• Title/Summary/Keyword: Protection measure

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Protective Effect of Various Grain Methanolic Extracts against UVB-induced Photo-aging in Human Skin Fibroblasts (인체 피부 섬유아세포에서 자외선 조사에 대한 다양한 곡류 메탄올 추출물의 보호 효과)

  • Jeon, Jiyoung;Yang, Jinwoo;Sung, Jeehye;Seong, Yeji;Jeong, Heon Sang;Lee, Junsoo
    • The Korean Journal of Food And Nutrition
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    • v.30 no.2
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    • pp.211-217
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    • 2017
  • In the present study, we investigated the protective effect of various grain methanolic extracts against UVB-induced photo-aging in human skin fibroblasts. Various grain methanolic extracts were evaluated for their antioxidant compounds and activities. 2,2-Ddiphenyl-1-picryhydrazyl radical (DPPH) and ABTS 2,2-azino-bris-(3-ethylbenzoth iazoline-6-sulphonic acid) radical cation scavenging activities have been used to measure the relative antioxidant activities of extracts from grains. The content of total polyphenolics in the extracts were evaluated using spectrophotometric methods. Human skin fibroblast (Hs68) cells were pretreated with various grain methanolic extracts ($25{\mu}g/mL$). Skin toxicity was simulated by exposing the cells to UVB ($30mJ/cm^2$) irradiation. In response to the UVB-irradiation, an increased amount of matrix metallo-proteinases (MMPs) release was observed, whereas pretreatment of various grain methanolic extracts significantly inhibited the production of MMP-1 in Hs68 cells. We also found that pretreatment of the extracts significantly decreased UVB-induced reactive oxygen species and significantly increased total collagen content in Hs68 cells. These results provide that grains could be regarded as a potential ingredient in natural cosmetics, used for UVB protection.

Efficient Inoculation Method of Beauveria bassiana for Production of Bombycis corpus and Evaluation of Its Liver Protection Activity (백강잠(白彊蠶) 생산을 위한 Beauveria bassiana의 효율적인 접종법 및 백장잠의 간보호 활성 검정)

  • Jung, I-Yeon;Hong, In-Pyo;Kang, Pil-Don;Nam, Sung-Hee;Kim, Mi-Ja
    • Journal of Sericultural and Entomological Science
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    • v.47 no.1
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    • pp.5-11
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    • 2005
  • When inoculating with B. bassiana 101A for the mass production of B. corpus, the infection ratio was high with regardless of the treating time with highly-humidity if the concentration of spore was 1.0${\times}$$10^8$ spores/m/, but that was low if the concentration was 1.0${\times}$$10^7$ spores/m/. In the study of the activities according to the coserving temperature or days of the B. bassiana spawn, the infection ratio of 90% was maintained for 12 days in the temperature of $4^{\circ}C$. However, the infection ratio was rapidly dropped to the below of 5% after conserved for 48 hours in the temperature of $25^{\circ}C$. Besides, the activities of the original isolate had no difference after conserved for 12 months in the temperature of $4^{\circ}C$, so that the infection ratio 90% could be mintatined. In the measure of liver-protecting activities of B. bassiana 101A, the recovering effect was 43.5% and 65.7% respectively in the poisonous treatment induced with galactosamine, compared with liver-protecting activities of Silymarin and DDB in the $H_2O$ fraction. In the poisonous treatment induced with $CCl_4$ the recovering effect was 100% and 69.3% respectively, compared with liver-protecting activities of Silymarin and DDB in the EtOAc fraction.

Transboundary Environmental Harm as a Threat to National Security - Theoretical Analysis and Case Studies - (국가안보에 대한 위협으로서의 국제적 환경손상 - 환경안보의 이론과 사례에 대한 검토 -)

  • Moh, Young-Dawng
    • Korean Security Journal
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    • no.36
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    • pp.201-225
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    • 2013
  • The link between transnational environmental harm and national security has attracted new attention due to the environmental crisis such as climate change, nuclear accidents and, pollution. However, both domestic and international environmental regimes are still tied to the unsuccessful and unclear notion-sustainable development. The present author argues that environment should be considered as a security matter for the effective environmental protection. If, for example, a nation committed a serious environmental harm and the effects spans borderlines, and the source nation refuses to cooperate or compensate, would sustainable development still be an appropriate measure? Then, what would be the victim state's tool to protect its own security? The present author first looks into the possibility utilizing UN Security Council. But due to its limited legality and effectiveness in this environmental matter the present author would like to propose a non-traditional but a not-brand new method. This new method reflects two new trends both from international law and security areas. First, this approach clearly moves from the military focused security concept to broader security concept. Second, this is also a shift from traditional international law to transnational law. With these two new approaches, we will find a more suitable answer both for securing national environmental security and for protecting environment.

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Estimation of R-factor for Universal Soil Loss Equation with Monthly Precipitation Data in North Korea (북한 지역의 월 강수량으로부터 토양 유실 예측 공식 적용을 위한 강수 인자 산출)

  • Jeong, Yeong-Sang;Park, Cheol-Soo;Jeong, Pil-Kyun;Im, Jung-Nam;Shin, Jae-Sung
    • Korean Journal of Soil Science and Fertilizer
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    • v.35 no.2
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    • pp.87-92
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    • 2002
  • Soil erosion is detrimental to sustain soil productivity in north Korea, since agriculture of this country depends largely upon the slope land in mountainous area. Taking any measure for protection from erosion should be based on prediction of soil loss. Estimation of rainfall factor, R, in north Korea for the Universal Soil Loss Equation was attempted. The monthly precipitation data of the twenty six locations provided by the Korean Meteorological Adminstration were used. From the relationship between II_30 and the July-August precipitation concentration percents, the regional adjustment factor was obtained. The rainfall factor was calculated with the monthly precipitation data and the regional adjustment factor. The annual precipitation in north Korea ranged from 606 to 1,520mm, and the July-August precipitation concentration percents were 34.4 to 53.8. The regional adjustment factor ranged from 0.53 to 1.33 showing lower value in the highland and east coastal region than in the mid mountainous inland and west region. The R-factor value estimated from the monthly precipitation and the regional adjustment factor ranged from 107 to 483, which was lower than average value in south Korea.

Discussion of Exposure Evaluation Associated with Extremely Low Frequency-magnetic Field in the Case of Portable Hand-held Fans (휴대용 손 선풍기의 극저주파 자기장 발생 수준 평가와 쟁점 고찰)

  • Park, Dong-Uk;Yi, Seongjin;Kim, So-Youn;Bae, Seo-Youn;Choi, Sangjun;Kim, Won;Min, Sung Hyon;Park, Jihoon;Ahn, Jongju
    • Journal of Environmental Health Sciences
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    • v.44 no.5
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    • pp.480-490
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    • 2018
  • Objective: This study aimed to report the level of extremely low frequency-magnetic field (ELF-MF) emitted by portable hand-held fans (HHF) and to discuss the methodologies for determining the health risk of ELF-MF for HHF products. Method: ELF-MF was monitored at eight locations by distances in the vicinity of HHFs. A total of 13 HHF brands on the market were randomly selected. A portable ELF-MF monitor MDEX II was used to measure the ELF-MF level in the range of 40-800 Hz with a resolution of $0.01{\mu}T$. This study also examined the frequency results of a total of 45 HHF products investigated by the Korean Ministry of Science and ICT (KMSICT). Results: ELF-MF higher than $0.3{\mu}T$ was found to be emitted at a distance of less than 20 cm from 12 HHF. ELF-MF emitted from four products was found to exceed the reference level ($83.3{\mu}T$ based on 60 Hz) recommended by the International Commission on Non-Ionizing Radiation Protection (ICNIRP). KMSIT reported that the principle frequency emitted from the HHFs ranged from 54 Hz to 284 kHz, without the level of LEF-MF. Unscientifically, the KMSICT used the reference level by ICNIRP as the chronic level and concluded that all HHFs are safe with a basis of 1.2-36.0% less than the reference level. Conclusion: The HHF emitted much higher levels of ELF-MF than $0.3-0.4{\mu}T$, which is regarded as the reference level for childhood leukemia. The risk of HHF should be examined in terms of whether they can be used by the general public, including children and pregnant woman.

A Study on the Curriculum of Department Security Secretarial Programs in Korea University (국내 대학 경호비서학과의 교육과정 특성에 관한 연구 - 4년제 대학을 중심으로 -)

  • Gong, Bae-Wan
    • Korean Security Journal
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    • no.13
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    • pp.1-21
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    • 2007
  • This study aims to analysis and measure on the curriculum of security programs in Korean university as the private security system. Civil security demand social safety life by the police protection and private security system. The private security or the civil guards shows rapid growth by the social development and improve the quality of life. But the supply and training system have some limitations in spite of the high demand guard-secretary. The main role of secretaries has been to accompany superiors in order to maintain their dignity or trait. Then the secretaries are required to play additional roles of safety managers such as a security manager, a protocol manager, an intelligence manager and a protective driver in order to overcome the domestic and the international safety environment and to elevate the quality of service as a competitive work. So, the purpose of this article is to analyze current situation of civil body and security guard training industry and to seek an educational model. For that, we examine in 'Do the professional training organizations meet social demand for the body and security guards'? And, 'What kind of training has to be provide for the body and security guards'? and 'What the qualifications of the trainers'? Then, 'What are the differences in training courses between private organizations and universities'? 'Is there differences in the job placement among the trainers of private organizations and universities'? etc.. Conclusion, the social demand common curriculum for the body and security guard will be drawn from the analysis of diverse training organizations with different training courses in contents, training periods, educational value, and social aim. Then we have to a standard curriculum for the successful training education system to provide social security.

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A Study on the Effects of Fire-Resistant Coating Materials for Prevention of Concrete Spalling (콘크리트 폭렬 저감에 대한 내화 피복재의 영향에 관한 연구)

  • Jeong, Eui-Dam;Song, Myong-Shin;Kang, Hyun-Ju;Kang, Seung-Min
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.5
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    • pp.9-15
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    • 2010
  • Recently, the high-compressive strength concrete where the use is extending was weak in fire because of spalling that was occurring with rise of internal vapor pressure by high temperature. For preventing spalling of high-strength concrete in fire, Organic fibers have been using in concrete generally. By melting of organic fibers in concrete in fire, the internal moistures of concrete moves quickly to the outside, and so, preventing of spalling of high-strength concrete. But this method will be able to prevent the spalling of high-strength concrete, but makes the decrease of the concrete strength after fire. This study make a comparison between properties of preventing of spalling and remaining compressive strength of concrete using intumescence Alkali-Silicates fire-resistant material and that of concrete with organic fibers. Using organic fibers for preventing of spalling of concrete are P.P and Nylon fibers, and anti-fire intumescence material for protection of concrete surface is alkali-silicate materials. Fire resistance test executed as long as 3 hr under the flame temperature $1,200^{\circ}C$ over. In the case of concrete with P.P fibers, don't occurred the spalling, but the remaining compressive strength will not be able to measure, the concrete using intumescence Alkali-Silicates system fire-resistant material is not only preventing of the spalling but also the remaining compressive strength maintained until the maximum 96%.

Aspects of Staphylococcus in Povidone Disinfection of Patients with a Tracheostomy (기관절개술 환자의 Povidone 소독에 따른 포도상구균의 양상)

  • Hong, Hae-Sook;Kim, Yun-Kyung
    • Journal of Korean Biological Nursing Science
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    • v.3 no.2
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    • pp.1-20
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    • 2001
  • The object of this study was to measure the biocidal effect of povidone on staphylococcus found in tracheal incision site, change following the disinfection frequency and duration, and tolerance to the antibiotics. The data was analysed by percentage and t-test using SAS program. The subjects of this study are 35 tracheostomy patients in and Intensive Care Unite of the hospital located in Daegu city and analysing term was from January 16 to February 26, 2001. The results of this study were as follows. The biocidal effect of povidone on Staphylococcus was strong regardless of time and concentration. Staphylococcus aureus was found on third day and found to be highest concentration on 6th day after disinfection of once/a day. Coagulase negative Staphylococcus was not found from 1st to 3rd day and highest on 4th day after disinfection of once/a day. As to bacteria colonization following the disinfection frequency, twice per day of disinfection was more effective on Staphylococcus aureus than once a day. In tolerance test of Staphylococcus aureus and Coagulase negative Staphylococcus, 72.7% of Staphylococcus aureus showed tolerance in Methicillin, 63.6% in Imipenem, and 37.5% of Coagulase negative Staphylococcus showed tolerance in Methicillin, 12.5% in Imipenem. Both of them do not have any tolerance in Vancomycin. The results of this study can be used as the basis for protection against hospital mediated infection through thorough disinfection. With above results, I suggest the following. First, we should research relation between antiseptics and fungi, virus more deeply. Secondly, all medical personnel should try to protect against the hospital medicated infection. Thirdly, there is a need of training professional disinfection personnel for preventing hospital mediated infection and the progress of nursing science.

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Absorbed and effective dose for periapical radiography using portable and wall type dental X-ray machines (이동형 구내방사선촬영기와 벽걸이 구내방사선촬영기로 촬영한 치근단 방사선촬영에서 환자의 흡수선량과 유효선량 평가)

  • Han, Won-Jeong
    • The Journal of Korean Academy of Prosthodontics
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    • v.50 no.3
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    • pp.184-190
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    • 2012
  • Purpose: The purpose of this study was to measure the absorbed dose and to calculate the effective dose for one periapical radiography using the portable and wall type dental X-ray machines. Materials and methods: Thermoluminescent chips were placed at 25 sites throughout the layers of the head and neck of a tissue-equivalent human skull phantom. The man phantom was exposed with the portable and wall type dental X-ray machines. For one periapical radiography taken by portable dental X-ray machine, the exposure setting was 60 kVp, 2 mA and 0.2 seconds, while for one periapical radiography taken by wall type dental X-ray machine, exposure setting was 70 kVp, 8 mA and 0.074 seconds. Absorbed dose measurements were performed and equivalent doses to individual organs were summed using ICRP 103 to calculate effective dose. Results: In the upper anterior periapical radiography using portable dental X-ray machine and in the lower posterior periapical radiography using both machines, the highest absorbed dose was recorded at the mandible body. The effective dose in upper anterior periapical radiography using portable and wall type dental X-ray machines was $4{\mu}Sv$, $2{\mu}Sv$, respectively. In the lower posterior periapical radiography, the effective dose for each portable and wall type dental X-ray machines was $6{\mu}Sv$, $2{\mu}Sv$. Conclusion: It was recommended that the operator use prudently potable dental X-ray machine because that the effective dose in the periapical radiography using wall type dental X-ray machine was lower than that in the periapical radiography using portable dental X-ray machine.

Anti-Inflammatory Effect of Ixeris dentata on Ultraviolet B-Induced HaCaT Keratinocytes

  • Kim, Sung-Bae;Kang, Ok-Hwa;Keum, Joon-Ho;Mun, Su-Hyun;An, Hyun-Jin;Jung, Hyun-Ju;Hong, Seung-Heon;Jeong, Dong-Myong;Kweon, Kee-Tae;Kwon, Dong-Yeul
    • Natural Product Sciences
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    • v.18 no.1
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    • pp.60-66
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    • 2012
  • Human skin is the first line of defense for the protection of the internal organs of the body from different stimuli. Ultraviolet B (UVB) irradiation induces skin damage and inflammation through the secretion of various cytokines, which are immune regulators produced by cells. To prevent the initiation of skin inflammation, keratinocytes that have been irreversibly damaged by radiation must be removed through the apoptotic mechanism. Ixeris dentata (family: Asteraceae) is a perennial medicinal herb indigenous to Korea. It has been used in Korea, China, and Japan to treat in digestion, pneumonia, diabetes, hepatitis, and tumors. To gain insight into the anti-inflammatory effects of I. dentata, we examined its influence on UVB-induced pro-inflammatory cytokine production in human keratinocytes (HaCaT cells), by observing cells that were stimulated with UVB in the presence or absence of I. dentata. In the present study, pro-inflammatory cytokine production was determined by performing enzyme-linked immunosorbent assay, reverse transcription polymerase chain reaction, and western blot analysis to measure the activation of mitogen-activated protein kinase (MAPKs). I. dentata inhibited UVBinduced production of the pro-inflammatory cytokine interleukin (IL)-6 in a dose-dependent manner. Further, I. dentata inhibited the UVB-induced expression of cyclooxygenase (COX)-2. Furthermore, I. dentata inhibited the phosphorylation of c-Jun NH2-terminal kinase and p38 MAPKs, suggesting that it inhibits the secretion of the pro-inflammatory cytokines IL-6 and IL-8, and COX-2 expression, by blocking MAPK phosphorylation. These results suggest that I. dentate can potentially protect against UVB-induced skin inflammation.