• Nutrition Research and Practice
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• 제15권2호
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• pp.137-159
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• 2021

Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to as n-3 LCPUFA. They have been extensively studied for their effects in human nutrition and health. This paper provides an overview on metabolism, sources, dietary intake, and status of n-3 LCPUFA. A summary of the dietary recommendations for n-3 LCPUFAs for different age groups as well as specific physiological conditions is provided. Evidence for n-3 LCPUFA in cardiovascular diseases, including new studies, is reviewed. Expert recommendations generally support a beneficial effect of n-3 LCPUFA on cardiovascular health and recommend a daily intake of 500 mg as DHA and EPA, or 1-2 servings of fish per week. The role of n-3 LCPUFA on brain health, in particular neurodegenerative disorders and depression, is reviewed. The evidence for beneficial effects of n-3 LCPUFA on neurodegenerative disorders is non-conclusive despite mechanistic support and observational data. Hence, no definite n-3 LCPUFA expert recommendations are made. Data for the beneficial effect of n-3 LCPUFA on depression are generally compelling. Expert recommendations have been established: 200-300 mg/day for depression; up to 1-2 g/day for major depressive disorder. Recent studies support a beneficial role of n-3 LCPUFAs in reducing the risk for premature birth, with a daily intake of 600-800 mg of DHA during pregnancy. Finally, international experts recently reviewed the scientific evidence on DHA and arachidonic acid (ARA) in infant nutrition and concluded that the totality of data support that infant and follow-on formulas should provide both DHA and ARA at levels similar to those in breast milk. In conclusion, the available scientific data support that dietary recommendations for n-3 LCPUFA should be established for the general population and for subjects with specific physiological conditions.

• 산업경영시스템학회지
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• 제44권4호
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• pp.12-22
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• 2021

This article suggests the machine learning model, i.e., classifier, for predicting the production quality of free-machining 303-series stainless steel(STS303) small rolling wire rods according to the operating condition of the manufacturing process. For the development of the classifier, manufacturing data for 37 operating variables were collected from the manufacturing execution system(MES) of Company S, and the 12 types of derived variables were generated based on literature review and interviews with field experts. This research was performed with data preprocessing, exploratory data analysis, feature selection, machine learning modeling, and the evaluation of alternative models. In the preprocessing stage, missing values and outliers are removed, and oversampling using SMOTE(Synthetic oversampling technique) to resolve data imbalance. Features are selected by variable importance of LASSO(Least absolute shrinkage and selection operator) regression, extreme gradient boosting(XGBoost), and random forest models. Finally, logistic regression, support vector machine(SVM), random forest, and XGBoost are developed as a classifier to predict the adequate or defective products with new operating conditions. The optimal hyper-parameters for each model are investigated by the grid search and random search methods based on k-fold cross-validation. As a result of the experiment, XGBoost showed relatively high predictive performance compared to other models with an accuracy of 0.9929, specificity of 0.9372, F₁-score of 0.9963, and logarithmic loss of 0.0209. The classifier developed in this study is expected to improve productivity by enabling effective management of the manufacturing process for the STS303 small rolling wire rods.

• Journal of Dairy Science and Biotechnology
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• 제40권3호
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• pp.110-121
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• 2022

The root of ginger (Zingiber officinale) contains gingerol, which is known to be responsible for its pharmacological activity. The essential oil extracted from ginger has been found to have various pharmacological effects. Thus, interest in the development of various beverages using ginger oil has recently increased. Therefore, in this study, the organoleptic quality assessment of cow milk, yogurt, kefir, soy milk, oat milk, and almond milk was conducted by supplementing them with oil extracted from ginger at various concentrations (supplemented with 0.5% increments from 0% up to 2%). A poor grade was obtained in the organoleptic quality evaluation, owing to the strong odor of ginger oil. However, when compared to that of the control, the samples supplemented with 0.5% ginger oil showed a good grade of organoleptic quality assessment. Therefore, this study is considered valuable as it is the first study to review the organoleptic quality assessment by supplementing milk, yogurt, kefir, soy milk, oat milk, and almond milk with ginger oil. Additionally, in order to improve organoleptic quality assessment, it is critical to estimate how much ginger oil supplementation concentration could be reduced and whether ginger oil exhibits various bio-activities at this concentration.

• 한국융합학회논문지
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• 제12권7호
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• pp.159-167
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• 2021

자원 고갈, 생태 파괴 등 날로 심각해지는 환경문제와 지속가능한 패션에 대한 소비자들의 관심은 패션 산업 사슬을 녹색 에너지 절약 방향으로 발전하게 하였다. 본 연구는 특정 집단의 지속가능한 패션 소비에 대한 태도와 심리를 탐구하고 재생 방직품 또는 재제조 의류 원단에 대한 그들의 구체적 인식과 태도를 탐구하는데 취지를 두었다. 본문은 구제 의류의 특성이 소비자에 미치는 영향에 대해 알아보았다. 관련 문헌자료를 찾아본 기초에서 소비자에 영향을 주는 일련의 결정적 요소와 재생품의 표현 가치, 사회적 가치 등 특징을 확정했다. 이 이론적 배경에 근거해 온라인 설문조사를 설계했으며 총 226개의 유효 응답을 받았다. 조사 결과에 따르면 사회적 가치와 환경보호에 대한 중시가 소비자의 결정에 영향을 미치는 것으로 나타났다. 이상 연구 결과는 전체 녹색 환경보호와 생태 의류 회수 산업 체계의 연구에 도움이 되며 의류 산업의 지속가능한 발전을 추진한다.

• 한국농공학회논문집
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• 제64권6호
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• pp.25-34
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• 2022

Recently, as a study to air cooled slag, which is an industrial by-product, research is being proceed to use it as a material for concrete. In this study, the workability, air content, compressive strength, CO₂ emission and economic feasibility of concrete were analyzed when air cooled slag, an industrial by-product, was applied as aggregate for rural road pavement concrete. As a result of the analysis, both the slump and air contents test results of concrete using the air cooled slag aggregate satisfied the target values, and the compressive strength was increased when the air cooled slag aggregate was used compared to when the natural aggregate was applied. On the other hand, the largest amount of CO₂ emission by raw material was found in aggregate. The carbon emission of rural road pavement concrete using air cooled slag aggregate increased when the Korean LCI DB was applied compared to when natural and crushed aggregates were applied, and the emission decreased when the German LCI DB was applied. This results are due to differences in the viewpoints of industrial by-products. However, considering the recycling of waste from the environmental aspect, it is necessary to simultaneously review the CO₂ emission and recycling aspects in the future. Also, the application of air cooled slag aggregate had the effect of improving the economic efficiency of rural road pavement concrete about 18.75%.

• Journal of Ginseng Research
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• 제46권1호
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• pp.39-53
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• 2022

Ginsenoside Rb₁ (Rb₁), one of the most important ingredients in Panax ginseng Meyer, has been confirmed to have favorable activities, including reducing antioxidative stress, inhibiting inflammation, regulating cell autophagy and apoptosis, affecting sugar and lipid metabolism, and regulating various cytokines. This study reviewed the recent progress on the pharmacological effects and mechanisms of Rb₁ against cardiovascular and nervous system diseases, diabetes, and their complications, especially those related to neurodegenerative diseases, myocardial ischemia, hypoxia injury, and traumatic brain injury. This review retrieved articles from PubMed and Web of Science that were published from 2015 to 2020. The molecular targets or pathways of the effects of Rb₁ on these diseases are referring to HMGB1, GLUT4, 11β-HSD1, ERK, Akt, Notch, NF-κB, MAPK, PPAR-γ, TGF-β1/Smad pathway, PI3K/mTOR pathway, Nrf2/HO-1 pathway, Nrf2/ARE pathway, and MAPK/NF-κB pathway. The potential effects of Rb₁ and its possible mechanisms against diseases were further predicted via Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and disease ontology semantic and enrichment (DOSE) analyses with the reported targets. This study provides insights into the therapeutic effects of Rb₁ and its mechanisms against diseases, which is expected to help in promoting the drug development of Rb₁ and its clinical applications.

• KNOM Review
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• 제23권2호
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• pp.11-17
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• 2020

현재 잔류물질정보를 제공하는 웹 페이지에서는 농약 및 동물용의약품의 식품 내 잔류허용기준 정보를 제공하고 있다. 잔류물질이란 농약 혹은 동물용의약품을 수천 배 희석하여 사용 후 농산물 또는 축, 수산물에 남아 있게 되는 극미량의 농약 혹은 동물용의약품을 뜻한다. 하지만 농약과 동물용의약품에 대한 정보의 누락, 웹 페이지 오류 등 정보 제공이 원활하게 이루어지지 않고 있기 때문에 사용자들이 불편을 겪고 있다. 또한 관리자는 잔류허용 기준 및 분석법 등 정보들을 수동으로 입력해야하는 불편함이 있다. 이에 본 논문에서는 농약 및 동물용의약품에 대한 잔류물질기준과 약품의 특성 등 정보들의 변화이력을 효율적으로 관리하고 업데이트 할 수 있는 시스템을 제안한다.

• International Journal of Computer Science & Network Security
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• 제22권10호
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• pp.97-106
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• 2022

Objective. Nanotechnology is spreading among all areas of life, from everyday devices to medicine. The concept of nanotechnology argues that not only can new physical and chemical properties of materials be discovered, but also the new potential of nanostructures when reduced to the nanoscale. The growing interest in the application of nanomaterials in dentistry contributes to the proliferation of the range of nanomaterials used by specialists. The purpose of this review of information sources was to analyze the prospects for the use of nanomaterials in dentistry. Methods. We used the bibliographic semantic method of research, for which we analyzed electronic databases of primary literature sources Scopus, Web of Science, Research Gate, PubMed, MDPI, and MedLine. English-language scientific articles published after 2017 were taken into consideration. Results. According to the results of a search study among modern information primary sources, nanotechnology improves the preventive properties of oral care products, improves the structural-mechanical and aesthetic properties of composite mixtures for dentistry, overcomes the problems of the clinical application of dental implants. Despite the prospects of nanotechnology applications in medicine in general and dentistry in particular, the existing economic and technological problems require a thorough solution for further implementation of nanostructures. Scientific novelty. For the first time, the analysis of modern trends in the application of nanotechnology in dentistry is carried out and the peculiarities of materials are highlighted, the problems and prospects of nanostructures implementation in modern dental implantology are given, physical, chemical, mechanical, and antibacterial properties of nanomaterials are evaluated. The effect of nanomaterials on the microbial adhesion of the tooth or implant surface is described. Practical significance. The presented publication can become a scientific basis for the solution of urgent problems hindering the introduction of nanotechnology into dental practice. Conclusions. Thus, the use of nanostructures opens up great opportunities for the treatment of a wide range of diseases, not only of dental nature but also in medicine in general.

• 공업화학
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• 제33권4호
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• pp.335-342
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• 2022

화석연료 사용 비중이 큰 농업분야에서는 최근 불안한 국제정제와 맞물린 에너지 가격 상승과 활발한 스마트팜 보급으로 전력사용량까지 증가하는 에너지 사용 패턴 변화로 새로운 국면을 맞고 있다. 따라서 친환경 분산형 전원으로 연료전지를 이용하며, 바이오매스를 직접 연료로 사용할 수 있는 연료전지 열병합발전 시스템은 농가에 열 및 전기에너지를 동시에 공급할 수 있는 효과적인 에너지시스템으로 인식되고 있다. 본 총설 논문에서는 바이오매스, 특히 농업부산물을 연료로 활용하기 위한 연료전지 기반의 열병합발전 시스템에 대한 공정 구성과 기술적 동향을 제시하고, 통합 연계공정 설계 시 고려해야 할 부분들을 논의하고자 한다.

• 한국응용곤충학회지
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• 제61권1호
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• pp.211-219
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• 2022

지난 10년 동안, 이중 가닥 RNA (double-stranded RNA, dsRNA)를 이용한 특정 유전자 발현 간섭(RNA interference, RNAi) 기술은 의약품 개발뿐만 아니라 작물보호 분야에 해충방제부터 익충보호까지 다양하게 그 기술이 사용되어 왔다. 그동안 학계 및 산업체에서 활발히 연구되어 온 RNAi기술을 이용한 작물 및 익충보호제는 상용화를 눈앞에 두고 있다. 미래 농업 시장에서 해충방제제와 익충보호제로써의 개발을 위한 RNAi의 기술적 응용은 상당한 잠재력을 가지고 있지만, 현장에 직접 사용되기에는 아직 여러 가지 한계점이나 극복해야 할 과제가 남아있다. 본 리뷰에서는 최근에 활발히 진행되고 있는 작물보호제 및 익충보호제(protection of crops and beneficial insects)로써의 dsRNA의 다양한 활용과 그 잠재성(potential)을 소개하고자 한다.