WPE on telomere maintenance in the same model. MATERIALS AND METHODS: $CD133^+CD44^+$ cells from HCT116, a human colon cancer cell line, were sorted by Fluorescence-activated cell sorting (FACS) and treated with WPE at the concentrations of 0, 10, 20, and $40{\mu}g/mL$ for 6 days. Telomere lengths were assessed by quantitative real-time PCR (qRT-PCR) using telomere specific primers and DNA extracted from the cells, which was further adjusted with single-copy gene and reference DNA ($ddC_t$). Telomerase activity was also measured by qRT-PCR after incubating the PCR mixture with cell protein extracts, which was adjusted with reference DNA ($dC_t$). Transcriptions of hTERT and c-MYC were determined using conventional RT-PCR. RESULTS: Telomere length of WPE-treated cells was significantly decreased in a dose-dependent manner ($5.16{\pm}0.13$ at $0{\mu}g/mL$, $4.79{\pm}0.12$ at $10{\mu}g/mL$, $3.24{\pm}0.08$ at $20{\mu}g/mL$ and $3.99{\pm}0.09$ at $40{\mu}g/mL$; P = 0.0276). Telomerase activities concurrently decreased with telomere length ($1.47{\pm}0.04$, $1.09{\pm}0.01$, $0.76{\pm}0.08$, and $0.88{\pm}0.06$; P = 0.0067). There was a positive correlation between telomere length and telomerase activity (r = 0.9090; P < 0.0001). Transcriptions of both hTERT and c-MYC were also significantly decreased in the same manner. CONCLUSION: In the present cell culture model, WPE reduced telomere maintenance, which may provide a mechanistic link to the effect of walnuts on the viability of colon CSCs.

Derivation of Anti-Tamper System Requirements Based on CMVP Standard for Technology Protection of Weapon Systems (무기 시스템의 기술 보호를 위한 CMVP 표준 기반의 Anti-Tamper 시스템 요구사항 도출)

  • Lee, Min-Woo;Lee, Jae-Chon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.4
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    • pp.470-478
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    • 2019
  • As the growth of the domestic defense industry is remarkable regarding technology level and export size, technology protection is necessary. Particularly, there is a need to apply anti-tamper measures to prevent critical technologies from illegally being taken out of weapon systems. However, there is no security protection strategy and system built yet in ROK. Precedent studies discussed the trend analysis and technical research for specific protective techniques, and the application of anti-tamper using limited procedures was provided. Recently, methods of how to select the technology for protection were studied based on risk management. Nonetheless, these studies cannot be associated with the acquisition process for the whole life-cycle, having difficulty with actual development and evaluation of the weapon systems. The objective of our study is to derive the system requirements of the weapon system for which anti-tamper measures have been determined to apply. Specifically, requirements items suitable for the development of anti-tamper weapon systems were derived based on ISO/IEC 19790, the CMVP standard for the development and verification of cryptographic modules. Also, its utilization in technical reviews and test & evaluations was presented. The usefulness of the research results was confirmed through inductive inference and comparative evaluation. The result can be expected to play a role in initiating extensive activities needed for technology protection of the weapon systems.

A Study on Health Risk Assessment by Exposure to Organic Compounds in University Laboratory (대학 실험실에서의 유기화합물 노출에 의한 건강위험성 평가에 관한 연구)

  • Sim, Sanghyo;Won, Jung-II;Jeon, Hasub;Kim, Dowon
    • The Journal of Korean Society for School & Community Health Education
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    • v.22 no.4
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    • pp.49-60
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    • 2021
  • Objectives: Laboratories have various latent physical, chemical, biological, and ergonomical factors according to the diversification and fusion of research and development activities. This study aims to investigate the chemical exposure concentrations of college laboratories and evaluate their health risks, and use them as basic data to promote the health of college students. Methods: The sampling and analysis of harmful chemicals in the air in laboratories were performed using Method 1500 of the U.S. National Institute for Occupational Safety and Health (NIOSH)의 Method 1500. The harmful chemicals in the laboratories were divided into carcinogenic and non-carcinogenic chemicals. Risk assessment was performed using the cancer risk (CR) for carcinogenic chemicals and using the hazard index (HI) for non-carcinogenic chemicals. Results: The harmful chemicals in college laboratories consisted of acetone, diethyl ether, methylene chloride, n-hexane, ethyl acetate, chloroform, tetrahydrofuran, toluene, and xylenes. They showed the highest concentrations in laboratories A (acetone 0.001~2.34ppm), B (chloroform 0.95~6.35ppm), C (diethyl ether 0.08~8.68ppm), and D (acetone 0.07~14.96ppm). The risk assessment result for non-carcinogenic chemicals showed that the HI of methylene chloride was 2.052 for men and 2.333 for women, the HI of N-hexane was 4.442 for men and 5.05 for women. Thus, the HI values were higher than 1. The risk of carcinogenic chemicals is determined by an excess cancer risk (ECR) value of 1.0×10-5, which means that one in 100,000 people has a cancer risk. The ECRs of chloroform exceeded 1.0×10-5 for both men and women, indicating the possibility of cancer risk. Conclusion: College laboratories showed the possibility of non-carcinogenic health risks for methylene chloride, n-hexane, tetrahydrofuran (THF), toluene, and xylenes, and carcinogenic health risks for chloroform, methylene chloride. However, this study used the maximum values of measurements to determine the worst case, and assumed that the subjects were exposed to the corresponding concentrations continuously for 8 hours per day for 300 days per year. In consideration of the nature of laboratory environment in which people are intermittently exposed, rather than continuously, to the chemicals, the results of this study has an element of overestimation.

Enhancement of Immune Activities of Fermented Morinda citrifolia L. (Noni) and Six Marker Compounds (노니 지표성분 6종과 발효노니의 면역활성 증진 효과)

  • Choi, Sun-Il;Han, Xionggao;Men, Xiao;Lee, Se-Jeong;Kim, Yong Deok;La, Im-Joung;Seong, Geum-Su;Lee, Ok-Hwan
    • Journal of Food Hygiene and Safety
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    • v.37 no.1
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    • pp.29-37
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    • 2022
  • This study will evaluate the effect of fermented Morinda citrifolia L. extracts and its marker compounds to provide baseline data for utilizing Morinda citrifolia L. as functional health products. Morinda citrifolia L. and six marker compounds were processed on RAW 246.7 macrophage to test for XTT Cytotoxicity, measure Nitric Oxide and Cyokine formation, and analyze the expression of immune marker genes. Furthermore, LPS and fermented red ginseng extract, a common functional ingredient, are used as positive controls. Our results showed that fermented Morinda citrifolia L and six bioactive compounds did not have any cytotoxic effect in all treatment concentrations and groups. Among six bioactive compounds, SCP and ASE confirmed the formation of NO. In addition, the ASE treatment group showed increased formation of IL-6 and IL-1β and the expression of iNOS and TNF-α. Also, fermented Morinda citrifolia L extract activated the macrophage by enhancing the production of nitric oxide (NO), interleukin (IL)-6, and IL-1β, and the expression of COX2 compared to Morinda citrifolia L. extracts. The result of the study showed that Fermented Morinda citrifolia L. (Noni) and marker compound enhance the innate immunity activity and suggested that the bioactive compound could be applied as a marker compound. Thus, Fermented Morinda citrifolia L. (Noni) could be used as functional food material to develop immunity-enhancing products, and highly functional marker compounds can be utilized as the effective components.