• Toxicological Research
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• v.34 no.4
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• pp.303-310
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• 2018

The methods of applied genetic toxicology are changing from qualitative hazard identification to quantitative risk assessment. Recently, quantitative analysis with point of departure (PoD) metrics and benchmark dose (BMD) modeling have been applied to in vitro genotoxicity data. Two software packages are commonly used for BMD analysis. In previous studies, we performed quantitative dose-response analysis by using the PROAST software to quantitatively evaluate the mutagenicity of four piperidine nitroxides with various substituent groups on the 4-position of the piperidine ring and six cigarette whole smoke solutions (WSSs) prepared by bubbling machine-generated whole smoke. In the present study, we reanalyzed the obtained genotoxicity data by using the EPA's BMD software (BMDS) to evaluate the inter-platform quantitative agreement of the estimates of genotoxic potency. We calculated the BMDs for 10%, 50%, and 100% (i.e., a two-fold increase), and 200% increases over the concurrent vehicle controls to achieve better discrimination of the dose-responses, along with their BMDLs (the lower 95% confidence interval of the BMD) and BMDUs (the upper 95% confidence interval of the BMD). The BMD values and rankings estimated in this study by using the EPA's BMDS were reasonably similar to those calculated in our previous studies by using PROAST. These results indicated that both software packages were suitable for dose-response analysis using the mouse lymphoma assay and that the BMD modeling results from these software packages produced comparable rank orders of the mutagenic potency.

• Natural Product Sciences
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• v.17 no.4
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• pp.321-327
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• 2011

In this study, quantitative analysis was developed using HPLC/UVD for the quality evaluation of Scutellariae Radix. For quantitative analysis, six major bioactive compounds were assessed. The separation conditions employed for HPLC/UVD were optimized using Phenomenex $C_{18}$ column ($250{\times}4.6$ mm, 5 ${\mu}m$) with a gradient of solvent A (1% acetic acid of $H_2O$) and solvent B (acetonitrile : methanol : acetic acid = 70 : 30 : 1) as the mobile phase at a flow rate of 1.0 mL/min and a detection wavelength of 275 nm. These methods were fully validated with respect to linearity, accuracy, precision and recovery. The HPLC/UVD method was applied successfully to the quantification of six major compounds in the extract of Scutellariae Radix. The results indicate that the established HPLC/UVD method is suitable for the quantitative analysis and quality control of multicomponents in Scutellariae Radix.

• Environmental Analysis Health and Toxicology
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• v.4 no.1_2
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• pp.11-17
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• 1989

A quantitative analytical method of highly concentrated PCB is established in the research. With the quantitative analytical method PCB of insulating oil was examined. The following conclusions are derived from this research. 1. The recovery ratio was 95.7% with the quantitative analytical method, which indicates it can be used for the analysis of PCB. 2. PCB concentration of insulation oil in waste condenser was found to be 21.2% thru 13.85% , which was highly concentrated. 3. PCB insulation oil in waste condenser was same as PCB-42.

• KIPS Transactions on Software and Data Engineering
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• v.1 no.2
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• pp.75-80
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• 2012

There are many problems that cause the process improvement of software and hardware, personality errors during software development. This paper propose the quantitative analysis of error that removes and manages the system problems as well.

• Speech Sciences
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• v.7 no.3
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• pp.139-149
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• 2000

Studying language by the quantitative linguistic method is not a recent development. Lately however, the interest in the quantitative linguistics has increased according to the demand on communication between human and human or between human and machine. We are required to transfer the system of the natural language onto machine. This requires the study of quantitative linguistics because we are unable to seize the characters of the tiny linguistic units and their structure in an intuitive way. In fact, the quantitative linguistics treats the internal structure of the language by the relation between the linguitic units and their quantitative characters. It is natural then that there is this growing interest in quantitative linguistics. In addition, Korean linguists take interest in the quantitative linguistics, although quantitative linguistics in Korea is not advanced by the level of the statistical analysis. Therefore, this present study shows how statistics can be applied in the field of linguistics through the two texts written in French: Lovers of the Subway and Our life's A. B. C.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.11
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• pp.1943-1947
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• 2016

Korea Electrical Safety Cooperation(KESCO) have provided the electrical safety speed-call service from 2007 year. Purpose of the service is to reduce discomfort of electricity use and to prevent electrical accident like as electrical fire and shock accident by providing emergency treatment service on fault of the residential electrical facilities notified in the specific house like as a lower-income group and a social welfare facility. But efficiency and economic evaluation of the electrical safety speed-call service is impossible because analysis on the quantitative effect of the service is difficult. This paper presents cost-benefit analysis method and result of the electrical safety speed-call service. The presented cost-benefit analysis method has a two-step process: the first step is to measure quantitative electrical fire prevention effect of the service by using electrical accident statistics and developing outcome analysis logic model of the service effect, and the second step is to analysis cost-benefit(B/C)of the service by calculating quantitative benefit analysis on the measured quantitative electrical fire prevention effect. The results showed that cost-benefit(B/C)of the electrical safety speed-call service is over 4 after 2010 year.

• Food Science and Biotechnology
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• v.18 no.2
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• pp.279-293
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• 2009

Quantitative risk assessments are related to implementing hazard analysis and critical control points (HACCP) by its potential involvement in identifying critical control points (CCPs), validating critical limits at a CCP, enabling rational designs of new processes, and products to meet required level of safety, and evaluating processing operations for verification procedures. The quantitative risk assessment is becoming a standard research tool which provides useful predictions and analyses on microbial risks and, thus, a valuable aid in implementing a HACCP system. This paper provides a review of microbial modeling in quantitative risk assessments, which can be applied to HACCP systems.

• Korean Institute of Interior Design Journal
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• no.8
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• pp.32-38
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• 1996

The main focus of this paper is to apply contemporary aesthetics and psychological study with interior design analysis. Up to now, the methodology of interior design analysis has been developed toward a more qualitative way. By the virtue of the perception , congnition , and information theory, which oriented toward a quantitative approach, it became possible to investigate interior space analysis to a more objective and scientific ways. The purpose of this study is to investigate Modern and Post-Modern interior - architectural style with quantitative analytical method. The subjective interior critique studied by intuitive research will be transferred to scientific way by using quantitative formula . Savoye Villa and Guardiola House were selected as study model, because each architectural works ware regarded as masterpieces of Modern and Post-Modern style. These two oppositional style model will be distinguished with mathematical quantity by calculating Iave , Hmax, and Redundancy formula.

• Journal of the Korean Magnetic Resonance Society
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• v.24 no.1
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• pp.30-37
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• 2020

Quantitative nuclear magnetic resonance (qNMR) has been gaining attention as a purity assessment method. In particular, qNMR is recognized as the primary method to realize the Internal System of Units (SI) in organic analysis. The capability of quantitative analysis is recognized as the beginning of NMR development. NMR signals are proportional to the number of nuclei and qNMR has been used in various fields, such as metabolomics and food and pharmaceutical analysis. However, careful sample preparation and thorough optimization of measurement parameters are required to obtain accurate and reliable results. In this review, quantitative methods used in qNMR are discussed, and the important factors to be considered also introduced. The recent development of qNMR techniques including combination with chromatography and, multidimensional NMR are also presented.

• Journal of the Korean Society for Nondestructive Testing
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• v.22 no.6
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• pp.643-648
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• 2002

In this study, shearography and ESPI have been used for quantitative analysis of an inside crack of pipeline and both of them appeared suitable to qualitatively detect inside crack. However, shearography needs several effective factors including the amount of shearing, shearing direction and induced load for the quantitative evaluation of the inside crack. In this study, the factors were optimized for the quantitative analysis and the site of cracks has been determined. Although the effective factors in shearography has been optimized, it is difficult to determine the factors exactly because they are related to the details of tracks. On the other hand, ESPI is independent on the details of a crack and only the induced load plays an important role. The out-of-plane displacement was measured under the optimized load and the measured were numerically differentiated, which resulted in an equivalent to the shearogram. The size of cracks can be determined quantitatively without any detail of a crack.