• BMB Reports
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• 제50권7호
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• pp.384-389
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• 2017

The Nogo-B receptor (NgBR) is necessary for not only Nogo-B-mediated angiogenesis but also vascular endothelial growth factor (VEGF) -induced angiogenesis. However, the molecular mechanisms underlying the regulatory role of the VEGF-NgBR axis in angiogenesis are not fully understood. Here, we report that miR-26a serves as a critical regulator of VEGF-mediated angiogenesis through directly targeting NgBR in endothelial cells (ECs). Stimulation of ECs by VEGF increased the expression of NgBR and decreased the expression of miR-26a. In addition, miR-26a decreased the VEGF-induced migration and proliferation of ECs. Moreover, miR-26a overexpression in ECs decreased the VEGF-induced phosphorylation of the endothelial nitric oxide synthase (eNOS) and the production of nitric oxide, which is important for angiogenesis. Overall, these data suggest that miR-26a plays a key role in VEGF-mediated angiogenesis through the modulation of eNOS activity, which is mediated by its ability to regulate NgBR expression by directly targeting the NgBR 3'-UTR.

• 한국지역사회생활과학회지
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• 제16권2호
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• pp.61-73
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• 2005

This study aims to examine the socio-demographic heterogeneity of community participation in rural Korea. Data was collected through interviews with 1,870 rural householders and housewives who have lived in Up or Myen as an administrative unit of rural communities, and analyzed by the SPSS/PC Win V.10 program. The statistical techniques used for this study were frequency and percentile. The major findings of this study were as follows. Firstly, the extent to which rural people have participated in community organizations were: cooperative groups, $80.8\%$; religious groups, $20.6\%$; learning groups, $12.7\%$; political groups, $9.8\%;$ civil groups $6.7\%$; and voluntary groups, $5.3\%$. Whereas the numbers were high for community participation in groups related to agricultural production, participation in civil and voluntary groups were lower. Secondly, it showed that people who lived in urbanized and high population density areas were more likely to participate in community groups. The diversity of community organizations was different according to the level of rurality. Thirdly, farm householders were more likely to participate in religious, civil and voluntary groups than non-farm householders. Fourthly, people with higher education, females, those in the 40 to 50 age groups were more likely to participate in community organizations. Fifthly, even though men are more likely to participate in political parties, women were more likely then men to agree that women should participate in political parties. This empirical study could support the results of Sundeen (1988) and Wilson and Musick (1997) in that education was related positively to community participation. In addition, we concluded that community participation in a rural development process has two main considerations: philosophical and pragmatic. This implies that there is room for government to enable and facilitate 'true' community participation. That can be done through policy reform which creates a permissive environment for community decision-making and input, in addition to simply supporting community development through financial assistance.

• 한국지역사회생활과학회지
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• 제28권4호
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• pp.581-597
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• 2017

This study evaluated the effect of consumers' knowledge and attitude toward to local foods on purchase intention. The study data were collected through a three-week online survey of 500 household food purchasers who had bought local foods within the previous year. The results are as follows. First, examining the difference in the knowledge of local foods according to socio-demographic variables revealed that married people had more knowledge of local foods than singles according to marital status, and college graduates and higher had more knowledge than high school graduates and lower according to education level. Second, as a result of examining the difference in attitudes towards local foods according to socio-demographic variables, married people more than single people according to marital status, people in their 30s more than those in their 20s according to age and college graduates and higher more than high school graduates and lower according to education level had more positive attitudes towards local foods. Third, as a result of examining the difference in consumers' purchase intention towards local foods according to socio-demographic variables, according to age, and housewives had the lowest purchase intention towards local foods according to occupation. (Ed- I cannot understand: the section 'according to socio-demographic variables, according to age, and housewives had' is confused) People engaged in office/specialized/managerial jobs and those engaged in production/sales/service had the highest purchase intention. In regard to monthly average income, households that made less than KRW 4 million had the lowest purchase intention, and those that made KRW 4-8 million had the highest purchase intention. Fourth, the knowledge of local foods affected attitudes towards local foods. Fifth, attitudes towards local foods affected consumers' purchase intention. In other words, people with positive attitudes towards local foods had higher purchase intention.

• 산업진흥연구
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• 제1권2호
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• pp.49-54
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• 2016

본 연구는 중소제조업의 체계적 문서화가 생산성에 미치는 영향을 분석하였다. 연구결과 문서화 업무체계 확립은 불량감소(p<.01)와 설비가동률 향상(p<.05)에 영향을 미쳤으며 문서화 교육훈련 정도는 불량감소(p<.05)와 생산성 향상(p<.01)에 유의한 영향을 미쳤다. 문서화 경험은 생산성 향상에 유의한 영향을 미치지는 못했다. 즉, 문서화 업무체계가 높을수록 불량감소, 설비가동률 향상 정도가 높으며 문서화에 대한 교육훈련이 잘 되어 있을수록 불량감소, 생산성 향상의 긍정적 효과를 보이고 있어 중소제조업은 문서화의 경험적 측면에 의존하기 보다는 문서화 업무체계를 확립하고 교육훈련을 실시하여 생산성을 높이기 위한 노력이 필요한 것으로 나타났다. 본 연구는 중소제조업의 체계적 문서화가 생산성에 미치는 영향을 분석함으로써 불량감소, 생산성향상, 설비가동율 향상에 대한 문서화 요인의 중요도를 파악하고 품질관리 측면에서 문서화의 효과를 검증한 데 연구의 의의가 있다.

• 보건교육건강증진학회지
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• 제20권4호
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• pp.51-65
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• 2003

Objectives： To examine the regional mortality differences in The Republic of Korea according to geographic location. Methods： All 232 administrative districts of the Republic of Korea in 1998 were studied according to their geographic locations by dividing each district into three categories； "metropolis," "urban," and "rural". Crude mortality rates for doth sexes from total deaths as well as the three major causes of death in Korea (cardiovascular disease, cancer, and external causes) were calculated with raw data from the "1998 report on the causes of death statistics" and resident registration data. Standardized mortality ratios (SMR) were calculated using the indirect standardization method. Poisson regression analyses were performed to examine the effects of geographic locations on the risk of death. To correct for the socioeconomic differences of each region, the percentage of old ($\geq$ 65 years old) population, the number of privately owned cars per 100 population, and per capita manufacturing production industries were included in the model. Results： Most SMRs were the lowest in the metropolis and the highest in the rural areas. These differences were more prominent in men and in deaths from external causes. In deaths from cancer in women, the rural region showed the lowest SMR. In Poisson regression analysis after correcting for regional socioeconomic differences, the risk of death from all causes significantly increased in both urban (OR＝1.111) and rural (OR＝1.100) regions, except for rural women, compared to the metropolis region. In men, the rural region showed higher risk (OR＝1.180) than the urban region (OR＝1.l51). For cardiovascular disease and cancer, significant differences were not found between geographic locations, except in urban women for cardiovascular disease (OR＝1.151) and in rural women for cancer (OR＝0.887), compared to metropolis women. In deaths from external causes, the risk ratios significantly increased in both urban and rural regions and an increasing tendency from the metropolis to the rural region was clearly observed in both sexes. Conclusions： Regional mortality differences according to geographic location exist in The Republic of Korea and further research and policy approaches to reduce these differences are needed. to reduce these differences are needed.

• 한국지역지리학회지
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• 제22권4호
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• pp.843-855
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• 2016

본 연구는 지형학적 관점에서 대형옹관의 생산유적인 가마유적과 소비유적인 옹관묘 및 옹관고분의 입지특성을 밝히고 이를 토대로 대형옹관의 유통 경로를 추정하여 수운의 가능성을 제시하고자 하였다. 이를 위해 영산강 및 지류하천의 감조하천의 상한 지점과 하해혼성평탄지의 분포를 통해 도출된 조수의 영향권을 분석하였다. 분석결과 총 21개의 소비유적이 하천의 영산강 본류의 감조상한선인 지석천 합류점 이하의 구간에 입지하고 있으며, 이 중 18개소의 유적은 하해혼성평탄지와 접근성이 매우 높은 것으로 나타났다. 이를 바탕으로 영산강 유역의 소비유적들이 생산 유적으로부터 수운을 통한 옹관의 유통이 가능한 범위 내에 입지하였으며, 고대인들이 유적 입지 선정 시 수운이 가능 환경을 일부분 고려하였다는 사실을 추정할 수 있다.

• 한국가구학회지
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• 제20권5호
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• pp.467-479
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• 2009

The high-tech computer technology developments have greatly affected the area of design education. Starting from the mid 80s, innovations in visual presentation methods have heightened with 2D computer graphic programs, CAD & 3D modeling, and Rapid Prototype that allows dimensional generation. The specialty and quality in design studio education have advanced due to the development in presentation methods such as Power Point and Keynote. But there are many problems with the current method of presenting the visual outcome in a data format using beam projectors, which is a vertical presenting method compared to the old studio study method of conducting discussions and reviews based on the substantial outcome. The essence of studio study that allows for comparisons and analysis by horizontally opening up the various work outcomes is being offset. Also the requirement for manual idea sketching work that plays an important role in the initial design phase continuing to decrease due to the digital working process dependence and cumbersome procedures in the presentation. In order to resolve this problem, the CALM system (Class Applied LCD Modular System) has been developed that replaces the method of attaching the sketches or renderings on the wall with a digital multi-display system. In a nutshell, individuals will upload the outcomes online and display them on the CALM system studio that is composed of 32 LCD (Columns: 4 $\times$ Rows: 8) monitors that are 19 inches in size so that various personnel can openly study the design outcomes. Also the central 42 inch PDP monitor that offers touch pad capability allows each design outcome to be described and examined by expanding. The concept phase of this development process has elevated to the production of an operating prototype that is being reviewed of its practicality. It is considered that the development of this system will decrease the extreme tendency of depending on digital operation but achieve revitalization of a more realistic and opened studio study environment compared to the individual consulting method of the old study approach.

• 자원환경지질
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• 제21권3호
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• pp.223-234
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• 1988

A large number of gold and/or silver-bearing quartz veins occur in or near Mesozoic granite batholith elongated in a NE-SW direction within the Chungcheong Province. Precambrian schists and gneisses, and Jurassic and Cretaceous granitic rocks serve as hosts for gold and/or silver deposits. On the basis of Ag/Au total production and ore grade ratio, 15 mines may be divided into three major groups: gold-dominant deposits, gold-silver deposits, and silver-dominant deposits. The chemical composition of electrum from skarn deposit (Geodo mine), alaskite-type deposit (Geumjeong mine) and 15 vein deposits was summarized. It was found that the Au content of electrum for vein deposits ranging from 5.2 to 86.5 is lower than that for skarn and alaskite deposits. Among 15 vein deposits, the composition of electrum associated with pyrrhotite is relatively high and has a narrow range of 40.8 to 86.5 atomic % Au, but the Au content of electrum with pyrite is in range of 5.2 to 82.8 atomic %, and is clearly lower than that with pyrrhotite. The grouping of ages for these mines indicates that gold and/or silver mineralizations occurred during two periods in the Mesozoic. Daebo igneous activities are restricted to gold mineralization in the range of 158 to 133 Ma, whereas Bulgugsa igneous activities are related to gold and/or silver mineralization ranging from 108 to 71 Ma. Generally speaking, Jurassic gold-dominant veins have many common characteristics; notably prominent association with pegmatites, simply massive vein morphology, high fineness in the ore concentrates, rarity of silver minerals, and a distinctively simple mineralogy, including sphalerite, galena, chalcopyrite, pyrrhotite and/or pyrite. Although individual deposits exhibit widely differing diversity, Cretaceous gold-silver and silver-dominant veins are characterized by features such as complex vein, low to medium fineness in the ore concentrates and abundance of silver minerals including Ag sulfosalts, Ag sulfides, Ag tellurides and native silver.

• 대한공업교육학회지
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• 제33권1호
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• pp.282-296
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• 2008

기존의 자동차 부품 로봇 용접방법은 노즐을 통하여 $CO_2$ 가스가 확산되는 구조로 되어있어 용접대상물에 노즐간섭으로 인하여 로봇 용접이 불가능한 부위가 많고, 공간이 좁은 부분의 용접은 2차 수작업으로 완성하고 있어 생산성 향상에 걸림돌이었다. 따라서 본 연구에서는 이러한 용접과정을 분석하여 $CO_2$ 가스 소모량을 절약하고, 좁은 공간 부위를 로봇 용접할 수 있는 새로운 특수 용접 노즐을 개발하여 생산성을 향상시키고자 하였다. 본 연구개발에서 설계 제작된 협대역 자동차 부품 로봇 용접용 특수 용접 팁은 2단 구조로서 중단부에 직경 3mm의 구멍을 8개소로 제작하고 $CO_2$ 가스 소모량을 47%이상 절약한 형태로서 용접 결함율이 비교적 낮은 개발품이다. 본 연구의 결과는 국내 자동차 업계에서 사용되는 구형 용접 팁을 중간부에 구멍이 뚫린 2단 구조의 노즐로 대체하면 생산원가를 절감할 수 있다고 판단된다.

• 한국정보통신학회논문지
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• 제20권11호
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• pp.2125-2130
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• 2016

본 논문에서는 모바일 증강현실기술 기반을 활용한 3D전래동화 콘텐츠에 관한 연구이다. 지식기반사회의 핵심콘텐츠 산업으로 주목받고 있는 시공간을 연결하는 SW기술 증강현실(Augmented Reality) 기술을 활용하여 흥미로운 전래동화를 한국어, 중국어, 영어로 자막언어선택으로 외국어학습에 적용한다. 이를 위해 상호작용 AR게임(놀이)으로 재구성하였다. 전래동화는 3D 콘텐츠 제작을 위해 6~8개의 scene으로 분량을 구성하고, 각색하여 번역하였다. 더빙은 모국어로 사용하는 원어민 성우를 통해 표준발음을 사용하여 더빙하였고, 효과음은 장면에 어울리도록 별도 제작하여 편집하였다. 시나리오를 구성하고, 3D 모델구성, 인터렉션 구성, 사운드 이펙트를 구성하고 콘텐츠 메타데이터를 작성한 후, Unity 3D 게임엔진을 실행하여 프로젝트를 생성하고, 스크립터로 기술한다. 재미있고 유익한 전래동화를 ICT기술을 접목한 융복한 콘텐츠로 경험하면서, 첨단기술기반 교육을 수용하며, 생활주변에서 소프트웨어를 인식할 수 있는 기회를 가지게 한다.