• Nutrition Research and Practice
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• v.15 no.2
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• pp.137-159
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• 2021

Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to as n-3 LCPUFA. They have been extensively studied for their effects in human nutrition and health. This paper provides an overview on metabolism, sources, dietary intake, and status of n-3 LCPUFA. A summary of the dietary recommendations for n-3 LCPUFAs for different age groups as well as specific physiological conditions is provided. Evidence for n-3 LCPUFA in cardiovascular diseases, including new studies, is reviewed. Expert recommendations generally support a beneficial effect of n-3 LCPUFA on cardiovascular health and recommend a daily intake of 500 mg as DHA and EPA, or 1-2 servings of fish per week. The role of n-3 LCPUFA on brain health, in particular neurodegenerative disorders and depression, is reviewed. The evidence for beneficial effects of n-3 LCPUFA on neurodegenerative disorders is non-conclusive despite mechanistic support and observational data. Hence, no definite n-3 LCPUFA expert recommendations are made. Data for the beneficial effect of n-3 LCPUFA on depression are generally compelling. Expert recommendations have been established: 200-300 mg/day for depression; up to 1-2 g/day for major depressive disorder. Recent studies support a beneficial role of n-3 LCPUFAs in reducing the risk for premature birth, with a daily intake of 600-800 mg of DHA during pregnancy. Finally, international experts recently reviewed the scientific evidence on DHA and arachidonic acid (ARA) in infant nutrition and concluded that the totality of data support that infant and follow-on formulas should provide both DHA and ARA at levels similar to those in breast milk. In conclusion, the available scientific data support that dietary recommendations for n-3 LCPUFA should be established for the general population and for subjects with specific physiological conditions.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.4
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• pp.12-22
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• 2021

This article suggests the machine learning model, i.e., classifier, for predicting the production quality of free-machining 303-series stainless steel(STS303) small rolling wire rods according to the operating condition of the manufacturing process. For the development of the classifier, manufacturing data for 37 operating variables were collected from the manufacturing execution system(MES) of Company S, and the 12 types of derived variables were generated based on literature review and interviews with field experts. This research was performed with data preprocessing, exploratory data analysis, feature selection, machine learning modeling, and the evaluation of alternative models. In the preprocessing stage, missing values and outliers are removed, and oversampling using SMOTE(Synthetic oversampling technique) to resolve data imbalance. Features are selected by variable importance of LASSO(Least absolute shrinkage and selection operator) regression, extreme gradient boosting(XGBoost), and random forest models. Finally, logistic regression, support vector machine(SVM), random forest, and XGBoost are developed as a classifier to predict the adequate or defective products with new operating conditions. The optimal hyper-parameters for each model are investigated by the grid search and random search methods based on k-fold cross-validation. As a result of the experiment, XGBoost showed relatively high predictive performance compared to other models with an accuracy of 0.9929, specificity of 0.9372, F₁-score of 0.9963, and logarithmic loss of 0.0209. The classifier developed in this study is expected to improve productivity by enabling effective management of the manufacturing process for the STS303 small rolling wire rods.

• Journal of Dairy Science and Biotechnology
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• v.40 no.3
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• pp.110-121
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• 2022

The root of ginger (Zingiber officinale) contains gingerol, which is known to be responsible for its pharmacological activity. The essential oil extracted from ginger has been found to have various pharmacological effects. Thus, interest in the development of various beverages using ginger oil has recently increased. Therefore, in this study, the organoleptic quality assessment of cow milk, yogurt, kefir, soy milk, oat milk, and almond milk was conducted by supplementing them with oil extracted from ginger at various concentrations (supplemented with 0.5% increments from 0% up to 2%). A poor grade was obtained in the organoleptic quality evaluation, owing to the strong odor of ginger oil. However, when compared to that of the control, the samples supplemented with 0.5% ginger oil showed a good grade of organoleptic quality assessment. Therefore, this study is considered valuable as it is the first study to review the organoleptic quality assessment by supplementing milk, yogurt, kefir, soy milk, oat milk, and almond milk with ginger oil. Additionally, in order to improve organoleptic quality assessment, it is critical to estimate how much ginger oil supplementation concentration could be reduced and whether ginger oil exhibits various bio-activities at this concentration.

• Journal of the Korea Convergence Society
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• v.12 no.7
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• pp.159-167
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• 2021

The increasingly severe environmental problems such as resource depletion and ecological damage, and consumers' concern for sustainable fashion, make the fashion industry chain develop towards green energy saving. The purpose of this study is to explore the attitude and consumption psychology of specific groups towards sustainable fashion consumption, as well as their specific views and attitudes towards recycled textiles or fabrics for re-manufacturing clothing. This paper attempts to understand how the characteristics of recycled clothing affect consumer. Based on the review of relevant literature, a series of determinants affecting consumer behavior is determined, and the characteristics of recycled products, such as expression value and social value, are determined. An online questionnaire was designed based on this conceptual framework, and 226 valid, complete answers were received. The results show that the emphasis on social value and environmental protection consciousness can effectively affect consumers' decision-making. These findings were helpful to the research of whole green environmental protection and ecological clothing recycling industry system, promote the sustainable development of the clothing industry.

• Journal of The Korean Society of Agricultural Engineers
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• v.64 no.6
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• pp.25-34
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• 2022

Recently, as a study to air cooled slag, which is an industrial by-product, research is being proceed to use it as a material for concrete. In this study, the workability, air content, compressive strength, CO₂ emission and economic feasibility of concrete were analyzed when air cooled slag, an industrial by-product, was applied as aggregate for rural road pavement concrete. As a result of the analysis, both the slump and air contents test results of concrete using the air cooled slag aggregate satisfied the target values, and the compressive strength was increased when the air cooled slag aggregate was used compared to when the natural aggregate was applied. On the other hand, the largest amount of CO₂ emission by raw material was found in aggregate. The carbon emission of rural road pavement concrete using air cooled slag aggregate increased when the Korean LCI DB was applied compared to when natural and crushed aggregates were applied, and the emission decreased when the German LCI DB was applied. This results are due to differences in the viewpoints of industrial by-products. However, considering the recycling of waste from the environmental aspect, it is necessary to simultaneously review the CO₂ emission and recycling aspects in the future. Also, the application of air cooled slag aggregate had the effect of improving the economic efficiency of rural road pavement concrete about 18.75%.

• Journal of Ginseng Research
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• v.46 no.1
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• pp.39-53
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• 2022

Ginsenoside Rb₁ (Rb₁), one of the most important ingredients in Panax ginseng Meyer, has been confirmed to have favorable activities, including reducing antioxidative stress, inhibiting inflammation, regulating cell autophagy and apoptosis, affecting sugar and lipid metabolism, and regulating various cytokines. This study reviewed the recent progress on the pharmacological effects and mechanisms of Rb₁ against cardiovascular and nervous system diseases, diabetes, and their complications, especially those related to neurodegenerative diseases, myocardial ischemia, hypoxia injury, and traumatic brain injury. This review retrieved articles from PubMed and Web of Science that were published from 2015 to 2020. The molecular targets or pathways of the effects of Rb₁ on these diseases are referring to HMGB1, GLUT4, 11β-HSD1, ERK, Akt, Notch, NF-κB, MAPK, PPAR-γ, TGF-β1/Smad pathway, PI3K/mTOR pathway, Nrf2/HO-1 pathway, Nrf2/ARE pathway, and MAPK/NF-κB pathway. The potential effects of Rb₁ and its possible mechanisms against diseases were further predicted via Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and disease ontology semantic and enrichment (DOSE) analyses with the reported targets. This study provides insights into the therapeutic effects of Rb₁ and its mechanisms against diseases, which is expected to help in promoting the drug development of Rb₁ and its clinical applications.

• KNOM Review
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• v.23 no.2
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• pp.11-17
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• 2020

Currently, the web page that provides residual substance information provides information on residual acceptance criteria in food for pesticides and veterinary drugs. Residual substances refer to pesticides or veterinary drugs that are left in agricultural, livestock, or marine products after being used by diluting them thousands of times. However, users are experiencing inconvenience due to the lack of information on pesticides and veterinary drugs, delays in search time, and Web page errors. In addition, the manager has the inconvenience of manually entering information such as residual acceptance criteria and analysis methods. Thus, this paper proposes a system that can efficiently manage and update the history of changes in information, such as residual material standards for pesticides, animal medicines and the characteristics of drugs.

• International Journal of Computer Science & Network Security
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• v.22 no.10
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• pp.97-106
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• 2022

Objective. Nanotechnology is spreading among all areas of life, from everyday devices to medicine. The concept of nanotechnology argues that not only can new physical and chemical properties of materials be discovered, but also the new potential of nanostructures when reduced to the nanoscale. The growing interest in the application of nanomaterials in dentistry contributes to the proliferation of the range of nanomaterials used by specialists. The purpose of this review of information sources was to analyze the prospects for the use of nanomaterials in dentistry. Methods. We used the bibliographic semantic method of research, for which we analyzed electronic databases of primary literature sources Scopus, Web of Science, Research Gate, PubMed, MDPI, and MedLine. English-language scientific articles published after 2017 were taken into consideration. Results. According to the results of a search study among modern information primary sources, nanotechnology improves the preventive properties of oral care products, improves the structural-mechanical and aesthetic properties of composite mixtures for dentistry, overcomes the problems of the clinical application of dental implants. Despite the prospects of nanotechnology applications in medicine in general and dentistry in particular, the existing economic and technological problems require a thorough solution for further implementation of nanostructures. Scientific novelty. For the first time, the analysis of modern trends in the application of nanotechnology in dentistry is carried out and the peculiarities of materials are highlighted, the problems and prospects of nanostructures implementation in modern dental implantology are given, physical, chemical, mechanical, and antibacterial properties of nanomaterials are evaluated. The effect of nanomaterials on the microbial adhesion of the tooth or implant surface is described. Practical significance. The presented publication can become a scientific basis for the solution of urgent problems hindering the introduction of nanotechnology into dental practice. Conclusions. Thus, the use of nanostructures opens up great opportunities for the treatment of a wide range of diseases, not only of dental nature but also in medicine in general.

• Applied Chemistry for Engineering
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• v.33 no.4
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• pp.335-342
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• 2022

In the agricultural sector where the fossil fuels are primary energy resources, the current global energy crisis together with the dissemination of smart farming has led to the new phase of energy pattern in which the electricity demand is growing faster particularly. Therefore, the fuel cell combined heat and power system, coupling the environmentally friendly fuel cell to biomass treatment and feeding, can be regarded as the most effective energy system in agriculture. In this mini-review, we discuss the R&D trend of the fuel cell combined heat and power system aimed at utilizing agricultural by-products as fuels and highlight the issues in terms of the process configuration and interconnection of individual processes.

• Korean journal of applied entomology
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• v.61 no.1
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• pp.211-219
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• 2022

Over the past decade, double-stranded RNA (dsRNA)-mediated gene silencing technology has progressed significantly for pest management in agriculture and for protecting beneficial insects from pathogens. Recently, breakthroughs in RNA interference (RNAi) applications for insect pest management by academia and commercial entities have provided RNAi products as commercial biopesticides. Although RNAi technology has vast potential and advantages for pest control, challenges, and limitations remain in practical applications. This review explores current challenges in the development of dsRNAs as a pest management tool and considers new approaches to overcome biological and environmental obstacles, such as poor stability and resistance.