• 제목/요약/키워드: Product safety

검색결과 4,204건 처리시간 0.037초

Study on the effect of long-term high temperature irradiation on TRISO fuel

  • Shaimerdenov, Asset;Gizatulin, Shamil;Dyussambayev, Daulet;Askerbekov, Saulet;Ueta, Shohei;Aihara, Jun;Shibata, Taiju;Sakaba, Nariaki
    • Nuclear Engineering and Technology
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    • 제54권8호
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    • pp.2792-2800
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    • 2022
  • In the core of the WWR-K reactor, a long-term irradiation of tristructural isotopic (TRISO)-coated fuel particles (CFPs) with a UO2 kernel was carried out under high-temperature gas-cooled reactor (HTGR)-like operating conditions. The temperature of this TRISO fuel during irradiation varied in the range of 950-1100 ℃. A fission per initial metal atom (FIMA) of uranium burnup of 9.9% was reached. The release of gaseous fission products was measured in-pile. The release-to-birth ratio (R/B) for the fission product isotopes was calculated. Aspects of fuel safety while achieving deep fuel burnup are important and relevant, including maintaining the integrity of the fuel coatings. The main mechanisms of fuel failure are kernel migration, silicon carbide corrosion by palladium, and gas pressure increase inside the CFP. The formation of gaseous fission products and carbon monoxide leads to an increase in the internal pressure in the CFP, which is a dominant failure mechanism of the coatings under this level of burnup. Irradiated fuel compacts were subjected to electric dissociation to isolate the CFPs from the fuel compacts. In addition, nondestructive methods, such as X-ray radiography and gamma spectrometry, were used. The predicted R/B ratio was evaluated using the fission gas release model developed in the high-temperature test reactor (HTTR) project. In the model, both the through-coatings of failed CFPs and as-fabricated uranium contamination were assumed to be sources of the fission gas. The obtained R/B ratio for gaseous fission products allows the finalization and validation of the model for the release of fission products from the CFPs and fuel compacts. The success of the integrity of TRISO fuel irradiated at approximately 9.9% FIMA was demonstrated. A low fuel failure fraction and R/B ratios indicated good performance and reliability of the studied TRISO fuel.

An Analysis of the Effect of Logistics Efficiency on the Export of Korean Agricultural Products to New Southern Countries

  • Park, Hyun-Hee;Cho, Sung-Je
    • Journal of Korea Trade
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    • 제25권1호
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    • pp.169-183
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    • 2021
  • Purpose - This paper analyzes the effect of the agricultural export market for Korea's new southern countries in consideration of logistics efficiency. In order to expand Korean agricultural exports, the logistics performance index, national income, per capita income, consumer price index, distance and FTA are included. Through empirical analysis, the impact of logistics efficiency on Korean agricultural exports is derived and measures are proposed to expand exports in the future. Design/methodology - The analytical model of this study takes into account the import demand factors of the new southern countries for Korean agricultural exports. A research model was established based on prior research based on the gravity model, which is widely used in international trade effect analysis. In particular, logistics efficiency measures the effect on Korean agricultural exports using the logistics performance index and examines the effect by deriving factors for export expansion. Findings - The main findings of this study can be summarized as follows: The higher the logistics efficiency of the new southern countries in exporting Korean agricultural products, the more directly they have an effect on expanding exports. In addition, it was analyzed that the expansion of Korean agricultural exports has a positive effect on the other countries' national income, per capita income, consumer price index, population, and FTA. Based on these results, the importance of efficient logistics management in agricultural exports has been emphasized. Originality/value - There are not many studies on the export of agricultural products by logistics efficiency. However, prior studies that have adapted to manufacturing and other areas suggest that logistics efficiency has a direct effect on exports. This study suggests that Korean agricultural products are directly effective in exporting to new southern countries in terms of logistics efficiency. This can be an important time point in recognizing that logistics capabilities are important to ensure new books and the safety of agricultural products.

녹용 발효 케라틴 펩타이드에 의한 인체 모발 연구 (Study on Effect of Human Hair by Deer Antler Fermented Keratin Peptide)

  • 남개원
    • 대한화장품학회지
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    • 제48권4호
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    • pp.385-392
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    • 2022
  • 본 연구에서는 녹용에 함유한 단백질인 케라틴을 Fervidobacterium islandicum AW-1로 고온 혐기 발효를 통하여 케라틴 펩타이드를 생산하고, 인체 모발 관련한 인자를 확인하여, 화장품 원료로서 케라틴 펩타이드의 가능성을 확인하였다. 모유두 세포주에서 녹용 발효 케라틴 펩타이드를 농도에 따라 세포 독성 및 증식을 확인한 결과, 세포 독성은 나타나지 않았고, 세포 증식 효과를 보였다. 인체 모유두 세포에 대하여 녹용 발효 케라틴 펩타이드에 따른 성장인자의 증가를 확인하여 모발에 영향을 준다고 판단하였다. 이러한 녹용 발효 케라틴 펩타이드를 함유한 화장품을 제조하여 피부 안전성 및 탈모 증상 완화 인체 효력 시험을 수행한 결과, 사용 12 주 후에 제품 사용 전 대비 전체 모발 수의 증가 및 대조군과 비교시 전체 모발 개수의 차이가 통계적으로 유의하게 나타났다. 이를 통해 녹용 발효 케라틴 펩타이드는 기능성 화장품 원료뿐만 아니라 건강 기능 식품 소재로의 가능성을 확인하였다.

선반 스크랩 보강 모르타르의 인장거동에 대한 재료모델 (Material Model for Tensile Behavior of Lathe Scrap Reinforced Mortar)

  • 이현진;배수호 ;권순오
    • 한국건설순환자원학회논문집
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    • 제10권4호
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    • pp.443-449
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    • 2022
  • 섬유보강 콘크리트 제조 시 감섬유 대체재료로서 선반 스크랩을 활용하는 것이 효과적이다. 왜냐하면, 선반 스크랩은 철강 제품의 부산물로서 경제적일 뿐만 아니라 강섬유의 조성과 매우 유사하기 때문이다. 본 연구의 목적은 선반 스크랩 보강 모르타르의 압축강도 및 인장거동을 평가한 후 인장거동에 대한 재료모델을 제안하는 것이다. 이를 위하여 물-결합재비 30 % 및 40 %에 각각에 대하여 선반 스크랩을 총 부피비의 1.5 %를 혼입한 선반 스크랩 보강 모르타르를 제작한 후 압축강도 및 인장거동 등의 역학적 특성을 평가하였다. 또한 선반 스크랩 보강 모르타르의 실험 결과를 바탕으로 인장거동에 대한 재료모델을 제안하였으며, 제안한 모델은 실험 결과와 비교적 잘 일치하는 것으로 나타났다.

향어(Cyprinus carpio)를 활용한 반건제품의 제조 및 관능 특성 (Preparation and Sensory Properties of Semi-dried Israeli Carp Cyprinus carpio)

  • 이창영;박시형;박예은;최유리;이석민;오선화;김진수
    • 한국수산과학회지
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    • 제55권2호
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    • pp.121-128
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    • 2022
  • The aims of this study were to optimize the processing procedure of high-quality semi-alternating temperature dried Israeli carp Cyprinus carpio (SAD-IC) and to investigate the sensory properties of the product. Based on the differences in moisture content of the dorsal and ventral muscles, high quality SAD-IC was prepared by alternating the drying temperature between 4 h at 35℃, and 2 h at 5℃, three times before final drying for 2 h at 35℃. The surface in SAD-IC produced under the optimal alternating-temperature drying process had a markedly superior browning index value and softer texture compared to products produced using constant-temperature drying. SAD-IC produced from dorsal and ventral muscle had significantly superior taste values than the raw material. These results suggest that SAD-IC has the potential to be industrialized.

어업용 씨앵커의 사용실태 분석을 통한 표준화 연구 (A study on standardization through the analysis of the survey on the use of fishery sea anchor)

  • 김남구;김형석;이유원;류경진
    • 수산해양기술연구
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    • 제58권1호
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    • pp.10-18
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    • 2022
  • Fishery sea anchor is widely used for many fishing vessels. However, standardization of the dimension and terminology of the fishery sea anchor has not been achieved, reducing the reliability of the performance and safety of the fishery sea anchor. Therefore, this study researches the reality of usage of fishery sea anchor and then attempts to suggest the development direction of the standard draft as basic data. As a result of the survey on the reality of usage show that various terms were used for each part of the fishery sea anchor (including the incorrect form of non-standard words derived from Japanese) and that the production of this product in the fishery sea anchor market was concentrated on one specific manufacturer. In addition, the main specifications of the fishery sea anchor are set and manufactured based on conventional experience without standards. In the field, there was no standardized drawing for fishery sea anchor and users had low awareness of the main specifications of fishery sea anchor. Therefore, this study suggested the following regarding the fishery sea anchor: standard terms for each part including Korean and English names and standard drawing of sea anchor. It is hoped that this study will contribute to research for the standardization of fishery sea anchor, which will increase in reliability and lead to increased interest in standardization in the fishery field.

Qualitative and quantitative assessment of process related impurities in Brigatinib raw material and formulations using HPLC

  • Attada Tharun;Potnuru Jagadeesh;B Srinivasa Kumar;Kota Thirumala Prasad;Venkateswara Rao Anna
    • 분석과학
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    • 제36권4호
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    • pp.180-190
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    • 2023
  • The presence of process related impurities in any drug or the drug product was associated with its safety, stability and efficacy. The overall literature survey proved that there is no method published on the assessment of process related impurities in brigatinib. In this study, a simple, reliable and stable HPLC qualitative method was reported for quantification of process related impurities with easy and quick extraction procedure. The impurities along with standard brigatinib was resolved on Lichrospher® C18 (250 mm × 4.6 mm; 5 ㎛ particle size) column in room temperature using methanol, acetonitrile, pH 4.5 phosphate buffer in 55:25:20 (v/v) at 1.0 mL/min as mobile phase and UV detection at 261 nm. The method produces well resolved peaks at retention time of 4.60 min, 12.28 min, 3.37 min, 7.34 min and 8.39 min respectively for brigatinib, impurity A, B, C and D. The method produces a very sensitive detection limit of 0.0065 ㎍/mL, 0.0068 ㎍/mL, 0.0053 ㎍/mL and 0.0058 ㎍/mL for impurity A, B, C and D respectively with calibration curve linear in the concentration range of 22.5-135 ㎍/mL for brigatinib and 0.0225-0.135 ㎍/mL for impurities. The method produces all the validation parameters under the acceptable level and doesn't produces any considerable changes in peak area response while minor changes in the developed method conditions. The method can effectively resolve the unknown stress degradation products along with known impurities with less % degradation. The method can efficiently resolve and quantify the impurities in formulation and hence can suitable for the routine quality analysis of brigatinib in raw material and formulation.

Mechanism of improving quality of dry-aged pork loins in scoria-containing onggi, Korean earthenware as a storage container

  • Sung-Su Kim;Dong-Jin Shin;Dong-Gyun Yim;Hye-Jin Kim;Doo Yeon Jung;Hyun-Jun Kim;Cheorun Jo
    • Animal Bioscience
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    • 제36권5호
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    • pp.797-809
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    • 2023
  • Objective: Many scientists have investigated solutions to reduce microbiological risks in dry-aged meat after the dry-aging technology was revived for high quality and value-added premium meat product in the market. This study aimed to investigate the effect of scoria powder in onggi (Korean earthenware) on the meat quality of pork loins during 21 days of dry aging and to elucidate its mechanism of action. Methods: The pork loins were randomly divided into three groups: aged in vacuum-packaging, onggi containing red clay only (OR), and onggi containing 30% red clay and 70% scoria powder (OS). Microbial analyses (total plate count and Lactobacillus spp.) and physicochemical analyses (pH, shear force, volatile basic nitrogen [VBN], water activity, 2-thiobarbituric acid reactive substances, water content, water holding capacity, cooking loss, and color analysis) of aged meat were conducted. Far-infrared ray emission, quantification of immobilized L. sakei and microstructure of onggi were investigated to understand the mechanism. Results: On day 21, the meat aged in OS exhibited lower pH, shear force, VBN, and water activity than those aged in OR, along with an increase in the number of Lactobacillus spp. OS had a smaller pore diameter than OR, implying lower gas permeability, which could promote the growth of L. sakei. Conclusion: OS improved the microbiological safety and storage stability of pork loin during dry aging by increasing number of Lactobacillus spp. possibly due to low permeability of OS.

WTO체제에서 유전자변형식품의 표시제도에 관한 연구: 우리나라 GM식품 표기의 개선방안을 중심으로 (A Study on Labelling for GM foods under the WTO system: Focused on improvements for Korean GM food labelling)

  • 양정미
    • 무역학회지
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    • 제43권5호
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    • pp.179-201
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    • 2018
  • 각 국은 소비자의 알 권리와 선택권을 보장하기 위해 식품표시제도를 의무화한다. 그리고 이러한 각국의 식품표시정책을 수립함에 있어 국제협약 또는 협정에 가입되었다면 이는 모든 서명국에 부과되는 의무라는 복잡한 네트워크에 연결된다. 또한 식품표시제도는 국제무역에 비관세장벽으로 적용할 수 있어 각 국이 식품표시제도를 도입함에 있어 다자적 조화가 필요하며 이를 위해 GATT 20조, SPS, TBT 협정이 적용될 수 있을 것이다. GM식품(Genetically Modified foods)의 안전성과 관련하여서는 여전히 논란이 여전히 끊이지 않고 있다. 더욱이, 우리나라가 GMO를 가장 많이 수입하는 국가라는 사실을 고려한다면 GM식품의 유해성을 차치하더라도 GM식품 관련 표시제도의 명확화 및 GM식품의 혼입기준에 대한 명확한 제시는 소비자들로 하여금 식품 선택에 있어 혼란을 해소할 수 있을 것이다. 따라서 본 논문은 GM식품에 대한 다자적·국내법적 고찰을 통해 우리나라 국내법에서 인용가능한 GM식품관련 법 및 주요 무역국의 국내법을 살펴봄으로써 우리나라 GM식품 표시방법에 대한 개선방안을 제시하고 한다.

Isolation and identification of mosquito-borne zoonotic diseases in slaughterhouse in Daejeon

  • Youngju Kim;Gyurae Kim;Sunkyong Song;Youngshik Jung;Seojin Park;Sang-Joon Lee;Ho-Seong Cho;Yeonsu Oh
    • 한국동물위생학회지
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    • 제46권2호
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    • pp.115-122
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    • 2023
  • This study was performed to investigate the distribution of mosquito vectors related to the zoonotic disease in Daejeon. Samples were taken using a blacklight trap once a month from March to November 2021 at the slaughterhouse in Daejeon. A total of 820 mosquitoes were captured and classified into 5 genera and 8 species. Among the collected mosquitoes, 319 (38.9%) and 295 (35.93%) were Aedes vexans nipponii and Culex pipiens pallens, respectively, making them the dominant species. The overall number of mosquitoes collected started to increase from May and reached the largest value of 329 (40.12%) in June. Trapped mosquitoes are created 72 pools by environmental condition and by species. The pools were tested by PCR methods for 7 zoonotic pathogens. Flavivirus-positive products were confirmed by DNA sequencing. Japanese encephalitis viruses were detected in 3 pools collected from cow lairage (Culex pipiens pallens) in May, cow by-product processing room (Aedes vexans nipponii) in June and cow lairage (Mansonia uniformis) in June. Culex flavivirus were detected in 4 pools. Based on the results of this study, it is considered that continous surveillence of mosquitoes in livestock assembly facilities (slaughterhouse) should be performed for controlling mosquito populations and mediating disease spread by mosquitoes.